Mcm4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mcm4
Entrez Gene ID	29728
Full Name	minichromosome maintenance complex component 4
Synonyms	Mcmd4
General protein information	Preferred Names minichromosome maintenance complex component 4 Names DNA replication licensing factor MCM4 mini chromosome maintenance deficient 4 homolog minichromosome maintenance deficient 4 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q23
Summary	replication licensing factor; homolog of yeast CDC21 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_033651.1	NP_387500.1	DNA replication licensing factor MCM4

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	MCM4	XP_424376.2
Arabidopsis thaliana (thale cress)	MCM4	NP_179236.3
Pan troglodytes (chimpanzee)	MCM4	XP_528129.2
Canis lupus familiaris (dog)	MCM4	XP_535063.3
Mus musculus (house mouse)	Mcm4	NP_032591.3
Rattus norvegicus (Norway rat)	Mcm4	NP_387500.1
Eremothecium gossypii	AGOS_ADL026W	NP_984071.2
Magnaporthe oryzae (rice blast fungus)	MGG_09293	XP_003709942.1
Xenopus tropicalis (tropical clawed frog)	mcm4	NP_001005655.1
Bos taurus (cattle)	MCM4	NP_001068626.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004956	XP_315054.2
Homo sapiens (human)	MCM4	NP_005905.2
	MCM4	XP_002805376.1
Danio rerio (zebrafish)	mcm4	NP_944595.2
Schizosaccharomyces pombe (fission yeast)	mcm4	NP_588004.2
Drosophila melanogaster (fruit fly)	dpa	NP_477185.1
Caenorhabditis elegans (roundworm)	mcm-4	NP_490962.1
Saccharomyces cerevisiae (baker's yeast)	MCM4	NP_015344.1
Kluyveromyces lactis	KLLA0C17512g	XP_452982.1
Neurospora crassa	NCU02539	XP_965670.1

Gene Ontology
Bibliography

Related articles in PubMed

Peroxisome proliferator-activated receptor ? coactivator 1? (PGC-1?) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.
Guo Y, Fan Y, Zhang J, Chang L, Lin JD, Chen YE
The Journal of biological chemistry288(7)4625-36(2013 Feb)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Purification of proteins associated with specific genomic Loci.
D?jardin J, Kingston RE
Cell136(1)175-86(2009 Jan)

Identification and characterization of a novel component of the human minichromosome maintenance complex.
Sakwe AM, Nguyen T, Athanasopoulos V, Shire K, Frappier L
Molecular and cellular biology27(8)3044-55(2007 Apr)

DNA binding and helicase actions of mouse MCM4/6/7 helicase.
You Z, Masai H
Nucleic acids research33(9)3033-47(2005)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells
Title: Peroxisome proliferator-activated receptor ? coactivator 1? (PGC-1?) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.

The following Mcm4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09132	NM_033651.1 Latest version!	Rattus norvegicus minichromosome maintenance complex component 4 (Mcm4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mcm4 ( NM_033651.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_387500.1 Rattus norvegicus minichromosome maintenance complex component 4 (Mcm4), mRNA.

