Gcm1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gcm1
Entrez Gene ID	29394
Full Name	glial cells missing homolog 1
Synonyms	Gcma
General protein information	Preferred Names glial cells missing homolog 1 Names chorion-specific transcription factor GCMa GCM motif protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q31
Summary	transcription factor which differentiates between glial and neuronal tissues [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017186.2	NP_058882.1	chorion-specific transcription factor GCMa

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Gcm1	NP_058882.1
Xenopus tropicalis (tropical clawed frog)	gcm1	NP_001016915.1
	GCM1	XP_001108558.1
Canis lupus familiaris (dog)	GCM1	XP_005627536.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007782	XP_555753.3
Mus musculus (house mouse)	Gcm1	NP_032129.2
Homo sapiens (human)	GCM1	NP_003634.2
Pan troglodytes (chimpanzee)	GCM1	XP_527415.2
Gallus gallus (chicken)	GCM1	NP_996863.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion.
Chang CW, Cheong ML, Chang GD, Tsai MS, Chen H
Molecular human reproduction19(11)745-55(2013 Nov)

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.
Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang H, Wang Y, van Es JH, Clevers H, Leone G, Cross JC, Wang H
PLoS biology11(4)e1001536(2013)

p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth.
Kashif M, Hellwig A, Kolleker A, Shahzad K, Wang H, Lang S, Wolter J, Thati M, Vinnikov I, Bierhaus A, Nawroth PP, Isermann B
Development (Cambridge, England)138(11)2235-47(2011 Jun)

Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast.
Baczyk D, Drewlo S, Proctor L, Dunk C, Lye S, Kingdom J
Cell death and differentiation16(5)719-27(2009 May)

Interaction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2.
Schubert SW, Kardash E, Khan MA, Cheusova T, Kilian K, Wegner M, Hashemolhosseini S
The Journal of biological chemistry279(48)50358-65(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gcm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gcm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03167	NM_017186.2 Latest version!	Rattus norvegicus glial cells missing transcription factor 1 (Gcm1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gcm1 ( NM_017186.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058882.1 Rattus norvegicus glial cells missing transcription factor 1 (Gcm1), mRNA.

Price & Availability↑

CloneID	ORa03167
Clone ID Related Accession (Same CDS sequence)	NM_017186.2
Accession Version	NM_017186.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1311bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	chorion-specific transcription factor GCMa
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF081557.1. On Aug 30, 2012 this sequence version replaced NM_017186.1. ##Evidence-Data-START## Transcript exon combination :: AF081557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMN02642762 [ECO:0000348] ##Evidence-Data-END##

ATGGAACTGG ACGACTTTGA TCCTGAAGAC AAAGAGATAC TGAGCTGGGA TATTAACGAC 
ATGAAGCTGC CTCAGAATGT GAAGAAGACT GACTGGTTCC AGGAGTGGCC AGACTCCTAC 
GTGAAACACA TCTACAGCTC AGACGACAGG AGCGCACAGC GCCATCTGAG CAGCTGGGCC 
ATGCGCAACA CCAACAACCA CAACTCCCGG ATCCTCAAGA AGTCGTGCCT GGGGGTAGTG 
GTGTGCAGCA GGGACTGTTC CACGGAGGAA GGCCGCAAGA TTTACCTGAG ACCCGCCATC 
TGTGACAAAG CCAGGCAGAA GCAGCAGAGG AAAAGCTGTC CCAACTGCAA TGGACCCCTG 
AAACTAATTC CCTGCAGAGG CCACGGCGGC TTCCCGGTCA CCAACTTCTG GAGGCATGAC 
GGACGCTTCA TCTTTTTCCA GTCCAAAGGA GAGCACGATC ATCCCAGGCC GGAGACCAAG 
CTAGAAGCAG AGGCAAGAAG AGCCATGAAG AAAGTGCACA TGGCCTCTGC CTCCAGCTCC 
TTACGGATGA AGGGGAGACC AGAAATGAAG GGTCTCCCAG GTGAAATCCC GAGTCAGGGA 
AGTTTACCTT TAACTTGGTC ATTCCAGGAA GGGGTCCAAC TGCCCAGCGG TTACAGCACA 
CCTTTAATAG CTAACGCTCC CCAGCAGAAC TCCCTCAATG ATTGCCTGTC CTTCCCCAAG 
AGCTATGACT TGGGGGGAAC CACTGAGCTA GAAGATCCAA CTTCCACCTT AGATCCCACG 
AAGCTCTATG AGAGATATAA GTTCTCCAGC AGTAAGGTCT ACAGCGCTGA AGACCAGTTC 
CAGCCTCCTG TCCCCGGGGT GTACGGAGAT TATGATGAAG CACAAACCTG GAATAAAAAT 
GCTGTCTTAG GGAGAAGTCC TACTGACGAC ACCTACTATC CACCCTATCC TCTGCCTGTG 
GCCAGCTGGC CCTGTGACTA CCTTCCCTCC CAGAGCTCTT TGGAGCACTC TCCCCAACAG 
GTTCCACTAG AGCCACCTGC AGCTCAACCC GGCCATCATC CCTTGTGGAC CAATCCCGGA 
GGTGAGCCTT ACGAAGAGAA AGTTCCTGTG GATTTCAGCA GCTATGTGCC TTCTGTCACG 
TACCACTCCC CTCAGCAGGA CCCCTTTCTG CTCGCTTACG GCTCTCATCC TCAGCAGCAG 
TACGCGCTGC CTGGTAAGAG CAACAGGTGG GATTTCGATG AAGAGATGGC GTGCATGGGC 
TTGGATCACT TCAACAACGA GATGCTCCTA AACCTCTGTT CTTTAAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058882.1
CDS	159..1469
Translation	MELDDFDPEDKEILSWDINDMKLPQNVKKTDWFQEWPDSYVKHIYSSDDRSAQRHLSSWAMRNTNNHNSRILKKSCLGVVVCSRDCSTEEGRKIYLRPAICDKARQKQQRKSCPNCNGPLKLIPCRGHGGFPVTNFWRHDGRFIFFQSKGEHDHPRPETKLEAEARRAMKKVHMASASSSLRMKGRPEMKGLPGEIPSQGSLPLTWSFQEGVQLPSGYSTPLIANAPQQNSLNDCLSFPKSYDLGGTTELEDPTSTLDPTKLYERYKFSSSKVYSAEDQFQPPVPGVYGDYDEAQTWNKNAVLGRSPTDDTYYPPYPLPVASWPCDYLPSQSSLEHSPQQVPLEPPAAQPGHHPLWTNPGGEPYEEKVPVDFSSYVPSVTYHSPQQDPFLLAYGSHPQQQYALPGKSNRWDFDEEMACMGLDHFNNEMLLNLCSLK

