Oaz1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Oaz1
Entrez Gene ID	25502
Full Name	ornithine decarboxylase antizyme 1
Synonyms	ODC-Az,ODCAC,Oaz
General protein information	Preferred Names ornithine decarboxylase antizyme 1 Names ornithine decarboxylase antizyme 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene. [provided by RefSeq, Dec 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001297557.1	NP_001284486.1	ornithine decarboxylase antizyme 1 isoform 2
NM_001301048.1	NP_001287977.1	ornithine decarboxylase antizyme 1 isoform 3
NM_139081.2	NP_620781.1	ornithine decarboxylase antizyme 1 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	OAZ1	NP_001120840.1
	OAZ1	NP_001128372.1
Canis lupus familiaris (dog)	OAZ1	NP_001120706.1
Rattus norvegicus (Norway rat)	Oaz1	NP_620781.1
Bos taurus (cattle)	OAZ1	NP_001120715.1
Homo sapiens (human)	OAZ1	NP_004143.1
Mus musculus (house mouse)	Oaz1	NP_032779.2
Gallus gallus (chicken)	OAZ1	NP_990247.1
Danio rerio (zebrafish)	oaz1a	NP_919240.2
Xenopus tropicalis (tropical clawed frog)	oaz1	NP_988880.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.
Ramos-Molina B, Lambertos A, Lopez-Contreras AJ, Kasprzak JM, Czerwoniec A, Bujnicki JM, Cremades A, Pe?afiel R
FEBS open bio4510-21(2014)

Evidence of a role for antizyme and antizyme inhibitor as regulators of human cancer.
Olsen RR, Zetter BR
Molecular cancer research : MCR9(10)1285-93(2011 Oct)

The influence of corticosterone on antizyme gene expression in early regenerating rat liver.
Ma JM, Yang H, Dong JF, Ning QJ, Li JK
Acta gastro-enterologica Belgica74(2)289-94(2011 Jun)

Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes.
L?pez-Contreras AJ, S?nchez-Laorden BL, Ramos-Molina B, de la Morena ME, Cremades A, Pe?afiel R
Journal of cellular biochemistry107(4)732-40(2009 Jul)

Mitochondrial localization of antizyme is determined by context-dependent alternative utilization of two AUG initiation codons.
Gandre S, Bercovich Z, Kahana C
Mitochondrion2(4)245-56(2003 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Corticosterone treatment induces antizyme 1 protein synthesis in early regenerating rat liver. However, it has little effect on antizyme 1 gene transcription.
Title: The influence of corticosterone on antizyme gene expression in early regenerating rat liver.

overexpression of ornithine decarboxylase antizyme 1 is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.
Title: Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.

NMR study of the solution structure of a stable, folded domain of antizyme isoform-1 consisting of amino acid residues 87-227; it contains eight beta strands & two alpha helices with the strands forming a mixed parallel & antiparallel beta sheet
Title: Solution structure of a conserved domain of antizyme: a protein regulator of polyamines.

The antizyme 1-mediated pathway for cyclin D1 degradation is independent of the previously characterized phosphorylation- and ubiquitination-dependent pathway
Title: Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression.

ability of antizyme 1 to shuttle between the nucleus and the cytoplasm suggests that it has a novel function in the nucleus
Title: Identification of nuclear export signals in antizyme-1.

