Vps41 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vps41
Entrez Gene ID	306991
Full Name	VPS41 HOPS complex subunit
Synonyms	RGD1560511
General protein information	Preferred Names VPS41 HOPS complex subunit Names vacuolar protein sorting-associated protein 41 homolog Vam2 vacuolar protein sorting 41 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107355.1	NP_001100825.1	vacuolar protein sorting-associated protein 41 homolog

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	VPS41	XP_533084.2
Mus musculus (house mouse)	Vps41	NP_742118.3
Oryza sativa (rice)	Os04g0195000	NP_001052213.1
Xenopus tropicalis (tropical clawed frog)	vps41	XP_004912577.1
Pan troglodytes (chimpanzee)	VPS41	XP_519057.3
	VPS41	XP_001101460.2
Rattus norvegicus (Norway rat)	Vps41	NP_001100825.1
Drosophila melanogaster (fruit fly)	lt	NP_001260695.1
Homo sapiens (human)	VPS41	NP_055211.2
Danio rerio (zebrafish)	vps41	XP_691671.2
Bos taurus (cattle)	VPS41	NP_001076922.1
Gallus gallus (chicken)	VPS41	NP_001012877.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009174	XP_319939.4
Arabidopsis thaliana (thale cress)	VPS41	NP_172297.2

Gene Ontology
Bibliography

Related articles in PubMed

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.
Wartosch L, G?nesdogan U, Graham SC, Luzio JP
Traffic (Copenhagen, Denmark)16(7)727-42(2015 Jul)

Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.
Asensio CS, Sirkis DW, Maas JW Jr, Egami K, To TL, Brodsky FM, Shu X, Cheng Y, Edwards RH
Developmental cell27(4)425-37(2013 Nov)

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Graham SC, Wartosch L, Gray SR, Scourfield EJ, Deane JE, Luzio JP, Owen DJ
Proceedings of the National Academy of Sciences of the United States of America110(33)13345-50(2013 Aug)

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion.
Pols MS, ten Brink C, Gosavi P, Oorschot V, Klumperman J
Traffic (Copenhagen, Denmark)14(2)219-32(2013 Feb)

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.
Zlatic SA, Tornieri K, L'Hernault SW, Faundez V
Molecular biology of the cell22(10)1699-715(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Vps41 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vps41 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39842	NM_001107355.1 Latest version!	Rattus norvegicus VPS41 subunit of HOPS complex (Vps41), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vps41 ( NM_001107355.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100825.1 Rattus norvegicus VPS41 subunit of HOPS complex (Vps41), mRNA.

Price & Availability↑

CloneID	ORa39842
Clone ID Related Accession (Same CDS sequence)	NM_001107355.1
Accession Version	NM_001107355.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2238bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Rattus norvegicus(Norway rat)
Product	vacuolar protein sorting-associated protein 41 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474030.1. On Oct 4, 2007 this sequence version replaced XM_001053199.1.

