Egf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Egf
Entrez Gene ID	25313
Full Name	epidermal growth factor
General protein information	Preferred Names epidermal growth factor Names pro-epidermal growth factor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q21
Summary	binds the epidermal growth factor receptor; may play a role in MAP kinase mediated signaling pathways [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012842.1	NP_036974.1	pro-epidermal growth factor precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	EGF	NP_001954.2
Bos taurus (cattle)	EGF	XP_002688149.2
Mus musculus (house mouse)	Egf	NP_034243.2
	EGF	XP_001088957.1
Rattus norvegicus (Norway rat)	Egf	NP_036974.1
Canis lupus familiaris (dog)	EGF	NP_001003094.1
Danio rerio (zebrafish)	egf	NP_991294.1
Pan troglodytes (chimpanzee)	EGF	XP_517395.2
Gallus gallus (chicken)	EGF	NP_001001292.1
Xenopus tropicalis (tropical clawed frog)	egf	NP_001106478.1

Gene Ontology
Bibliography

Related articles in PubMed

CIMAvax-EGF: A New Therapeutic Vaccine for Advanced Non-Small Cell Lung Cancer Patients.
Saavedra D, Crombet T
Frontiers in immunology8269(2017)

A Phase III Clinical Trial of the Epidermal Growth Factor Vaccine CIMAvax-EGF as Switch Maintenance Therapy in Advanced Non-Small Cell Lung Cancer Patients.
Rodriguez PC, Popa X, Mart?nez O, Mendoza S, Santiesteban E, Crespo T, Amador RM, Fleytas R, Acosta SC, Otero Y, Romero GN, de la Torre A, Cala M, Arzuaga L, Vello L, Reyes D, Futiel N, Sabates T, Catala M, Flores YI, Garcia B, Viada C, Lorenzo-Luaces P, Marrero MA, Alonso L, Parra J, Aguilera N, Pomares Y, Sierra P, Rodr?guez G, Mazorra Z, Lage A, Crombet T, Neninger E
Clinical cancer research : an official journal of the American Association for Cancer Research22(15)3782-90(2016 Aug)

Enhanced expression of hepatocyte growth factor in the healing of experimental acute tympanic membrane perforation.
Makuszewska M, Soko?owska M, Hassmann-Pozna?ska E, Bialuk I, Skotnicka B, Bonda T, Resze? J, Winnicka MM
International journal of pediatric otorhinolaryngology79(7)987-92(2015 Jul)

Serum calprotectin, CD26 and EGF to establish a panel for the diagnosis of lung cancer.
Blanco-Prieto S, V?zquez-Iglesias L, Rodr?guez-Girondo M, Barcia-Castro L, Fern?ndez-Villar A, Botana-Rial MI, Rodr?guez-Berrocal FJ, de la Cadena MP
PloS one10(5)e0127318(2015)

Clinical Implication of EGF A61G Polymorphism in the Risk of Non Small Cell Lung Adenocarcinoma Patients: A Case Control Study.
Masroor M, Amit J, Javid J, Mir R, Prasant Y, Imtiyaz A, Mariyam Z, Mohan A, Ray PC, Saxena A
Asian Pacific journal of cancer prevention : APJCP16(17)7529-34(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The expression of EGF was elevated on the first day after tympanic membrane (TM)injury, not reaching statistical significance, and then returned to the level observed in the control TM.
Title: Enhanced expression of hepatocyte growth factor in the healing of experimental acute tympanic membrane perforation.

A decrease in EGF levels may contribute to the formation of visceral hypersensitivity through downregulation of SERT-mediated 5-HT uptake into enterocytes.
Title: Epidermal growth factor upregulates serotonin transporter and its association with visceral hypersensitivity in irritable bowel syndrome.

results indentify EGF signalling as a robust vasculogenic inductive pathway for ATMCs, leading to their transdifferentiation into functional VSMC-like cells.
Title: EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation.

