Slc30a5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc30a5
Entrez Gene ID	294698
Full Name	solute carrier family 30 member 5
General protein information	Preferred Names solute carrier family 30 member 5 Names zinc transporter 5 solute carrier family 30 (zinc transporter), member 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106404.1	NP_001099874.1	zinc transporter 5

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc30a5	NP_001099874.1
Canis lupus familiaris (dog)	SLC30A5	XP_850350.1
Bos taurus (cattle)	SLC30A5	NP_001179103.1
Gallus gallus (chicken)	SLC30A5	NP_001026590.2
Caenorhabditis elegans (roundworm)	CELE_Y105E8A.3	NP_740931.2
Xenopus tropicalis (tropical clawed frog)	slc30a5	NP_001015911.1
Homo sapiens (human)	SLC30A5	NP_075053.2
Pan troglodytes (chimpanzee)	SLC30A5	XP_001161060.2
	SLC30A5	XP_001090696.1
Danio rerio (zebrafish)	slc30a5	NP_001002322.1
Mus musculus (house mouse)	Slc30a5	NP_075023.2

Gene Ontology
Bibliography

Related articles in PubMed

Alteration of ZnT5-mediated zinc import into the early secretory pathway affects the secretion of growth hormone from rat pituitary cells.
Petkovic V, Miletta MC, Ebl? A, Fl?ck CE, Mullis PE
Hormone research in paediatrics82(4)245-51(2014)

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes.
Falc?n-P?rez JM, Dell'Angelica EC
Experimental cell research313(7)1473-83(2007 Apr)

Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Inoue K, Matsuda K, Itoh M, Kawaguchi H, Tomoike H, Aoyagi T, Nagai R, Hori M, Nakamura Y, Tanaka T
Human molecular genetics11(15)1775-84(2002 Jul)

A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane.
Cragg RA, Christie GR, Phillips SR, Russi RM, K?ry S, Mathers JC, Taylor PM, Ford D
The Journal of biological chemistry277(25)22789-97(2002 Jun)

Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.
Kambe T, Narita H, Yamaguchi-Iwai Y, Hirose J, Amano T, Sugiura N, Sasaki R, Mori K, Iwanaga T, Nagao M
The Journal of biological chemistry277(21)19049-55(2002 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results suggest that ZnT5 might play an important role in regulated growth hormone secretion that is much greater than previously anticipated
Title: Alteration of ZnT5-mediated zinc import into the early secretory pathway affects the secretion of growth hormone from rat pituitary cells.

The following Slc30a5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc30a5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01143	NM_001106404.1 Latest version!	Rattus norvegicus solute carrier family 30 member 5 (Slc30a5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$447.30 $639.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc30a5 ( NM_001106404.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099874.1 Rattus norvegicus solute carrier family 30 member 5 (Slc30a5), mRNA.

Price & Availability↑

CloneID	ORa01143
Clone ID Related Accession (Same CDS sequence)	NM_001106404.1
Accession Version	NM_001106404.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2283bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	zinc transporter 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473955.1. On or before Oct 4, 2007 this sequence version replaced XM_001062806.1, XM_226722.4. ##Evidence-Data-START## Transcript exon combination :: BC107651.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGAGA AGTACGGCGG GGACCCGCGG CCCGGGCCCG GCGGCGGCCT CGGGCCGGTG 
GACGTGCCCA GCGCCCGATT AACAAAATAC ATTGTATTAC TGTGTTTAAC CAAATGTTTG 
AAGGCTGTGG GACTTTTTGA ATCGTATGAT CTCCTAAAAG CTGTTCACAT TGTTCAATTT 
ATTTTTATAT TAAAGCTCGG GACTGCGTTT TTTATGGTTT TGTTTCAAAA ACCGTTTTCT 
TCTGGGAAAA CCGTTACAAA GCATCAGTGG ATCAAAATAT TTAAACATGC AGTTGCTGGA 
TGTATCATAT CACTTTTATG GTTTTTTGGC CTTACTCTCT GTGGACCACT AAGGACTTTG 
CTGCTGTTTG AACACAGTGA CATTGTCGTC ATCTCTCTGC TCAGTGTTTT ATTCACTAGC 
TCTGGAGGAG GACCAGCAAA GACAAGAGGA GCTGCTTTTT TCATTATTGC TGTGATCTGT 
TTATTGCTTT TCGACAATGA TGATCTCATG GCTAAGATGG CCGAACACCC GGAAGGCCAT 
CATGACAGTG CTCTCACTCA CATGCTTTAT ACAGCTATCG CCTTCCTGGG TGTGGCAGAT 
CACAAGGGTG GCGTACTCTT GCTGGTGCTG GCTTTATGTT GTAAAGTTGG TTTTCACACG 
GCCTCCAGAA AGCTCTCTAT AGATGTTGGT GGAGCTAAGC GCCTTCAGGC CTTATCCCAG 
CTTGTTTCTG TGTTTCTCCT ATGCCCATGG GTGATTGTTC TTTCTGTGAC AACTGAGAGT 
AAGATCGAGT CTTGGTTCCC ACTCATCATG CCTTTCACCA CAGTCATCTT CTTTGTCATG 
ATCCTGGATT TCTACATGGA TTCCGTTTGT TCTGTCAAAA TGGAAGCTTC CAAATGTGCC 
CGCTATGGAT CCTTCCCCAT CTTTATTAGT GCTCTGCTCT TTGGAAACTT CTGGACACAT 
CCAATAACAG ACCAACTGCG GGCTATGAAC AGAGCAGCAC ACCAGGAGAG CACAGAGCAT 
GTCCTGTCTG GAGGAGTGGT AGTGAGTGCT GTGTTCTTCA TTCTGTCGGC CAACATCCTC 
TCATCTCCCT CTAAGAGAGG ACAGAAAGGT ACCCTTATTG GATATTCTCC AGAAGGAACA 
CCGCTCTATC ACTTCATGGG TGATGCTTTT CAGCACAGCT CTCAGTCGGT CCCTAGGTTT 
ATTAAGGACT CACTGAAACA GATTCTTGAG GAGAGTGACT CTAGGCAGAT CTTTTACTTC 