ATGGCGGAAG CAGAGGAGCA GGAAACTGAG TCTCTTGAAG AATCTACAGA TGAGTCAGAG 
GAAGAGAGTG AAGAGGAACC CAAACTGAAG TATGAAAGGC TTTCTAATGG GGTGACAGAG 
ATTCTTCAGA AAGATGCAGC AAGCTGTATG ACGGTCCATG ACAAGTTTTT GGCACTGGGC 
ACACACTATG GCAAGGTTTA TTTACTGGAC GTCCAGGGAA ACATCACTCA GAAGTTTGAT 
GTAAGTCCTG TGAAGATAAA CCAGATCAGC TTGGATGAAA GCGGAGAACA TATGGGCGTG 
TGCTCGGAGG ATGGCAAGCT GCAGGTCTTT GGACTGTACT CTGGAGAAGA ATTCCATGAG 
ACTTTCGACT GTCCCATTAA AATCGTTGCT GTGCACCCCC AGTTCGTGAG ATCCAGTTGT 
AAGCAGTTCG TGACTGGTGG GAAAAAGTTG CTGCTATTTG AACGGACGTG GATGAACAGA 
TGGAAGTCTT CTGTCCTGCA CGAAGGGGAA GGGAACATAA GGAGCGTGAA GTGGAGAGGC 
CATCTGATTG CCTGGGCCAA CAACATGGGT GTGAAGATTT TTGACATCAC CTCAAAGCAA 
AGAATCACCA ACGTTCCCCG AGATGATATA AGTCTTCGCC CAGATATGTA TCCCTGCAGC 
CTCTGCTGGA AGGATGCTGT GACACTGATT ATCGGCTGGG GAACTTCCAT CAAGATATGC 
TCAGTGAAGG AACGCCATGC CAGTGAGATG AGGGATCTGC CAAGTCGATA CGTTGAAATA 
GTGTCTCAAT TTGAAACTGA ATTCTACATT AGTGGACTTG CACCTCTCTG TGATCAGCTT 
GTTGTACTTT CCTACGTAAA GGAGGTTTCG GAAAAAACGG AAAGAGAATA CTGTGCAAGA 
CCGAGACTGG ACATCATCCA GCCACTTCCA GAGACTTGTG AAGAGATCTC ATCTGATGCT 
TTGACAGTCA GAGGTTTTCA GGAGAATGAA TGTAGGGATT ACCACCTAGA ATACTCTGAA 
GGGGAATCAC TCTTCTACGT CGTGAGTCCA AGAGATGTCG TCGTAGCCAA GGAGCGAGAC 
CAGGATGATC ATATCGACTG GCTCCTTGAG AAGAAGAAAT ATGAAGAAGC TTTGATGGCA 
GCTGAAATTA GCCACAGGAA CATTAAAAGA CATAAGATTC TGGAGATCGG GTTGGCATAT 
GTAAACCACC TGGTGGAGAG AGGCGAGTAC GACATGGCCG CACGAAAATG CCAGAAAATT 
CTTGGGAAAA ATGCATCCCT CTGGGAATAC GAAGTTTACA AATTTAAAGA AATTGGACAG 
CTTAAAGCAA TTAGTCCCTA TTTACCTCGA GGGGACCCCG TTCTGAAACC ACTCATCTAT 
GAAATGATTT TGCACGAATT TCTGGAAAGT GATTATGAGG GCTTTGCCAC ATTGATCAGA 
GAATGGCCTG GAGATCTGTA TAACAATTCT GTGATAGTTC AAGCAGTTCG AGACCACCTG 
AAGAAGGACA GTCAGAACAA GACTTTATTG AAAACACTGG CAGAATTGTA TACCTATGAC 
AAAAATTATG GCAATGCTCT GGAAATATAC TTAACGTTAA GACATAAAGA TGTTTTCCAA 
CTGATACACA AGCATAATCT TTTCAGCTCC ATCAAGGATA AAATTGTTTT ATTAATGGAC 
TTTGATTCAG AGAAAGCTGT TGACATGCTT TTGGACAATG AAGATAAAAT TTCAATTAAA 
AAAGTGGTAG AAGAATTAGA AGACAGGCCA GAGCTGCAGC ATGTGTATTT GCACAAGCTC 
TTCAAGAGAG ACCATCATAA GGGACAGCGC TACCATGAAA AACAGATCAG TCTGTATGCC 
GAATATGATC GACCAAACCT ACTGCCCTTT CTCCGAGACA GTACCCATTG CCCACTAGAA 
AAGGCTCTTG AGATCTGTCA ACAAAGAAAC TTTGTAGAAG AGACAGTTTA CCTTCTGAGC 
CGAATGGGAA ACAGTCGAAG TGCCCTGAAG ATGATTATGG AGGAATTGCA TGATGTTGAT 
AAAGCAATTG AGTTTGCCAA GGAACAAGAT GATGGAGAGC TCTGGGAAGA TCTGATTCTA 
TATTCCATTG ACAAACCACC ATTTATCACT GGCTTGTTGA ACAACATTGG CACACACATG 
CAGCGAAGCC CTTCAGCGTG GTGGTCTTCC ATTGTCGGCA CATGTTCCAC AAGGAGTGCC 
TACCTATGCC AAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100825.1
CDS	19..2256
Translation	MAEAEEQETESLEESTDESEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKLQVFGLYSGEEFHETFDCPIKIVAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDITSKQRITNVPRDDISLRPDMYPCSLCWKDAVTLIIGWGTSIKICSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISHRNIKRHKILEIGLAYVNHLVERGEYDMAARKCQKILGKNASLWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHMQRSPSAWWSSIVGTCSTRSAYLCQA

Target ORF information:

RefSeq Version	NM_001107355.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus VPS41 subunit of HOPS complex (Vps41), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107355.1

ORF Insert Sequence:

