Cebpe cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cebpe
Entrez Gene ID	25410
Full Name	CCAAT/enhancer binding protein epsilon
Synonyms	C/EPBe,CRP1
General protein information	Preferred Names CCAAT/enhancer binding protein epsilon Names CCAAT/enhancer-binding protein epsilon CCAAT/enhancer binding protein (C/EBP), epsilon CCAAT/enhancer binding protein , epsilon c/EBP epsilon c/EBP-related protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p13
Summary	basic region/leucine zipper transcriptional activator; may mediate cytokine gene expression in mature cells; may play a role in macrophage development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017095.1	NP_058791.1	CCAAT/enhancer-binding protein epsilon

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CEBPE	XP_547729.1
Rattus norvegicus (Norway rat)	Cebpe	NP_058791.1
Xenopus tropicalis (tropical clawed frog)	cebpe	XP_002939064.1
Homo sapiens (human)	CEBPE	NP_001796.2
Bos taurus (cattle)	CEBPE	NP_001179737.1
Pan troglodytes (chimpanzee)	CEBPE	XP_001161080.2
Mus musculus (house mouse)	Cebpe	NP_997014.1
	CEBPE	XP_001106328.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family.
Chumakov AM, Kubota T, Walter S, Koeffler HP
Oncogene23(19)3414-25(2004 Apr)

Macrophage functional maturation and cytokine production are impaired in C/EBP epsilon-deficient mice.
Tavor S, Vuong PT, Park DJ, Gombart AF, Cohen AH, Koeffler HP
Blood99(5)1794-801(2002 Mar)

Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein--epsilon.
Gombart AF, Shiohara M, Kwok SH, Agematsu K, Komiyama A, Koeffler HP
Blood97(9)2561-7(2001 May)

Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon.
Lekstrom-Himes JA, Dorman SE, Kopar P, Holland SM, Gallin JI
The Journal of experimental medicine189(11)1847-52(1999 Jun)

C/EBPepsilon directly interacts with the DNA binding domain of c-myb and cooperatively activates transcription of myeloid promoters.
Verbeek W, Gombart AF, Chumakov AM, M?ller C, Friedman AD, Koeffler HP
Blood93(10)3327-37(1999 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cebpe gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cebpe cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02811	NM_017095.1 Latest version!	Rattus norvegicus CCAAT/enhancer binding protein epsilon (Cebpe), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cebpe ( NM_017095.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058791.1 Rattus norvegicus CCAAT/enhancer binding protein epsilon (Cebpe), mRNA.

Price & Availability↑

CloneID	ORa02811
Clone ID Related Accession (Same CDS sequence)	NM_017095.1
Accession Version	NM_017095.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	CCAAT/enhancer-binding protein epsilon
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF034716.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGTCCCACG GGACCTACTA TGAATGCGAG CCTCGGGGTG GCCAGCAGCC ACTTGAGTTC 
TCAGGGGGTC GAGCTGGGCC CGGGGAGCTG GGGGACATGT GTGAGCATGA GGCCTCCATT 
GACCTCTCCG CCTACATCGA GTCTGGGGAA GAACAGCTAC TTTCTGACCT CTTTGCCATG 
AAGCCAACGC CTGAAGCCCG AAGCCTTAAG GGCCCAGGAA CACCTTCATT TCCTCACTAC 
CTGCCGGCTG ACCCTCGGCC ATTTGCCTAT CCCTCACACA CATTTGGCCC AGATAGGAAG 
GCTTTGGGAC CTGGCATCTA CAGCAACCCA GGGAGCTACG ACCCCAGGGC TGTGGCGGTG 
AAAGAGGAGC CTCGAGGGCC AGAGGGCAAC CGAGGCACCG GCAGAGGCAG CTACAATCCC 
CTGCAGTACC AAGTGGCACA CTGTGGGCAG ACAGCAGTGC ACCTCCCCCC GACCCTGGCA 
GCACCTGGCC AGCCCCTGCG CGTCCTCAAG GCCCCTGTGG CGGCTGCTGC CCCTCCCTGC 
AGCCCCCTTC TCAAGGCACC CTCCCCTGCT GGCCCCTCGC ACAAGGGCAA GAAGGCAGTG 
AACAAAGATA GCCTGGAGTA CCGGCTGCGA CGCGAACGCA ACAACATCGC AGTGCGCAAG 
AGCCGGGACA AGGCCAAGAG GCGCATTATG GAGACACAGC AGAAGGTGTT AGAGTACATG 
GCGGAAAATG AGCGTCTGCG CAGCCGCGTG GACCAGCTCA CCCAGGAGTT AGACACTCTC 
CGCAACCTCT TCCGCCAGAT CCCCGAGGCT GCCAGCCTCA TCAAGGGTGT CGGGGGCTGC 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058791.1
CDS	1..846
Translation	MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAMKPTPEARSLKGPGTPSFPHYLPADPRPFAYPSHTFGPDRKALGPGIYSNPGSYDPRAVAVKEEPRGPEGNRGTGRGSYNPLQYQVAHCGQTAVHLPPTLAAPGQPLRVLKAPVAAAAPPCSPLLKAPSPAGPSHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRIMETQQKVLEYMAENERLRSRVDQLTQELDTLRNLFRQIPEAASLIKGVGGCS

