Ap3b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ap3b1
Entrez Gene ID	309969
Full Name	adaptor-related protein complex 3, beta 1 subunit
General protein information	Preferred Names adaptor-related protein complex 3, beta 1 subunit Names AP-3 complex subunit beta-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107646.1	NP_001101116.1	AP-3 complex subunit beta-1
XM_006231814.3	XP_006231876.1	AP-3 complex subunit beta-1 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC563316	XP_691776.5
Rattus norvegicus (Norway rat)	Ap3b1	NP_001101116.1

Gene Ontology
Bibliography

Related articles in PubMed

BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.
Bultema JJ, Ambrosio AL, Burek CL, Di Pietro SM
The Journal of biological chemistry287(23)19550-63(2012 Jun)

Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease.
Gochuico BR, Huizing M, Golas GA, Scher CD, Tsokos M, Denver SD, Frei-Jones MJ, Gahl WA
Molecular medicine (Cambridge, Mass.)1856-64(2012 Feb)

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Larimore J, Tornieri K, Ryder PV, Gokhale A, Zlatic SA, Craige B, Lee JD, Talbot K, Pare JF, Smith Y, Faundez V
Molecular biology of the cell22(24)4854-67(2011 Dec)

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, Livstone MS, Lewis SE, Thomas PD
Briefings in bioinformatics12(5)449-62(2011 Sep)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ap3b1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ap3b1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41423	NM_001107646.1 Latest version!	Rattus norvegicus adaptor related protein complex 3 subunit beta 1 (Ap3b1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$468.30 $669.00
ORa24331	XM_006231814.3 Latest version!	Rattus norvegicus adaptor-related protein complex 3, beta 1 subunit (Ap3b1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ap3b1 ( NM_001107646.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101116.1 Rattus norvegicus adaptor related protein complex 3 subunit beta 1 (Ap3b1), mRNA.

