Slc18a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc18a2
Entrez Gene ID	25549
Full Name	solute carrier family 18 member A2
Synonyms	MNAT,VMAT-2,VMAT2
General protein information	Preferred Names solute carrier family 18 member A2 Names synaptic vesicular amine transporter Solute carrier family 18 A2 (vesicular monoamine transporter 2) VAT2 monoamine transporter solute carrier family 18 (vesicular monoamine transporter), member 2 solute carrier family 18 (vesicular monoamine), member 2 solute carrier family 18 member 2 vesicular amine transporter 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q55
Summary	transports N-methyl-4-phenylpyridinium (MPP+), a neurotoxin metabolite associated with Parkinson's disease [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013031.1	NP_037163.1	synaptic vesicular amine transporter
XM_008760517.2	XP_008758739.1	synaptic vesicular amine transporter isoform X1
XM_017588824.1	XP_017444313.1	synaptic vesicular amine transporter isoform X2
XM_006231664.3	XP_006231726.1	synaptic vesicular amine transporter isoform X2
XM_008760516.2	XP_008758738.1	synaptic vesicular amine transporter isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC18A2	XP_521615.3
Bos taurus (cattle)	SLC18A2	NP_777078.1
Rattus norvegicus (Norway rat)	Slc18a2	NP_037163.1
Gallus gallus (chicken)	SLC18A2	XP_421782.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004476	XP_313775.4
Caenorhabditis elegans (roundworm)	cat-1	NP_001024936.1
Homo sapiens (human)	SLC18A2	NP_003045.2
Mus musculus (house mouse)	Slc18a2	NP_766111.1
	SLC18A2	XP_001095699.2
Canis lupus familiaris (dog)	SLC18A2	XP_544038.2
Danio rerio (zebrafish)	slc18a2	NP_001243154.1
Drosophila melanogaster (fruit fly)	Vmat	NP_001014524.1

Gene Ontology
Bibliography

Related articles in PubMed

Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis.
Yaffe D, Vergara-Jaque A, Forrest LR, Schuldiner S
Proceedings of the National Academy of Sciences of the United States of America113(47)E7390-E7398(2016 Nov)

Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate.
Wang L, Kang Y, Zhang G, Zhang Y, Cui R, Yan W, Tan H, Li S, Wu B, Cui H, Shi G
Experimental gerontology781-11(2016 Jun)

Acrylamide increases dopamine levels by affecting dopamine transport and metabolism related genes in the striatal dopaminergic system.
Pan X, Guo X, Xiong F, Cheng G, Lu Q, Yan H
Toxicology letters236(1)60-8(2015 Jul)

JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.
Choi WS, Kim HW, Xia Z
Toxicology32875-81(2015 Feb)

Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(?)-methylenedioxymethamphetamine.
Lizarraga LE, Cholanians AB, Phan AV, Herndon JM, Lau SS, Monks TJ
Toxicological sciences : an official journal of the Society of Toxicology143(1)209-19(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Up-regulation of VMAT2 expression in aged male rats following chronic testosterone propionate treatment might be involved in the maintenance of dopaminergic function of the nigrostriatal dopaminergic system in aged male rats.
Title: Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate.

Data suggest that expression of Vmat2 and Dat1 (dopamine transporter 1) in dopaminergic neurons in striatum can be down-regulated by dietary factors (here, ingestion of acrylamide, a food contaminant created by heating starchy foods).
Title: Acrylamide increases dopamine levels by affecting dopamine transport and metabolism related genes in the striatal dopaminergic system.

Rotenone induces dopamine neuron death through a series of sequential events including microtubule destabilization, JNK3 activation, VMAT2 inhibition, accumulation of cytosolic dopamine, and generation of ROS.
Title: JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.

Data suggest the involvement of VMAT2 in the thermoregulatory, behavioral, and neurotoxic effects of MDMA.
Title: Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(?)-methylenedioxymethamphetamine.

These results demonstrate asymmetry in noradrenegic genes (Th, NET, and VMAT2) in the right and left stellate ganglia during stress and provide molecular evidence to help explain the difference in response to the stress.
Title: Differential expression of tyrosine hydroxylase and transporters in the right and left stellate ganglion of socially isolated rats.

The following Slc18a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc18a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12704	NM_013031.1 Latest version!	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa24258	XM_017588824.1 Latest version!	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa24258	XM_006231664.3 Latest version!	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43142	XM_008760516.2 Latest version!	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43142	XM_008760517.2 Latest version!	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc18a2 ( NM_013031.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037163.1 Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), mRNA.

