Lrrc26 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc26
Entrez Gene ID	311803
Full Name	leucine rich repeat containing 26
Synonyms	RGD1308398
General protein information	Preferred Names leucine rich repeat containing 26 Names leucine-rich repeat-containing protein 26 BK channel auxiliary gamma subunit LRRC26 BK channel auxilliary gamma subunit LRRC26
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014053.1	NP_001014075.1	leucine-rich repeat-containing protein 26 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LRRC26	XP_002691732.1
Pan troglodytes (chimpanzee)	LRRC26	XP_520644.2
	LRRC26	XP_001090425.1
Canis lupus familiaris (dog)	LRRC26	XP_848545.2
Homo sapiens (human)	LRRC26	NP_001013675.1
Gallus gallus (chicken)	LRRC26	XP_004945818.1
Mus musculus (house mouse)	Lrrc26	NP_666229.1
Rattus norvegicus (Norway rat)	Lrrc26	NP_001014075.1

Gene Ontology
Bibliography

Related articles in PubMed

LRRC26 is a functional BK channel auxiliary ? subunit in arterial smooth muscle cells.
Evanson KW, Bannister JP, Leo MD, Jaggar JH
Circulation research115(4)423-31(2014 Aug)

BK potassium channel modulation by leucine-rich repeat-containing proteins.
Yan J, Aldrich RW
Proceedings of the National Academy of Sciences of the United States of America109(20)7917-22(2012 May)

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium.
Yan J, Aldrich RW
Nature466(7305)513-6(2010 Jul)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study indicates that arterial myocytes express LRRC26 which functions as BK channel gamma subunit.
Title: LRRC26 is a functional BK channel auxiliary ? subunit in arterial smooth muscle cells.

The following Lrrc26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04789	NM_001014053.1 Latest version!	Rattus norvegicus leucine rich repeat containing 26 (Lrrc26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc26 ( NM_001014053.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001014075.1 Rattus norvegicus leucine rich repeat containing 26 (Lrrc26), mRNA.

Price & Availability↑

CloneID	ORa04789
Clone ID Related Accession (Same CDS sequence)	NM_001014053.1
Accession Version	NM_001014053.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Rattus norvegicus(Norway rat)
Product	leucine-rich repeat-containing protein 26 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC061729.1. On Apr 20, 2005 this sequence version replaced XM_231053.3. ##Evidence-Data-START## Transcript exon combination :: BC061729.1, DN948658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689601, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGGTT CTTTTTTCTC GCGGCTTCCG CCGCAACTCT CTCTGCTGCT GCTGCTGCTG 
CTGCTGTTGT CGTGGAGACG AGTCTGGACC CAGGAGCACA TTGGAACTGA CCCTTCCAAA 
TCCCCGGTGG CCCCCGTATG CCCCGAGGCA TGTTCATGTT CACCAGGAGG CAAGGCCAAT 
TGCTCCGCGC TGGCGCTGCC CGCGGTACCG GCGGGCCTGA GCTGGCAAGT ACGCTCACTG 
CTGCTGGATC GCAATCGAGT GAGCACACTA CCTCCAGGTG CCTTCGCCGA TGCAGGCGCA 
CTGCTATACC TAGTCCTGCG GGAGAACCGG CTTCGGTCGG TGCACGCGCG AGCTTTCTGG 
GGTCTGGGAG TGTTGCAACG GCTGGACCTG AGCTCCAACC AGCTGGAAAC TCTGTCTCCT 
GGCACCTTCA CGCCTCTGCG AGCGCTGAGT TTCCTCTCCC TAGCGGGTAA CCGGCTGGCA 
CTCCTGGAGC CCTCGATCCT GGGCCCGCTC CCTTTACTGC GGGTGCTCAG CCTGCAGGAC 
AATTCACTAT CGGCACTCGA GGCGGGTTTG CTGAATAGCT TGCCTGCCCT CGACGTGTTG 
CGCTTGCATG GCAACCCCTG GGCGTGCAGC TGCGCGCTGC GCCCGCTTTG CACCTGGCTG 
CGTAAGCACC CGCGTCCCAC TTCAGAAACT GAGACCCTGC TCTGTGTGTC TCCAAAACTT 
CAAACGCTCA ACCTACTGAC AGACTTTCCG GACAACGCCT TCAAACAGTG CACGCAGTCA 
CTCGCTGCGC GAGACCTGGC GGTGGTCTAT GCTCTCGGGC CGGCCTCTTT CCTTGCCAGT 
TTAGCCATCT GCCTGGCATT GGGCTCGGTA CTCACTGCTT GTGGTGCACG GCGCCGCCGC 
CGCCGCACCA CAGTGCGCCA CTTAATAAGG AGACAGCCAG ACCCCGAGGG CCCAGCCTCC 
CTGGAGGATG TTGGGAGCCC TACAACAACA GCTATCCAAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014075.1
CDS	125..1129
Translation	MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRRTTVRHLIRRQPDPEGPASLEDVGSPTTTAIQA