Price & Availability↑

CloneID	ORa41423
Clone ID Related Accession (Same CDS sequence)	NM_001107646.1
Accession Version	NM_001107646.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	AP-3 complex subunit beta-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473955.1. On or before Oct 4, 2007 this sequence version replaced XM_226666.4, XM_001067082.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGCTGTCG CTCAGCTGTA CTGGCACATC TCACCCAGGT CGGAGGCTGG TGTCATTTCT 
AAATCGCTGG TGCGCCTACT TCGCAGCCAT AGGGAGGTGC AGTATATTGT ATTGCAAAAT 
ATCGCAACTA TGTCAATTCA GAGAAAGGGT ATGTTTGAAC CTTACCTGAA GAGCTTCTAT 
GTCCGGTCCA CTGATCCAAC TATGATCAAG ACTCTGAAGC TTGAAATCTT GACAAACTTG 
GCAAATGAAG CCAACATATC AACTCTTCTT CGAGAATTTC AGACCTACGT GAGAAGCCAG 
GACAAACAGT TTGCAGCGGC CACTATTCAG ACCATAGGCA GATGTGCAAC CAGCATTGCC 
GAGGTCACTG ACACATGCCT CAATGGCCTG GTCTGCCTGC TGTCCAACAG GGATGAAATA 
GTTGTTGCTG AAAGTGTGGT TGTTATAAAG AAATTGTTGC AAATGCAGCC TGCACAGCAT 
GGTGAGATTA TTAAGCACAT GGCGAAGCTG TTGGACAGCA TCACTGTCCC TGTGGCTCGA 
GCAAGCATTC TTTGGCTGAT TGGAGAAAAC TGTGAACGCG TTCCTAAAAT TGCTCCTGAT 
GTTTTGAGAA AAATGGCTAA AAGTTTCACT AGTGAAGATG ATCTGGTGAA ACTGCAGATT 
TTAAATCTTG GAGCAAAATT GTATTTAACT AATTCCAAAC AGACAAAATT GCTTACCCAG 
TACATATTAA ATCTCGGCAA GTATGATCAG AACTACGACA TCAGAGACCG CACAAGATTT 
ATTAGGCAGC TTATTGTTCC GAACGAGAAG AGTGGAGCTC TAAGTAAATA TGCCAAAAAA 
ATCTTTCTAG CACAGAAGCC TGCACCACTG CTGGAGTCTC CCTTTAAAGA CAGGGATCAT 
TTCCAGCTTG GCACCTTATC TCATACTCTC AACGTTAAAG CGTCCGGGTA CCTGGAATTA 
TCTAATTGGC CAGAGGTGGC GCCTGACCCA TCGGTTCGCA ATGTAGAAGT AATAGAGTCA 
GCAAAAGAGT GGACCCCACT TGGAAAAACA AAGAAAGAAA AACCTGAGAA GAAATTTTAT 
TCAGAATCTG AGGAGGAGGA GGAGGAAGAA GAGGAAGATG AAGAAGATGA GGAGGAGGAT 
CCCTCTGATA GCAGCAGTGA CAGTGAGAGT GGGTCTGGAC GTGAGAGTGG AGACTCAGGC 
AGCAGCAGCG AGGACAGCAG CGAGGACTCC TCCAGTGGAC AAGACAGCGA GACCGGAAGC 
GAGGCAGAAG CAGAACACCA GAGGGTGGCC AAGACGAACT CCAAAACCAA GAGGAAAAGT 
GCCTCAGAAG ACAGGGAGAA GAAAAATGGA AAATCTCAGG CCTCGGAGTC GTCCAGTGAG 
GAGTCCAGTT CCACAGAAGA AAGTTCTTCA GAGTCAGAGT CAGGCTCTGA CAGTGAGCCT 
GCACCCAGAA AAACAGCTAA GGCAAAAGAA AGAAAACCCC AGCAAGAAAG ACATCCTCCC 
TCCAAAGATG TTTTCCTTCT CGATCTGGAT GACTTTAACC CAGTATCCAC CCCAGTTGCC 
CTTCCTACAC CAGCCCTTTC TCCAAGCTTG ATAGCTGATC TTGAAGGTCT AAACCTGTCA 
ACTTCCTCAT CCATCATCAA CGTCAGTACA CCTGTCTTCG TGCCCACAAA AACACATGAG 
CTGCTTCACC GCATGCGTGG GAAAGGACTG GCTGCCCACT ACTGCTTCCC AAGACAGCCT 
TGCATCTTCG GTGACAAGAT GGTCTCTGTA CAGATAACCC TGACCAATAC TTCCGATGGG 
AAGATAGAGA ACATCCACGT AGGCGGGAAG AAGCTTGCTG TGGGCGTGCA GATGCACGTC 
TTCCATCCCA TAGAGTCTCT GGAGCCTGAG GGATCCGTTA CTGTCTCGAT GGGTATTGAC 
TTCTGTGATT CTACACAGAC GGCCAGTTTT CAGCTGTGCA CCAAGGATGA TTGCTTCAAC 
GTCAACATCC AGCCACCTGT TGGGGAGCTG CTTTTACCTG TGGCCATGTC AGAGAAAGAC 
TTTAAGAAGG AGCAAGGGAT GCTCACTGGG ATGAATGAGA CGTCGGCAAC GCTCATCGCC 
GCTCCGCAGA ACTTCACCCC CTCCATGATC CTCCAGAAGG TTGTAAACGT CGCCAACCTC 
GGTGCAGTGC CTTCCAGCCA AGATAACATA CACAGATATG AGAGATTAAA ATTCCAAGTT 
CTTCAAGAAA GGTTTGCAGC TAAAACTGTG CACAGTGGGT CACTGATGCT AGTCACCGTG 
GAACTGAAGG AAGGTTCCAC AGCCCAACTT ATCATCAACA CCGAGAAAAC CGTGATTGGC 
TCTGTGCTGC TGAGGGAGCT GAAGCCTGTC CTGTCCCAGG GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101116.1
CDS	764..3148
Translation	MAVAQLYWHISPRSEAGVISKSLVRLLRSHREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDKQFAAATIQTIGRCATSIAEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNVKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPLGKTKKEKPEKKFYSESEEEEEEEEEDEEDEEEDPSDSSSDSESGSGRESGDSGSSSEDSSEDSSSGQDSETGSEAEAEHQRVAKTNSKTKRKSASEDREKKNGKSQASESSSEESSSTEESSSESESGSDSEPAPRKTAKAKERKPQQERHPPSKDVFLLDLDDFNPVSTPVALPTPALSPSLIADLEGLNLSTSSSIINVSTPVFVPTKTHELLHRMRGKGLAAHYCFPRQPCIFGDKMVSVQITLTNTSDGKIENIHVGGKKLAVGVQMHVFHPIESLEPEGSVTVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQGMLTGMNETSATLIAAPQNFTPSMILQKVVNVANLGAVPSSQDNIHRYERLKFQVLQERFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG

Target ORF information:

RefSeq Version	NM_001107646.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adaptor related protein complex 3 subunit beta 1 (Ap3b1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107646.1

ORF Insert Sequence:

ATGGCTGTCG CTCAGCTGTA CTGGCACATC TCACCCAGGT CGGAGGCTGG TGTCATTTCT 
AAATCGCTGG TGCGCCTACT TCGCAGCCAT AGGGAGGTGC AGTATATTGT ATTGCAAAAT 
ATCGCAACTA TGTCAATTCA GAGAAAGGGT ATGTTTGAAC CTTACCTGAA GAGCTTCTAT 
GTCCGGTCCA CTGATCCAAC TATGATCAAG ACTCTGAAGC TTGAAATCTT GACAAACTTG 
GCAAATGAAG CCAACATATC AACTCTTCTT CGAGAATTTC AGACCTACGT GAGAAGCCAG 
GACAAACAGT TTGCAGCGGC CACTATTCAG ACCATAGGCA GATGTGCAAC CAGCATTGCC 
GAGGTCACTG ACACATGCCT CAATGGCCTG GTCTGCCTGC TGTCCAACAG GGATGAAATA 
GTTGTTGCTG AAAGTGTGGT TGTTATAAAG AAATTGTTGC AAATGCAGCC TGCACAGCAT 
GGTGAGATTA TTAAGCACAT GGCGAAGCTG TTGGACAGCA TCACTGTCCC TGTGGCTCGA 
GCAAGCATTC TTTGGCTGAT TGGAGAAAAC TGTGAACGCG TTCCTAAAAT TGCTCCTGAT 
GTTTTGAGAA AAATGGCTAA AAGTTTCACT AGTGAAGATG ATCTGGTGAA ACTGCAGATT 
TTAAATCTTG GAGCAAAATT GTATTTAACT AATTCCAAAC AGACAAAATT GCTTACCCAG 
TACATATTAA ATCTCGGCAA GTATGATCAG AACTACGACA TCAGAGACCG CACAAGATTT 
ATTAGGCAGC TTATTGTTCC GAACGAGAAG AGTGGAGCTC TAAGTAAATA TGCCAAAAAA 
ATCTTTCTAG CACAGAAGCC TGCACCACTG CTGGAGTCTC CCTTTAAAGA CAGGGATCAT 
TTCCAGCTTG GCACCTTATC TCATACTCTC AACGTTAAAG CGTCCGGGTA CCTGGAATTA 
TCTAATTGGC CAGAGGTGGC GCCTGACCCA TCGGTTCGCA ATGTAGAAGT AATAGAGTCA 
GCAAAAGAGT GGACCCCACT TGGAAAAACA AAGAAAGAAA AACCTGAGAA GAAATTTTAT 
TCAGAATCTG AGGAGGAGGA GGAGGAAGAA GAGGAAGATG AAGAAGATGA GGAGGAGGAT 
CCCTCTGATA GCAGCAGTGA CAGTGAGAGT GGGTCTGGAC GTGAGAGTGG AGACTCAGGC 
AGCAGCAGCG AGGACAGCAG CGAGGACTCC TCCAGTGGAC AAGACAGCGA GACCGGAAGC 
GAGGCAGAAG CAGAACACCA GAGGGTGGCC AAGACGAACT CCAAAACCAA GAGGAAAAGT 
GCCTCAGAAG ACAGGGAGAA GAAAAATGGA AAATCTCAGG CCTCGGAGTC GTCCAGTGAG 
GAGTCCAGTT CCACAGAAGA AAGTTCTTCA GAGTCAGAGT CAGGCTCTGA CAGTGAGCCT 
GCACCCAGAA AAACAGCTAA GGCAAAAGAA AGAAAACCCC AGCAAGAAAG ACATCCTCCC 
TCCAAAGATG TTTTCCTTCT CGATCTGGAT GACTTTAACC CAGTATCCAC CCCAGTTGCC 
CTTCCTACAC CAGCCCTTTC TCCAAGCTTG ATAGCTGATC TTGAAGGTCT AAACCTGTCA 
ACTTCCTCAT CCATCATCAA CGTCAGTACA CCTGTCTTCG TGCCCACAAA AACACATGAG 
CTGCTTCACC GCATGCGTGG GAAAGGACTG GCTGCCCACT ACTGCTTCCC AAGACAGCCT 
TGCATCTTCG GTGACAAGAT GGTCTCTGTA CAGATAACCC TGACCAATAC TTCCGATGGG 
AAGATAGAGA ACATCCACGT AGGCGGGAAG AAGCTTGCTG TGGGCGTGCA GATGCACGTC 
TTCCATCCCA TAGAGTCTCT GGAGCCTGAG GGATCCGTTA CTGTCTCGAT GGGTATTGAC 
TTCTGTGATT CTACACAGAC GGCCAGTTTT CAGCTGTGCA CCAAGGATGA TTGCTTCAAC 
GTCAACATCC AGCCACCTGT TGGGGAGCTG CTTTTACCTG TGGCCATGTC AGAGAAAGAC 
TTTAAGAAGG AGCAAGGGAT GCTCACTGGG ATGAATGAGA CGTCGGCAAC GCTCATCGCC 
GCTCCGCAGA ACTTCACCCC CTCCATGATC CTCCAGAAGG TTGTAAACGT CGCCAACCTC 
GGTGCAGTGC CTTCCAGCCA AGATAACATA CACAGATATG AGAGATTAAA ATTCCAAGTT 