Price & Availability↑

CloneID	ORa09132
Clone ID Related Accession (Same CDS sequence)	NM_033651.1
Accession Version	NM_033651.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2589bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	DNA replication licensing factor MCM4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07034787.1. On or before Dec 13, 2009 this sequence version replaced XM_001068436.1, XM_344048.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FQ226176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGTCCC CGGCATCCAC CCCAAGTCGC CGCAGCAGCC GACGCGGACG AGTCACCCCA 
ACCCAGTCGC TTCGAAGTGA GGAAAGCCGA TCATCTCCCA GTGGGAGACG TAGAGGCGAA 
GATTCTTCCA CCGGAGAGTT GCTGCCAATG CCCACCTCAC CAGGAGCAGA CCTGCAGAGC 
CCAGCTGCAC AGAATGCCTT GTTTTCCAGC CCTCCTCAGA TGCATTCTTC AGCTATTCCT 
TTGGAATTTG ATGTTAGTTC GCCATTGACA TATGGCACTC CCAGCTCTCG AGTGGAAGGA 
ACCCCAAGAA GTGGGGTGAG AGGCACACCC ATGAGGCAGA GGCCAGACCT GGGCTCAGCA 
CGAAAGGGTT TGCAGGTGGA TCTGCAGTCT GACGGAGCAG CAGCAGAAGA CACAGTAGCA 
AGTGAACAGT CTCTAGGCCA AAAGCTTGTG ATTTGGGGAA CAGACGTGAA TGTGGCAACA 
TGCAAAGAAC ATTTTCAGAG ATTCCTTCAA TGTTTTACTG ATCCTCTGGC CAAAGAAGAA 
GAAAATGTTG GCATAGATAT TACGCAACCT TTGTACATGC AACGACTTGG AGAGATTAAT 
ATTACAGGAG AGCCATTTTT AAATGTGAAC TGTGAACACA TAAAATCATT TGGCAAAAAC 
TTGTATAGAC AGCTCATCTC CTACCCACAG GAGGTTATAC CAACCTTTGA CATGGCTGTC 
AATGAGATCT TCTTTGACCG TTATCCTGAC TCCATCTTAG AACATCAGAT TCAAGTCAGA 
CCTTTTAATG CATTGAAGAC AAAGAGTATG AGAAACTTGA ATCCAGAAGA CATTGATCAG 
CTCATCACCA TCAGTGGCAT GGTTATCAGA ACGTCACAGC TGATTCCCGA GATGCAGGAG 
GCCTTTTTCC AGTGCCAAGT CTGTGCCCAT ACCACCCGGG TAGAGATGGA CCGAGGCCGA 
ATTGCTGAGC CCTGCACTTG CGTACACTGC CACACTACCC ACAGTATGGC ACTGATCCAC 
AACCGTTCAC TATTCTCTGA CAAGCAGATG ATCAAGCTTC AAGAGTCTCC TGAAGATATG 
CCTGCTGGGC AGACACCTCA CACTGTTGTC CTTTTTGCCC ACAATGATCT TGTAGACAAG 
GTTCAGCCAG GGGACAGAGT GAATGTCACA GGCATATATC GAGCAGTACC TATTCGAGTT 
AATCCAAGAG TGAGCAACGT GAAGTCTGTC TATAAAACCC ACATTGATGT CATCCATTAT 
CGGAAAACGG ATGCAAAACG TCTGCATGGC CTTGATGAAG AAGCAGAACA GAAACTTTTT 
