Fxr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fxr2
Entrez Gene ID	287433
Full Name	FMR1 autosomal homolog 2
Synonyms	Fxr2h
General protein information	Preferred Names FMR1 autosomal homolog 2 Names fragile X mental retardation syndrome-related protein 2 fragile X mental retardation gene 2, autosomal homolog fragile X mental retardation, autosomal homolog 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100647.1	NP_001094117.1	fragile X mental retardation syndrome-related protein 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FXR2	XP_001171317.2
	FXR2	XP_001118084.2
Bos taurus (cattle)	FXR2	NP_001193218.1
Danio rerio (zebrafish)	fxr2	NP_956505.2
Canis lupus familiaris (dog)	FXR2	XP_546596.3
Mus musculus (house mouse)	Fxr2	NP_035944.2
Rattus norvegicus (Norway rat)	Fxr2	NP_001094117.1
Homo sapiens (human)	FXR2	NP_004851.2

Gene Ontology
Bibliography

Related articles in PubMed

Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in
Wang GX, Smith SJ, Mourrain P
eLife5(2016 10)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

On the aggregation properties of FMRP--a link with the FXTAS syndrome?
Sjeklo?a L, Pauwels K, Pastore A
The FEBS journal278(11)1912-21(2011 Jun)

Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
Cook D, Sanchez-Carbente Mdel R, Lachance C, Radzioch D, Tremblay S, Khandjian EW, DesGroseillers L, Murai KK
PloS one6(10)e26120(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fxr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fxr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04308	NM_001100647.1 Latest version!	Rattus norvegicus FMR1 autosomal homolog 2 (Fxr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fxr2 ( NM_001100647.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094117.1 Rattus norvegicus FMR1 autosomal homolog 2 (Fxr2), mRNA.

