Taok3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Taok3
Entrez Gene ID	304530
Full Name	TAO kinase 3
Synonyms	JIK
General protein information	Preferred Names TAO kinase 3 Names serine/threonine-protein kinase TAO3 JNK/SAPK-inhibitory kinase axotomy-related gene 357 protein jun kinase-inhibitory kinase thousand and one amino acid protein 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024254.1	NP_001019425.1	serine/threonine-protein kinase TAO3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TAOK3	XP_509414.4
Mus musculus (house mouse)	Taok3	NP_001074777.1
Rattus norvegicus (Norway rat)	Taok3	NP_001019425.1
Gallus gallus (chicken)	TAOK3	NP_001012541.1
Canis lupus familiaris (dog)	TAOK3	XP_862617.2
Danio rerio (zebrafish)	taok3a	XP_001922665.3
Homo sapiens (human)	TAOK3	NP_057365.3
Bos taurus (cattle)	TAOK3	NP_001192987.1

Gene Ontology
Bibliography

Related articles in PubMed

TAO kinases mediate activation of p38 in response to DNA damage.
Raman M, Earnest S, Zhang K, Zhao Y, Cobb MH
The EMBO journal26(8)2005-14(2007 Apr)

JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells.
Wakabayashi T, Kosaka J, Oshika T
Journal of neurochemistry95(2)526-36(2005 Oct)

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M
The Journal of biological chemistry276(17)13935-40(2001 Apr)

Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways.
Zhang W, Chen T, Wan T, He L, Li N, Yuan Z, Cao X
Biochemical and biophysical research communications274(3)872-9(2000 Aug)

Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor.
Tassi E, Biesova Z, Di Fiore PP, Gutkind JS, Wong WT
The Journal of biological chemistry274(47)33287-95(1999 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

JIK may contribute to axotomy-induced retinal ganglion cell death by up-regulating the expression of BH3-only protein
Title: JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells.

The following Taok3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Taok3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06086	NM_001024254.1 Latest version!	Rattus norvegicus TAO kinase 3 (Taok3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$531.30 $759.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Taok3 ( NM_001024254.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019425.1 Rattus norvegicus TAO kinase 3 (Taok3), mRNA.

