Clca1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clca1
Entrez Gene ID	308015
Full Name	chloride channel accessory 1
Synonyms	Clca3
General protein information	Preferred Names chloride channel accessory 1 Names calcium-activated chloride channel regulator 1 chloride channel calcium activated 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q44

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107449.1	NP_001100919.1	calcium-activated chloride channel regulator 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CLCA1	XP_001143250.1
	CLCA1	NP_001028084.1
Mus musculus (house mouse)	Clca3	NP_059502.1
Canis lupus familiaris (dog)	CLCA1	XP_547299.2
Bos taurus (cattle)	CLCA1	NP_001193105.1
Homo sapiens (human)	CLCA1	NP_001276.2
Rattus norvegicus (Norway rat)	Clca1	NP_001100919.1

Gene Ontology
Bibliography

Related articles in PubMed

rbCLCA1 is a putative metalloprotease family member: localization and catalytic domain identification.
Lee RM, Han KH, Han JS
Amino acids48(3)707-20(2016 Mar)

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.
Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA
Developmental biology375(2)128-39(2013 Mar)

[Effects of glucocorticoid on calcium-activated chloride channel expression in nasal mucosa in allergic rhinitis rats].
Wu WL, Zhen HT, Gao M
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery44(3)242-5(2009 Mar)

Hypoxic/ischemic conditions induce expression of the putative pro-death gene Clca1 via activation of extrasynaptic N-methyl-D-aspartate receptors.
Wahl AS, Buchthal B, Rode F, Bomholt SF, Freitag HE, Hardingham GE, R?nn LC, Bading H
Neuroscience158(1)344-52(2009 Jan)

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.
Woodruff PG, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV
Proceedings of the National Academy of Sciences of the United States of America104(40)15858-63(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

amino acids H159 and E167 in the rbCLCA1 metalloprotease motif are important in rbCLCA1 processing for localization to the cell surface.
Title: rbCLCA1 is a putative metalloprotease family member: localization and catalytic domain identification.

Dexamethasone substantially downregulates the expression of CLCA3 mRNA and Muc5ac protein in nasal mucosa in allergic rhinitis.
Title: [Effects of glucocorticoid on calcium-activated chloride channel expression in nasal mucosa in allergic rhinitis rats].

The following Clca1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clca1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03562	NM_001107449.1 Latest version!	Rattus norvegicus chloride channel accessory 1 (Clca1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clca1 ( NM_001107449.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100919.1 Rattus norvegicus chloride channel accessory 1 (Clca1), mRNA.