TTGTGCTTGA ATCTGCTCTT CACCTTTGTG GAGTTGTTCT ATGGAGTGCT CACCAACAGT 
CTGGGCCTGA TCTCAGACGG ATTCCACATG CTCTTTGACT GCTCCGCCTT GGTCATGGGA 
CTGTTTGCTG CCCTGGTGAG CAGATGGAAA GCCACCCGGA TTTTCTCCTA CGGGTATGGC 
CGAATAGAAA TTCTCTCTGG ATTTATTAAT GGACTTTTCC TGATAGTGAT AGCTTTTTTT 
GTGTTTCTGG AGTCAGTGGC TAGACTGATT GATCCTCCGG AACTTGACAC AAACATGCTG 
ACACCAGTGT CCATTGGAGG GCTGATAGTA AACCTTATTG GAGTCTGTGC CTTTAGTCAC 
GCCCACAGTC ATGGCCATGG GCCTTCTCAA GGACACTGCC ACTCGGATCA CGGCCATTCC 
CACCATGCTC ATGGACACAG CGACCATGGT CACAGCCACG GATTCACAGG TGGAGGCATG 
AATGCGAACA TGAGGGGTGT ATTTCTCCAT GTTTTGGCAG ATACACTGGG CAGCATTGGC 
GTGATTGTGT CCACAGTTCT TATAGAGCAG TTCGGATGGT TTATTGCTGA TCCCCTGTGT 
TCTCTTTTTA TTGCCGTGTT AATATTTCTC AGTGTTATCC CACTGATTAA AGACGCCTGT 
CAAGTTTTAC TTCTGAGACT ACCACCTGAC TATGAAAAAG AACTACATAT TGCTTTAGAA 
AAGGTACAGA AACTCGAAGG ATTAATATCC TACCGAGACC CTCATTTTTG GCGCCATTCT 
GCCAGTATTG TAGCAGGGAC AATTCACATT CAGGTGACAT CTGATGTGCT GGAACAGAGA 
GTTGTGCAGC AGGTTACAGG AATACTTAAA GATGCGGGAG TAAACAACCT AACAATACAG 
GTGGAAAAGG AGGCGTACTT CCAGCACATG TCTGGCCTAA GCACTGGCTT CCACGATGTC 
CTGGCTATGA CTCAGCAGAT GGAATCCATG AAGTACTGCA AAGACGGCAC TTACATCATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099874.1
CDS	150..2432
Translation	MEEKYGGDPRPGPGGGLGPVDVPSARLTKYIVLLCLTKCLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTVTKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSIDVGGAKRLQALSQLVSVFLLCPWVIVLSVTTESKIESWFPLIMPFTTVIFFVMILDFYMDSVCSVKMEASKCARYGSFPIFISALLFGNFWTHPITDQLRAMNRAAHQESTEHVLSGGVVVSAVFFILSANILSSPSKRGQKGTLIGYSPEGTPLYHFMGDAFQHSSQSVPRFIKDSLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALVSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFLESVARLIDPPELDTNMLTPVSIGGLIVNLIGVCAFSHAHSHGHGPSQGHCHSDHGHSHHAHGHSDHGHSHGFTGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAVLIFLSVIPLIKDACQVLLLRLPPDYEKELHIALEKVQKLEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRVVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTQQMESMKYCKDGTYIM

Target ORF information:

RefSeq Version	NM_001106404.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 30 member 5 (Slc30a5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106404.1

ORF Insert Sequence:

ATGGAGGAGA AGTACGGCGG GGACCCGCGG CCCGGGCCCG GCGGCGGCCT CGGGCCGGTG 
GACGTGCCCA GCGCCCGATT AACAAAATAC ATTGTATTAC TGTGTTTAAC CAAATGTTTG 
AAGGCTGTGG GACTTTTTGA ATCGTATGAT CTCCTAAAAG CTGTTCACAT TGTTCAATTT 
ATTTTTATAT TAAAGCTCGG GACTGCGTTT TTTATGGTTT TGTTTCAAAA ACCGTTTTCT 
TCTGGGAAAA CCGTTACAAA GCATCAGTGG ATCAAAATAT TTAAACATGC AGTTGCTGGA 
TGTATCATAT CACTTTTATG GTTTTTTGGC CTTACTCTCT GTGGACCACT AAGGACTTTG 
CTGCTGTTTG AACACAGTGA CATTGTCGTC ATCTCTCTGC TCAGTGTTTT ATTCACTAGC 
TCTGGAGGAG GACCAGCAAA GACAAGAGGA GCTGCTTTTT TCATTATTGC TGTGATCTGT 
TTATTGCTTT TCGACAATGA TGATCTCATG GCTAAGATGG CCGAACACCC GGAAGGCCAT 
CATGACAGTG CTCTCACTCA CATGCTTTAT ACAGCTATCG CCTTCCTGGG TGTGGCAGAT 
CACAAGGGTG GCGTACTCTT GCTGGTGCTG GCTTTATGTT GTAAAGTTGG TTTTCACACG 
GCCTCCAGAA AGCTCTCTAT AGATGTTGGT GGAGCTAAGC GCCTTCAGGC CTTATCCCAG 
CTTGTTTCTG TGTTTCTCCT ATGCCCATGG GTGATTGTTC TTTCTGTGAC AACTGAGAGT 
AAGATCGAGT CTTGGTTCCC ACTCATCATG CCTTTCACCA CAGTCATCTT CTTTGTCATG 
ATCCTGGATT TCTACATGGA TTCCGTTTGT TCTGTCAAAA TGGAAGCTTC CAAATGTGCC 
CGCTATGGAT CCTTCCCCAT CTTTATTAGT GCTCTGCTCT TTGGAAACTT CTGGACACAT 
CCAATAACAG ACCAACTGCG GGCTATGAAC AGAGCAGCAC ACCAGGAGAG CACAGAGCAT 
GTCCTGTCTG GAGGAGTGGT AGTGAGTGCT GTGTTCTTCA TTCTGTCGGC CAACATCCTC 
TCATCTCCCT CTAAGAGAGG ACAGAAAGGT ACCCTTATTG GATATTCTCC AGAAGGAACA 
CCGCTCTATC ACTTCATGGG TGATGCTTTT CAGCACAGCT CTCAGTCGGT CCCTAGGTTT 
ATTAAGGACT CACTGAAACA GATTCTTGAG GAGAGTGACT CTAGGCAGAT CTTTTACTTC 
TTGTGCTTGA ATCTGCTCTT CACCTTTGTG GAGTTGTTCT ATGGAGTGCT CACCAACAGT 
CTGGGCCTGA TCTCAGACGG ATTCCACATG CTCTTTGACT GCTCCGCCTT GGTCATGGGA 
CTGTTTGCTG CCCTGGTGAG CAGATGGAAA GCCACCCGGA TTTTCTCCTA CGGGTATGGC 
CGAATAGAAA TTCTCTCTGG ATTTATTAAT GGACTTTTCC TGATAGTGAT AGCTTTTTTT 
GTGTTTCTGG AGTCAGTGGC TAGACTGATT GATCCTCCGG AACTTGACAC AAACATGCTG 
ACACCAGTGT CCATTGGAGG GCTGATAGTA AACCTTATTG GAGTCTGTGC CTTTAGTCAC 
GCCCACAGTC ATGGCCATGG GCCTTCTCAA GGACACTGCC ACTCGGATCA CGGCCATTCC 
CACCATGCTC ATGGACACAG CGACCATGGT CACAGCCACG GATTCACAGG TGGAGGCATG 
AATGCGAACA TGAGGGGTGT ATTTCTCCAT GTTTTGGCAG ATACACTGGG CAGCATTGGC 
GTGATTGTGT CCACAGTTCT TATAGAGCAG TTCGGATGGT TTATTGCTGA TCCCCTGTGT 
TCTCTTTTTA TTGCCGTGTT AATATTTCTC AGTGTTATCC CACTGATTAA AGACGCCTGT 
CAAGTTTTAC TTCTGAGACT ACCACCTGAC TATGAAAAAG AACTACATAT TGCTTTAGAA 
AAGGTACAGA AACTCGAAGG ATTAATATCC TACCGAGACC CTCATTTTTG GCGCCATTCT 
GCCAGTATTG TAGCAGGGAC AATTCACATT CAGGTGACAT CTGATGTGCT GGAACAGAGA 
GTTGTGCAGC AGGTTACAGG AATACTTAAA GATGCGGGAG TAAACAACCT AACAATACAG 
GTGGAAAAGG AGGCGTACTT CCAGCACATG TCTGGCCTAA GCACTGGCTT CCACGATGTC 
CTGGCTATGA CTCAGCAGAT GGAATCCATG AAGTACTGCA AAGACGGCAC TTACATCATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Alteration of ZnT5-mediated zinc import into the early secretory pathway affects the secretion of growth hormone from rat pituitary cells.
Hormone research in paediatrics82(4)245-51(2014)
Petkovic V,Miletta MC,Ebl? A,Fl?ck CE,Mullis PE

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes.
Experimental cell research313(7)1473-83(2007 Apr)
Falc?n-P?rez JM,Dell'Angelica EC

Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Human molecular genetics11(15)1775-84(2002 Jul)
Inoue K,Matsuda K,Itoh M,Kawaguchi H,Tomoike H,Aoyagi T,Nagai R,Hori M,Nakamura Y,Tanaka T

A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane.
The Journal of biological chemistry277(25)22789-97(2002 Jun)
Cragg RA,Christie GR,Phillips SR,Russi RM,K?ry S,Mathers JC,Taylor PM,Ford D

Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.
The Journal of biological chemistry277(21)19049-55(2002 May)
Kambe T,Narita H,Yamaguchi-Iwai Y,Hirose J,Amano T,Sugiura N,Sasaki R,Mori K,Iwanaga T,Nagao M

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Slc30a5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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