Pik3r2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pik3r2
Entrez Gene ID	29741
Full Name	phosphoinositide-3-kinase regulatory subunit 2
General protein information	Preferred Names phosphoinositide-3-kinase regulatory subunit 2 Names phosphatidylinositol 3-kinase regulatory subunit beta PI3-kinase p85 subunit beta PI3-kinase regulatory subunit beta PI3-kinase subunit p85-beta PI3K regulatory subunit beta phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) phosphoinositide-3-kinase, regulatory subunit 2 (beta) ptdIns-3-kinase p85-beta ptdIns-3-kinase regulatory subunit beta ptdIns-3-kinase regulatory subunit p85-beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16p14
Summary	regulatory subunit of the enzyme phosphatidylinositol 3-kinase; involved in cellular signaling mechanisms [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017600073.1	XP_017455562.1	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
NM_022185.2	NP_071521.2	phosphatidylinositol 3-kinase regulatory subunit beta
XM_017600072.1	XP_017455561.1	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
XM_017600071.1	XP_017455560.1	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PIK3R2	XP_512509.2
Gallus gallus (chicken)	PIK3R2	XP_001233341.3
Xenopus tropicalis (tropical clawed frog)	pik3r2	XP_002934855.2
Homo sapiens (human)	PIK3R2	NP_005018.1
	PIK3R2	XP_001114094.1
Danio rerio (zebrafish)	pik3r2	NP_997987.1
Canis lupus familiaris (dog)	PIK3R2	XP_852406.2
Rattus norvegicus (Norway rat)	Pik3r2	NP_071521.2
Bos taurus (cattle)	PIK3R2	NP_777001.1
Mus musculus (house mouse)	Pik3r2	NP_032867.2

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA-126-3p attenuates blood-brain barrier disruption, cerebral edema and neuronal injury following intracerebral hemorrhage by regulating PIK3R2 and Akt.
Xi T, Jin F, Zhu Y, Wang J, Tang L, Wang Y, Liebeskind DS, He Z
Biochemical and biophysical research communications494(1-2)144-151(2017 12)

MicroRNA?126 inhibits proliferation and metastasis by targeting pik3r2 in prostate cancer.
Song L, Xie X, Yu S, Peng F, Peng L
Molecular medicine reports13(2)1204-10(2016 Feb)

Upregulation of MicroRNA-126 Contributes to Endothelial Progenitor Cell Function in Deep Vein Thrombosis via Its Target PIK3R2.
Meng Q, Wang W, Yu X, Li W, Kong L, Qian A, Li C, Li X
Journal of cellular biochemistry116(8)1613-23(2015 Aug)

Phosphoinositide 3-kinase p85beta regulates invadopodium formation.
Cariaga-Mart?nez AE, Cort?s I, Garc?a E, P?rez-Garc?a V, Pajares MJ, Idoate MA, Redondo-Mu??z J, Ant?n IM, Carrera AC
Biology open3(10)924-36(2014 Sep)

microRNA 126 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PIK3R2-PI3K/Akt signalling pathway.
Zhang J, Zhang Z, Zhang DY, Zhu J, Zhang T, Wang C
PloS one8(12)e83294(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

in vitro assays confirmed upregulation of PIK3R2 upon knockdown of miR-126-3p in brain microvascular endothelial cells (BMECs), and silencing of miR-126-3p resulted in impaired BMEC barrier permeability and reversed vascular endothelial growth factor- and angiopoietin-1-induced activation of Akt and inhibition of BMEC apoptosis
Title: MicroRNA-126-3p attenuates blood-brain barrier disruption, cerebral edema and neuronal injury following intracerebral hemorrhage by regulating PIK3R2 and Akt.

Findings demonstrated that miR-126 promoted endothelial progenitor cells function through suppressing PIK3R2 expression
Title: Upregulation of MicroRNA-126 Contributes to Endothelial Progenitor Cell Function in Deep Vein Thrombosis via Its Target PIK3R2.

These results show that miR-126 targets PIK3R2 to inhibit EPC EndMT and that this process involves regulation of the PI3K/Akt signalling pathway.
Title: microRNA 126 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PIK3R2-PI3K/Akt signalling pathway.

The following Pik3r2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pik3r2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05381	NM_022185.2 Latest version!	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa05381	XM_017600072.1 Latest version!	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa05381	XM_017600073.1 Latest version!	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa05381	XM_017600071.1 Latest version!	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pik3r2 ( NM_022185.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071521.2 Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), mRNA.

