Ppp1r3c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ppp1r3c
Entrez Gene ID	309513
Full Name	protein phosphatase 1, regulatory subunit 3C
Synonyms	PTG,R5
General protein information	Preferred Names protein phosphatase 1, regulatory subunit 3C Names protein phosphatase 1 regulatory subunit 3C PP1 subunit R5 protein phosphatase 1 regulatory subunit 3C-like protein phosphatase 1 regulatory subunit 5 protein phosphatase 1, regulatory (inhibitor) subunit 3C protein targeting to glycogen
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q53

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012072.1	NP_001012072.1	protein phosphatase 1 regulatory subunit 3C

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PPP1R3C	XP_534961.3
Rattus norvegicus (Norway rat)	Ppp1r3c	NP_001012072.1
Pan troglodytes (chimpanzee)	PPP1R3C	XP_507911.2
Gallus gallus (chicken)	PPP1R3C	XP_423102.2
	PPP1R3C	XP_001088532.1
Bos taurus (cattle)	PPP1R3C	NP_001069632.1
Mus musculus (house mouse)	Ppp1r3c	NP_058550.1
Homo sapiens (human)	PPP1R3C	NP_005389.1
Rattus norvegicus (Norway rat)	LOC100910671	XP_006231374.1
Danio rerio (zebrafish)	ppp1r3cb	NP_957128.1
Xenopus tropicalis (tropical clawed frog)	ppp1r3c.1	NP_001106579.1

Gene Ontology
Bibliography

Related articles in PubMed

Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis.
Luo X, Zhang Y, Ruan X, Jiang X, Zhu L, Wang X, Ding Q, Liu W, Pan Y, Wang Z, Chen Y
Diabetes60(5)1435-45(2011 May)

PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease.
Turnbull J, DePaoli-Roach AA, Zhao X, Cortez MA, Pencea N, Tiberia E, Piliguian M, Roach PJ, Wang P, Ackerley CA, Minassian BA
PLoS genetics7(4)e1002037(2011 Apr)

A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents.
Munro S, Ceulemans H, Bollen M, Diplexcito J, Cohen PT
The FEBS journal272(6)1478-89(2005 Mar)

Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome research15(1)54-66(2005 Jan)

The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats.
Browne GJ, Delibegovic M, Keppens S, Stalmans W, Cohen PT
The Biochemical journal360(Pt 2)449-59(2001 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ppp1r3c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppp1r3c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42686	NM_001012072.1 Latest version!	Rattus norvegicus protein phosphatase 1, regulatory subunit 3C (Ppp1r3c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ppp1r3c ( NM_001012072.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012072.1 Rattus norvegicus protein phosphatase 1, regulatory subunit 3C (Ppp1r3c), mRNA.

Price & Availability↑

CloneID	ORa42686
Clone ID Related Accession (Same CDS sequence)	NM_001012072.1
Accession Version	NM_001012072.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	protein phosphatase 1 regulatory subunit 3C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085894.1. On Feb 11, 2005 this sequence version replaced XM_220048.2. ##Evidence-Data-START## Transcript exon combination :: FQ123707.1, FQ121796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGCTGCA CCAGGATGAT CCACGTGCTG GATCCACGAC CTTTGACAAG TTCAGTCATG 
CCCGTGGACA TGGCCATGAG GATTTGCTTG GCACATTCAC CACCCCTGAA GAGTTTCCTG 
GGTCCTTACA ATGGTCTTCA GCGAAGACAT TTTGTGAATA AACCGAAGCC CTTGAAACCG 
TGTCTCAGCG TCAAGCAGGA AGCCAAATCA CAGAAGGAAT GGAAGAGCCC ACACAGCCAA 
GCCAAGAAGC GGGTCGTGTT TGCTGACTCC AAGGGGCTCT CCCTCACTGC CATCCACGTC 
TTCTCAGACC TTCCAGAAGA ACCCGCGTGG GACCTGCAGT TTGACCTCTT GGACCTTAAC 
GACATCTCCT CCAGCTTAAA ACTTCACGAG GAGAAAAATC TGGTTTTCGA TTTCCCCCAG 
CCTTCAAGCG ACTACTTAAG TTTCCGGGAC CGCTTCCAGA AGAACTTTGT CTGCCTCGAG 
AACTGCTCTT TGCAAGATCG GACAGTGACT GGGACGGTCA AAGTAAAGAA CGTGAGCTTC 
GAGAAGAAGG TTCAGGTCCG CATCACCTTT GACACCTGGA AAACCTACAC CGACGTGGAC 
TGTGTATACT TGAAGAACGT TTACGGCAGC TCAGACAGTG ACACCTTCTC CTTTGCCATC 
GACTTGCCCC GCGTCATTCC AACTGAGGAG AAAATCGAGT TCTGCATTTC CTACCATGCT 
AACGGGAGGG TCTTCTGGGA CAACAACGAG GCTCAGAACT ATAGAATTGT CCATGTACAG 
TGGAAACCCG ACGGAGTGCA GACTCAGGTG GCACCCAAAG ACTGTGCATT CCAACAGGTG 
CCCCTTAAGA CTGAGTTAGA ACCCACGGTC TTTGGCAGTC CGAGGCTTGC TAGCGGCCTC 
TTCCCAGAGT GGCAGAGCTG GGGGAGAGTG GAGAACTTGG CCTCCTATCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012072.1
CDS	89..1042
Translation	MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHSPPLKSFLGPYNGLQRRHFVNKPKPLKPCLSVKQEAKSQKEWKSPHSQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSSLKLHEEKNLVFDFPQPSSDYLSFRDRFQKNFVCLENCSLQDRTVTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKNVYGSSDSDTFSFAIDLPRVIPTEEKIEFCISYHANGRVFWDNNEAQNYRIVHVQWKPDGVQTQVAPKDCAFQQVPLKTELEPTVFGSPRLASGLFPEWQSWGRVENLASYR