Price & Availability↑

CloneID	ORa03562
Clone ID Related Accession (Same CDS sequence)	NM_001107449.1
Accession Version	NM_001107449.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2733bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	calcium-activated chloride channel regulator 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473952.1. On or before Oct 4, 2007 this sequence version replaced XM_217689.4, XM_001079217.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGGGATCTT TGAAGAGTCC TGTCTTCCTC TTGGTCCTCT ACCTTCTGGA AGGGGTTCTG 
AGCAATTCCC TCATCCAGTT GAACAACAAT GGCTATGAAG GCATCGTCAT TGCCATAGAC 
CACGATGTGC CAGAAGATGA AGCCCTCATC CAACGGATAA AGGACATGGT GACTCAGGCC 
TCTCCATACC TGTTTGAAGC TACAGGGAAA AGATTTTACT TCAAAAATGT TGCCATTTTG 
ATTCCTGAGA ATTGGAACAC AAAACCTGAA TATAAGAGGC CAAAACTTGA AACCTTAAAA 
AATGCTGATG TCCTTGTGTC AACAATGAGC CCCATAGGTA ATGATGAGCC CTACACCGAG 
CACATAGGAG CATGTGGAGA AAGGGGGATC AGGATTCACC TGACTCCTGA CTTCTTAGCA 
GGAAAGAAGC AGACTGAGTA TGGCCCACAA GACAGGACGT TTGTTCATGA GTGGGCTCAC 
TTCCGATGGG GGGTGTTTGA CGAGTACAAC AACAACGAGA AGTTCTACTT GTCCAACGGA 
AAGCCCCAGG CAGTAAGATG TTCGGCAACC ATTACCGGTA AACATGTAGT TCGTCGGTGC 
CAGGGAGGCA GTTGCGTCAC TAACGGAAAG TGCGTAATCG ACAGAGTAAC GGGACTGTAT 
AAAGATAACT GTGTATTCAT ACCAGATAAA AACCAGAGAG AGAAGGCGTC CATCATGTTT 
AACCAAAATA TCAACTCTGT GGTTGAATTC TGTACAGAAA AAAATCACAA TAAAGAAGCC 
CCCAATGCCC AAAACCAACG ATGCAACCTC CGAAGCACTT GGGAAGTCAT CCAGGAATCT 
GAGGACTTCA AGCAAACCAC TCCCATGACA GCCCAGCCAC CCGCACCCAC CTTCTCACTG 
CTGCAAACCA GACAAAGAAT CGTGTGCCTC GTTCTTGATA AGTCCGGGAG CATGCAGAGC 
GATAACCGTC TTAACCGAAT GAATCAGGCA AGCCGGCTTT TCCTGCTGCA GACTGTGGAG 
CAGGGATCCT GGGTCGGGAT GGTGACCTTC GACAGTACCG CCTATGTACA AAGCGAACTC 
ACACAGTTAA ACAGTGGTGC TGACAGAGAC CTGCTGATCA AGCGCTTACC CACAGTAGCT 
TCAGGAGGGA CGTCTATATG CTCTGGGCTT CAGGCAGCAT TTACATCGAT AAAGAAGAAG 
TACCCGACGG ATGGAGCTGA AATCGTGCTG CTGACCGACG GGGAAGATAA CACCATTAGC 
AGCTGCTTTG ACCTGGTGAA GAACAGTGGG GCCATCATTC ACACAGTGGC CCTGGGACCG 
TCTGCCGCTA AAGAGCTTGA ACAGCTGTCC AAAATGACAG GAGGCTTGCA AACGTATTCT 
TCCGATCAGA TTCAGAACAA CGGTCTTGTT GATGCTTTCG CAGCTCTCTC CTCAGGAAAT 
GCAGCTATCT CTCAGCACTC CATCCAGCTG GAGAGCAGAG GAGTTAATCT CCAGAATAAG 
CAGTGGATGA ATGGCTCAGT GATCGTGGAC AGCACAGTGG GGAAGGACAC CTTGTTTCTT 
GTCACCTGGA CTACGAATTC TCCTTCAATA TTTATCTGGG ATCCCAGTGG AGTGCAACAA 