ATGGCGGAAG CAGAGGAGCA GGAAACTGAG TCTCTTGAAG AATCTACAGA TGAGTCAGAG 
GAAGAGAGTG AAGAGGAACC CAAACTGAAG TATGAAAGGC TTTCTAATGG GGTGACAGAG 
ATTCTTCAGA AAGATGCAGC AAGCTGTATG ACGGTCCATG ACAAGTTTTT GGCACTGGGC 
ACACACTATG GCAAGGTTTA TTTACTGGAC GTCCAGGGAA ACATCACTCA GAAGTTTGAT 
GTAAGTCCTG TGAAGATAAA CCAGATCAGC TTGGATGAAA GCGGAGAACA TATGGGCGTG 
TGCTCGGAGG ATGGCAAGCT GCAGGTCTTT GGACTGTACT CTGGAGAAGA ATTCCATGAG 
ACTTTCGACT GTCCCATTAA AATCGTTGCT GTGCACCCCC AGTTCGTGAG ATCCAGTTGT 
AAGCAGTTCG TGACTGGTGG GAAAAAGTTG CTGCTATTTG AACGGACGTG GATGAACAGA 
TGGAAGTCTT CTGTCCTGCA CGAAGGGGAA GGGAACATAA GGAGCGTGAA GTGGAGAGGC 
CATCTGATTG CCTGGGCCAA CAACATGGGT GTGAAGATTT TTGACATCAC CTCAAAGCAA 
AGAATCACCA ACGTTCCCCG AGATGATATA AGTCTTCGCC CAGATATGTA TCCCTGCAGC 
CTCTGCTGGA AGGATGCTGT GACACTGATT ATCGGCTGGG GAACTTCCAT CAAGATATGC 
TCAGTGAAGG AACGCCATGC CAGTGAGATG AGGGATCTGC CAAGTCGATA CGTTGAAATA 
GTGTCTCAAT TTGAAACTGA ATTCTACATT AGTGGACTTG CACCTCTCTG TGATCAGCTT 
GTTGTACTTT CCTACGTAAA GGAGGTTTCG GAAAAAACGG AAAGAGAATA CTGTGCAAGA 
CCGAGACTGG ACATCATCCA GCCACTTCCA GAGACTTGTG AAGAGATCTC ATCTGATGCT 
TTGACAGTCA GAGGTTTTCA GGAGAATGAA TGTAGGGATT ACCACCTAGA ATACTCTGAA 
GGGGAATCAC TCTTCTACGT CGTGAGTCCA AGAGATGTCG TCGTAGCCAA GGAGCGAGAC 
CAGGATGATC ATATCGACTG GCTCCTTGAG AAGAAGAAAT ATGAAGAAGC TTTGATGGCA 
GCTGAAATTA GCCACAGGAA CATTAAAAGA CATAAGATTC TGGAGATCGG GTTGGCATAT 
GTAAACCACC TGGTGGAGAG AGGCGAGTAC GACATGGCCG CACGAAAATG CCAGAAAATT 
CTTGGGAAAA ATGCATCCCT CTGGGAATAC GAAGTTTACA AATTTAAAGA AATTGGACAG 
CTTAAAGCAA TTAGTCCCTA TTTACCTCGA GGGGACCCCG TTCTGAAACC ACTCATCTAT 
GAAATGATTT TGCACGAATT TCTGGAAAGT GATTATGAGG GCTTTGCCAC ATTGATCAGA 
GAATGGCCTG GAGATCTGTA TAACAATTCT GTGATAGTTC AAGCAGTTCG AGACCACCTG 
AAGAAGGACA GTCAGAACAA GACTTTATTG AAAACACTGG CAGAATTGTA TACCTATGAC 
AAAAATTATG GCAATGCTCT GGAAATATAC TTAACGTTAA GACATAAAGA TGTTTTCCAA 
CTGATACACA AGCATAATCT TTTCAGCTCC ATCAAGGATA AAATTGTTTT ATTAATGGAC 
TTTGATTCAG AGAAAGCTGT TGACATGCTT TTGGACAATG AAGATAAAAT TTCAATTAAA 
AAAGTGGTAG AAGAATTAGA AGACAGGCCA GAGCTGCAGC ATGTGTATTT GCACAAGCTC 
TTCAAGAGAG ACCATCATAA GGGACAGCGC TACCATGAAA AACAGATCAG TCTGTATGCC 
GAATATGATC GACCAAACCT ACTGCCCTTT CTCCGAGACA GTACCCATTG CCCACTAGAA 
AAGGCTCTTG AGATCTGTCA ACAAAGAAAC TTTGTAGAAG AGACAGTTTA CCTTCTGAGC 
CGAATGGGAA ACAGTCGAAG TGCCCTGAAG ATGATTATGG AGGAATTGCA TGATGTTGAT 
AAAGCAATTG AGTTTGCCAA GGAACAAGAT GATGGAGAGC TCTGGGAAGA TCTGATTCTA 
TATTCCATTG ACAAACCACC ATTTATCACT GGCTTGTTGA ACAACATTGG CACACACATG 
CAGCGAAGCC CTTCAGCGTG GTGGTCTTCC ATTGTCGGCA CATGTTCCAC AAGGAGTGCC 
TACCTATGCC AAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.
Traffic (Copenhagen, Denmark)16(7)727-42(2015 Jul)
Wartosch L,G?nesdogan U,Graham SC,Luzio JP

Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.
Developmental cell27(4)425-37(2013 Nov)
Asensio CS,Sirkis DW,Maas JW Jr,Egami K,To TL,Brodsky FM,Shu X,Cheng Y,Edwards RH

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Proceedings of the National Academy of Sciences of the United States of America110(33)13345-50(2013 Aug)
Graham SC,Wartosch L,Gray SR,Scourfield EJ,Deane JE,Luzio JP,Owen DJ

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion.
Traffic (Copenhagen, Denmark)14(2)219-32(2013 Feb)
Pols MS,ten Brink C,Gosavi P,Oorschot V,Klumperman J

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.
Molecular biology of the cell22(10)1699-715(2011 May)
Zlatic SA,Tornieri K,L'Hernault SW,Faundez V