Price & Availability↑

CloneID	ORa04308
Clone ID Related Accession (Same CDS sequence)	NM_001100647.1
Accession Version	NM_001100647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2028bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	fragile X mental retardation syndrome-related protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC160929.1. On or before Jun 8, 2008 this sequence version replaced XM_001079469.1, XM_213335.4. ##Evidence-Data-START## Transcript exon combination :: BC160929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGCGGCC TGGCCTCTGG GGGGGATGTG GAGCCGGGAC TGCCCGTCGA GGTGCGGGGC 
TCCAACGGGG CCTTCTACAA GGGCTTTGTT AAGGATGTCC ATGAAGACTC TGTCACTATC 
TTCTTTGAAA ACAACTGGCA GAGTGAGAGA CAGATTCCCT TTGGGGATGT CCGACTACCA 
CCTCCAGCTG ACTACAATAA GGAGATCACA GAAGGAGATG AAGTAGAGGT CTATTCGAGA 
GCCAATGAAC AGGAACCTTG TGGTTGGTGG CTGGCCCGGG TGCGGATGAT GAAGGGAGAT 
TTCTATGTCA TTGAGTATGC TGCCTGTGAT GCTACCTACA ATGAGATTGT CACTCTGGAG 
CGACTTCGGC CAGTCAATCC CAATCCCCTT GCAACCAAAG GCAGCTTCTT CAAGGTTACC 
ATGGCTGTGC CTGAGGATCT TAGAGAGGCC TGCTCCAATG AAAATGTCCA TAAAGAGTTC 
AAGAAAGCAC TGGGAGCCAA CTGCATCTTC CTCAACATCA CAGACAGTGA GCTCTTCATT 
CTGTCAACCA CAGAAGCCCC TGTGAAGAGG GCATCTTTGC TGGGTGACAT GCATTTCCGA 
AGCCTTCGTA CCAAATTGCT GCTCATGTCC CGCAATGAAG AAGCTACTAA GCACCTAGAG 
ACAAGTAAGC AATTGGCAGC AGCATTCCAA GAGGAGTTTA CAGTTCGAGA GGACCTGATG 
GGTCTGGCAA TTGGGACTCA CGGTGCCAAC ATCCAGCAGG CTCGAAAAGT GCCAGGAGTG 
ACTGCCATTG AGTTGGGTGA AGAGACCTGC ACTTTCCGAA TCTATGGGGA GACGCCAGAG 
GCATGCAGAC AGGCTCGAAG CTACCTTGAA TTTTCTGAGG ACTCTGTACA AGTGCCCAGG 
AACCTGGTTG GCAAAGTGAT TGGAAAGAAC GGGAAAGTGA TTCAGGAGAT CGTGGATAAG 
TCTGGTGTGG TGCGGGTTCG TGTGGAAGGT GATAACGACA AGAAGAACCC CAGGGAGGAG 
GGAATGGTTC CCTTCATATT TGTTGGCACC CGAGAGAATA TCAGCAATGC CCAGGCACTG 
CTAGAGTATC ACCTCTCCTA CCTGCAGGAG GTTGAACAGC TTCGCTTGGA GAGACTGCAA 
ATTGATGAAC AGCTTCGGCA GATTGGGCTA GGCTTTCGCC CTCCTGGGAG TGGACGGGGT 
GGCAGTGGTG GTGGCAGTGA CAAGGCGGGC TATACCACAG ACGAGAGCTC CTCCTCTTCC 
CTGCACACGA CCAGAACCTA TGGGGGCAGC TATGGGGGCC GGGGCCGGGG CCGGAGGACT 
GGTGGTCCTG CCTATGGCCC CAGCTCAGAC CCCTCCACAG CTTCTGAGAC AGAGTCAGAA 
AAGAGAGAGG AATCTAATCG AGCAGGACCT GGTGACAGAG ATCCCCCAAG CCGTGGAGAA 
GAAAGCAGGA GGCGGCCAAT TGGGGGCCGG GGAAGGGGAC CCCCACCTGT TCCCCGGCCT 
ACCTCAAGAT ACAACTCATC ATCTATTAGC TCAGTGCTAA AGGATCCAGA CAGCAACCCT 
TACAGCCTAT TGGACACATC TGAACCAGAG CCTCCAGTTG ATTCAGAACC TGGTGAACCT 
CCTCCAGCAA GTGCCCGTCG TCGCCGTTCC CGCCGCCGTC GTACTGATGA AGACAGGACT 
GTCATGGACG GAGGCCTGGA GTCTGACGGT CCTAACGTGA CAGAGAATGG CCTGGAAGAT 
GAATCAAGAC CCCAGAGACG TAATCGCAGC CGCCGCCGCC GTAATCGTGG TAACCGGACT 
GATGGGTCCA TCAGCGGAGA CCGCCAACCA GTGACTGTGG CTGACTACAT CTCACGGGCA 
GAGTCTCAGA GCCGCCAGCG GCCACCTCTG GAGCGCACAA AACCCTCAGA GGATTCTCTT 
TCAGGACAGA AGGGTGACTC TGTCAGCAGG CTTCCCAAGG GCCCCTCAGA GAATGGGGAG 
CTCTCTGCCC CATTGGAGTT GGGTAGTTTG GTGAATGGGG TTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094117.1
CDS	20..2047
Translation	MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITDSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGGSGGGSDKAGYTTDESSSSSLHTTRTYGGSYGGRGRGRRTGGPAYGPSSDPSTASETESEKREESNRAGPGDRDPPSRGEESRRRPIGGRGRGPPPVPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNVTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQRPPLERTKPSEDSLSGQKGDSVSRLPKGPSENGELSAPLELGSLVNGVS

Target ORF information:

RefSeq Version	NM_001100647.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FMR1 autosomal homolog 2 (Fxr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100647.1

ORF Insert Sequence:

ATGGGCGGCC TGGCCTCTGG GGGGGATGTG GAGCCGGGAC TGCCCGTCGA GGTGCGGGGC 
TCCAACGGGG CCTTCTACAA GGGCTTTGTT AAGGATGTCC ATGAAGACTC TGTCACTATC 
TTCTTTGAAA ACAACTGGCA GAGTGAGAGA CAGATTCCCT TTGGGGATGT CCGACTACCA 
CCTCCAGCTG ACTACAATAA GGAGATCACA GAAGGAGATG AAGTAGAGGT CTATTCGAGA 
GCCAATGAAC AGGAACCTTG TGGTTGGTGG CTGGCCCGGG TGCGGATGAT GAAGGGAGAT 
TTCTATGTCA TTGAGTATGC TGCCTGTGAT GCTACCTACA ATGAGATTGT CACTCTGGAG 
CGACTTCGGC CAGTCAATCC CAATCCCCTT GCAACCAAAG GCAGCTTCTT CAAGGTTACC 
ATGGCTGTGC CTGAGGATCT TAGAGAGGCC TGCTCCAATG AAAATGTCCA TAAAGAGTTC 
AAGAAAGCAC TGGGAGCCAA CTGCATCTTC CTCAACATCA CAGACAGTGA GCTCTTCATT 
CTGTCAACCA CAGAAGCCCC TGTGAAGAGG GCATCTTTGC TGGGTGACAT GCATTTCCGA 
AGCCTTCGTA CCAAATTGCT GCTCATGTCC CGCAATGAAG AAGCTACTAA GCACCTAGAG 
ACAAGTAAGC AATTGGCAGC AGCATTCCAA GAGGAGTTTA CAGTTCGAGA GGACCTGATG 
GGTCTGGCAA TTGGGACTCA CGGTGCCAAC ATCCAGCAGG CTCGAAAAGT GCCAGGAGTG 
ACTGCCATTG AGTTGGGTGA AGAGACCTGC ACTTTCCGAA TCTATGGGGA GACGCCAGAG 
GCATGCAGAC AGGCTCGAAG CTACCTTGAA TTTTCTGAGG ACTCTGTACA AGTGCCCAGG 
AACCTGGTTG GCAAAGTGAT TGGAAAGAAC GGGAAAGTGA TTCAGGAGAT CGTGGATAAG 
TCTGGTGTGG TGCGGGTTCG TGTGGAAGGT GATAACGACA AGAAGAACCC CAGGGAGGAG 
GGAATGGTTC CCTTCATATT TGTTGGCACC CGAGAGAATA TCAGCAATGC CCAGGCACTG 
CTAGAGTATC ACCTCTCCTA CCTGCAGGAG GTTGAACAGC TTCGCTTGGA GAGACTGCAA 
ATTGATGAAC AGCTTCGGCA GATTGGGCTA GGCTTTCGCC CTCCTGGGAG TGGACGGGGT 
GGCAGTGGTG GTGGCAGTGA CAAGGCGGGC TATACCACAG ACGAGAGCTC CTCCTCTTCC 
CTGCACACGA CCAGAACCTA TGGGGGCAGC TATGGGGGCC GGGGCCGGGG CCGGAGGACT 
GGTGGTCCTG CCTATGGCCC CAGCTCAGAC CCCTCCACAG CTTCTGAGAC AGAGTCAGAA 
AAGAGAGAGG AATCTAATCG AGCAGGACCT GGTGACAGAG ATCCCCCAAG CCGTGGAGAA 
GAAAGCAGGA GGCGGCCAAT TGGGGGCCGG GGAAGGGGAC CCCCACCTGT TCCCCGGCCT 
ACCTCAAGAT ACAACTCATC ATCTATTAGC TCAGTGCTAA AGGATCCAGA CAGCAACCCT 
TACAGCCTAT TGGACACATC TGAACCAGAG CCTCCAGTTG ATTCAGAACC TGGTGAACCT 
CCTCCAGCAA GTGCCCGTCG TCGCCGTTCC CGCCGCCGTC GTACTGATGA AGACAGGACT 
GTCATGGACG GAGGCCTGGA GTCTGACGGT CCTAACGTGA CAGAGAATGG CCTGGAAGAT 
GAATCAAGAC CCCAGAGACG TAATCGCAGC CGCCGCCGCC GTAATCGTGG TAACCGGACT 
GATGGGTCCA TCAGCGGAGA CCGCCAACCA GTGACTGTGG CTGACTACAT CTCACGGGCA 
GAGTCTCAGA GCCGCCAGCG GCCACCTCTG GAGCGCACAA AACCCTCAGA GGATTCTCTT 
TCAGGACAGA AGGGTGACTC TGTCAGCAGG CTTCCCAAGG GCCCCTCAGA GAATGGGGAG 
CTCTCTGCCC CATTGGAGTT GGGTAGTTTG GTGAATGGGG TTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in
eLife5(2016 10)
Wang GX,Smith SJ,Mourrain P

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

On the aggregation properties of FMRP--a link with the FXTAS syndrome?
The FEBS journal278(11)1912-21(2011 Jun)
Sjeklo?a L,Pauwels K,Pastore A

Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
PloS one6(10)e26120(2011)
Cook D,Sanchez-Carbente Mdel R,Lachance C,Radzioch D,Tremblay S,Khandjian EW,DesGroseillers L,Murai KK

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Fxr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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