AGTGGTTTTG TACTAGACAC CAACACCAAG GTGGCCTACC TCCAAGTCCC AGGCATAGCC 
AAGGTTGGCT TTTGGAAATA CAGCATTCAA GCGAGCTCAC AGACTCTCAC TTTGACTGTC 
ACCTCCCGGG CAGCAAGCGC TACACTGCCT CCAATTACAG TGACCCCAGT AGTGAATAAG 
AACACAGGGA AATTCCCCAG CCCTGTAACC GTGTATGCAA GCATTCGCCA AGGAGCCTCG 
CCTATTCTCA GGGCCAGTGT CACAGCCCTG ATTGAATCTG TGAATGGAAA AACAGTAACC 
CTGGAATTAC TGGATAACGG AGCAGGTGCC GATGCTACCA AGAATGATGG TGTCTACTCA 
AGGTTTTTTA CAGCTTTTGA TGCAAATGGT AGATACAGCA TCAAAATATG GGCTCTGGGA 
GGAGTTACTG CAGACAGACA GAGAATGGCC CCTCAGAGGA ATGGAGTCAT GTACATAGAT 
GGCTGGATTG AAGACGACGG TGAAATAAAA ATGAATCCAC CACACCCTGA AACTGGTAAT 
GTTCAAGACA GCCAAGTGTG CTTCAGCAGG ACATCCTCAG GGGGATCGTT TGTGGCCACC 
AACGTCCCCG CAGCTCCCAT TCCTGACCTC TTTCCACCTT GCCAAATCAC TGACCTGAAG 
GCTAGCATTC AAGGGCAGAA CCTTGTGAAT CTGACGTGGA CGGCTCCTGG GGATGATTAC 
GACCACGGGA GAGCTTCCAG TTACATCATC CGAATAAGCA CGAGTATCGT CGATCTCAGA 
AACAACTTCA GCACCTCACT CGAAGTGAAC ACTACCGATC TCATCCCCAA GGAGGCCAGC 
TCCGAGGAAA TGTTTGAGTT TGAACTGGAC AACAGCTTTG GAAATGGCAC AGATGTCTTC 
ATTGCTATCC AGGCTGTGGA TAAGTCCAAC CTGAAATCAG AAATCTCCAA CATTGCCCGG 
GTGTCTCTGT TCATCCCCGC TCAGGAGCCG CCAGAAGACT CAACTCCTTC TTATCCCGAA 
GTCAGCATCA ACAGCACGAT TCCTGGCATC CACGTGCTGA ATATAGTGTG GAAGTGGCTA 
GGGGAAATGC ATGTGACACT AGGTTTGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100919.1
CDS	15..2747
Translation	MGSLKSPVFLLVLYLLEGVLSNSLIQLNNNGYEGIVIAIDHDVPEDEALIQRIKDMVTQASPYLFEATGKRFYFKNVAILIPENWNTKPEYKRPKLETLKNADVLVSTMSPIGNDEPYTEHIGACGERGIRIHLTPDFLAGKKQTEYGPQDRTFVHEWAHFRWGVFDEYNNNEKFYLSNGKPQAVRCSATITGKHVVRRCQGGSCVTNGKCVIDRVTGLYKDNCVFIPDKNQREKASIMFNQNINSVVEFCTEKNHNKEAPNAQNQRCNLRSTWEVIQESEDFKQTTPMTAQPPAPTFSLLQTRQRIVCLVLDKSGSMQSDNRLNRMNQASRLFLLQTVEQGSWVGMVTFDSTAYVQSELTQLNSGADRDLLIKRLPTVASGGTSICSGLQAAFTSIKKKYPTDGAEIVLLTDGEDNTISSCFDLVKNSGAIIHTVALGPSAAKELEQLSKMTGGLQTYSSDQIQNNGLVDAFAALSSGNAAISQHSIQLESRGVNLQNKQWMNGSVIVDSTVGKDTLFLVTWTTNSPSIFIWDPSGVQQSGFVLDTNTKVAYLQVPGIAKVGFWKYSIQASSQTLTLTVTSRAASATLPPITVTPVVNKNTGKFPSPVTVYASIRQGASPILRASVTALIESVNGKTVTLELLDNGAGADATKNDGVYSRFFTAFDANGRYSIKIWALGGVTADRQRMAPQRNGVMYIDGWIEDDGEIKMNPPHPETGNVQDSQVCFSRTSSGGSFVATNVPAAPIPDLFPPCQITDLKASIQGQNLVNLTWTAPGDDYDHGRASSYIIRISTSIVDLRNNFSTSLEVNTTDLIPKEASSEEMFEFELDNSFGNGTDVFIAIQAVDKSNLKSEISNIARVSLFIPAQEPPEDSTPSYPEVSINSTIPGIHVLNIVWKWLGEMHVTLGLH

