Fus cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fus
Entrez Gene ID	317385
Full Name	FUS RNA binding protein
General protein information	Preferred Names FUS RNA binding protein Names RNA-binding protein FUS 16) in malignant liposarcoma) 16) malignant liposarcoma fused in sarcoma RNA binding protein fusion (involved in t(12 fusion, derived from t(12 fusion, derived from t(12;16) malignant liposarcoma
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q37

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012137.1	NP_001012137.1	RNA-binding protein FUS
XM_006230290.3	XP_006230352.1	RNA-binding protein FUS isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Fus	NP_631888.1
Canis lupus familiaris (dog)	FUS	XP_005621295.1
Bos taurus (cattle)	FUS	NP_776337.1
Rattus norvegicus (Norway rat)	Fus	NP_001012137.1

Gene Ontology
Bibliography

Related articles in PubMed

FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
Yamaguchi A, Takanashi K
Scientific reports635195(2016 Oct)

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Kapeli K, Pratt GA, Vu AQ, Hutt KR, Martinez FJ, Sundararaman B, Batra R, Freese P, Lambert NJ, Huelga SC, Chun SJ, Liang TY, Chang J, Donohue JP, Shiue L, Zhang J, Zhu H, Cambi F, Kasarskis E, Hoon S, Ares M Jr, Burge CB, Ravits J, Rigo F, Yeo GW
Nature communications712143(2016 Jul)

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP.
Yu Y, Reed R
Proceedings of the National Academy of Sciences of the United States of America112(28)8608-13(2015 Jul)

Self-assembled FUS binds active chromatin and regulates gene transcription.
Yang L, Gal J, Chen J, Zhu H
Proceedings of the National Academy of Sciences of the United States of America111(50)17809-14(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Tau mRNA is identified as a physiological splicing target of FUS.
Title: Loss of fused in sarcoma (FUS) promotes pathological Tau splicing.

Findings suggest that TDP-43 and FUS play an important role in development and that constant and robust expression of the genes in motor neurons may render the neurons vulnerable to pathogenic mutation of the TDP-43 or the FUS gene.
Title: Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime.

results suggested that TLS (FUS) might be involved in a calcium-dependent trafficking of specific NR1 splice variants in retinal ganglion cells
Title: TLS interaction with NMDA R1 splice variant in retinal ganglion cell line RGC-5.

The following Fus gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fus cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13748	NM_001012137.1 Latest version!	Rattus norvegicus FUS RNA binding protein (Fus), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa23446	XM_006230290.3 Latest version!	Rattus norvegicus fused in sarcoma RNA binding protein (Fus), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fus ( NM_001012137.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012137.1 Rattus norvegicus FUS RNA binding protein (Fus), mRNA.

