Slc4a11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc4a11
Entrez Gene ID	311423
Full Name	solute carrier family 4 member 11
General protein information	Preferred Names solute carrier family 4 member 11 Names sodium bicarbonate transporter-like protein 11 solute carrier family 4, sodium bicarbonate transporter-like, member 11 solute carrier family 4, sodium borate transporter, member 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107775.1	NP_001101245.1	sodium bicarbonate transporter-like protein 11

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC4A11	NP_001167561.1
Canis lupus familiaris (dog)	SLC4A11	XP_005634909.1
Mus musculus (house mouse)	Slc4a11	NP_001074631.1
	SLC4A11	XP_002798266.1
Gallus gallus (chicken)	SLC4A11	XP_004936342.1
Caenorhabditis elegans (roundworm)	abts-3	NP_001033333.1
Pan troglodytes (chimpanzee)	SLC4A11	XP_001160838.1
Danio rerio (zebrafish)	slc4a11	NP_001153300.1
Rattus norvegicus (Norway rat)	Slc4a11	NP_001101245.1
Bos taurus (cattle)	SLC4A11	NP_001178243.1
Xenopus tropicalis (tropical clawed frog)	slc4a11	XP_002936409.2

Gene Ontology
Bibliography

Related articles in PubMed

The cytoplasmic domain is essential for transport function of the integral membrane transport protein SLC4A11.
Loganathan SK, Lukowski CM, Casey JR
American journal of physiology. Cell physiology310(2)C161-74(2016 Jan)

Oligomerization of SLC4A11 protein and the severity of FECD and CHED2 corneal dystrophies caused by SLC4A11 mutations.
Vilas GL, Loganathan SK, Quon A, Sundaresan P, Vithana EN, Casey J
Human mutation33(2)419-28(2012 Feb)

SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.
Gr?ger N, Fr?hlich H, Maier H, Olbrich A, Kostin S, Braun T, Boettger T
The Journal of biological chemistry285(19)14467-74(2010 May)

NaBC1 is a ubiquitous electrogenic Na+ -coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation.
Park M, Li Q, Shcheynikov N, Zeng W, Muallem S
Molecular cell16(3)331-41(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We conclude that SLC4A11 is a rare integral membrane protein in which the CD has strong associations with the integral MD, which contributes to membrane transport function.
Title: The cytoplasmic domain is essential for transport function of the integral membrane transport protein SLC4A11.

The following Slc4a11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc4a11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05935	NM_001107775.1 Latest version!	Rattus norvegicus solute carrier family 4 member 11 (Slc4a11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc4a11 ( NM_001107775.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101245.1 Rattus norvegicus solute carrier family 4 member 11 (Slc4a11), mRNA.

Price & Availability↑

CloneID	ORa05935
Clone ID Related Accession (Same CDS sequence)	NM_001107775.1
Accession Version	NM_001107775.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2589bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	sodium bicarbonate transporter-like protein 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_001081183.1, XM_230605.4. ##Evidence-Data-START## Transcript exon combination :: FQ225785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGTCACAGA ATGAACACTG TCAGGACTCC GGTGAATACT TCTCAGCCGC CACTCTGGGA 
TACTTCAAGA ATGACACAGA TGATAACCCT GACGTCCGGG AGGACAGCCT GGGGGATGAG 
GTCTTTGACA CCGTCAACTC CTCCATTGTG TCTGGCGAGA GCATCCGTTT TTTTGTCAAT 
GTCAACCTTG AAGTGCAGCC TTCCAAATCT GACATAGAAG CTGCAACTGG AGGCTGCGTG 
CTCTTACACA CCTCCCGCAA GTATCTGAAA TTAAAGAACT TCGAGGAAGA GGTCCGTGCA 
CACCGTGACC TGGATGGCTT CCTGGCCCAG GCCAGCATCA TCCTGAATGA GACAGCTACC 
TCACTGGATG ATGTGCTCCG AACTATGCTA AACCGCTTTG CCCAGGACCC CAACCATGCA 
GAGCCTGATT GTGACCTGGA CCTGCTCATG GCTAAGCTCT TTACAGATGC TGGGGGCCCC 
ATGGAGAGTA AAGTCCACCT GCTGTCAGAT ACCATCCAGG GAGTGACCGC CACTGTCAGA 
GGACTGCAGT ACGAGCAGTC ATGGCTCTGC ATCGTCTGTA CCATGAAGTC CCTACAGAAG 
CGGCATGTGT GTATCAGCCG CCTGGTTCGG CCACAGAACT GGGGGGAAAA CTCCTGTGAG 
GTTCGCTTTG TCATCCTGGT GCTGGCCCCA CCCAAGATGA AAAGCACCAA GACTGCGATG 
GAGGTGGCAC GCACATTCGC CACCATGTTC TCCGACATCA CCTTCCGCCA GAAGCTCCTG 
AAGACCCGCA CAGAGGAAGA GTTCAAGGAG GCTTTGGTGC ACCAGAGACA GCTGCTCACC 
ATGATGATGC CAAGAGCAGC CGGGCACAGC ATGAGCTCCC TCCATACTCA CAGACACCCT 
CGGCCCCCGA AATGCAAGGA CTTTTTCCCG TTTGGGAAAG GCATCTGGGT GGACATCATG 
CGCAGGTTCC CTGTGTACCC GCTGGACTTC ACGGACGGCA TCATTGGGAA AGGCAAGACT 
GTCGGCAAAT ATGTCACCAC CACGCTCTTC CTCTACTTCG CCTGCCTCTT ACCGACCATT 
GCTTTTGGAT CCCTCAACGA TGAGAACACA AACGGAGCCA TCGATGTGCA GAAGACCATA 
GCAGGACAGA GCATCGGAGG CCTCTTGTAT GCACTGTTCT CTGGGCAGCC CCTGGTGATC 
CTGTTGACAA CCGCACCCCT GGCCATCTAC ACCCAGGTGA TCCGGGTCAT CTGTGATGAC 
TACAACCTGG ACTTCAACGC CTTCTATGCG TGGACAGGCC TGTGGAACAG CTTCTTCCTT 
GCGCTTTATG CCTTCCTCAA CCTCAGCCTG CTTATGAATC TCTTTAAGAG GTCAACAGAG 
GAGATCATTG CTCTGTTCAT TTCCATCACG TTTGTGCTGG ACGCTGTCAA GGGCATGGTC 
AAAATCTTCT GGAAGTACTA CTATGGTCAC CACTACCACA CAAAAAGGAC TTCCTCCTTG 
GCAAGCCTGT TGGGCATTAG CAGAAGCCCC AACACCAGTC TCCACACTGC ACTCAACACC 
AGCTTCTTGG CCAGCCCCAT AGAGATGACT ACAGCCAGCA GCCCCATCAG TACACACTCC 
AACCAGGCTA CTGCAGTGCT CAGCCTCCTC ATCATGCTGG GCACACTCTG GCTGGGCTAC 
ACCCTCTACC AGTTCAAGAA AAGCCCCTAC CTGCACCCAT GTGTGCGTGA GACCCTGTCT 
GACTGTGCCC TGCCTATCGC CGTGCTCTCC TTCTCCCTCA TCAGCTCCTA TGGCTTCCAG 
GAAATTGAGA TGAGCAAGTT CCGGTACAAC CCCAGCGAGA GCCTTTTTGA GGTGGCACAG 
ATCCACTCTC TGTCCTTCAA GGCCATCAGC AGTGCCATGG GTCTTGGCTT CCTGCTCTCC 
TTGCTTTTCT TCATTGAGCA GAACCTGGTG GCCGCCCTGG TCAATGCACC AGAGAACAGG 
CTGGTGAAGG GCACTGCCTA TCACTGGGAC CTCCTGCTGC TTGCCATCAT CAATACGGGG 
CTGTCTCTGT TTGGGCTACC CTGGATCCAC GCCGCCTATC CCCATTCCCC TCTGCATGTG 
CGGGCACTGG CCTTAGTGGA GGAACGTGTG GAGAATGGGC ACATTTATGA AACGATTGTG 
AATGTTAAGG AGACTCGGCT GACTGCGCTG GGTGCCAGTG TCCTGGTGGG TCTGTCCCTG 
CTGCTGCTTC CATTCCCGCT GCAGTGGATC CCCAAGCCCG TGCTCTATGG ACTCTTCCTC 
TACATTGCGC TGACCTCCCT GGACGGCAAC CAGCTCTTCT CACGTGTAGC TCTGCTGCTC 
AAGGAGCAAA CGTCATACCC ACCCACACAC TACATCCGGA GAGTGCCCCA AAGGAAGATT 
CACTACTTCA CGGGCCTGCA GATTCTGCAG CTGCTTCTGC TCTGTGCGTT CGGCATGAGC 
TCCCTGCCCT ACATGAAGAT GGTCTTTCCG CTCATCATGA TTGCCATGAT CCCAATCCGC 
TATAATCTGC TACCCCGAAT CATTGAAGCC AAGTACTTGG ATGTCATGGA TGCCGAGCAC 
AGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101245.1
CDS	134..2722
Translation	MSQNEHCQDSGEYFSAATLGYFKNDTDDNPDVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDIEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFAQDPNHAEPDCDLDLLMAKLFTDAGGPMESKVHLLSDTIQGVTATVRGLQYEQSWLCIVCTMKSLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPRPPKCKDFFPFGKGIWVDIMRRFPVYPLDFTDGIIGKGKTVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFWKYYYGHHYHTKRTSSLASLLGISRSPNTSLHTALNTSFLASPIEMTTASSPISTHSNQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLISSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAISSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVNVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP

Target ORF information:

RefSeq Version	NM_001107775.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 11 (Slc4a11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107775.1

ORF Insert Sequence:

ATGTCACAGA ATGAACACTG TCAGGACTCC GGTGAATACT TCTCAGCCGC CACTCTGGGA 
TACTTCAAGA ATGACACAGA TGATAACCCT GACGTCCGGG AGGACAGCCT GGGGGATGAG 
GTCTTTGACA CCGTCAACTC CTCCATTGTG TCTGGCGAGA GCATCCGTTT TTTTGTCAAT 
GTCAACCTTG AAGTGCAGCC TTCCAAATCT GACATAGAAG CTGCAACTGG AGGCTGCGTG 
CTCTTACACA CCTCCCGCAA GTATCTGAAA TTAAAGAACT TCGAGGAAGA GGTCCGTGCA 
CACCGTGACC TGGATGGCTT CCTGGCCCAG GCCAGCATCA TCCTGAATGA GACAGCTACC 
TCACTGGATG ATGTGCTCCG AACTATGCTA AACCGCTTTG CCCAGGACCC CAACCATGCA 
GAGCCTGATT GTGACCTGGA CCTGCTCATG GCTAAGCTCT TTACAGATGC TGGGGGCCCC 
ATGGAGAGTA AAGTCCACCT GCTGTCAGAT ACCATCCAGG GAGTGACCGC CACTGTCAGA 
GGACTGCAGT ACGAGCAGTC ATGGCTCTGC ATCGTCTGTA CCATGAAGTC CCTACAGAAG 
CGGCATGTGT GTATCAGCCG CCTGGTTCGG CCACAGAACT GGGGGGAAAA CTCCTGTGAG 
GTTCGCTTTG TCATCCTGGT GCTGGCCCCA CCCAAGATGA AAAGCACCAA GACTGCGATG 
GAGGTGGCAC GCACATTCGC CACCATGTTC TCCGACATCA CCTTCCGCCA GAAGCTCCTG 
AAGACCCGCA CAGAGGAAGA GTTCAAGGAG GCTTTGGTGC ACCAGAGACA GCTGCTCACC 
ATGATGATGC CAAGAGCAGC CGGGCACAGC ATGAGCTCCC TCCATACTCA CAGACACCCT 
CGGCCCCCGA AATGCAAGGA CTTTTTCCCG TTTGGGAAAG GCATCTGGGT GGACATCATG 
CGCAGGTTCC CTGTGTACCC GCTGGACTTC ACGGACGGCA TCATTGGGAA AGGCAAGACT 
GTCGGCAAAT ATGTCACCAC CACGCTCTTC CTCTACTTCG CCTGCCTCTT ACCGACCATT 
GCTTTTGGAT CCCTCAACGA TGAGAACACA AACGGAGCCA TCGATGTGCA GAAGACCATA 
GCAGGACAGA GCATCGGAGG CCTCTTGTAT GCACTGTTCT CTGGGCAGCC CCTGGTGATC 
CTGTTGACAA CCGCACCCCT GGCCATCTAC ACCCAGGTGA TCCGGGTCAT CTGTGATGAC 
TACAACCTGG ACTTCAACGC CTTCTATGCG TGGACAGGCC TGTGGAACAG CTTCTTCCTT 
GCGCTTTATG CCTTCCTCAA CCTCAGCCTG CTTATGAATC TCTTTAAGAG GTCAACAGAG 
GAGATCATTG CTCTGTTCAT TTCCATCACG TTTGTGCTGG ACGCTGTCAA GGGCATGGTC 
AAAATCTTCT GGAAGTACTA CTATGGTCAC CACTACCACA CAAAAAGGAC TTCCTCCTTG 
GCAAGCCTGT TGGGCATTAG CAGAAGCCCC AACACCAGTC TCCACACTGC ACTCAACACC 
AGCTTCTTGG CCAGCCCCAT AGAGATGACT ACAGCCAGCA GCCCCATCAG TACACACTCC 
AACCAGGCTA CTGCAGTGCT CAGCCTCCTC ATCATGCTGG GCACACTCTG GCTGGGCTAC 
ACCCTCTACC AGTTCAAGAA AAGCCCCTAC CTGCACCCAT GTGTGCGTGA GACCCTGTCT 
GACTGTGCCC TGCCTATCGC CGTGCTCTCC TTCTCCCTCA TCAGCTCCTA TGGCTTCCAG 
GAAATTGAGA TGAGCAAGTT CCGGTACAAC CCCAGCGAGA GCCTTTTTGA GGTGGCACAG 
ATCCACTCTC TGTCCTTCAA GGCCATCAGC AGTGCCATGG GTCTTGGCTT CCTGCTCTCC 
TTGCTTTTCT TCATTGAGCA GAACCTGGTG GCCGCCCTGG TCAATGCACC AGAGAACAGG 
CTGGTGAAGG GCACTGCCTA TCACTGGGAC CTCCTGCTGC TTGCCATCAT CAATACGGGG 
CTGTCTCTGT TTGGGCTACC CTGGATCCAC GCCGCCTATC CCCATTCCCC TCTGCATGTG 
CGGGCACTGG CCTTAGTGGA GGAACGTGTG GAGAATGGGC ACATTTATGA AACGATTGTG 
AATGTTAAGG AGACTCGGCT GACTGCGCTG GGTGCCAGTG TCCTGGTGGG TCTGTCCCTG 
CTGCTGCTTC CATTCCCGCT GCAGTGGATC CCCAAGCCCG TGCTCTATGG ACTCTTCCTC 
TACATTGCGC TGACCTCCCT GGACGGCAAC CAGCTCTTCT CACGTGTAGC TCTGCTGCTC 
AAGGAGCAAA CGTCATACCC ACCCACACAC TACATCCGGA GAGTGCCCCA AAGGAAGATT 
CACTACTTCA CGGGCCTGCA GATTCTGCAG CTGCTTCTGC TCTGTGCGTT CGGCATGAGC 
TCCCTGCCCT ACATGAAGAT GGTCTTTCCG CTCATCATGA TTGCCATGAT CCCAATCCGC 
TATAATCTGC TACCCCGAAT CATTGAAGCC AAGTACTTGG ATGTCATGGA TGCCGAGCAC 
AGGCCCTGA