The following Birc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Birc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa47283 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001170596.2 | |
| Accession Version | NM_001170596.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 14598bp) Protein sequence SNP |
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| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-31 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | baculoviral IAP repeat-containing protein 6 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01042145.1, AAHX01042144.1, AAHX01042143.1, AAHX01042141.1, AAHX01042140.1, AAHX01042139.1 and AAHX01042138.1. On Dec 9, 2014 this sequence version replaced NM_001170596.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. No single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGACTG GCTGTGGTGC TGCACCTCCC GGGACTGTCA CTGAGCCGCT TCCCAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001164067.1 |
| CDS | 139..14736 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001170596.2 |
1 | ATGGTGACTG GCTGTGGTGC TGCACCTCCC GGGACTGTCA CTGAGCCGCT TCCCAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Defining the membrane proteome of NK cells. |
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE. |
Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality. |
The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9. |
BRUCE, a giant E2/E3 ubiquitin ligase and inhibitor of apoptosis protein of the trans-Golgi network, is required for normal placenta development and mouse survival. |