Price & Availability↑

CloneID	ORa13748
Clone ID Related Accession (Same CDS sequence)	NM_001012137.1
Accession Version	NM_001012137.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	RNA-binding protein FUS
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087153.1. On Feb 11, 2005 this sequence version replaced XM_228776.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087153.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCAA ACGACTATAC CCAACAAGCA ACTCAAAGCT ATGGGGCCTA TCCTACCCAG 
CCTGGGCAGG GCTATTCCCA ACAGAGCAAT CAGCCCTATG GCCAGCAGAG TTACAGTGGT 
TATGGCCAAT CAGCTGACAC TTCAGGATAC GGCCAGAGCA GCTATGGTTC TTCTTATGGA 
CAGACCCAAA ACACAGGCTA TGGAACTCAG TCAGCACCCC AGGGATATGG TTCCACTGGT 
GGCTATGGCA GCAGCCAAAG TTCCCAGTCT TCTTATGGGC AGCAGTCCTC CTACCCCGGT 
TATGGCCAAC AGCCAGCTCC TAGTAGCACC TCAGGAAGTT ATGGTGGAAG TTCTCAGAGC 
AGCAGCTATG GGCAGCCCCA GAGTGGAGGC TATGGTCAAC AGTCTGGCTA TGGTGGACAG 
CAACAAAGCT ACGGACAGCA ACAAAGCTCC TATAACCCAC CTCAGGGTTA TGGACAACAG 
AACCAGTACA ACAGCAGCAG TGGAGGTGGT GGAGGGGGTG GTGGAGGCAA CTATGGCCAA 
GATCAGTCCT CTATGAGTGG CGGCGGCGGT GGTGGTGGTT ATGGCAATCA GGACCAGAGT 
GGTGGCGGCG GTGGTGGCTA CGGGGGAGGC CAGCAGGATC GTGGGGGCCG TGGCAGGGGC 
GGTGGAGGTG GTTACAACCG AAGCAGTGGT GGCTATGAAC CCAGAGGCCG TGGAGGTGGC 
CGAGGAGGCA GAGGCGGCAT GGGCGGAAGT GACCGTGGTG GCTTCAATAA ATTTGGTGGT 
CCTCGGGATC AAGGATCTCG TCATGATTCT GAACAGGATA ATTCAGACAA TAATACCATC 
TTCGTGCAAG GCCTAGGCGA GAATGTTACA ATTGAATCTG TGGCGGATTA CTTCAAGCAG 
ATTGGAATTA TTAAGACAAA CAAGAAAACT GGACAGCCTA TGATTAATTT GTATACAGAC 
AGAGAAACTG GCAAGTTGAA GGGTGAGGCA ACAGTCTCAT TTGATGACCC ACCTTCTGCT 
AAAGCTGCAA TCGACTGGTT TGATGGAAAA GAATTCTCTG GGAATCCTAT TAAAGTTTCA 
TTTGCTACCC GGCGTGCTGA CTTCAACCGG GGTGGTGGAA ATGGTCGTGG AGGCCGAGGG 
CGAGGAGGAC CCATGGGCCG TGGAGGCTAT GGAGGAGGTG GCAGCGGTGG TGGTGGCCGG 
GGAGGATTTC CCAGTGGAGG TGGTGGAGGT GGAGGACAGC AACGAGCTGG GGACTGGAAG 
TGTCCTAATC CTACATGTGA GAACATGAAC TTCTCTTGGA GAAGTGAATG CAACCAGTGT 
AAGGCACCTA AGCCAGATGG CCCAGGAGGG GGACCAGGAG GCTCTCATAT GGGGGGAAAC 
TACGGAGATG ATCGGCGTGG CAGAGGAGGA TATGATCGGG GCGGCTACCG GGGCCGAGGA 
GGGGACCGAG GGGGCTTCAG AGGGGGCCGG GGTGGTGGGG ACAGAGGTGG TTTTGGCCCT 
GGCAAGATGG ACTCCAGGGG TGAGCACAGA CAGGATCGCA GGGAGAGGCC ATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012137.1
CDS	66..1622
Translation	MASNDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQYNSSSGGGGGGGGGNYGQDQSSMSGGGGGGGYGNQDQSGGGGGGYGGGQQDRGGRGRGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY

Target ORF information:

RefSeq Version	NM_001012137.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FUS RNA binding protein (Fus), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012137.1

ORF Insert Sequence:

ATGGCTTCAA ACGACTATAC CCAACAAGCA ACTCAAAGCT ATGGGGCCTA TCCTACCCAG 
CCTGGGCAGG GCTATTCCCA ACAGAGCAAT CAGCCCTATG GCCAGCAGAG TTACAGTGGT 
TATGGCCAAT CAGCTGACAC TTCAGGATAC GGCCAGAGCA GCTATGGTTC TTCTTATGGA 
CAGACCCAAA ACACAGGCTA TGGAACTCAG TCAGCACCCC AGGGATATGG TTCCACTGGT 
GGCTATGGCA GCAGCCAAAG TTCCCAGTCT TCTTATGGGC AGCAGTCCTC CTACCCCGGT 
TATGGCCAAC AGCCAGCTCC TAGTAGCACC TCAGGAAGTT ATGGTGGAAG TTCTCAGAGC 
AGCAGCTATG GGCAGCCCCA GAGTGGAGGC TATGGTCAAC AGTCTGGCTA TGGTGGACAG 
CAACAAAGCT ACGGACAGCA ACAAAGCTCC TATAACCCAC CTCAGGGTTA TGGACAACAG 
AACCAGTACA ACAGCAGCAG TGGAGGTGGT GGAGGGGGTG GTGGAGGCAA CTATGGCCAA 
GATCAGTCCT CTATGAGTGG CGGCGGCGGT GGTGGTGGTT ATGGCAATCA GGACCAGAGT 
GGTGGCGGCG GTGGTGGCTA CGGGGGAGGC CAGCAGGATC GTGGGGGCCG TGGCAGGGGC 
GGTGGAGGTG GTTACAACCG AAGCAGTGGT GGCTATGAAC CCAGAGGCCG TGGAGGTGGC 
CGAGGAGGCA GAGGCGGCAT GGGCGGAAGT GACCGTGGTG GCTTCAATAA ATTTGGTGGT 
CCTCGGGATC AAGGATCTCG TCATGATTCT GAACAGGATA ATTCAGACAA TAATACCATC 
TTCGTGCAAG GCCTAGGCGA GAATGTTACA ATTGAATCTG TGGCGGATTA CTTCAAGCAG 
ATTGGAATTA TTAAGACAAA CAAGAAAACT GGACAGCCTA TGATTAATTT GTATACAGAC 
AGAGAAACTG GCAAGTTGAA GGGTGAGGCA ACAGTCTCAT TTGATGACCC ACCTTCTGCT 
AAAGCTGCAA TCGACTGGTT TGATGGAAAA GAATTCTCTG GGAATCCTAT TAAAGTTTCA 
TTTGCTACCC GGCGTGCTGA CTTCAACCGG GGTGGTGGAA ATGGTCGTGG AGGCCGAGGG 
CGAGGAGGAC CCATGGGCCG TGGAGGCTAT GGAGGAGGTG GCAGCGGTGG TGGTGGCCGG 
GGAGGATTTC CCAGTGGAGG TGGTGGAGGT GGAGGACAGC AACGAGCTGG GGACTGGAAG 
TGTCCTAATC CTACATGTGA GAACATGAAC TTCTCTTGGA GAAGTGAATG CAACCAGTGT 
AAGGCACCTA AGCCAGATGG CCCAGGAGGG GGACCAGGAG GCTCTCATAT GGGGGGAAAC 
TACGGAGATG ATCGGCGTGG CAGAGGAGGA TATGATCGGG GCGGCTACCG GGGCCGAGGA 
GGGGACCGAG GGGGCTTCAG AGGGGGCCGG GGTGGTGGGG ACAGAGGTGG TTTTGGCCCT 
GGCAAGATGG ACTCCAGGGG TGAGCACAGA CAGGATCGCA GGGAGAGGCC ATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fus ( XM_006230290.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230352.1 Rattus norvegicus fused in sarcoma RNA binding protein (Fus), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23446
Clone ID Related Accession (Same CDS sequence)	XM_006230290.3