Target ORF information:

RefSeq Version	NM_017186.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glial cells missing transcription factor 1 (Gcm1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017186.2

ORF Insert Sequence:

ATGGAACTGG ACGACTTTGA TCCTGAAGAC AAAGAGATAC TGAGCTGGGA TATTAACGAC 
ATGAAGCTGC CTCAGAATGT GAAGAAGACT GACTGGTTCC AGGAGTGGCC AGACTCCTAC 
GTGAAACACA TCTACAGCTC AGACGACAGG AGCGCACAGC GCCATCTGAG CAGCTGGGCC 
ATGCGCAACA CCAACAACCA CAACTCCCGG ATCCTCAAGA AGTCGTGCCT GGGGGTAGTG 
GTGTGCAGCA GGGACTGTTC CACGGAGGAA GGCCGCAAGA TTTACCTGAG ACCCGCCATC 
TGTGACAAAG CCAGGCAGAA GCAGCAGAGG AAAAGCTGTC CCAACTGCAA TGGACCCCTG 
AAACTAATTC CCTGCAGAGG CCACGGCGGC TTCCCGGTCA CCAACTTCTG GAGGCATGAC 
GGACGCTTCA TCTTTTTCCA GTCCAAAGGA GAGCACGATC ATCCCAGGCC GGAGACCAAG 
CTAGAAGCAG AGGCAAGAAG AGCCATGAAG AAAGTGCACA TGGCCTCTGC CTCCAGCTCC 
TTACGGATGA AGGGGAGACC AGAAATGAAG GGTCTCCCAG GTGAAATCCC GAGTCAGGGA 
AGTTTACCTT TAACTTGGTC ATTCCAGGAA GGGGTCCAAC TGCCCAGCGG TTACAGCACA 
CCTTTAATAG CTAACGCTCC CCAGCAGAAC TCCCTCAATG ATTGCCTGTC CTTCCCCAAG 
AGCTATGACT TGGGGGGAAC CACTGAGCTA GAAGATCCAA CTTCCACCTT AGATCCCACG 
AAGCTCTATG AGAGATATAA GTTCTCCAGC AGTAAGGTCT ACAGCGCTGA AGACCAGTTC 
CAGCCTCCTG TCCCCGGGGT GTACGGAGAT TATGATGAAG CACAAACCTG GAATAAAAAT 
GCTGTCTTAG GGAGAAGTCC TACTGACGAC ACCTACTATC CACCCTATCC TCTGCCTGTG 
GCCAGCTGGC CCTGTGACTA CCTTCCCTCC CAGAGCTCTT TGGAGCACTC TCCCCAACAG 
GTTCCACTAG AGCCACCTGC AGCTCAACCC GGCCATCATC CCTTGTGGAC CAATCCCGGA 
GGTGAGCCTT ACGAAGAGAA AGTTCCTGTG GATTTCAGCA GCTATGTGCC TTCTGTCACG 
TACCACTCCC CTCAGCAGGA CCCCTTTCTG CTCGCTTACG GCTCTCATCC TCAGCAGCAG 
TACGCGCTGC CTGGTAAGAG CAACAGGTGG GATTTCGATG AAGAGATGGC GTGCATGGGC 
TTGGATCACT TCAACAACGA GATGCTCCTA AACCTCTGTT CTTTAAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion.
Molecular human reproduction19(11)745-55(2013 Nov)
Chang CW,Cheong ML,Chang GD,Tsai MS,Chen H

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.
PLoS biology11(4)e1001536(2013)
Lu J,Zhang S,Nakano H,Simmons DG,Wang S,Kong S,Wang Q,Shen L,Tu Z,Wang W,Wang B,Wang H,Wang Y,van Es JH,Clevers H,Leone G,Cross JC,Wang H

p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth.
Development (Cambridge, England)138(11)2235-47(2011 Jun)
Kashif M,Hellwig A,Kolleker A,Shahzad K,Wang H,Lang S,Wolter J,Thati M,Vinnikov I,Bierhaus A,Nawroth PP,Isermann B

Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast.
Cell death and differentiation16(5)719-27(2009 May)
Baczyk D,Drewlo S,Proctor L,Dunk C,Lye S,Kingdom J

Interaction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2.
The Journal of biological chemistry279(48)50358-65(2004 Nov)
Schubert SW,Kardash E,Khan MA,Cheusova T,Kilian K,Wegner M,Hashemolhosseini S

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Gcm1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報