Target ORF information:

RefSeq Version	NM_001107449.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus chloride channel accessory 1 (Clca1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107449.1

ORF Insert Sequence:

ATGGGATCTT TGAAGAGTCC TGTCTTCCTC TTGGTCCTCT ACCTTCTGGA AGGGGTTCTG 
AGCAATTCCC TCATCCAGTT GAACAACAAT GGCTATGAAG GCATCGTCAT TGCCATAGAC 
CACGATGTGC CAGAAGATGA AGCCCTCATC CAACGGATAA AGGACATGGT GACTCAGGCC 
TCTCCATACC TGTTTGAAGC TACAGGGAAA AGATTTTACT TCAAAAATGT TGCCATTTTG 
ATTCCTGAGA ATTGGAACAC AAAACCTGAA TATAAGAGGC CAAAACTTGA AACCTTAAAA 
AATGCTGATG TCCTTGTGTC AACAATGAGC CCCATAGGTA ATGATGAGCC CTACACCGAG 
CACATAGGAG CATGTGGAGA AAGGGGGATC AGGATTCACC TGACTCCTGA CTTCTTAGCA 
GGAAAGAAGC AGACTGAGTA TGGCCCACAA GACAGGACGT TTGTTCATGA GTGGGCTCAC 
TTCCGATGGG GGGTGTTTGA CGAGTACAAC AACAACGAGA AGTTCTACTT GTCCAACGGA 
AAGCCCCAGG CAGTAAGATG TTCGGCAACC ATTACCGGTA AACATGTAGT TCGTCGGTGC 
CAGGGAGGCA GTTGCGTCAC TAACGGAAAG TGCGTAATCG ACAGAGTAAC GGGACTGTAT 
AAAGATAACT GTGTATTCAT ACCAGATAAA AACCAGAGAG AGAAGGCGTC CATCATGTTT 
AACCAAAATA TCAACTCTGT GGTTGAATTC TGTACAGAAA AAAATCACAA TAAAGAAGCC 
CCCAATGCCC AAAACCAACG ATGCAACCTC CGAAGCACTT GGGAAGTCAT CCAGGAATCT 
GAGGACTTCA AGCAAACCAC TCCCATGACA GCCCAGCCAC CCGCACCCAC CTTCTCACTG 
CTGCAAACCA GACAAAGAAT CGTGTGCCTC GTTCTTGATA AGTCCGGGAG CATGCAGAGC 
GATAACCGTC TTAACCGAAT GAATCAGGCA AGCCGGCTTT TCCTGCTGCA GACTGTGGAG 
CAGGGATCCT GGGTCGGGAT GGTGACCTTC GACAGTACCG CCTATGTACA AAGCGAACTC 
ACACAGTTAA ACAGTGGTGC TGACAGAGAC CTGCTGATCA AGCGCTTACC CACAGTAGCT 
TCAGGAGGGA CGTCTATATG CTCTGGGCTT CAGGCAGCAT TTACATCGAT AAAGAAGAAG 
TACCCGACGG ATGGAGCTGA AATCGTGCTG CTGACCGACG GGGAAGATAA CACCATTAGC 
AGCTGCTTTG ACCTGGTGAA GAACAGTGGG GCCATCATTC ACACAGTGGC CCTGGGACCG 
TCTGCCGCTA AAGAGCTTGA ACAGCTGTCC AAAATGACAG GAGGCTTGCA AACGTATTCT 
TCCGATCAGA TTCAGAACAA CGGTCTTGTT GATGCTTTCG CAGCTCTCTC CTCAGGAAAT 
GCAGCTATCT CTCAGCACTC CATCCAGCTG GAGAGCAGAG GAGTTAATCT CCAGAATAAG 
CAGTGGATGA ATGGCTCAGT GATCGTGGAC AGCACAGTGG GGAAGGACAC CTTGTTTCTT 
GTCACCTGGA CTACGAATTC TCCTTCAATA TTTATCTGGG ATCCCAGTGG AGTGCAACAA 
AGTGGTTTTG TACTAGACAC CAACACCAAG GTGGCCTACC TCCAAGTCCC AGGCATAGCC 
AAGGTTGGCT TTTGGAAATA CAGCATTCAA GCGAGCTCAC AGACTCTCAC TTTGACTGTC 
ACCTCCCGGG CAGCAAGCGC TACACTGCCT CCAATTACAG TGACCCCAGT AGTGAATAAG 
