Trap1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trap1
Entrez Gene ID	287069
Full Name	TNF receptor-associated protein 1
General protein information	Preferred Names TNF receptor-associated protein 1 Names heat shock protein 75 kDa, mitochondrial HSP 75 TNFR-associated protein 1 TRAP-1 tumor necrosis factor type 1 receptor-associated protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039001.1	NP_001034090.1	heat shock protein 75 kDa, mitochondrial precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Trap1	NP_080784.1
Gallus gallus (chicken)	TRAP1	NP_001006175.1
Danio rerio (zebrafish)	trap1	NP_001107097.1
Drosophila melanogaster (fruit fly)	Trap1	NP_001260726.1
Caenorhabditis elegans (roundworm)	R151.7	NP_741220.2
Pan troglodytes (chimpanzee)	TRAP1	XP_001167908.1
	TRAP1	XP_001094589.2
Canis lupus familiaris (dog)	TRAP1	XP_005621672.1
Bos taurus (cattle)	TRAP1	NP_001033764.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010691	XP_311405.3
Homo sapiens (human)	TRAP1	NP_057376.2
Rattus norvegicus (Norway rat)	Trap1	NP_001034090.1
Danio rerio (zebrafish)	LOC101884569	XP_005163784.1
Xenopus tropicalis (tropical clawed frog)	trap1	XP_002932506.1

Gene Ontology
Bibliography

Related articles in PubMed

Tumor necrosis factor receptor-associated protein 1 improves hypoxia-impaired energy production in cardiomyocytes through increasing activity of cytochrome c oxidase subunit II.
Xiang F, Ma SY, Zhang DX, Zhang Q, Huang YS
The international journal of biochemistry & cell biology79239-248(2016 10)

Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Matassa DS, Amoroso MR, Agliarulo I, Maddalena F, Sisinni L, Paladino S, Romano S, Romano MF, Sagar V, Loreni F, Landriscina M, Esposito F
Cell death & disease4e851(2013 Oct)

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis.
Yoshida S, Tsutsumi S, Muhlebach G, Sourbier C, Lee MJ, Lee S, Vartholomaiou E, Tatokoro M, Beebe K, Miyajima N, Mohney RP, Chen Y, Hasumi H, Xu W, Fukushima H, Nakamura K, Koga F, Kihara K, Trepel J, Picard D, Neckers L
Proceedings of the National Academy of Sciences of the United States of America110(17)E1604-12(2013 Apr)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

tumor necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxia at least partly via potentiation of energy generation
Title: Tumor necrosis factor receptor-associated protein 1 improves hypoxia-impaired energy production in cardiomyocytes through increasing activity of cytochrome c oxidase subunit II.

The following Trap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12396	NM_001039001.1 Latest version!	Rattus norvegicus TNF receptor-associated protein 1 (Trap1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trap1 ( NM_001039001.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001034090.1 Rattus norvegicus TNF receptor-associated protein 1 (Trap1), mRNA.

Price & Availability↑

CloneID	ORa12396
Clone ID Related Accession (Same CDS sequence)	NM_001039001.1
Accession Version	NM_001039001.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Rattus norvegicus(Norway rat)
Product	heat shock protein 75 kDa, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083909.1. ##Evidence-Data-START## Transcript exon combination :: BC083909.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGCGCGAG AGCTGCGAGC TCTGCTGCTG TGGGGCCGCG GGCTGCAGTC TGCACTGAGG 
GCTCCCGCGC TGGCGGGAGT CCGGCGAGGA AAGCCAGTTC TGCACCTTCA GAAGACCACA 
GTCCACTTTA GGGACCCCAC ACAAAGTCTG GCTTCAGGGA TCTCTGCAGG ACAGTTATAT 
AGCACACAGG CAGCTGAGGA CAAGAAGGAG GAGGCCCTGC ACTCCATAAT CAGCAACACT 
GAGGCTGTGC AAGGTTCTGT CTCCAAACAT GAGTTCCAGG CAGAGACAAA GAAGCTTTTG 
GACATTGTAG CCCGTTCACT GTACTCGGAA AAAGAGGTAT TCATACGAGA GCTCATCTCC 
AACGCCAGCG ATGCCTTGGA GAAACTGCGG CACAAGCGGG TGTGTGAAGG CCAGGTGCTG 
CCAGAAATGG AGATTCACCT TCAGACGGAT GCCGAGAAGG GCACCATCAC CATCCAGGAC 
ACTGGGATTG GGATGACCAA GGAGGAGCTG GTGTCCAACC TTGGCACAAT CGCCAGATCA 
GGGTCAAAGG CTTTCCTGGA AGCACTGCAG CACCAGGCAG AGACCAGCAG CAGGATCATC 
GGCCAGTTTG GAGTGGGCTT CTATTCTGCC TTCATGGTGG CTGACAAAGT TGAAGTCTAT 
TCTCGACCGG CAGCCCCAGA GAGCCCAGGT TACCAGTGGC TTTCAGATGG TTCTGGAGTG 
TTTGAAATTG CTGAAGCTTC AGGAGTTAGA CCTGGGACCA AAATAATCAT CCACCTCAAG 
TCAGACTGCA AAGATTTCGC CAACGAGTCC CGGGTGCAAG ATGTGGTAAC AAAGTACAGT 
AACTTTGTCA GCTTCCCCCT GTACCTTAAC GGAAGGCGGA TTAACACTTT GCAGGCCATC 
TGGATGATGG ACCCAAAGGA CATCAGTGAA TTTCAGCACG AGGAATTCTA CCGTTACATC 
GCACAGGCTT ACGATAAGCC TCGCTTCATT TTGCACTACA AGACGGACGC CCCACTCAAT 
ATCCGCAGCA TCTTCTATGT GCCAGAGATG AAACCATCCA TGTTTGACGT GAGCAGGGAG 
CTGGGCTCCA GTGTGGCACT GTATAGCCGC AAGGTGCTCA TCCAGACCAA GGCTACGGAT 
ATCCTGCCCA AGTGGCTGCG CTTCGTTCGA GGTGTGGTGG ACAGTGAGGA CATCCCCCTG 
AACCTCAGCC GAGAGCTCCT GCAGGAGAGC GCCCTCATCC GGAAACTCCG GGACGTTCTA 