CTTCAAGAAA GGTTTGCAGC TAAAACTGTG CACAGTGGGT CACTGATGCT AGTCACCGTG 
GAACTGAAGG AAGGTTCCAC AGCCCAACTT ATCATCAACA CCGAGAAAAC CGTGATTGGC 
TCTGTGCTGC TGAGGGAGCT GAAGCCTGTC CTGTCCCAGG GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ap3b1 ( XM_006231814.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231876.1 Rattus norvegicus adaptor-related protein complex 3, beta 1 subunit (Ap3b1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24331
Clone ID Related Accession (Same CDS sequence)	XM_006231814.3
Accession Version	XM_006231814.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3291bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	AP-3 complex subunit beta-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231814.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTAGCA ACAGTTTCGC CTACAACGAG CAGTCCGGAG GAGGGGAGGC GGCGGAGCTG 
GGGCAGGAGG CCACCTCGAC CATCTCTTCC TCGGGCGCCT TCGGCCTCTT CAGCAGCGAT 
TGGAAGAAGA ATGAAGACCT GAAGCAGATG CTGGAGAGCA ACAAAGATTC TGCCAAACTG 
GATGCTATGA AGCGGATTGT TGGGATGATT GCAAAGGGGA AAAATGCCTC AGAACTCTTC 
CCTGCTGTTG TGAAGAATGT GGCCAGTAAA AACATCGAGA TCAAGAAGCT GGTGTATGTT 
TACCTCGTCC GATACGCTGA GGAACAGCAG GACTTGGCTC TCCTGTCCAT AAGCACTTTC 
CAGCGTGCTT TGAAGGACCC AAATCAACTA ATCCGCGCAA GTGCCTTGAG AGTTTTGTCA 
AGTATTAGAG TGCCGATTAT CGTGCCTGTC ATGATGCTGG CTATCAAGGA GGCATCAGCT 
GACCTGTCGC CCTATGTTAG GAAGAATGCA GCCCATGCTA TCCAGAAGCT GTACAGTCTT 
GACCCTGAGC AGAAGGAGAT GCTGATTGAG GTCATCGAGA AACTCCTGAA GGATAAGAGC 
ACGCTGGTGG CTGGCAGTGT GGTGATGGCT TTTGAAGAGG TGTGCCCAGA TCGAATCGAT 
CTGATCCACA GGAATTACCG CAAGCTTTGT AACCTACTGG TTGATGTTGA AGAGTGGGGG 
CAGGTGGTCA TAATCCATAT GCTAACACGA TACGCTCGGA CCCAGTTCGT TAGTCCTTGG 
AGAGAGGATG ATGGTGTAGA AGACAATGAA AAGAATTTCT ATGATTCTGA CGATGAGGAG 
AAGAAGAGTG GCAAGAAGAA ACCGTACAGC ATGGATCCGG ACCACAGACT CTTAATCAGA 
AACACAAAGC CCTTACTTCA GAGCAGGAAC GCAGCGGTGG TTATGGCTGT CGCTCAGCTG 
TACTGGCACA TCTCACCCAG GTCGGAGGCT GGTGTCATTT CTAAATCGCT GGTGCGCCTA 
CTTCGCAGCC ATAGGGAGGT GCAGTATATT GTATTGCAAA ATATCGCAAC TATGTCAATT 
CAGAGAAAGG GTATGTTTGA ACCTTACCTG AAGAGCTTCT ATGTCCGGTC CACTGATCCA 
ACTATGATCA AGACTCTGAA GCTTGAAATC TTGACAAACT TGGCAAATGA AGCCAACATA 
TCAACTCTTC TTCGAGAATT TCAGACCTAC GTGAGAAGCC AGGACAAACA GTTTGCAGCG 
GCCACTATTC AGACCATAGG CAGATGTGCA ACCAGCATTG CCGAGGTCAC TGACACATGC 
CTCAATGGCC TGGTCTGCCT GCTGTCCAAC AGGGATGAAA TAGTTGTTGC TGAAAGTGTG 
GTTGTTATAA AGAAATTGTT GCAAATGCAG CCTGCACAGC ATGGTGAGAT TATTAAGCAC 
ATGGCGAAGC TGTTGGACAG CATCACTGTC CCTGTGGCTC GAGCAAGCAT TCTTTGGCTG 
ATTGGAGAAA ACTGTGAACG CGTTCCTAAA ATTGCTCCTG ATGTTTTGAG AAAAATGGCT 
AAAAGTTTCA CTAGTGAAGA TGATCTGGTG AAACTGCAGA TTTTAAATCT TGGAGCAAAA 
TTGTATTTAA CTAATTCCAA ACAGACAAAA TTGCTTACCC AGTACATATT AAATCTCGGC 
AAGTATGATC AGAACTACGA CATCAGAGAC CGCACAAGAT TTATTAGGCA GCTTATTGTT 