Price & Availability↑

CloneID	ORa06086
Clone ID Related Accession (Same CDS sequence)	NM_001024254.1
Accession Version	NM_001024254.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2697bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase TAO3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB195232.1. On May 27, 2005 this sequence version replaced XM_222216.3. ##Evidence-Data-START## Transcript exon combination :: AB195232.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCGTAAAG GAGTGCTGAA GGACCCCGAG ATTGCCGAGC TGTTCTTCAA GGAGGACCCC 
GAAGAGCTCT TTATCGACCT GCATGAAATC GGACATGGCA GCTTTGGAGC CGTGTACTTC 
GCAACTAATG CGCACACCAA CGAGGTGGTT GCTATTAAGA AAATGTCCTA CAGTGGGAAG 
CAGACCCACG AGAAATGGCA AGATATCCTG AAGGAAGTTC GATTCCTCCA GCAGCTGAAG 
CACCCGAACA CCATCGAGTA CAAAGGCTGT TATTTAAAGG AGCACACCGC TTGGTTGGTG 
ATGGAGTACT GCTTAGGTTC AGCCTCTGAC TTGTTAGAAG TTCATAAGAA ACCACTTCAG 
GAAGTAGAGA TTGCTGCTAT CACCCATGGT GCCTTGCAGG GGCTGGCCTA CCTCCACTTT 
CACTCCCTGA TTCACAGGGA CATTAAAGCA GGGAATATCC TCCTCACAGA GCCAGGCCAG 
GTGAAGCTGG CTGACTTCGG GTCCGCTTCC ATGGCTTCTC CTGCCAACTC CTTCGTGGGG 
ACTCCTTACT GGATGGCCCC AGAGGTGATC TTAGCCATGG ACGAAGGGCA GTACGACGGG 
AAAGTTGACA TCTGGTCACT CGGCATCACC TGCATAGAGC TGGCGGAGCG GAAGCCCCCC 
CTCTTCAACA TGAACGCCAT GAGCGCCCTC TACCACATCG CTCAGAATGA CTCCCCCACG 
CTGCAGTCCA GAGAATGGAC AGACTCCTTC AGGAGATTCG TTGATTACTG CTTGCACAAA 
ATACCTCAGG AACGACCAGC CGCGGCGGAA CTGTTGCGGC ACGACTTCAT TCGGAGGGAG 
CGGCCGCCGA GGGTCCTCAT TGACCTCATA CAGAGGACGA AAGATGCTGT CCGAGAGCTG 
GACAACCTGC AGTACAGGAA AATGAAGAAG ATCCTCTTCC AGGAGACTCG GAACGGACCC 
CTGAATGAGT CACAAGAAGA GGAAGAAGAC AGTGAGCAAG GAAGCAACCT GAACCGAGAG 
GTGGACAGTC TGGGGAGCAT CCACTCCATC CCCAGCGTGT CAGTGAGCAC GGGCAGCCGG 
AGCAGCAGCG TGAACAGCAT GCAGGAGGTC ATGGACGAGG GCAGCCCTGA GCTCGTCATG 
ATGCAGGAGG ATGAAGGCAC AGTCAACTCC AGCTCCTCTA TGGTACACAA GAAGGATCAT 
GTATTCGTAA GGGATGAGGC GGGCCACGGC GATCCCAGGC CTGAGCCGCG GCCTACCCAG 
TCAGTTCAGA GCCGGGCCCT CCACTATCGG AACCGAGAGC GCTTTGCCAC GATCAAATCC 
GCGTCTTTGG TTACACGGCA GATCCACGAG CATGAGCAGG AGAACGAGCT GCGGGAACAG 
ATGTCAGGTT ATAAGCGGAT GCGGCGCCAG CACCAGAAGC AGCTGATCGC CCTGGAGAAC 
AAGCTGAAGG CTGAGATGGA TGAGCACCGC CTCAAGCTCC AGAAGGAGGT GGAGACGCAT 
GCCAACAACT CGTCCATCGA GCTGGAGAAG CTGGCCAAGA AGCAAGTGGC TACCATAGAA 
AAGGAGGCAA AGGTAGCCGC AGCGGATGAG AAGAAGTTCC AGCAGCAGAT CCTGGCCCAG 
CAGAAGAAGG ACTTGACAAC TTTCTTAGAA AGTCAGAAGA AGCAGTACAA GATTTGTAAG 
GAGAAAATAA AAGAGGAAAT GAACGAGGAC CATAGCACAC CCAAGAAGGA GAAGCAGGAG 
CGCATATCGA AGCATAAAGA GAACCTGCAG CACACGCAGG CCGAGGAGGA AGCCCACCTG 
CTCACGCAAC AGAGGCTGTA CTACGACAGA AACTGCCGCT GCTTCAAGCG GAAAATAATG 
ACCAAGCGCC ACGAGGTGGA ACAGCAGAAC ATTCGGGAGG AACTAAATAA AAAGAGGACC 
CAGAAAGAAA TGGAGCACGC CATGCTGATC CGGCATGATG AATCCACCCG AGAGCTCGAG 
TACAGACAGC TGCACACACT GCAGAAGCTC CGCATGGACC TGATCCGGTT ACAGCACCAG 
ACTGAGCTGG AGAACCAGCT GGAGTACAAT AAGAGGCGGG AGCGGGAGCT GCACCGGAAG 
CACGTCATGG AGCTTCGGCA ACAGCCGAAA AACTTAAAGG CCATGGAAAT GCAAATTAAA 
AAGCAGTTTC AGGACACTTG CAAAGTACAG ACCAAACAGT ACAAAGCACT CAAAAACCAC 
CAGTTGGAAG TCACTCCAAA GAATGAGCAC AAAGCAATCC TAAAGACACT GAAGGAGGAG 
CAGACGAGGA AGCTGGCCAT CTTGGCCGAG CAGTATGAAC AGAGTATAAA CGAGATGATG 
GCCTCTCAAG CGTTACGGCT AGACGAGGCG CAAGAGGCAG AATGCCAGGC CTTGAGACTA 
CAGCTCCAGC AGGAGATGGA GCTGCTCAAC GCCTACCAGA GCAAAATCAA GATGCAAACG 
GAGGCCCAGC ACGAGCGCGA GCTGCAGAAG CTAGAGCAGA GGGTGTCCCT GCGCAGAGCG 
CATCTTGAGC AGAAGATTGA AGAGGAGCTG GCCGCCCTGC AGAAGGAACG CAGTGAGAGG 
ATCAAGACTC TCCTGGAAAG ACAAGAGCGA GAGACCGAGA CTTTTGACAT GGAGAGCCTC 
AGAATGGGGT TTGGGAATTT GGTGACATTA GATTTTCCTA AGGAGGACTA TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019425.1
CDS	116..2812
Translation	MRKGVLKDPEIAELFFKEDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVRFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQERPAAAELLRHDFIRRERPPRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEEEEDSEQGSNLNREVDSLGSIHSIPSVSVSTGSRSSSVNSMQEVMDEGSPELVMMQEDEGTVNSSSSMVHKKDHVFVRDEAGHGDPRPEPRPTQSVQSRALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVATIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDRNCRCFKRKIMTKRHEVEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKAILKTLKEEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKTLLERQERETETFDMESLRMGFGNLVTLDFPKEDYR

