The following Thoc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thoc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa40225 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001191756.1 | |
| Accession Version | NM_001191756.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4785bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-31 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | THO complex subunit 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC124926.7 and AABR07073548.1. On Jul 17, 2010 this sequence version replaced XM_233081.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. | |
1 | ATGGCGGCCG CGACTGTGGT GGTTCCCGCA GAGTGGATAA AGAACTGGGA GAAATCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001178685.1 |
| CDS | 31..4815 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001191756.1 |
1 | ATGGCGGCCG CGACTGTGGT GGTTCCCGCA GAGTGGATAA AGAACTGGGA GAAATCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa40224 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006257504.3 | |
| Accession Version | XM_006257504.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4866bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | THO complex subunit 2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006257504.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGGCCG CGACTGTGGT GGTTCCCGCA GAGTGGATAA AGAACTGGGA GAAATCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006257566.1 |
| CDS | 43..4908 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006257504.3 |
1 | ATGGCGGCCG CGACTGTGGT GGTTCCCGCA GAGTGGATAA AGAACTGGGA GAAATCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
THOC2 Mutations Implicate mRNA-Export Pathway in X-Linked Intellectual Disability. |
The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming. |
A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia. |
A quantitative telomeric chromatin isolation protocol identifies different telomeric states. |
The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export. |