The following Oaz1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Oaz1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa63248	NM_139081.2 Latest version!	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa63249	NM_001297557.1 Latest version!	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa63250	NM_001301048.1 Latest version!	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Oaz1 ( NM_139081.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620781.1 Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa63248
Clone ID Related Accession (Same CDS sequence)	NM_139081.2
Accession Version	NM_139081.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	ornithine decarboxylase antizyme 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FQ216817.1. On Jul 3, 2014 this sequence version replaced NM_139081.1. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (1, also known as 29 kDa form or AZ-1) is derived from an upstream AUG (at nt 80-82), whereas the shorter isoform (2, also known as 24.5 kDa form or AZ-2) is derived from a downstream AUG (at nt 179-181). This RefSeq represents the longer isoform, which is localized to the mitochondria (PMID:16120325). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ211375.1, FQ213504.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 16120325 ribosomal slippage :: PMID: 7813017 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGAAAT CCTCCCTGCA GCGGATCCTC AACAGCCACT GCTTCGCCAG AGAGAAAGAA 
GGGGACAAAC GCAGCGCCAC GCTTCACGCC AGCCGCACCA TGCCGCTTCT TAGTCAGCAC 
AGCCGCGGCG GCTGCAGCAG CGAGAGTTCT AGGGTTGCCC TTCATTGCTG TAGTAACCTG 
GGTCCGGGGC CTCGGTGGTG CTCCGATGTC CCTCACCCAC CCCTGAAGAT CCCAGGTGGG 
CGAGGGAACA GTCAGCGGGA TCACAGTCTT TCAGCTAGCA TCCTGTACTC CGACGAGCGG 
CTGAATGTGA CAGAGGAGCC GACGTCTAAC GACAAGACCA GGGTCCTGAG CATCCAGTGC 
ACGCTCACGG AGGCCAAGCA GGTCACCTGG AGGGCGGTGT GGAATGGTGG TGGCCTCTAC 
ATCGAGCTCC CAGCTGGGCC TCTGCCAGAA GGCAGCAAGG ACAGTTTTGC AGCTCTACTA 
GAGTTCGCAG AGGAGCAGCT CCGGGCCGAC CACGTTTTCA TCTGCTTCCC CAAGAACCGT 
GAGGACAGAG CCGCCCTACT CCGAACCTTC AGCTTTCTTG GCTTTGAGAT TGTGAGACCC 
GGGCATCCCC TCGTCCCCAA GAGACCCGAC GCTTGCTTCA TGGTCTACAC GCTGGAGAGA 
GAGGACCCGG GTGAGGAGGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620781.1
CDS	join(80..283,285..764)
Translation	MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSESSRVALHCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQCTLTEAKQVTWRAVWNGGGLYIELPAGPLPEGSKDSFAALLEFAEEQLRADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED

Target ORF information:

RefSeq Version	NM_139081.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139081.2

ORF Insert Sequence:

ATGGTGAAAT CCTCCCTGCA GCGGATCCTC AACAGCCACT GCTTCGCCAG AGAGAAAGAA 
GGGGACAAAC GCAGCGCCAC GCTTCACGCC AGCCGCACCA TGCCGCTTCT TAGTCAGCAC 
AGCCGCGGCG GCTGCAGCAG CGAGAGTTCT AGGGTTGCCC TTCATTGCTG TAGTAACCTG 
GGTCCGGGGC CTCGGTGGTG CTCCGATGTC CCTCACCCAC CCCTGAAGAT CCCAGGTGGG 
CGAGGGAACA GTCAGCGGGA TCACAGTCTT TCAGCTAGCA TCCTGTACTC CGACGAGCGG 
CTGAATGTGA CAGAGGAGCC GACGTCTAAC GACAAGACCA GGGTCCTGAG CATCCAGTGC 
ACGCTCACGG AGGCCAAGCA GGTCACCTGG AGGGCGGTGT GGAATGGTGG TGGCCTCTAC 
ATCGAGCTCC CAGCTGGGCC TCTGCCAGAA GGCAGCAAGG ACAGTTTTGC AGCTCTACTA 
GAGTTCGCAG AGGAGCAGCT CCGGGCCGAC CACGTTTTCA TCTGCTTCCC CAAGAACCGT 
GAGGACAGAG CCGCCCTACT CCGAACCTTC AGCTTTCTTG GCTTTGAGAT TGTGAGACCC 
GGGCATCCCC TCGTCCCCAA GAGACCCGAC GCTTGCTTCA TGGTCTACAC GCTGGAGAGA 
GAGGACCCGG GTGAGGAGGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oaz1 ( NM_001297557.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001284486.1 Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa63249
Clone ID Related Accession (Same CDS sequence)	NM_001297557.1
Accession Version	NM_001297557.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	ornithine decarboxylase antizyme 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FQ216817.1. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (1, also known as 29 kDa form or AZ-1) is derived from an upstream AUG (at nt 80-82), whereas the shorter isoform (2, also known as 24.5 kDa form or AZ-2) is derived from a downstream AUG (at nt 179-181). This RefSeq represents the shorter isoform, which is found in the cytosol (PMID:16120325). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ211375.1, FQ213504.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:7813017) gene product(s) localized to mito. :: PMID: 16120325 ribosomal slippage :: PMID: 7813017 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGCTTC TTAGTCAGCA CAGCCGCGGC GGCTGCAGCA GCGAGAGTTC TAGGGTTGCC 
CTTCATTGCT GTAGTAACCT GGGTCCGGGG CCTCGGTGGT GCTCCGATGT CCCTCACCCA 
CCCCTGAAGA TCCCAGGTGG GCGAGGGAAC AGTCAGCGGG ATCACAGTCT TTCAGCTAGC 
ATCCTGTACT CCGACGAGCG GCTGAATGTG ACAGAGGAGC CGACGTCTAA CGACAAGACC 
AGGGTCCTGA GCATCCAGTG CACGCTCACG GAGGCCAAGC AGGTCACCTG GAGGGCGGTG 
TGGAATGGTG GTGGCCTCTA CATCGAGCTC CCAGCTGGGC CTCTGCCAGA AGGCAGCAAG 
GACAGTTTTG CAGCTCTACT AGAGTTCGCA GAGGAGCAGC TCCGGGCCGA CCACGTTTTC 
ATCTGCTTCC CCAAGAACCG TGAGGACAGA GCCGCCCTAC TCCGAACCTT CAGCTTTCTT 
GGCTTTGAGA TTGTGAGACC CGGGCATCCC CTCGTCCCCA AGAGACCCGA CGCTTGCTTC 
ATGGTCTACA CGCTGGAGAG AGAGGACCCG GGTGAGGAGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284486.1
CDS	join(179..283,285..764)
Translation	MPLLSQHSRGGCSSESSRVALHCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQCTLTEAKQVTWRAVWNGGGLYIELPAGPLPEGSKDSFAALLEFAEEQLRADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED

Target ORF information:

RefSeq Version	NM_001297557.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297557.1

ORF Insert Sequence:

ATGCCGCTTC TTAGTCAGCA CAGCCGCGGC GGCTGCAGCA GCGAGAGTTC TAGGGTTGCC 
CTTCATTGCT GTAGTAACCT GGGTCCGGGG CCTCGGTGGT GCTCCGATGT CCCTCACCCA 
CCCCTGAAGA TCCCAGGTGG GCGAGGGAAC AGTCAGCGGG ATCACAGTCT TTCAGCTAGC 
ATCCTGTACT CCGACGAGCG GCTGAATGTG ACAGAGGAGC CGACGTCTAA CGACAAGACC 
AGGGTCCTGA GCATCCAGTG CACGCTCACG GAGGCCAAGC AGGTCACCTG GAGGGCGGTG 
TGGAATGGTG GTGGCCTCTA CATCGAGCTC CCAGCTGGGC CTCTGCCAGA AGGCAGCAAG 
GACAGTTTTG CAGCTCTACT AGAGTTCGCA GAGGAGCAGC TCCGGGCCGA CCACGTTTTC 
ATCTGCTTCC CCAAGAACCG TGAGGACAGA GCCGCCCTAC TCCGAACCTT CAGCTTTCTT 
GGCTTTGAGA TTGTGAGACC CGGGCATCCC CTCGTCCCCA AGAGACCCGA CGCTTGCTTC 
ATGGTCTACA CGCTGGAGAG AGAGGACCCG GGTGAGGAGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oaz1 ( NM_001301048.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001287977.1 Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa63250
Clone ID Related Accession (Same CDS sequence)	NM_001301048.1
Accession Version	NM_001301048.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	ornithine decarboxylase antizyme 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FQ216817.1. Transcript Variant: This variant (2) uses an alternate, in-frame acceptor splice site at the second exon compared to variant 1. The resulting isoform (3) lacks 2 internal amino acids compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EV777141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 16120325 ribosomal slippage :: PMID: 7813017 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGAAAT CCTCCCTGCA GCGGATCCTC AACAGCCACT GCTTCGCCAG AGAGAAAGAA 
GGGGACAAAC GCAGCGCCAC GCTTCACGCC AGCCGCACCA TGCCGCTTCT TAGTCAGCAC 
AGCCGCGGCG GCTGCAGCAG CGAGAGGGTT GCCCTTCATT GCTGTAGTAA CCTGGGTCCG 
GGGCCTCGGT GGTGCTCCGA TGTCCCTCAC CCACCCCTGA AGATCCCAGG TGGGCGAGGG 
AACAGTCAGC GGGATCACAG TCTTTCAGCT AGCATCCTGT ACTCCGACGA GCGGCTGAAT 
GTGACAGAGG AGCCGACGTC TAACGACAAG ACCAGGGTCC TGAGCATCCA GTGCACGCTC 
ACGGAGGCCA AGCAGGTCAC CTGGAGGGCG GTGTGGAATG GTGGTGGCCT CTACATCGAG 
CTCCCAGCTG GGCCTCTGCC AGAAGGCAGC AAGGACAGTT TTGCAGCTCT ACTAGAGTTC 
GCAGAGGAGC AGCTCCGGGC CGACCACGTT TTCATCTGCT TCCCCAAGAA CCGTGAGGAC 
AGAGCCGCCC TACTCCGAAC CTTCAGCTTT CTTGGCTTTG AGATTGTGAG ACCCGGGCAT 
CCCCTCGTCC CCAAGAGACC CGACGCTTGC TTCATGGTCT ACACGCTGGA GAGAGAGGAC 
CCGGGTGAGG AGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287977.1
CDS	join(80..277,279..758)
Translation	MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSERVALHCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQCTLTEAKQVTWRAVWNGGGLYIELPAGPLPEGSKDSFAALLEFAEEQLRADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED

Target ORF information:

RefSeq Version	NM_001301048.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ornithine decarboxylase antizyme 1 (Oaz1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301048.1

ORF Insert Sequence:

ATGGTGAAAT CCTCCCTGCA GCGGATCCTC AACAGCCACT GCTTCGCCAG AGAGAAAGAA 
GGGGACAAAC GCAGCGCCAC GCTTCACGCC AGCCGCACCA TGCCGCTTCT TAGTCAGCAC 
AGCCGCGGCG GCTGCAGCAG CGAGAGGGTT GCCCTTCATT GCTGTAGTAA CCTGGGTCCG 
GGGCCTCGGT GGTGCTCCGA TGTCCCTCAC CCACCCCTGA AGATCCCAGG TGGGCGAGGG 
AACAGTCAGC GGGATCACAG TCTTTCAGCT AGCATCCTGT ACTCCGACGA GCGGCTGAAT 
GTGACAGAGG AGCCGACGTC TAACGACAAG ACCAGGGTCC TGAGCATCCA GTGCACGCTC 
ACGGAGGCCA AGCAGGTCAC CTGGAGGGCG GTGTGGAATG GTGGTGGCCT CTACATCGAG 
CTCCCAGCTG GGCCTCTGCC AGAAGGCAGC AAGGACAGTT TTGCAGCTCT ACTAGAGTTC 
GCAGAGGAGC AGCTCCGGGC CGACCACGTT TTCATCTGCT TCCCCAAGAA CCGTGAGGAC 
AGAGCCGCCC TACTCCGAAC CTTCAGCTTT CTTGGCTTTG AGATTGTGAG ACCCGGGCAT 
CCCCTCGTCC CCAAGAGACC CGACGCTTGC TTCATGGTCT ACACGCTGGA GAGAGAGGAC 
CCGGGTGAGG AGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.
FEBS open bio4510-21(2014)
Ramos-Molina B,Lambertos A,Lopez-Contreras AJ,Kasprzak JM,Czerwoniec A,Bujnicki JM,Cremades A,Pe?afiel R

Evidence of a role for antizyme and antizyme inhibitor as regulators of human cancer.
Molecular cancer research : MCR9(10)1285-93(2011 Oct)
Olsen RR,Zetter BR

The influence of corticosterone on antizyme gene expression in early regenerating rat liver.
Acta gastro-enterologica Belgica74(2)289-94(2011 Jun)
Ma JM,Yang H,Dong JF,Ning QJ,Li JK

Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes.
Journal of cellular biochemistry107(4)732-40(2009 Jul)
L?pez-Contreras AJ,S?nchez-Laorden BL,Ramos-Molina B,de la Morena ME,Cremades A,Pe?afiel R

Mitochondrial localization of antizyme is determined by context-dependent alternative utilization of two AUG initiation codons.
Mitochondrion2(4)245-56(2003 Mar)
Gandre S,Bercovich Z,Kahana C

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Oaz1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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