Gjb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gjb1
Entrez Gene ID	29584
Full Name	gap junction protein, beta 1
Synonyms	Cx32
General protein information	Preferred Names gap junction protein, beta 1 Names gap junction beta-1 protein GAP junction 28 kDa liver protein connexin-32 gap junction membrane channel protein beta 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22
Summary	component of gap junctions, which connect the cytoplasm of adjacent cells; involved in intercellular transport of small hydrophilic molecules; facilitates cell-cell communication [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601945.1	XP_017457434.1	gap junction beta-1 protein isoform X1
XM_008773255.2	XP_008771477.1	gap junction beta-1 protein isoform X1
NM_017251.2	NP_058947.1	gap junction beta-1 protein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GJB1	XP_538073.1
Xenopus tropicalis (tropical clawed frog)	gjb1	NP_001001240.1
Homo sapiens (human)	GJB1	NP_000157.1
Rattus norvegicus (Norway rat)	Gjb1	NP_058947.1
Pan troglodytes (chimpanzee)	GJB1	XP_521117.1
Bos taurus (cattle)	GJB1	NP_776494.1
Gallus gallus (chicken)	GJB1	NP_989702.1
	GJB1	XP_001101168.1
Mus musculus (house mouse)	Gjb1	NP_032150.2
Danio rerio (zebrafish)	cx31.7	XP_001921623.4

Gene Ontology
Bibliography

Related articles in PubMed

Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes.
Pei H, Zhai C, Li H, Yan F, Qin J, Yuan H, Zhang R, Wang S, Zhang W, Chang M, Wang Y, Pei X
Stem cell research & therapy8(1)252(2017 Nov)

Increased Cx32 expression in spinal cord TrkB oligodendrocytes following peripheral axon injury.
Coulibaly AP, Isaacson LG
Neuroscience letters627115-20(2016 Aug)

Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis.
Kato H, Naiki-Ito A, Naiki T, Suzuki S, Yamashita Y, Sato S, Sagawa H, Kato A, Kuno T, Takahashi S
Oncotarget7(2)2009-21(2016 Jan)

Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats.
Sagawa H, Naiki-Ito A, Kato H, Naiki T, Yamashita Y, Suzuki S, Sato S, Shiomi K, Kato A, Kuno T, Matsuo Y, Kimura M, Takeyama H, Takahashi S
Carcinogenesis36(12)1539-49(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

retrograde influences originating from the peripheral injury site elicit dramatic changes in the central nervous system expression of Connexin 32, which in turn may mediate the plasticity of oligodendrocyte lineage cells observed in the spinal cord following peripheral axon injury.
Title: Increased Cx32 expression in spinal cord TrkB oligodendrocytes following peripheral axon injury.

Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis.
Title: Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis.

Cx32 and luteolin have suppressive roles in inflammation, fibrosis and hepatocarcinogenesis during non-alcoholic steatohepatitis progression.
Title: Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats.

Cx 32 and Cx 43 associated with oligodendrocytes and astrocytes had an important role in the first stages of seizures induced by 4-AP, whereas Cx36 localized to neurons could be associated with later stages.
Title: Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus.

Tryptophan was substituted for residues in all four transmembrane domains of connexin32. Tryptophan substitution was poorly tolerated in all domains, with the greatest impact in TM1 and TM4.
Title: Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32.

The following Gjb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gjb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03402	NM_017251.2 Latest version!	Rattus norvegicus gap junction protein, beta 1 (Gjb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa03402	XM_017601945.1 Latest version!	Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa03402	XM_008773255.2 Latest version!	Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gjb1 ( NM_017251.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058947.1 Rattus norvegicus gap junction protein, beta 1 (Gjb1), mRNA.

Price & Availability↑

CloneID	ORa03402
Clone ID Related Accession (Same CDS sequence)	XM_017601945.1 , XM_008773255.2 , NM_017251.2
Accession Version	NM_017251.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	gap junction beta-1 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK476084.1 and BC078868.1. On Nov 23, 2005 this sequence version replaced NM_017251.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ210131.1, FQ218820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058947.1
CDS	86..937
Translation	MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCEAFPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC

Target ORF information:

RefSeq Version	NM_017251.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gap junction protein, beta 1 (Gjb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017251.2

ORF Insert Sequence:

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gjb1 ( XM_017601945.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457434.1 Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03402
Clone ID Related Accession (Same CDS sequence)	XM_017601945.1 , XM_008773255.2 , NM_017251.2
Accession Version	XM_017601945.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	gap junction beta-1 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457434.1
CDS	133..984
Translation	MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCEAFPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC

Target ORF information:

RefSeq Version	XM_017601945.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601945.1

ORF Insert Sequence:

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gjb1 ( XM_008773255.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771477.1 Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa03402
Clone ID Related Accession (Same CDS sequence)	XM_017601945.1 , XM_008773255.2 , NM_017251.2
Accession Version	XM_008773255.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	gap junction beta-1 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773255.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771477.1
CDS	964..1815
Translation	MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCEAFPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC

Target ORF information:

RefSeq Version	XM_008773255.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gap junction protein, beta 1 (Gjb1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773255.2

ORF Insert Sequence:

ATGAACTGGA CAGGTCTATA CACCTTGCTC AGTGGCGTGA ATCGGCATTC TACAGCCATT 
GGCCGAGTAT GGCTGTCCGT CATCTTTATC TTCAGAATCA TGGTGCTGGT GGTGGCTGCA 
GAGAGCGTGT GGGGTGATGA GAAGTCTTCT TTCATCTGTA ACACCCTCCA GCCGGGCTGT 
AACAGCGTCT GCTATGACCA TTTTTTCCCC ATCTCCCATG TGCGCCTGTG GTCCCTGCAA 
CTCATCTTGG TTTCCACCCC AGCTCTCCTC GTGGCAATGC ACGTGGCTCA CCAACAACAC 
ATAGAAAAGA AAATGCTACG GCTTGAGGGG CACGGGGACC CCCTTCACCT GGAAGAGGTA 
AAGAGGCACA AGGTGCACAT CTCAGGGACA CTGTGGTGGA CCTATGTCAT CAGTGTGGTG 
TTCCGGCTGC TGTTTGAGGC TGTCTTCATG TATGTCTTCT ATCTGCTCTA CCCGGGCTAT 
GCCATGGTGC GGCTGGTCAA GTGTGAGGCC TTCCCCTGCC CCAACACGGT GGACTGCTTC 
GTGTCCCGCC CCACTGAGAA AACCGTCTTC ACTGTCTTTA TGCTCGCCGC CTCCGGCATC 
TGCATTATCC TCAACGTGGC GGAGGTGGTG TACCTCATCA TCCGGGCCTG TGCCCGCCGT 
GCTCAGCGCC GCTCCAATCC GCCCTCCCGC AAGGGCTCGG GCTTCGGCCA CCGCCTCTCA 
CCTGAATACA AGCAGAATGA GATCAACAAG CTGCTGAGCG AGCAGGATGG CTCTCTGAAA 
GACATACTGC GCCGCAGTCC TGGCACTGGG GCCGGGCTGG CTGAGAAGAG CGACCGATGC 
TCAGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes.
Stem cell research & therapy8(1)252(2017 Nov)
Pei H,Zhai C,Li H,Yan F,Qin J,Yuan H,Zhang R,Wang S,Zhang W,Chang M,Wang Y,Pei X

Increased Cx32 expression in spinal cord TrkB oligodendrocytes following peripheral axon injury.
Neuroscience letters627115-20(2016 Aug)
Coulibaly AP,Isaacson LG

Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis.
Oncotarget7(2)2009-21(2016 Jan)
Kato H,Naiki-Ito A,Naiki T,Suzuki S,Yamashita Y,Sato S,Sagawa H,Kato A,Kuno T,Takahashi S

Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats.
Carcinogenesis36(12)1539-49(2015 Dec)
Sagawa H,Naiki-Ito A,Kato H,Naiki T,Yamashita Y,Suzuki S,Sato S,Shiomi K,Kato A,Kuno T,Matsuo Y,Kimura M,Takeyama H,Takahashi S

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Gjb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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