CCGAACGAGA AGAGTGGAGC TCTAAGTAAA TATGCCAAAA AAATCTTTCT AGCACAGAAG 
CCTGCACCAC TGCTGGAGTC TCCCTTTAAA GACAGGGATC ATTTCCAGCT TGGCACCTTA 
TCTCATACTC TCAACGTTAA AGCGTCCGGG TACCTGGAAT TATCTAATTG GCCAGAGGTG 
GCGCCTGACC CATCGGTTCG CAATGTAGAA GTAATAGAGT CAGCAAAAGA GTGGACCCCA 
CTTGGAAAAA CAAAGAAAGA AAAACCTGAG AAGAAATTTT ATTCAGAATC TGAGGAGGAG 
GAGGAGGAAG AAGAGGAAGA TGAAGAAGAT GAGGAGGAGG ATCCCTCTGA TAGCAGCAGT 
GACAGTGAGA GTGGGTCTGG ACGTGAGAGT GGAGACTCAG GCAGCAGCAG CGAGGACAGC 
AGCGAGGACT CCTCCAGTGG ACAAGACAGC GAGACCGGAA GCGAGGCAGA AGCAGAACAC 
CAGAGGGTGG CCAAGACGAA CTCCAAAACC AAGAGGAAAA GTGCCTCAGA AGACAGGGAG 
AAGAAAAATG GAAAATCTCA GGCCTCGGAG TCGTCCAGTG AGGAGTCCAG TTCCACAGAA 
GAAAGTTCTT CAGAGTCAGA GTCAGGCTCT GACAGTGAGC CTGCACCCAG AAAAACAGCT 
AAGGCAAAAG AAAGAAAACC CCAGCAAGAA AGACATCCTC CCTCCAAAGA TGTTTTCCTT 
CTCGATCTGG ATGACTTTAA CCCAGTATCC ACCCCAGTTG CCCTTCCTAC ACCAGCCCTT 
TCTCCAAGCT TGATAGCTGA TCTTGAAGGT CTAAACCTGT CAACTTCCTC ATCCATCATC 
AACGTCAGTA CACCTGTCTT CGTGCCCACA AAAACACATG AGCTGCTTCA CCGCATGCGT 
GGGAAAGGAC TGGCTGCCCA CTACTGCTTC CCAAGACAGC CTTGCATCTT CGGTGACAAG 
ATGGTCTCTG TACAGATAAC CCTGACCAAT ACTTCCGATG GGAAGATAGA GAACATCCAC 
GTAGGCGGGA AGAAGCTTGC TGTGGGCGTG CAGATGCACG TCTTCCATCC CATAGAGTCT 
CTGGAGCCTG AGGGATCCGT TACTGTCTCG ATGGGTATTG ACTTCTGTGA TTCTACACAG 
ACGGCCAGTT TTCAGCTGTG CACCAAGGAT GATTGCTTCA ACGTCAACAT CCAGCCACCT 
GTTGGGGAGC TGCTTTTACC TGTGGCCATG TCAGAGAAAG ACTTTAAGAA GGAGCAAGGG 
ATGCTCACTG GGATGAATGA GACGTCGGCA ACGCTCATCG CCGCTCCGCA GAACTTCACC 
CCCTCCATGA TCCTCCAGAA GGTTGTAAAC GTCGCCAACC TCGGTGCAGT GCCTTCCAGC 
CAAGATAACA TACACAGGTT TGCAGCTAAA ACTGTGCACA GTGGGTCACT GATGCTAGTC 
ACCGTGGAAC TGAAGGAAGG TTCCACAGCC CAACTTATCA TCAACACCGA GAAAACCGTG 
ATTGGCTCTG TGCTGCTGAG GGAGCTGAAG CCTGTCCTGT CCCAGGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231876.1
CDS	2092..5382
Translation	MSSNSFAYNEQSGGGEAAELGQEATSTISSSGAFGLFSSDWKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPVMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWREDDGVEDNEKNFYDSDDEEKKSGKKKPYSMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPRSEAGVISKSLVRLLRSHREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDKQFAAATIQTIGRCATSIAEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNVKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPLGKTKKEKPEKKFYSESEEEEEEEEEDEEDEEEDPSDSSSDSESGSGRESGDSGSSSEDSSEDSSSGQDSETGSEAEAEHQRVAKTNSKTKRKSASEDREKKNGKSQASESSSEESSSTEESSSESESGSDSEPAPRKTAKAKERKPQQERHPPSKDVFLLDLDDFNPVSTPVALPTPALSPSLIADLEGLNLSTSSSIINVSTPVFVPTKTHELLHRMRGKGLAAHYCFPRQPCIFGDKMVSVQITLTNTSDGKIENIHVGGKKLAVGVQMHVFHPIESLEPEGSVTVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQGMLTGMNETSATLIAAPQNFTPSMILQKVVNVANLGAVPSSQDNIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG

Target ORF information:

RefSeq Version	XM_006231814.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adaptor-related protein complex 3, beta 1 subunit (Ap3b1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231814.3

ORF Insert Sequence:

ATGTCTAGCA ACAGTTTCGC CTACAACGAG CAGTCCGGAG GAGGGGAGGC GGCGGAGCTG 
GGGCAGGAGG CCACCTCGAC CATCTCTTCC TCGGGCGCCT TCGGCCTCTT CAGCAGCGAT 
TGGAAGAAGA ATGAAGACCT GAAGCAGATG CTGGAGAGCA ACAAAGATTC TGCCAAACTG 
GATGCTATGA AGCGGATTGT TGGGATGATT GCAAAGGGGA AAAATGCCTC AGAACTCTTC 
CCTGCTGTTG TGAAGAATGT GGCCAGTAAA AACATCGAGA TCAAGAAGCT GGTGTATGTT 
TACCTCGTCC GATACGCTGA GGAACAGCAG GACTTGGCTC TCCTGTCCAT AAGCACTTTC 
CAGCGTGCTT TGAAGGACCC AAATCAACTA ATCCGCGCAA GTGCCTTGAG AGTTTTGTCA 
AGTATTAGAG TGCCGATTAT CGTGCCTGTC ATGATGCTGG CTATCAAGGA GGCATCAGCT 
GACCTGTCGC CCTATGTTAG GAAGAATGCA GCCCATGCTA TCCAGAAGCT GTACAGTCTT 
GACCCTGAGC AGAAGGAGAT GCTGATTGAG GTCATCGAGA AACTCCTGAA GGATAAGAGC 
ACGCTGGTGG CTGGCAGTGT GGTGATGGCT TTTGAAGAGG TGTGCCCAGA TCGAATCGAT 
CTGATCCACA GGAATTACCG CAAGCTTTGT AACCTACTGG TTGATGTTGA AGAGTGGGGG 
CAGGTGGTCA TAATCCATAT GCTAACACGA TACGCTCGGA CCCAGTTCGT TAGTCCTTGG 
AGAGAGGATG ATGGTGTAGA AGACAATGAA AAGAATTTCT ATGATTCTGA CGATGAGGAG 
AAGAAGAGTG GCAAGAAGAA ACCGTACAGC ATGGATCCGG ACCACAGACT CTTAATCAGA 
AACACAAAGC CCTTACTTCA GAGCAGGAAC GCAGCGGTGG TTATGGCTGT CGCTCAGCTG 
TACTGGCACA TCTCACCCAG GTCGGAGGCT GGTGTCATTT CTAAATCGCT GGTGCGCCTA 
CTTCGCAGCC ATAGGGAGGT GCAGTATATT GTATTGCAAA ATATCGCAAC TATGTCAATT 
CAGAGAAAGG GTATGTTTGA ACCTTACCTG AAGAGCTTCT ATGTCCGGTC CACTGATCCA 
ACTATGATCA AGACTCTGAA GCTTGAAATC TTGACAAACT TGGCAAATGA AGCCAACATA 
TCAACTCTTC TTCGAGAATT TCAGACCTAC GTGAGAAGCC AGGACAAACA GTTTGCAGCG 
GCCACTATTC AGACCATAGG CAGATGTGCA ACCAGCATTG CCGAGGTCAC TGACACATGC 
CTCAATGGCC TGGTCTGCCT GCTGTCCAAC AGGGATGAAA TAGTTGTTGC TGAAAGTGTG 
GTTGTTATAA AGAAATTGTT GCAAATGCAG CCTGCACAGC ATGGTGAGAT TATTAAGCAC 
ATGGCGAAGC TGTTGGACAG CATCACTGTC CCTGTGGCTC GAGCAAGCAT TCTTTGGCTG 
ATTGGAGAAA ACTGTGAACG CGTTCCTAAA ATTGCTCCTG ATGTTTTGAG AAAAATGGCT 
AAAAGTTTCA CTAGTGAAGA TGATCTGGTG AAACTGCAGA TTTTAAATCT TGGAGCAAAA 
TTGTATTTAA CTAATTCCAA ACAGACAAAA TTGCTTACCC AGTACATATT AAATCTCGGC 
AAGTATGATC AGAACTACGA CATCAGAGAC CGCACAAGAT TTATTAGGCA GCTTATTGTT 
CCGAACGAGA AGAGTGGAGC TCTAAGTAAA TATGCCAAAA AAATCTTTCT AGCACAGAAG 
CCTGCACCAC TGCTGGAGTC TCCCTTTAAA GACAGGGATC ATTTCCAGCT TGGCACCTTA 
TCTCATACTC TCAACGTTAA AGCGTCCGGG TACCTGGAAT TATCTAATTG GCCAGAGGTG 
GCGCCTGACC CATCGGTTCG CAATGTAGAA GTAATAGAGT CAGCAAAAGA GTGGACCCCA 
CTTGGAAAAA CAAAGAAAGA AAAACCTGAG AAGAAATTTT ATTCAGAATC TGAGGAGGAG 
GAGGAGGAAG AAGAGGAAGA TGAAGAAGAT GAGGAGGAGG ATCCCTCTGA TAGCAGCAGT 
GACAGTGAGA GTGGGTCTGG ACGTGAGAGT GGAGACTCAG GCAGCAGCAG CGAGGACAGC 
AGCGAGGACT CCTCCAGTGG ACAAGACAGC GAGACCGGAA GCGAGGCAGA AGCAGAACAC 
CAGAGGGTGG CCAAGACGAA CTCCAAAACC AAGAGGAAAA GTGCCTCAGA AGACAGGGAG 
AAGAAAAATG GAAAATCTCA GGCCTCGGAG TCGTCCAGTG AGGAGTCCAG TTCCACAGAA 
GAAAGTTCTT CAGAGTCAGA GTCAGGCTCT GACAGTGAGC CTGCACCCAG AAAAACAGCT 
AAGGCAAAAG AAAGAAAACC CCAGCAAGAA AGACATCCTC CCTCCAAAGA TGTTTTCCTT 
CTCGATCTGG ATGACTTTAA CCCAGTATCC ACCCCAGTTG CCCTTCCTAC ACCAGCCCTT 
TCTCCAAGCT TGATAGCTGA TCTTGAAGGT CTAAACCTGT CAACTTCCTC ATCCATCATC 
AACGTCAGTA CACCTGTCTT CGTGCCCACA AAAACACATG AGCTGCTTCA CCGCATGCGT 
GGGAAAGGAC TGGCTGCCCA CTACTGCTTC CCAAGACAGC CTTGCATCTT CGGTGACAAG 
ATGGTCTCTG TACAGATAAC CCTGACCAAT ACTTCCGATG GGAAGATAGA GAACATCCAC 
GTAGGCGGGA AGAAGCTTGC TGTGGGCGTG CAGATGCACG TCTTCCATCC CATAGAGTCT 
CTGGAGCCTG AGGGATCCGT TACTGTCTCG ATGGGTATTG ACTTCTGTGA TTCTACACAG 
ACGGCCAGTT TTCAGCTGTG CACCAAGGAT GATTGCTTCA ACGTCAACAT CCAGCCACCT 
GTTGGGGAGC TGCTTTTACC TGTGGCCATG TCAGAGAAAG ACTTTAAGAA GGAGCAAGGG 
ATGCTCACTG GGATGAATGA GACGTCGGCA ACGCTCATCG CCGCTCCGCA GAACTTCACC 
CCCTCCATGA TCCTCCAGAA GGTTGTAAAC GTCGCCAACC TCGGTGCAGT GCCTTCCAGC 
CAAGATAACA TACACAGGTT TGCAGCTAAA ACTGTGCACA GTGGGTCACT GATGCTAGTC 
ACCGTGGAAC TGAAGGAAGG TTCCACAGCC CAACTTATCA TCAACACCGA GAAAACCGTG 
ATTGGCTCTG TGCTGCTGAG GGAGCTGAAG CCTGTCCTGT CCCAGGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.
The Journal of biological chemistry287(23)19550-63(2012 Jun)
Bultema JJ,Ambrosio AL,Burek CL,Di Pietro SM

Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease.
Molecular medicine (Cambridge, Mass.)1856-64(2012 Feb)
Gochuico BR,Huizing M,Golas GA,Scher CD,Tsokos M,Denver SD,Frei-Jones MJ,Gahl WA

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Molecular biology of the cell22(24)4854-67(2011 Dec)
Larimore J,Tornieri K,Ryder PV,Gokhale A,Zlatic SA,Craige B,Lee JD,Talbot K,Pare JF,Smith Y,Faundez V

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Briefings in bioinformatics12(5)449-62(2011 Sep)
Gaudet P,Livstone MS,Lewis SE,Thomas PD

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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Ap3b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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