Target ORF information:

RefSeq Version	NM_001024254.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAO kinase 3 (Taok3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024254.1

ORF Insert Sequence:

ATGCGTAAAG GAGTGCTGAA GGACCCCGAG ATTGCCGAGC TGTTCTTCAA GGAGGACCCC 
GAAGAGCTCT TTATCGACCT GCATGAAATC GGACATGGCA GCTTTGGAGC CGTGTACTTC 
GCAACTAATG CGCACACCAA CGAGGTGGTT GCTATTAAGA AAATGTCCTA CAGTGGGAAG 
CAGACCCACG AGAAATGGCA AGATATCCTG AAGGAAGTTC GATTCCTCCA GCAGCTGAAG 
CACCCGAACA CCATCGAGTA CAAAGGCTGT TATTTAAAGG AGCACACCGC TTGGTTGGTG 
ATGGAGTACT GCTTAGGTTC AGCCTCTGAC TTGTTAGAAG TTCATAAGAA ACCACTTCAG 
GAAGTAGAGA TTGCTGCTAT CACCCATGGT GCCTTGCAGG GGCTGGCCTA CCTCCACTTT 
CACTCCCTGA TTCACAGGGA CATTAAAGCA GGGAATATCC TCCTCACAGA GCCAGGCCAG 
GTGAAGCTGG CTGACTTCGG GTCCGCTTCC ATGGCTTCTC CTGCCAACTC CTTCGTGGGG 
ACTCCTTACT GGATGGCCCC AGAGGTGATC TTAGCCATGG ACGAAGGGCA GTACGACGGG 
AAAGTTGACA TCTGGTCACT CGGCATCACC TGCATAGAGC TGGCGGAGCG GAAGCCCCCC 
CTCTTCAACA TGAACGCCAT GAGCGCCCTC TACCACATCG CTCAGAATGA CTCCCCCACG 
CTGCAGTCCA GAGAATGGAC AGACTCCTTC AGGAGATTCG TTGATTACTG CTTGCACAAA 
ATACCTCAGG AACGACCAGC CGCGGCGGAA CTGTTGCGGC ACGACTTCAT TCGGAGGGAG 
CGGCCGCCGA GGGTCCTCAT TGACCTCATA CAGAGGACGA AAGATGCTGT CCGAGAGCTG 
GACAACCTGC AGTACAGGAA AATGAAGAAG ATCCTCTTCC AGGAGACTCG GAACGGACCC 
CTGAATGAGT CACAAGAAGA GGAAGAAGAC AGTGAGCAAG GAAGCAACCT GAACCGAGAG 
GTGGACAGTC TGGGGAGCAT CCACTCCATC CCCAGCGTGT CAGTGAGCAC GGGCAGCCGG 
AGCAGCAGCG TGAACAGCAT GCAGGAGGTC ATGGACGAGG GCAGCCCTGA GCTCGTCATG 
ATGCAGGAGG ATGAAGGCAC AGTCAACTCC AGCTCCTCTA TGGTACACAA GAAGGATCAT 
GTATTCGTAA GGGATGAGGC GGGCCACGGC GATCCCAGGC CTGAGCCGCG GCCTACCCAG 
TCAGTTCAGA GCCGGGCCCT CCACTATCGG AACCGAGAGC GCTTTGCCAC GATCAAATCC 
GCGTCTTTGG TTACACGGCA GATCCACGAG CATGAGCAGG AGAACGAGCT GCGGGAACAG 
ATGTCAGGTT ATAAGCGGAT GCGGCGCCAG CACCAGAAGC AGCTGATCGC CCTGGAGAAC 
AAGCTGAAGG CTGAGATGGA TGAGCACCGC CTCAAGCTCC AGAAGGAGGT GGAGACGCAT 
GCCAACAACT CGTCCATCGA GCTGGAGAAG CTGGCCAAGA AGCAAGTGGC TACCATAGAA 
AAGGAGGCAA AGGTAGCCGC AGCGGATGAG AAGAAGTTCC AGCAGCAGAT CCTGGCCCAG 
CAGAAGAAGG ACTTGACAAC TTTCTTAGAA AGTCAGAAGA AGCAGTACAA GATTTGTAAG 
GAGAAAATAA AAGAGGAAAT GAACGAGGAC CATAGCACAC CCAAGAAGGA GAAGCAGGAG 