Target ORF information:

RefSeq Version	NM_001012072.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein phosphatase 1, regulatory subunit 3C (Ppp1r3c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012072.1

ORF Insert Sequence:

ATGAGCTGCA CCAGGATGAT CCACGTGCTG GATCCACGAC CTTTGACAAG TTCAGTCATG 
CCCGTGGACA TGGCCATGAG GATTTGCTTG GCACATTCAC CACCCCTGAA GAGTTTCCTG 
GGTCCTTACA ATGGTCTTCA GCGAAGACAT TTTGTGAATA AACCGAAGCC CTTGAAACCG 
TGTCTCAGCG TCAAGCAGGA AGCCAAATCA CAGAAGGAAT GGAAGAGCCC ACACAGCCAA 
GCCAAGAAGC GGGTCGTGTT TGCTGACTCC AAGGGGCTCT CCCTCACTGC CATCCACGTC 
TTCTCAGACC TTCCAGAAGA ACCCGCGTGG GACCTGCAGT TTGACCTCTT GGACCTTAAC 
GACATCTCCT CCAGCTTAAA ACTTCACGAG GAGAAAAATC TGGTTTTCGA TTTCCCCCAG 
CCTTCAAGCG ACTACTTAAG TTTCCGGGAC CGCTTCCAGA AGAACTTTGT CTGCCTCGAG 
AACTGCTCTT TGCAAGATCG GACAGTGACT GGGACGGTCA AAGTAAAGAA CGTGAGCTTC 
GAGAAGAAGG TTCAGGTCCG CATCACCTTT GACACCTGGA AAACCTACAC CGACGTGGAC 
TGTGTATACT TGAAGAACGT TTACGGCAGC TCAGACAGTG ACACCTTCTC CTTTGCCATC 
GACTTGCCCC GCGTCATTCC AACTGAGGAG AAAATCGAGT TCTGCATTTC CTACCATGCT 
AACGGGAGGG TCTTCTGGGA CAACAACGAG GCTCAGAACT ATAGAATTGT CCATGTACAG 
TGGAAACCCG ACGGAGTGCA GACTCAGGTG GCACCCAAAG ACTGTGCATT CCAACAGGTG 
CCCCTTAAGA CTGAGTTAGA ACCCACGGTC TTTGGCAGTC CGAGGCTTGC TAGCGGCCTC 
TTCCCAGAGT GGCAGAGCTG GGGGAGAGTG GAGAACTTGG CCTCCTATCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis.
Diabetes60(5)1435-45(2011 May)
Luo X,Zhang Y,Ruan X,Jiang X,Zhu L,Wang X,Ding Q,Liu W,Pan Y,Wang Z,Chen Y

PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease.
PLoS genetics7(4)e1002037(2011 Apr)
Turnbull J,DePaoli-Roach AA,Zhao X,Cortez MA,Pencea N,Tiberia E,Piliguian M,Roach PJ,Wang P,Ackerley CA,Minassian BA

A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents.
The FEBS journal272(6)1478-89(2005 Mar)
Munro S,Ceulemans H,Bollen M,Diplexcito J,Cohen PT

Gene and alternative splicing annotation with AIR.
Genome research15(1)54-66(2005 Jan)
Florea L,Di Francesco V,Miller J,Turner R,Yao A,Harris M,Walenz B,Mobarry C,Merkulov GV,Charlab R,Dew I,Deng Z,Istrail S,Li P,Sutton G

The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats.
The Biochemical journal360(Pt 2)449-59(2001 Dec)
Browne GJ,Delibegovic M,Keppens S,Stalmans W,Cohen PT