Target ORF information:

RefSeq Version	NM_001014053.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 26 (Lrrc26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014053.1

ORF Insert Sequence:

ATGAGGGGTT CTTTTTTCTC GCGGCTTCCG CCGCAACTCT CTCTGCTGCT GCTGCTGCTG 
CTGCTGTTGT CGTGGAGACG AGTCTGGACC CAGGAGCACA TTGGAACTGA CCCTTCCAAA 
TCCCCGGTGG CCCCCGTATG CCCCGAGGCA TGTTCATGTT CACCAGGAGG CAAGGCCAAT 
TGCTCCGCGC TGGCGCTGCC CGCGGTACCG GCGGGCCTGA GCTGGCAAGT ACGCTCACTG 
CTGCTGGATC GCAATCGAGT GAGCACACTA CCTCCAGGTG CCTTCGCCGA TGCAGGCGCA 
CTGCTATACC TAGTCCTGCG GGAGAACCGG CTTCGGTCGG TGCACGCGCG AGCTTTCTGG 
GGTCTGGGAG TGTTGCAACG GCTGGACCTG AGCTCCAACC AGCTGGAAAC TCTGTCTCCT 
GGCACCTTCA CGCCTCTGCG AGCGCTGAGT TTCCTCTCCC TAGCGGGTAA CCGGCTGGCA 
CTCCTGGAGC CCTCGATCCT GGGCCCGCTC CCTTTACTGC GGGTGCTCAG CCTGCAGGAC 
AATTCACTAT CGGCACTCGA GGCGGGTTTG CTGAATAGCT TGCCTGCCCT CGACGTGTTG 
CGCTTGCATG GCAACCCCTG GGCGTGCAGC TGCGCGCTGC GCCCGCTTTG CACCTGGCTG 
CGTAAGCACC CGCGTCCCAC TTCAGAAACT GAGACCCTGC TCTGTGTGTC TCCAAAACTT 
CAAACGCTCA ACCTACTGAC AGACTTTCCG GACAACGCCT TCAAACAGTG CACGCAGTCA 
CTCGCTGCGC GAGACCTGGC GGTGGTCTAT GCTCTCGGGC CGGCCTCTTT CCTTGCCAGT 
TTAGCCATCT GCCTGGCATT GGGCTCGGTA CTCACTGCTT GTGGTGCACG GCGCCGCCGC 
CGCCGCACCA CAGTGCGCCA CTTAATAAGG AGACAGCCAG ACCCCGAGGG CCCAGCCTCC 
CTGGAGGATG TTGGGAGCCC TACAACAACA GCTATCCAAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LRRC26 is a functional BK channel auxiliary ? subunit in arterial smooth muscle cells.
Circulation research115(4)423-31(2014 Aug)
Evanson KW,Bannister JP,Leo MD,Jaggar JH

BK potassium channel modulation by leucine-rich repeat-containing proteins.
Proceedings of the National Academy of Sciences of the United States of America109(20)7917-22(2012 May)
Yan J,Aldrich RW

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium.
Nature466(7305)513-6(2010 Jul)
Yan J,Aldrich RW

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR