Eif5a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif5a2
Entrez Gene ID	310261
Full Name	eukaryotic translation initiation factor 5A2
Synonyms	eIF5AII
General protein information	Preferred Names eukaryotic translation initiation factor 5A2 Names eukaryotic translation initiation factor 5A-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100697.2	NP_001094167.1	eukaryotic translation initiation factor 5A-2
XM_006232231.3	XP_006232293.1	eukaryotic translation initiation factor 5A-2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Eif5a2	NP_001094167.1
Pan troglodytes (chimpanzee)	EIF5A2	XP_001163733.1
Bos taurus (cattle)	EIF5A2	NP_001179018.1
Gallus gallus (chicken)	EIF5A2	NP_990863.1
Homo sapiens (human)	EIF5A2	NP_065123.1
	EIF5A2	XP_002802971.1
Canis lupus familiaris (dog)	EIF5A2	XP_005639970.1
Mus musculus (house mouse)	Eif5a2	NP_808254.1

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability.
Chen M, Huang JD, Deng HK, Dong S, Deng W, Tsang SL, Huen MS, Chen L, Zan T, Zhu GX, Guan XY
BMC cancer11199(2011 May)

Identification and characterization of eukaryotic initiation factor 5A-2.
Clement PM, Henderson CA, Jenkins ZA, Smit-McBride Z, Wolff EC, Hershey JW, Park MH, Johansson HE
European journal of biochemistry270(21)4254-63(2003 Nov)

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.
Jenkins ZA, H??g PG, Johansson HE
Genomics71(1)101-9(2001 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif5a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif5a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05508	NM_001100697.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa05508	XM_006232231.3 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif5a2 ( NM_001100697.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094167.1 Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), mRNA.

Price & Availability↑

CloneID	ORa05508
Clone ID Related Accession (Same CDS sequence)	NM_001100697.2 , XM_006232231.3
Accession Version	NM_001100697.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 5A-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07009894.1. On Jul 7, 2012 this sequence version replaced NM_001100697.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FM039313.1, CB720229.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGACG AAATTGATTT CACTACTGGA GATGCAGGGG CTTCCAGCAC TTATCCTATG 
CAGTGCTCAG CCCTGCGCAA AAACGGCTTC GTGGTGCTCA AAGGGCGTCC ATGCAAAATC 
GTGGAGATGT CAACTTCCAA GACTGGGAAG CATGGTCATG CCAAGGTACA CCTTGTTGGA 
ATTGACATTT TCACTGGCAA AAAATATGAA GATATTTGTC CTTCCACTCA CAACATGGAT 
GTTCCAAACA TTAAGAGAAA TGATTATCAA CTCATATGCA TTCAGGATGG TTACCTTTCC 
CTGCTGACAG AAACTGGCGA AGTCCGTGAG GATCTCAAGC TGCCAGAAGG TGAACTGGGC 
AAAGAAATCG AAGGGAAGTA CAATGCAGGT GAAGATGTGC AGGTGTCCGT CATGTGCGCC 
ATGAGTGAAG AATACGCTGT AGCCATAAAG CCCTGCAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094167.1
CDS	120..581
Translation	MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK

Target ORF information:

RefSeq Version	NM_001100697.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100697.2

ORF Insert Sequence:

ATGGCAGACG AAATTGATTT CACTACTGGA GATGCAGGGG CTTCCAGCAC TTATCCTATG 
CAGTGCTCAG CCCTGCGCAA AAACGGCTTC GTGGTGCTCA AAGGGCGTCC ATGCAAAATC 
GTGGAGATGT CAACTTCCAA GACTGGGAAG CATGGTCATG CCAAGGTACA CCTTGTTGGA 
ATTGACATTT TCACTGGCAA AAAATATGAA GATATTTGTC CTTCCACTCA CAACATGGAT 
GTTCCAAACA TTAAGAGAAA TGATTATCAA CTCATATGCA TTCAGGATGG TTACCTTTCC 
CTGCTGACAG AAACTGGCGA AGTCCGTGAG GATCTCAAGC TGCCAGAAGG TGAACTGGGC 
AAAGAAATCG AAGGGAAGTA CAATGCAGGT GAAGATGTGC AGGTGTCCGT CATGTGCGCC 
ATGAGTGAAG AATACGCTGT AGCCATAAAG CCCTGCAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif5a2 ( XM_006232231.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232293.1 Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05508
Clone ID Related Accession (Same CDS sequence)	NM_001100697.2 , XM_006232231.3
Accession Version	XM_006232231.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 5A-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232231.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGACG AAATTGATTT CACTACTGGA GATGCAGGGG CTTCCAGCAC TTATCCTATG 
CAGTGCTCAG CCCTGCGCAA AAACGGCTTC GTGGTGCTCA AAGGGCGTCC ATGCAAAATC 
GTGGAGATGT CAACTTCCAA GACTGGGAAG CATGGTCATG CCAAGGTACA CCTTGTTGGA 
ATTGACATTT TCACTGGCAA AAAATATGAA GATATTTGTC CTTCCACTCA CAACATGGAT 
GTTCCAAACA TTAAGAGAAA TGATTATCAA CTCATATGCA TTCAGGATGG TTACCTTTCC 
CTGCTGACAG AAACTGGCGA AGTCCGTGAG GATCTCAAGC TGCCAGAAGG TGAACTGGGC 
AAAGAAATCG AAGGGAAGTA CAATGCAGGT GAAGATGTGC AGGTGTCCGT CATGTGCGCC 
ATGAGTGAAG AATACGCTGT AGCCATAAAG CCCTGCAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232293.1
CDS	883..1344
Translation	MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK

Target ORF information:

RefSeq Version	XM_006232231.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 5A2 (Eif5a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232231.3

ORF Insert Sequence:

ATGGCAGACG AAATTGATTT CACTACTGGA GATGCAGGGG CTTCCAGCAC TTATCCTATG 
CAGTGCTCAG CCCTGCGCAA AAACGGCTTC GTGGTGCTCA AAGGGCGTCC ATGCAAAATC 
GTGGAGATGT CAACTTCCAA GACTGGGAAG CATGGTCATG CCAAGGTACA CCTTGTTGGA 
ATTGACATTT TCACTGGCAA AAAATATGAA GATATTTGTC CTTCCACTCA CAACATGGAT 
GTTCCAAACA TTAAGAGAAA TGATTATCAA CTCATATGCA TTCAGGATGG TTACCTTTCC 
CTGCTGACAG AAACTGGCGA AGTCCGTGAG GATCTCAAGC TGCCAGAAGG TGAACTGGGC 
AAAGAAATCG AAGGGAAGTA CAATGCAGGT GAAGATGTGC AGGTGTCCGT CATGTGCGCC 
ATGAGTGAAG AATACGCTGT AGCCATAAAG CCCTGCAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability.
BMC cancer11199(2011 May)
Chen M,Huang JD,Deng HK,Dong S,Deng W,Tsang SL,Huen MS,Chen L,Zan T,Zhu GX,Guan XY

Identification and characterization of eukaryotic initiation factor 5A-2.
European journal of biochemistry270(21)4254-63(2003 Nov)
Clement PM,Henderson CA,Jenkins ZA,Smit-McBride Z,Wolff EC,Hershey JW,Park MH,Johansson HE

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.
Genomics71(1)101-9(2001 Jan)
Jenkins ZA,H??g PG,Johansson HE