AACACAGGGA AATTCCCCAG CCCTGTAACC GTGTATGCAA GCATTCGCCA AGGAGCCTCG 
CCTATTCTCA GGGCCAGTGT CACAGCCCTG ATTGAATCTG TGAATGGAAA AACAGTAACC 
CTGGAATTAC TGGATAACGG AGCAGGTGCC GATGCTACCA AGAATGATGG TGTCTACTCA 
AGGTTTTTTA CAGCTTTTGA TGCAAATGGT AGATACAGCA TCAAAATATG GGCTCTGGGA 
GGAGTTACTG CAGACAGACA GAGAATGGCC CCTCAGAGGA ATGGAGTCAT GTACATAGAT 
GGCTGGATTG AAGACGACGG TGAAATAAAA ATGAATCCAC CACACCCTGA AACTGGTAAT 
GTTCAAGACA GCCAAGTGTG CTTCAGCAGG ACATCCTCAG GGGGATCGTT TGTGGCCACC 
AACGTCCCCG CAGCTCCCAT TCCTGACCTC TTTCCACCTT GCCAAATCAC TGACCTGAAG 
GCTAGCATTC AAGGGCAGAA CCTTGTGAAT CTGACGTGGA CGGCTCCTGG GGATGATTAC 
GACCACGGGA GAGCTTCCAG TTACATCATC CGAATAAGCA CGAGTATCGT CGATCTCAGA 
AACAACTTCA GCACCTCACT CGAAGTGAAC ACTACCGATC TCATCCCCAA GGAGGCCAGC 
TCCGAGGAAA TGTTTGAGTT TGAACTGGAC AACAGCTTTG GAAATGGCAC AGATGTCTTC 
ATTGCTATCC AGGCTGTGGA TAAGTCCAAC CTGAAATCAG AAATCTCCAA CATTGCCCGG 
GTGTCTCTGT TCATCCCCGC TCAGGAGCCG CCAGAAGACT CAACTCCTTC TTATCCCGAA 
GTCAGCATCA ACAGCACGAT TCCTGGCATC CACGTGCTGA ATATAGTGTG GAAGTGGCTA 
GGGGAAATGC ATGTGACACT AGGTTTGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

rbCLCA1 is a putative metalloprotease family member: localization and catalytic domain identification.
Amino acids48(3)707-20(2016 Mar)
Lee RM,Han KH,Han JS

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.
Developmental biology375(2)128-39(2013 Mar)
Bell SM,Zhang L,Xu Y,Besnard V,Wert SE,Shroyer N,Whitsett JA

[Effects of glucocorticoid on calcium-activated chloride channel expression in nasal mucosa in allergic rhinitis rats].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery44(3)242-5(2009 Mar)
Wu WL,Zhen HT,Gao M

Hypoxic/ischemic conditions induce expression of the putative pro-death gene Clca1 via activation of extrasynaptic N-methyl-D-aspartate receptors.
Neuroscience158(1)344-52(2009 Jan)
Wahl AS,Buchthal B,Rode F,Bomholt SF,Freitag HE,Hardingham GE,R?nn LC,Bading H

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.
Proceedings of the National Academy of Sciences of the United States of America104(40)15858-63(2007 Oct)
Woodruff PG,Boushey HA,Dolganov GM,Barker CS,Yang YH,Donnelly S,Ellwanger A,Sidhu SS,Dao-Pick TP,Pantoja C,Erle DJ,Yamamoto KR,Fahy JV

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Clca1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報