Price & Availability↑

CloneID	ORa12704
Clone ID Related Accession (Same CDS sequence)	NM_013031.1
Accession Version	NM_013031.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Rattus norvegicus(Norway rat)
Product	synaptic vesicular amine transporter
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L00603.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L00603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCA 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAGTTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037163.1
CDS	101..1648
Translation	MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEIQTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPSEDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNVQSYPIGDDEESESD

Target ORF information:

RefSeq Version	NM_013031.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013031.1

ORF Insert Sequence:

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCA 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAGTTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc18a2 ( XM_017588824.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444313.1 Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa24258
Clone ID Related Accession (Same CDS sequence)	XM_017588824.1 , XM_006231664.3
Accession Version	XM_017588824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	synaptic vesicular amine transporter isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444313.1
CDS	4245..5792
Translation	MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEIQTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPSEDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNVQSYPIGDDEESESD

Target ORF information:

RefSeq Version	XM_017588824.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588824.1

ORF Insert Sequence:

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc18a2 ( XM_006231664.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231726.1 Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa24258
Clone ID Related Accession (Same CDS sequence)	XM_017588824.1 , XM_006231664.3
Accession Version	XM_006231664.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	synaptic vesicular amine transporter isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231664.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231726.1
CDS	4240..5787
Translation	MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEIQTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPSEDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNVQSYPIGDDEESESD

Target ORF information:

RefSeq Version	XM_006231664.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231664.3

ORF Insert Sequence:

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TCCCTCTGCT 
GGTGGTGCCA TCGCAAAGGC AATTGGCTTT CCTTGGCTTA TGACAATTAT TGGGATAATT 
GATATCGCTT TTGCTCCACT CTGCTTTTTC CTTCGAAGTC CACCTGCTAA GGAGGAAAAA 
ATGGCTATCC TCATGGACCA CAACTGTCCC ATTAAAACAA AGATGTACAC TCAGAATAAT 
GTCCAGTCAT ATCCCATCGG TGATGATGAA GAATCTGAAA GTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc18a2 ( XM_008760517.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758739.1 Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X2, mRNA.

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CloneID	ORa43142
Clone ID Related Accession (Same CDS sequence)	XM_008760517.2 , XM_008760516.2
Accession Version	XM_008760517.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	synaptic vesicular amine transporter isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760517.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TAAGAATGCT 
GGCTTTCAAG AAAACCTTTA CCTTAATGAA GTACAGATAA AACCTCCTAG GAATACAGAA 
TCTTTACATT TTCTGGCGAT AAGATGTTTG GAGAAAGGGC TGATTTTCTG TTTCCCCAAA 
GGTCCCTCTG CTGGTGGTGC CATCGCAAAG GCAATTGGCT TTCCTTGGCT TATGACAATT 
ATTGGGATAA TTGATATCGC TTTTGCTCCA CTCTGCTTTT TCCTTCGAAG TCCACCTGCT 
AAGGAGGAAA AAATGGCTAT CCTCATGGAC CACAACTGTC CCATTAAAAC AAAGATGTAC 
ACTCAGAATA ATGTCCAGTC ATATCCCATC GGTGATGATG AAGAATCTGA AAGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758739.1
CDS	4240..5919
Translation	MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEIQTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPSEDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGKNAGFQENLYLNEVQIKPPRNTESLHFLAIRCLEKGLIFCFPKGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNVQSYPIGDDEESESD

Target ORF information:

RefSeq Version	XM_008760517.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760517.2

ORF Insert Sequence:

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TAAGAATGCT 
GGCTTTCAAG AAAACCTTTA CCTTAATGAA GTACAGATAA AACCTCCTAG GAATACAGAA 
TCTTTACATT TTCTGGCGAT AAGATGTTTG GAGAAAGGGC TGATTTTCTG TTTCCCCAAA 
GGTCCCTCTG CTGGTGGTGC CATCGCAAAG GCAATTGGCT TTCCTTGGCT TATGACAATT 
ATTGGGATAA TTGATATCGC TTTTGCTCCA CTCTGCTTTT TCCTTCGAAG TCCACCTGCT 
AAGGAGGAAA AAATGGCTAT CCTCATGGAC CACAACTGTC CCATTAAAAC AAAGATGTAC 
ACTCAGAATA ATGTCCAGTC ATATCCCATC GGTGATGATG AAGAATCTGA AAGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc18a2 ( XM_008760516.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758738.1 Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43142
Clone ID Related Accession (Same CDS sequence)	XM_008760517.2 , XM_008760516.2
Accession Version	XM_008760516.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	synaptic vesicular amine transporter isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760516.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TAAGAATGCT 
GGCTTTCAAG AAAACCTTTA CCTTAATGAA GTACAGATAA AACCTCCTAG GAATACAGAA 
TCTTTACATT TTCTGGCGAT AAGATGTTTG GAGAAAGGGC TGATTTTCTG TTTCCCCAAA 
GGTCCCTCTG CTGGTGGTGC CATCGCAAAG GCAATTGGCT TTCCTTGGCT TATGACAATT 
ATTGGGATAA TTGATATCGC TTTTGCTCCA CTCTGCTTTT TCCTTCGAAG TCCACCTGCT 
AAGGAGGAAA AAATGGCTAT CCTCATGGAC CACAACTGTC CCATTAAAAC AAAGATGTAC 
ACTCAGAATA ATGTCCAGTC ATATCCCATC GGTGATGATG AAGAATCTGA AAGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758738.1
CDS	4245..5924
Translation	MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEIQTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPSEDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGKNAGFQENLYLNEVQIKPPRNTESLHFLAIRCLEKGLIFCFPKGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNVQSYPIGDDEESESD

Target ORF information:

RefSeq Version	XM_008760516.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 18 member A2 (Slc18a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760516.2

ORF Insert Sequence:

ATGGCCCTGA GCGATCTGGT GCTGCTGCGA TGGCTGCGGG ACAGCCGCCA CTCGCGCAAA 
CTGATCCTGT TCATCGTGTT CCTTGCGCTG CTGCTGGACA ACATGCTGCT CACCGTCGTG 
GTTCCCATCA TCCCCAGCTA TCTGTACAGC ATTAAGCATG AGAAAAACTC TACGGAAATC 
CAGACCACCA GACCAGAGCT CGTGGTCTCC ACCTCCGAAA GCATCTTCTC TTACTATAAC 
AACTCTACTG TGTTGATCAC CGGGAATGCC ACTGGGACTC TTCCAGGAGG GCAGTCACAC 
AAGGCTACCA GCACACAGCA CACTGTGGCT AACACCACTG TCCCTTCGGA CTGTCCCAGT 
GAAGACAGAG ACCTTCTGAA TGAGAATGTG CAAGTTGGGC TGCTGTTTGC CTCCAAAGCC 
ACTGTCCAGC TCCTCACTAA CCCATTCATA GGACTTCTGA CCAACAGAAT TGGCTATCCG 
ATTCCCATGT TTGCCGGCTT CTGCATCATG TTTATCTCAA CAGTTATGTT TGCCTTCTCC 
AGCAGCTATG CCTTCCTGCT GATCGCCAGG TCCCTTCAGG GAATTGGCTC CTCCTGCTCA 
TCCGTGGCTG GGATGGGTAT GCTGGCCAGC GTGTACACAG ATGATGAGGA GAGGGGGAAC 
GCCATGGGCA TTGCTTTGGG TGGCCTGGCC ATGGGAGTCT TAGTGGGACC CCCCTTCGGG 
AGTGTGCTCT ATGAATTTGT GGGGAAGACA GCTCCCTTCC TGGTGCTAGC TGCCTTGGTG 
CTCTTGGATG GGGCTATTCA GCTCTTTGTG CTCCAGCCGT CCCGAGTACA GCCAGAGAGT 
CAGAAGGGGA CACCTCTAAC GACCTTGCTG AAGGATCCAT ACATCCTCAT CGCTGCAGGC 
TCCATCTGCT TTGCAAACAT GGGGATAGCC ATGCTGGAGC CCGCCCTGCC CATCTGGATG 
ATGGAGACCA TGTGTTCCCG AAAGTGGCAG CTGGGCGTTG CTTTCCTCCC GGCGAGCATC 
TCTTATCTCA TTGGAACCAA TATTTTTGGG ATACTTGCAC ACAAAATGGG AAGGTGGCTA 
TGTGCTCTTC TGGGAATGGT AATTGTTGGA ATCAGCATTT TATGCATCCC CTTTGCAAAA 
AATATCTATG GACTCATCGC TCCCAACTTT GGAGTTGGTT TTGCAATTGG GATGGTGGAC 
TCCTCTATGA TGCCTATCAT GGGCTACCTG GTTGACCTGC GGCATGTGTC TGTCTATGGG 
AGTGTTTATG CCATTGCAGA CGTGGCCTTT TGTATGGGCT ATGCTATCGG TAAGAATGCT 
GGCTTTCAAG AAAACCTTTA CCTTAATGAA GTACAGATAA AACCTCCTAG GAATACAGAA 
TCTTTACATT TTCTGGCGAT AAGATGTTTG GAGAAAGGGC TGATTTTCTG TTTCCCCAAA 
GGTCCCTCTG CTGGTGGTGC CATCGCAAAG GCAATTGGCT TTCCTTGGCT TATGACAATT 
ATTGGGATAA TTGATATCGC TTTTGCTCCA CTCTGCTTTT TCCTTCGAAG TCCACCTGCT 
AAGGAGGAAA AAATGGCTAT CCTCATGGAC CACAACTGTC CCATTAAAAC AAAGATGTAC 
ACTCAGAATA ATGTCCAGTC ATATCCCATC GGTGATGATG AAGAATCTGA AAGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America113(47)E7390-E7398(2016 Nov)
Yaffe D,Vergara-Jaque A,Forrest LR,Schuldiner S

Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate.
Experimental gerontology781-11(2016 Jun)
Wang L,Kang Y,Zhang G,Zhang Y,Cui R,Yan W,Tan H,Li S,Wu B,Cui H,Shi G

Acrylamide increases dopamine levels by affecting dopamine transport and metabolism related genes in the striatal dopaminergic system.
Toxicology letters236(1)60-8(2015 Jul)
Pan X,Guo X,Xiong F,Cheng G,Lu Q,Yan H

JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.
Toxicology32875-81(2015 Feb)
Choi WS,Kim HW,Xia Z

Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(?)-methylenedioxymethamphetamine.
Toxicological sciences : an official journal of the Society of Toxicology143(1)209-19(2015 Jan)
Lizarraga LE,Cholanians AB,Phan AV,Herndon JM,Lau SS,Monks TJ

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Slc18a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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