CAACAGAGAT TGATCAAATT CTTCATTGAC CAGAGTAAAA AAGATGCTGA AAAATATGCC 
AAGTTTTTTG AAGATTATGG CTTGTTCATG AGGGAGGGCA TTGTGACCAC CGCTGAGCAA 
GACATCAAGG AGGATATTGC AAAGCTGCTA CGGTATGAGT CCTCAGCCCT GCCTGCTGGG 
CAGCTGACCA GCTTATCAGA CTACGCCAGC CGAATGCAGG CTGGCACCCG CAACATCTAT 
TACCTGTGTG CCCCTAACCG TCACCTGGCT GAACATTCAC CCTATTATGA AGCCATGAAG 
CAGAAACAGA CTGAGGTGCT CTTCTGCTAC GAGCAGTTCG ACGAGCTCAC TCTGCTGCAC 
CTGCGGGAGT TTGACAAGAA GAAGCTGATC TCTGTGGAGA CGGACATCGT CGTTGATCAC 
TACAAGGAGG AAAAGTTTGA GGACACATCT CCAGCTGGTG AGCGCCTCTC TGAGAAAGAA 
ACAGAAGAGC TAATGGCATG GATGAGAAAT GCACTGGGGT CCCGTGTCAC CAATGTGAAG 
GTGACTTTCC GCCTGGACAC CCACCCTGCC ATGGTGACCG TGCTAGAGAT GGGGGCTGCT 
CGACATTTCC TGCGCATGCA GCAGCTGGCC AAGACCCAGG AGGAGCGTGC TCAGTTGCTA 
CAGCCCACAC TGGAGATCAA CCCCAGGCAC ACACTAATAA AGAAACTCAA CCAGCTGAGG 
GAGCGTGAGC CGGAGCTAGC CCAGCTGCTA GTGGATCAGA TCTATGAGAA CGCCATGATA 
GCAGCAGGAC TCGTTGATGA TCCCCGGGCC ATGGTAGGCC GCCTGAATGA CCTTCTGGTC 
AAGGCCCTGG AGAGACACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034090.1
CDS	19..2139
Translation	MARELRALLLWGRGLQSALRAPALAGVRRGKPVLHLQKTTVHFRDPTQSLASGISAGQLYSTQAAEDKKEEALHSIISNTEAVQGSVSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKRVCEGQVLPEMEIHLQTDAEKGTITIQDTGIGMTKEELVSNLGTIARSGSKAFLEALQHQAETSSRIIGQFGVGFYSAFMVADKVEVYSRPAAPESPGYQWLSDGSGVFEIAEASGVRPGTKIIIHLKSDCKDFANESRVQDVVTKYSNFVSFPLYLNGRRINTLQAIWMMDPKDISEFQHEEFYRYIAQAYDKPRFILHYKTDAPLNIRSIFYVPEMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFVRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDIAKLLRYESSALPAGQLTSLSDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKQKQTEVLFCYEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDTSPAGERLSEKETEELMAWMRNALGSRVTNVKVTFRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHTLIKKLNQLREREPELAQLLVDQIYENAMIAAGLVDDPRAMVGRLNDLLVKALERH