Price & Availability↑

CloneID	ORa05381
Clone ID Related Accession (Same CDS sequence)	XM_017600073.1 , NM_022185.2 , XM_017600072.1 , XM_017600071.1
Accession Version	NM_022185.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3-kinase regulatory subunit beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC089805.1. On Feb 13, 2005 this sequence version replaced NM_022185.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071521.2
CDS	441..2609
Translation	MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPSESGHTLASLAEQFSPPEPAPPILVKLIEAIEQAELDSECYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLALPAAVVTPEAASEAYRAMREVTGPVGLVLEPPTLPLHQALTLQFLLQHLGRVARRAPSPATAVHALASAFGPLLLRAPPPGGEGDGSEPAPDFPVLLLERLVQEHVDEQDTAPPALPPKPSKVKPAPTALANGGSTPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVSKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYSLMEDEDALPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR

Target ORF information:

RefSeq Version	NM_022185.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022185.2

ORF Insert Sequence:

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pik3r2 ( XM_017600073.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455562.1 Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa05381
Clone ID Related Accession (Same CDS sequence)	XM_017600073.1 , NM_022185.2 , XM_017600072.1 , XM_017600071.1
Accession Version	XM_017600073.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455562.1
CDS	1835..4003
Translation	MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPSESGHTLASLAEQFSPPEPAPPILVKLIEAIEQAELDSECYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLALPAAVVTPEAASEAYRAMREVTGPVGLVLEPPTLPLHQALTLQFLLQHLGRVARRAPSPATAVHALASAFGPLLLRAPPPGGEGDGSEPAPDFPVLLLERLVQEHVDEQDTAPPALPPKPSKVKPAPTALANGGSTPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVSKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYSLMEDEDALPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR

Target ORF information:

RefSeq Version	XM_017600073.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600073.1

ORF Insert Sequence:

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pik3r2 ( XM_017600072.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455561.1 Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa05381
Clone ID Related Accession (Same CDS sequence)	XM_017600073.1 , NM_022185.2 , XM_017600072.1 , XM_017600071.1
Accession Version	XM_017600072.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455561.1
CDS	1341..3509
Translation	MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPSESGHTLASLAEQFSPPEPAPPILVKLIEAIEQAELDSECYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLALPAAVVTPEAASEAYRAMREVTGPVGLVLEPPTLPLHQALTLQFLLQHLGRVARRAPSPATAVHALASAFGPLLLRAPPPGGEGDGSEPAPDFPVLLLERLVQEHVDEQDTAPPALPPKPSKVKPAPTALANGGSTPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVSKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYSLMEDEDALPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR

Target ORF information:

RefSeq Version	XM_017600072.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600072.1

ORF Insert Sequence:

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pik3r2 ( XM_017600071.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455560.1 Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05381
Clone ID Related Accession (Same CDS sequence)	XM_017600073.1 , NM_022185.2 , XM_017600072.1 , XM_017600071.1
Accession Version	XM_017600071.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455560.1
CDS	2095..4263
Translation	MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPSESGHTLASLAEQFSPPEPAPPILVKLIEAIEQAELDSECYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLALPAAVVTPEAASEAYRAMREVTGPVGLVLEPPTLPLHQALTLQFLLQHLGRVARRAPSPATAVHALASAFGPLLLRAPPPGGEGDGSEPAPDFPVLLLERLVQEHVDEQDTAPPALPPKPSKVKPAPTALANGGSTPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVSKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYSLMEDEDALPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR

Target ORF information:

RefSeq Version	XM_017600071.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600071.1

ORF Insert Sequence:

ATGGCAGGTG CTGAAGGCTT CCAGTACAGG GCTGTATACC CATTCCGCCG GGAGCGGCCT 
GAGGACCTGG AGCTTCTTCC TGGTGACCTC CTGGTGGTGA GCCGGGTGGC TCTGCAGGCA 
CTAGGTGTGG CTGATGGAGG AGAGCGCTGC CCACACAACG TGGGCTGGAT GCCTGGCTTC 
AATGAGCGCA CCCGACAGCG AGGGGACTTC CCTGGAACAT ATGTGGAGTT CCTAGGACCT 
GTGGCTCTGG CTCGACCAGG CCCTCGCCCA CGGGGGCCCC GTCCGTTGCC TGCCAGGCCC 
TTGGATGGAC CTTCTGAGTC AGGTCACACA CTGGCAAGCC TGGCAGAGCA GTTCTCCCCA 
CCTGAGCCTG CGCCCCCGAT TCTGGTGAAG CTGATAGAAG CCATTGAGCA AGCAGAGCTG 
GACAGTGAAT GCTACAGTAG GCCGGAGCTG CCCGCACCAC GGACAGACTG GTCCCTGAGT 
GACTTGGAGC AGTGGGACCG CACCACCTTG TACGATGCTG TTAAGGGCTT CCTGCTGGCA 
TTGCCTGCAG CTGTGGTGAC TCCTGAGGCT GCATCGGAGG CTTATCGGGC GATGCGGGAG 
GTTACGGGGC CTGTGGGGCT GGTGCTGGAA CCCCCAACGC TGCCGTTGCA CCAGGCCCTC 
ACTCTGCAGT TCCTGCTGCA GCACCTGGGC CGCGTGGCCC GCAGAGCACC CTCACCAGCT 
ACAGCTGTCC ACGCACTGGC CAGTGCCTTC GGGCCGCTGC TGCTGCGTGC GCCTCCGCCA 
GGGGGCGAGG GTGATGGGAG TGAGCCTGCA CCTGACTTCC CTGTGCTGCT TCTAGAGAGG 
CTGGTGCAGG AGCATGTGGA TGAGCAAGAC ACCGCCCCGC CAGCACTGCC ACCCAAACCC 
TCTAAGGTAA AGCCGGCACC CACAGCCCTG GCCAATGGAG GGAGTACACC CTCGCTTCAG 
GATGCAGAGT GGTACTGGGG GGACATTTCC AGGGAAGAGG TGAATGAGAG GCTCCGAGAC 
ACACCTGATG GTACCTTCTT AGTCCGAGAT GCATCCAGCA AGATCCAAGG AGAGTACACG 
CTCACCCTCA GGAAAGGCGG GAACAACAAG CTAATCAAAG TCTTCCACCG GGACGGTCAC 
TATGGCTTCT CAGAGCCCCT TACCTTCTGC TCCGTGGTAG AGCTCATCTC CCACTACCGA 
CATGAGTCAC TGGCCCAGTA CAACGCCAAG CTGGACACGC GCCTTCTCTA CCCTGTGTCC 
AAGTACCAGC AAGACCAGGT GGTGAAGGAG GACAGTGTAG AGGCTGTGGG TGCCCAGCTC 
AAGGTCTACC ACCAGCAGTA CCAGGACAAG AGCCGCGAGT ATGACCAGCT CTATGAGGAA 
TACACACGAA CCTCCCAGGA GCTTCAGATG AAGCGCACAG CCATAGAGGC CTTCAACGAG 
ACCATCAAGA TCTTCGAAGA ACAGGGCCAG ACACAGGAAA AGTGCAGCAA GGAGTATTTG 
GAGCGCTTCC GGCGAGAGGG CAATGAGAAG GAGATGCAGA GGATCCTGCT GAACTCGGAG 
CGACTCAAGT CTCGAATCGC GGAGATACAT GAAAGCCGCA CGAAGCTGGA GCAGGATCTG 
CGGGCGCAGG CCTCGGACAA TCGAGAGATT GACAAGCGCA TGAACAGCCT CAAGCCTGAT 
CTCATGCAGC TGCGCAAGAT CAGGGACCAG TACCTCGTGT GGCTCACCCA GAAAGGTGCC 
CGACAGAGGA AGATCAACGA GTGGCTGGGA ATCAAGAATG AGACTGAGGA CCAGTATTCA 
CTGATGGAGG ATGAGGACGC CCTCCCCCAC CATGAGGAGC GCACGTGGTA CGTGGGCAAG 
ATCAACCGCA CACAGGCGGA GGAGATGCTG AGTGGCAAAC GAGACGGGAC CTTCCTCATC 
CGGGAGAGCA GCCAGCGGGG CTGTTACGCA TGCTCTGTGG TGGTGGATGG CGACACGAAG 
CACTGTGTCA TCTACCGCAC AGCCACTGGC TTTGGCTTCG CAGAGCCCTA TAACCTGTAC 
GGATCCCTGA AGGAGCTGGT ATTGCACTAC CAGCACGCAT CACTTGTGCA GCACAATGAC 
GCGCTCACCG TCACCCTCGC ACACCCTGTG CGTGCCCCCG GGCCTGGCCC GCCCCCTGCA 
GCACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA-126-3p attenuates blood-brain barrier disruption, cerebral edema and neuronal injury following intracerebral hemorrhage by regulating PIK3R2 and Akt.
Biochemical and biophysical research communications494(1-2)144-151(2017 12)
Xi T,Jin F,Zhu Y,Wang J,Tang L,Wang Y,Liebeskind DS,He Z

MicroRNA?126 inhibits proliferation and metastasis by targeting pik3r2 in prostate cancer.
Molecular medicine reports13(2)1204-10(2016 Feb)
Song L,Xie X,Yu S,Peng F,Peng L

Upregulation of MicroRNA-126 Contributes to Endothelial Progenitor Cell Function in Deep Vein Thrombosis via Its Target PIK3R2.
Journal of cellular biochemistry116(8)1613-23(2015 Aug)
Meng Q,Wang W,Yu X,Li W,Kong L,Qian A,Li C,Li X

Phosphoinositide 3-kinase p85beta regulates invadopodium formation.
Biology open3(10)924-36(2014 Sep)
Cariaga-Mart?nez AE,Cort?s I,Garc?a E,P?rez-Garc?a V,Pajares MJ,Idoate MA,Redondo-Mu??z J,Ant?n IM,Carrera AC

microRNA 126 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PIK3R2-PI3K/Akt signalling pathway.
PloS one8(12)e83294(2013)
Zhang J,Zhang Z,Zhang DY,Zhu J,Zhang T,Wang C

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Pik3r2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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