Target ORF information:

RefSeq Version	NM_017095.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CCAAT/enhancer binding protein epsilon (Cebpe), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017095.1

ORF Insert Sequence:

ATGTCCCACG GGACCTACTA TGAATGCGAG CCTCGGGGTG GCCAGCAGCC ACTTGAGTTC 
TCAGGGGGTC GAGCTGGGCC CGGGGAGCTG GGGGACATGT GTGAGCATGA GGCCTCCATT 
GACCTCTCCG CCTACATCGA GTCTGGGGAA GAACAGCTAC TTTCTGACCT CTTTGCCATG 
AAGCCAACGC CTGAAGCCCG AAGCCTTAAG GGCCCAGGAA CACCTTCATT TCCTCACTAC 
CTGCCGGCTG ACCCTCGGCC ATTTGCCTAT CCCTCACACA CATTTGGCCC AGATAGGAAG 
GCTTTGGGAC CTGGCATCTA CAGCAACCCA GGGAGCTACG ACCCCAGGGC TGTGGCGGTG 
AAAGAGGAGC CTCGAGGGCC AGAGGGCAAC CGAGGCACCG GCAGAGGCAG CTACAATCCC 
CTGCAGTACC AAGTGGCACA CTGTGGGCAG ACAGCAGTGC ACCTCCCCCC GACCCTGGCA 
GCACCTGGCC AGCCCCTGCG CGTCCTCAAG GCCCCTGTGG CGGCTGCTGC CCCTCCCTGC 
AGCCCCCTTC TCAAGGCACC CTCCCCTGCT GGCCCCTCGC ACAAGGGCAA GAAGGCAGTG 
AACAAAGATA GCCTGGAGTA CCGGCTGCGA CGCGAACGCA ACAACATCGC AGTGCGCAAG 
AGCCGGGACA AGGCCAAGAG GCGCATTATG GAGACACAGC AGAAGGTGTT AGAGTACATG 
GCGGAAAATG AGCGTCTGCG CAGCCGCGTG GACCAGCTCA CCCAGGAGTT AGACACTCTC 
CGCAACCTCT TCCGCCAGAT CCCCGAGGCT GCCAGCCTCA TCAAGGGTGT CGGGGGCTGC 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family.
Oncogene23(19)3414-25(2004 Apr)
Chumakov AM,Kubota T,Walter S,Koeffler HP

Macrophage functional maturation and cytokine production are impaired in C/EBP epsilon-deficient mice.
Blood99(5)1794-801(2002 Mar)
Tavor S,Vuong PT,Park DJ,Gombart AF,Cohen AH,Koeffler HP

Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein--epsilon.
Blood97(9)2561-7(2001 May)
Gombart AF,Shiohara M,Kwok SH,Agematsu K,Komiyama A,Koeffler HP

Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon.
The Journal of experimental medicine189(11)1847-52(1999 Jun)
Lekstrom-Himes JA,Dorman SE,Kopar P,Holland SM,Gallin JI

C/EBPepsilon directly interacts with the DNA binding domain of c-myb and cooperatively activates transcription of myeloid promoters.
Blood93(10)3327-37(1999 May)
Verbeek W,Gombart AF,Chumakov AM,M?ller C,Friedman AD,Koeffler HP