Target ORF information:

RefSeq Version	NM_001039001.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TNF receptor-associated protein 1 (Trap1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039001.1

ORF Insert Sequence:

ATGGCGCGAG AGCTGCGAGC TCTGCTGCTG TGGGGCCGCG GGCTGCAGTC TGCACTGAGG 
GCTCCCGCGC TGGCGGGAGT CCGGCGAGGA AAGCCAGTTC TGCACCTTCA GAAGACCACA 
GTCCACTTTA GGGACCCCAC ACAAAGTCTG GCTTCAGGGA TCTCTGCAGG ACAGTTATAT 
AGCACACAGG CAGCTGAGGA CAAGAAGGAG GAGGCCCTGC ACTCCATAAT CAGCAACACT 
GAGGCTGTGC AAGGTTCTGT CTCCAAACAT GAGTTCCAGG CAGAGACAAA GAAGCTTTTG 
GACATTGTAG CCCGTTCACT GTACTCGGAA AAAGAGGTAT TCATACGAGA GCTCATCTCC 
AACGCCAGCG ATGCCTTGGA GAAACTGCGG CACAAGCGGG TGTGTGAAGG CCAGGTGCTG 
CCAGAAATGG AGATTCACCT TCAGACGGAT GCCGAGAAGG GCACCATCAC CATCCAGGAC 
ACTGGGATTG GGATGACCAA GGAGGAGCTG GTGTCCAACC TTGGCACAAT CGCCAGATCA 
GGGTCAAAGG CTTTCCTGGA AGCACTGCAG CACCAGGCAG AGACCAGCAG CAGGATCATC 
GGCCAGTTTG GAGTGGGCTT CTATTCTGCC TTCATGGTGG CTGACAAAGT TGAAGTCTAT 
TCTCGACCGG CAGCCCCAGA GAGCCCAGGT TACCAGTGGC TTTCAGATGG TTCTGGAGTG 
TTTGAAATTG CTGAAGCTTC AGGAGTTAGA CCTGGGACCA AAATAATCAT CCACCTCAAG 
TCAGACTGCA AAGATTTCGC CAACGAGTCC CGGGTGCAAG ATGTGGTAAC AAAGTACAGT 
AACTTTGTCA GCTTCCCCCT GTACCTTAAC GGAAGGCGGA TTAACACTTT GCAGGCCATC 
TGGATGATGG ACCCAAAGGA CATCAGTGAA TTTCAGCACG AGGAATTCTA CCGTTACATC 
GCACAGGCTT ACGATAAGCC TCGCTTCATT TTGCACTACA AGACGGACGC CCCACTCAAT 
ATCCGCAGCA TCTTCTATGT GCCAGAGATG AAACCATCCA TGTTTGACGT GAGCAGGGAG 
CTGGGCTCCA GTGTGGCACT GTATAGCCGC AAGGTGCTCA TCCAGACCAA GGCTACGGAT 
ATCCTGCCCA AGTGGCTGCG CTTCGTTCGA GGTGTGGTGG ACAGTGAGGA CATCCCCCTG 
AACCTCAGCC GAGAGCTCCT GCAGGAGAGC GCCCTCATCC GGAAACTCCG GGACGTTCTA 
CAACAGAGAT TGATCAAATT CTTCATTGAC CAGAGTAAAA AAGATGCTGA AAAATATGCC 
AAGTTTTTTG AAGATTATGG CTTGTTCATG AGGGAGGGCA TTGTGACCAC CGCTGAGCAA 
GACATCAAGG AGGATATTGC AAAGCTGCTA CGGTATGAGT CCTCAGCCCT GCCTGCTGGG 
CAGCTGACCA GCTTATCAGA CTACGCCAGC CGAATGCAGG CTGGCACCCG CAACATCTAT 
TACCTGTGTG CCCCTAACCG TCACCTGGCT GAACATTCAC CCTATTATGA AGCCATGAAG 
CAGAAACAGA CTGAGGTGCT CTTCTGCTAC GAGCAGTTCG ACGAGCTCAC TCTGCTGCAC 
CTGCGGGAGT TTGACAAGAA GAAGCTGATC TCTGTGGAGA CGGACATCGT CGTTGATCAC 
TACAAGGAGG AAAAGTTTGA GGACACATCT CCAGCTGGTG AGCGCCTCTC TGAGAAAGAA 
ACAGAAGAGC TAATGGCATG GATGAGAAAT GCACTGGGGT CCCGTGTCAC CAATGTGAAG 
GTGACTTTCC GCCTGGACAC CCACCCTGCC ATGGTGACCG TGCTAGAGAT GGGGGCTGCT 
CGACATTTCC TGCGCATGCA GCAGCTGGCC AAGACCCAGG AGGAGCGTGC TCAGTTGCTA 
CAGCCCACAC TGGAGATCAA CCCCAGGCAC ACACTAATAA AGAAACTCAA CCAGCTGAGG 
GAGCGTGAGC CGGAGCTAGC CCAGCTGCTA GTGGATCAGA TCTATGAGAA CGCCATGATA 
GCAGCAGGAC TCGTTGATGA TCCCCGGGCC ATGGTAGGCC GCCTGAATGA CCTTCTGGTC 
AAGGCCCTGG AGAGACACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor necrosis factor receptor-associated protein 1 improves hypoxia-impaired energy production in cardiomyocytes through increasing activity of cytochrome c oxidase subunit II.
The international journal of biochemistry & cell biology79239-248(2016 10)
Xiang F,Ma SY,Zhang DX,Zhang Q,Huang YS

Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Cell death & disease4e851(2013 Oct)
Matassa DS,Amoroso MR,Agliarulo I,Maddalena F,Sisinni L,Paladino S,Romano S,Romano MF,Sagar V,Loreni F,Landriscina M,Esposito F

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis.
Proceedings of the National Academy of Sciences of the United States of America110(17)E1604-12(2013 Apr)
Yoshida S,Tsutsumi S,Muhlebach G,Sourbier C,Lee MJ,Lee S,Vartholomaiou E,Tatokoro M,Beebe K,Miyajima N,Mohney RP,Chen Y,Hasumi H,Xu W,Fukushima H,Nakamura K,Koga F,Kihara K,Trepel J,Picard D,Neckers L

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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Trap1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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