TCAGAGAAAC GTGTGAAATT GCTTAAGGAA CTTTCCAGGA AGCCAGATAT TTATGAGCGG 
CTTGCTTCAG CCTTGGCTCC CAGCATTTAT GAACATGAAG ATATAAAAAA GGGAATCCTA 
CTTCAACTCT TTGGTGGAAC AAGGAAGGAT TTCAGTCACA CTGGAAGGGG TAAATTCCGT 
GCTGAGATTA ACATCCTTCT GTGTGGTGAC CCTGGCACCA GCAAGTCCCA GCTGCTACAG 
TATGTATACA ACCTGGTTCC CAGAGGCCAG TACACATCTG GAAAAGGCTC CAGTGCAGTT 
GGCCTCACAG CCTATGTGAT GAAAGACCCT GAGACCAGGC AGCTTGTCCT CCAGACAGGT 
GCCCTTGTAC TGAGTGACAA TGGCATATGT TGCATTGATG AGTTTGACAA AATGAATGAA 
AGCACAAGGT CCGTGCTGCA TGAGGTCATG GAACAGCAGA CTCTGTCCAT TGCAAAGGCT 
GGGATCATCT GTCAGCTCAA TGCACGAACC TCTGTCCTGG CAGCAGCAAA CCCTATTGAG 
TCCCAGTGGA ACCCTAAAAA AACAACCATT GAAAATATCC AACTACCACA CACACTGTTG 
TCAAGGTTTG ATCTCATTTT CCTCATGCTA GACCCTCAAG ATGAGGCATA TGACCGACGC 
CTAGCCCACC ACCTGGTTTC ATTGTACTAC CAAAGTGAGG AGCAGGTGGA GCAGGAGTTC 
CTGGACATGG CAGTGCTGAA AGACTACATT GCCTATGCAC ATAGTACTAT CATGCCCCGG 
CTGAGTGAGG AGGCCAGCCA GGCTCTCATT GAGGCTTATG TAAACATGAG GAAGATCGGG 
AGTAGTCGGG GGATGGTTTC TGCTTACCCT CGACAGCTAG AGTCATTAAT TCGCTTAGCA 
GAAGCCCATG CTAAAGTAAG ATTTTCAGAC AAAGTTGAAG CAATCGATGT GGAAGAGGCA 
AAACGCCTTC ACCGGGAGGC TCTGAAGCAG TCTGCCACTG ACCCTCGCAC TGGCATTGTG 
GACATATCTA TTCTTACTAC AGGAATGAGT GCCACTTCTC GTAAACGGAA AGAAGAATTA 
GCTGAAGCAC TGAGAAAACT TATTTTATCT AAGGGTAAAA CACCAGCCTT AAAGTACCAA 
CAGCTATTTG AGGATATTCG GGGACAATCT GACACAGCAA TTACCAAGGA CATGTTTGAA 
GAGGCCCTGC GTGCTTTGGC TGATGATGAT TTCCTAACAG TGACTGGGAA GACTGTCCGC 
CTACTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_387500.1
CDS	194..2782
Translation	MSSPASTPSRRSSRRGRVTPTQSLRSEESRSSPSGRRRGEDSSTGELLPMPTSPGADLQSPAAQNALFSSPPQMHSSAIPLEFDVSSPLTYGTPSSRVEGTPRSGVRGTPMRQRPDLGSARKGLQVDLQSDGAAAEDTVASEQSLGQKLVIWGTDVNVATCKEHFQRFLQCFTDPLAKEEENVGIDITQPLYMQRLGEINITGEPFLNVNCEHIKSFGKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPCTCVHCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQVEQEFLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSDKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQLFEDIRGQSDTAITKDMFEEALRALADDDFLTVTGKTVRLL

Target ORF information:

RefSeq Version	NM_033651.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus minichromosome maintenance complex component 4 (Mcm4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033651.1

ORF Insert Sequence:

ATGTCGTCCC CGGCATCCAC CCCAAGTCGC CGCAGCAGCC GACGCGGACG AGTCACCCCA 
ACCCAGTCGC TTCGAAGTGA GGAAAGCCGA TCATCTCCCA GTGGGAGACG TAGAGGCGAA 
GATTCTTCCA CCGGAGAGTT GCTGCCAATG CCCACCTCAC CAGGAGCAGA CCTGCAGAGC 
CCAGCTGCAC AGAATGCCTT GTTTTCCAGC CCTCCTCAGA TGCATTCTTC AGCTATTCCT 
TTGGAATTTG ATGTTAGTTC GCCATTGACA TATGGCACTC CCAGCTCTCG AGTGGAAGGA 
ACCCCAAGAA GTGGGGTGAG AGGCACACCC ATGAGGCAGA GGCCAGACCT GGGCTCAGCA 
CGAAAGGGTT TGCAGGTGGA TCTGCAGTCT GACGGAGCAG CAGCAGAAGA CACAGTAGCA 
AGTGAACAGT CTCTAGGCCA AAAGCTTGTG ATTTGGGGAA CAGACGTGAA TGTGGCAACA 
TGCAAAGAAC ATTTTCAGAG ATTCCTTCAA TGTTTTACTG ATCCTCTGGC CAAAGAAGAA 
GAAAATGTTG GCATAGATAT TACGCAACCT TTGTACATGC AACGACTTGG AGAGATTAAT 
ATTACAGGAG AGCCATTTTT AAATGTGAAC TGTGAACACA TAAAATCATT TGGCAAAAAC 
TTGTATAGAC AGCTCATCTC CTACCCACAG GAGGTTATAC CAACCTTTGA CATGGCTGTC 
AATGAGATCT TCTTTGACCG TTATCCTGAC TCCATCTTAG AACATCAGAT TCAAGTCAGA 
CCTTTTAATG CATTGAAGAC AAAGAGTATG AGAAACTTGA ATCCAGAAGA CATTGATCAG 
CTCATCACCA TCAGTGGCAT GGTTATCAGA ACGTCACAGC TGATTCCCGA GATGCAGGAG 
GCCTTTTTCC AGTGCCAAGT CTGTGCCCAT ACCACCCGGG TAGAGATGGA CCGAGGCCGA 
ATTGCTGAGC CCTGCACTTG CGTACACTGC CACACTACCC ACAGTATGGC ACTGATCCAC 
AACCGTTCAC TATTCTCTGA CAAGCAGATG ATCAAGCTTC AAGAGTCTCC TGAAGATATG 
CCTGCTGGGC AGACACCTCA CACTGTTGTC CTTTTTGCCC ACAATGATCT TGTAGACAAG 
GTTCAGCCAG GGGACAGAGT GAATGTCACA GGCATATATC GAGCAGTACC TATTCGAGTT 
AATCCAAGAG TGAGCAACGT GAAGTCTGTC TATAAAACCC ACATTGATGT CATCCATTAT 
CGGAAAACGG ATGCAAAACG TCTGCATGGC CTTGATGAAG AAGCAGAACA GAAACTTTTT 
TCAGAGAAAC GTGTGAAATT GCTTAAGGAA CTTTCCAGGA AGCCAGATAT TTATGAGCGG 
CTTGCTTCAG CCTTGGCTCC CAGCATTTAT GAACATGAAG ATATAAAAAA GGGAATCCTA 
CTTCAACTCT TTGGTGGAAC AAGGAAGGAT TTCAGTCACA CTGGAAGGGG TAAATTCCGT 
GCTGAGATTA ACATCCTTCT GTGTGGTGAC CCTGGCACCA GCAAGTCCCA GCTGCTACAG 
TATGTATACA ACCTGGTTCC CAGAGGCCAG TACACATCTG GAAAAGGCTC CAGTGCAGTT 
GGCCTCACAG CCTATGTGAT GAAAGACCCT GAGACCAGGC AGCTTGTCCT CCAGACAGGT 
GCCCTTGTAC TGAGTGACAA TGGCATATGT TGCATTGATG AGTTTGACAA AATGAATGAA 
AGCACAAGGT CCGTGCTGCA TGAGGTCATG GAACAGCAGA CTCTGTCCAT TGCAAAGGCT 
GGGATCATCT GTCAGCTCAA TGCACGAACC TCTGTCCTGG CAGCAGCAAA CCCTATTGAG 
TCCCAGTGGA ACCCTAAAAA AACAACCATT GAAAATATCC AACTACCACA CACACTGTTG 
TCAAGGTTTG ATCTCATTTT CCTCATGCTA GACCCTCAAG ATGAGGCATA TGACCGACGC 
CTAGCCCACC ACCTGGTTTC ATTGTACTAC CAAAGTGAGG AGCAGGTGGA GCAGGAGTTC 
CTGGACATGG CAGTGCTGAA AGACTACATT GCCTATGCAC ATAGTACTAT CATGCCCCGG 
CTGAGTGAGG AGGCCAGCCA GGCTCTCATT GAGGCTTATG TAAACATGAG GAAGATCGGG 
AGTAGTCGGG GGATGGTTTC TGCTTACCCT CGACAGCTAG AGTCATTAAT TCGCTTAGCA 
GAAGCCCATG CTAAAGTAAG ATTTTCAGAC AAAGTTGAAG CAATCGATGT GGAAGAGGCA 
AAACGCCTTC ACCGGGAGGC TCTGAAGCAG TCTGCCACTG ACCCTCGCAC TGGCATTGTG 
GACATATCTA TTCTTACTAC AGGAATGAGT GCCACTTCTC GTAAACGGAA AGAAGAATTA 
GCTGAAGCAC TGAGAAAACT TATTTTATCT AAGGGTAAAA CACCAGCCTT AAAGTACCAA 
CAGCTATTTG AGGATATTCG GGGACAATCT GACACAGCAA TTACCAAGGA CATGTTTGAA 
GAGGCCCTGC GTGCTTTGGC TGATGATGAT TTCCTAACAG TGACTGGGAA GACTGTCCGC 
CTACTCTGA