The following Loxhd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Loxhd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa44947 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001106132.3 | |
| Accession Version | NM_001106132.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 6651bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-02 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | lipoxygenase homology domain-containing protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC139391.3, AABR07072614.1, AABR07032610.1, AABR07032611.1, AABR07032614.1 and AABR07032617.1. On Oct 9, 2014 this sequence version replaced NM_001106132.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN02642618, SAMN04563757 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGATGCCCC AGAAGAAGAA GCGGCGGAAG AAAGACATCG ACTTCCTGGG CTTGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001099602.3 |
| CDS | 1..6651 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001106132.3 |
1 | ATGATGCCCC AGAAGAAGAA GCGGCGGAAG AAAGACATCG ACTTCCTGGG CTTGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa59223 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600876.1 | |
| Accession Version | XM_017600876.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 6837bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | lipoxygenase homology domain-containing protein 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGATGCCCC AGAAGAAGAA GCGGCGGAAG AAAGACATCG ACTTCCTGGG CTTGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017456365.1 |
| CDS | 543..7379 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017600876.1 |
1 | ATGATGCCCC AGAAGAAGAA GCGGCGGAAG AAAGACATCG ACTTCCTGGG CTTGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy. |
Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans. |
A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. |