Accession Version	XM_006230290.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	RNA-binding protein FUS isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230290.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAA ACGACTATAC CCAACAAGCA ACTCAAAGCT ATGGGGCCTA TCCTACCCAG 
CCTGGGCAGG GCTATTCCCA ACAGAGCAAT CAGCCCTATG GCCAGCAGAG TTACAGTGGT 
TATGGCCAAT CAGCTGACAC TTCAGGATAC GGCCAGAGCA GCTATGGTTC TTCTTATGGA 
CAGACCCAAA ACAGCTATGG AACTCAGTCA GCACCCCAGG GATATGGTTC CACTGGTGGC 
TATGGCAGCA GCCAAAGTTC CCAGTCTTCT TATGGGCAGC AGTCCTCCTA CCCCGGTTAT 
GGCCAACAGC CAGCTCCTAG TAGCACCTCA GGAAGTTATG GTGGAAGTTC TCAGAGCAGC 
AGCTATGGGC AGCCCCAGAG TGGAGGCTAT GGTCAACAGT CTGGCTATGG TGGACAGCAA 
CAAAGCTACG GACAGCAACA AAGCTCCTAT AACCCACCTC AGGGTTATGG ACAACAGAAC 
CAGTACAACA GCAGCAGTGG AGGTGGTGGA GGGGGTGGTG GAGGCAACTA TGGCCAAGAT 
CAGTCCTCTA TGAGTGGCGG CGGCGGTGGT GGTGGTTATG GCAATCAGGA CCAGAGTGGT 
GGCGGCGGTG GTGGCTACGG GGGAGGCCAG CAGGATCGTG GGGGCCGTGG CAGGGGCGGT 
GGAGGTGGTT ACAACCGAAG CAGTGGTGGC TATGAACCCA GAGGCCGTGG AGGTGGCCGA 
GGAGGCAGAG GCGGCATGGG CGGAAGTGAC CGTGGTGGCT TCAATAAATT TGGTGGTCCT 
CGGGATCAAG GATCTCGTCA TGATTCTGAA CAGGATAATT CAGACAATAA TACCATCTTC 
GTGCAAGGCC TAGGCGAGAA TGTTACAATT GAATCTGTGG CGGATTACTT CAAGCAGATT 
GGAATTATTA AGACAAACAA GAAAACTGGA CAGCCTATGA TTAATTTGTA TACAGACAGA 
GAAACTGGCA AGTTGAAGGG TGAGGCAACA GTCTCATTTG ATGACCCACC TTCTGCTAAA 
GCTGCAATCG ACTGGTTTGA TGGAAAAGAA TTCTCTGGGA ATCCTATTAA AGTTTCATTT 
GCTACCCGGC GTGCTGACTT CAACCGGGGT GGTGGAAATG GTCGTGGAGG CCGAGGGCGA 
GGAGGACCCA TGGGCCGTGG AGGCTATGGA GGAGGTGGCA GCGGTGGTGG TGGCCGGGGA 
GGATTTCCCA GTGGAGGTGG TGGAGGTGGA GGACAGCAAC GAGCTGGGGA CTGGAAGTGT 
CCTAATCCTA CATGTGAGAA CATGAACTTC TCTTGGAGAA GTGAATGCAA CCAGTGTAAG 
GCACCTAAGC CAGATGGCCC AGGAGGGGGA CCAGGAGGCT CTCATATGGG GGGAAACTAC 
GGAGATGATC GGCGTGGCAG AGGAGGATAT GATCGGGGCG GCTACCGGGG CCGAGGAGGG 
GACCGAGGGG GCTTCAGAGG GGGCCGGGGT GGTGGGGACA GAGGTGGTTT TGGCCCTGGC 
AAGATGGACT CCAGGGGTGA GCACAGACAG GATCGCAGGG AGAGGCCATA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230352.1
CDS	95..1648
Translation	MASNDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNSYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQYNSSSGGGGGGGGGNYGQDQSSMSGGGGGGGYGNQDQSGGGGGGYGGGQQDRGGRGRGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY

Target ORF information:

RefSeq Version	XM_006230290.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fused in sarcoma RNA binding protein (Fus), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230290.3

ORF Insert Sequence:

ATGGCTTCAA ACGACTATAC CCAACAAGCA ACTCAAAGCT ATGGGGCCTA TCCTACCCAG 
CCTGGGCAGG GCTATTCCCA ACAGAGCAAT CAGCCCTATG GCCAGCAGAG TTACAGTGGT 
TATGGCCAAT CAGCTGACAC TTCAGGATAC GGCCAGAGCA GCTATGGTTC TTCTTATGGA 
CAGACCCAAA ACAGCTATGG AACTCAGTCA GCACCCCAGG GATATGGTTC CACTGGTGGC 
TATGGCAGCA GCCAAAGTTC CCAGTCTTCT TATGGGCAGC AGTCCTCCTA CCCCGGTTAT 
GGCCAACAGC CAGCTCCTAG TAGCACCTCA GGAAGTTATG GTGGAAGTTC TCAGAGCAGC 
AGCTATGGGC AGCCCCAGAG TGGAGGCTAT GGTCAACAGT CTGGCTATGG TGGACAGCAA 
CAAAGCTACG GACAGCAACA AAGCTCCTAT AACCCACCTC AGGGTTATGG ACAACAGAAC 
CAGTACAACA GCAGCAGTGG AGGTGGTGGA GGGGGTGGTG GAGGCAACTA TGGCCAAGAT 
CAGTCCTCTA TGAGTGGCGG CGGCGGTGGT GGTGGTTATG GCAATCAGGA CCAGAGTGGT 
GGCGGCGGTG GTGGCTACGG GGGAGGCCAG CAGGATCGTG GGGGCCGTGG CAGGGGCGGT 
GGAGGTGGTT ACAACCGAAG CAGTGGTGGC TATGAACCCA GAGGCCGTGG AGGTGGCCGA 
GGAGGCAGAG GCGGCATGGG CGGAAGTGAC CGTGGTGGCT TCAATAAATT TGGTGGTCCT 
CGGGATCAAG GATCTCGTCA TGATTCTGAA CAGGATAATT CAGACAATAA TACCATCTTC 
GTGCAAGGCC TAGGCGAGAA TGTTACAATT GAATCTGTGG CGGATTACTT CAAGCAGATT 
GGAATTATTA AGACAAACAA GAAAACTGGA CAGCCTATGA TTAATTTGTA TACAGACAGA 
GAAACTGGCA AGTTGAAGGG TGAGGCAACA GTCTCATTTG ATGACCCACC TTCTGCTAAA 
GCTGCAATCG ACTGGTTTGA TGGAAAAGAA TTCTCTGGGA ATCCTATTAA AGTTTCATTT 
GCTACCCGGC GTGCTGACTT CAACCGGGGT GGTGGAAATG GTCGTGGAGG CCGAGGGCGA 
GGAGGACCCA TGGGCCGTGG AGGCTATGGA GGAGGTGGCA GCGGTGGTGG TGGCCGGGGA 
GGATTTCCCA GTGGAGGTGG TGGAGGTGGA GGACAGCAAC GAGCTGGGGA CTGGAAGTGT 
CCTAATCCTA CATGTGAGAA CATGAACTTC TCTTGGAGAA GTGAATGCAA CCAGTGTAAG 
GCACCTAAGC CAGATGGCCC AGGAGGGGGA CCAGGAGGCT CTCATATGGG GGGAAACTAC 
GGAGATGATC GGCGTGGCAG AGGAGGATAT GATCGGGGCG GCTACCGGGG CCGAGGAGGG 
GACCGAGGGG GCTTCAGAGG GGGCCGGGGT GGTGGGGACA GAGGTGGTTT TGGCCCTGGC 
AAGATGGACT CCAGGGGTGA GCACAGACAG GATCGCAGGG AGAGGCCATA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
Scientific reports635195(2016 Oct)
Yamaguchi A,Takanashi K

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Nature communications712143(2016 Jul)
Kapeli K,Pratt GA,Vu AQ,Hutt KR,Martinez FJ,Sundararaman B,Batra R,Freese P,Lambert NJ,Huelga SC,Chun SJ,Liang TY,Chang J,Donohue JP,Shiue L,Zhang J,Zhu H,Cambi F,Kasarskis E,Hoon S,Ares M Jr,Burge CB,Ravits J,Rigo F,Yeo GW

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP.
Proceedings of the National Academy of Sciences of the United States of America112(28)8608-13(2015 Jul)
Yu Y,Reed R

Self-assembled FUS binds active chromatin and regulates gene transcription.
Proceedings of the National Academy of Sciences of the United States of America111(50)17809-14(2014 Dec)
Yang L,Gal J,Chen J,Zhu H

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Fus cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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