CGCATATCGA AGCATAAAGA GAACCTGCAG CACACGCAGG CCGAGGAGGA AGCCCACCTG 
CTCACGCAAC AGAGGCTGTA CTACGACAGA AACTGCCGCT GCTTCAAGCG GAAAATAATG 
ACCAAGCGCC ACGAGGTGGA ACAGCAGAAC ATTCGGGAGG AACTAAATAA AAAGAGGACC 
CAGAAAGAAA TGGAGCACGC CATGCTGATC CGGCATGATG AATCCACCCG AGAGCTCGAG 
TACAGACAGC TGCACACACT GCAGAAGCTC CGCATGGACC TGATCCGGTT ACAGCACCAG 
ACTGAGCTGG AGAACCAGCT GGAGTACAAT AAGAGGCGGG AGCGGGAGCT GCACCGGAAG 
CACGTCATGG AGCTTCGGCA ACAGCCGAAA AACTTAAAGG CCATGGAAAT GCAAATTAAA 
AAGCAGTTTC AGGACACTTG CAAAGTACAG ACCAAACAGT ACAAAGCACT CAAAAACCAC 
CAGTTGGAAG TCACTCCAAA GAATGAGCAC AAAGCAATCC TAAAGACACT GAAGGAGGAG 
CAGACGAGGA AGCTGGCCAT CTTGGCCGAG CAGTATGAAC AGAGTATAAA CGAGATGATG 
GCCTCTCAAG CGTTACGGCT AGACGAGGCG CAAGAGGCAG AATGCCAGGC CTTGAGACTA 
CAGCTCCAGC AGGAGATGGA GCTGCTCAAC GCCTACCAGA GCAAAATCAA GATGCAAACG 
GAGGCCCAGC ACGAGCGCGA GCTGCAGAAG CTAGAGCAGA GGGTGTCCCT GCGCAGAGCG 
CATCTTGAGC AGAAGATTGA AGAGGAGCTG GCCGCCCTGC AGAAGGAACG CAGTGAGAGG 
ATCAAGACTC TCCTGGAAAG ACAAGAGCGA GAGACCGAGA CTTTTGACAT GGAGAGCCTC 
AGAATGGGGT TTGGGAATTT GGTGACATTA GATTTTCCTA AGGAGGACTA TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TAO kinases mediate activation of p38 in response to DNA damage.
The EMBO journal26(8)2005-14(2007 Apr)
Raman M,Earnest S,Zhang K,Zhao Y,Cobb MH

JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells.
Journal of neurochemistry95(2)526-36(2005 Oct)
Wakabayashi T,Kosaka J,Oshika T

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
The Journal of biological chemistry276(17)13935-40(2001 Apr)
Yoneda T,Imaizumi K,Oono K,Yui D,Gomi F,Katayama T,Tohyama M

Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways.
Biochemical and biophysical research communications274(3)872-9(2000 Aug)
Zhang W,Chen T,Wan T,He L,Li N,Yuan Z,Cao X

Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor.
The Journal of biological chemistry274(47)33287-95(1999 Nov)
Tassi E,Biesova Z,Di Fiore PP,Gutkind JS,Wong WT

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Taok3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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