Epidermal growth factor and erythropoietin infusion accelerate functional recovery in combination with rehabilitation.
Title: Epidermal growth factor and erythropoietin infusion accelerate functional recovery in combination with rehabilitation.

The role of EGF on apoptosis, cell proliferation, oxidative stress and antioxidant system in intestinal injury induced by ischemia/reperfusion in rats.
Title: The role of epidermal growth factor in prevention of oxidative injury and apoptosis induced by intestinal ischemia/reperfusion in rats.

The following Egf gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Egf cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42409	NM_012842.1 Latest version!	Rattus norvegicus epidermal growth factor (Egf), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$832.30 $1189.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Egf ( NM_012842.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036974.1 Rattus norvegicus epidermal growth factor (Egf), mRNA.

Price & Availability↑

CloneID	ORa42409
Clone ID Related Accession (Same CDS sequence)	NM_012842.1
Accession Version	NM_012842.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	pro-epidermal growth factor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U04842.1. On Jun 26, 2012 this sequence version replaced XM_003749222.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U04842.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689597, SAMEA2689598 [ECO:0000350] ##Evidence-Data-END##

ATGCTGTTCT CGCTCACCTT CCTGTCGGTG TTTTTAAAGA TTACTGTACT CAGTGTCACA 
GCACAGCAGA CCAGGAACTG TCAGTCAGGT CCTCTCGAGA GAAGCGGGAC TACCACGTAT 
GCCGCCGCCG GTCCTCCCAG GTTCCTGATT TTCTTACAAG GAAACAGCAT CTTTCGGATT 
AACACAGATG GAACAAATCA CCAGCAATTG GTGGTGGATG CCGGCGTCTC AGTGGTCATG 
GATTTTCATT ACAAGGAAGA GAGACTCTAT TGGGTGGATT TAGAAAGACA ACTTTTGCAA 
AGAGTTTTCT TTAATGGGTC AGGACAAGAG ACAGTGTGCA AGGTGGATAA GAATGTGTCT 
GGGCTGGCCA TAAACTGGAT AGATGGGGAG ATTCTCCGGA CGGACCGATG GAAGGGAGTC 
ATCACAGTAA CAGATATGAA CGGGAACAAT TCCCGTGTTC TTCTGAGTTC CTTAAAACGT 
CCTGCAAATA TATTAGTGGA TCCAACAGAG AGGTTGATAT TTTGGTCTTC AGTGGTGACT 
GGCAACCTTC ACAGAGCAGA TCTCGGGGGT ATGGATGTAA AAACACTGCT GGAGGCACCA 
GAGAGGATAT CAGTGCTGAT TCTGGATATC CTGGACAAAA GGCTCTTCTG GGCTCAGGAC 
GGTAGAGAAG GAAGCCACGG TTACATTCAC TCCTGTGACT ATAACGGTGG CTCCATCCAT 
CATATCAGAC ATCAAGCACG GCACGATTTG CTTACTATGG CCATTTTCGG TGACAAGATC 
TTATACTCAG CACTGAAAGA GAAGGCGATT TGGATAGCCG ACAAACACAC TGGGAAGAAT 
GTGGTTCGAG TTAACCTCGA TCCAGCCTCT GTGCCGCCAA GAGAACTGAG AGTCGTGCAC 
CTACATGCAC AGCCCGGGAC AGAGAACCGT GCTCAGGCCT CTGACTCCGA ACGATGCAAA 
CAGAGAAGAG GACAGTGTCT CTACAGTCTC TCTGAGCGAG ACCCCAACTC AGACTCGTCG 
GCATGCGCTG AAGGCTATAC GTTAAGCCGA GACCGGAAGT ACTGCGAAGA TGTCAATGAG 
TGTGCCTTGC AGAATCACGG CTGTACTCTT GGGTGTGAAA ACATCCCTGG ATCCTATTAC 
TGCACATGCC CTACAGGCTT TGTTCTGCTT CCTGATGGGA AACGATGTCA CGAACTTGTT 
GCCTGTCCAG GCAACAGATC AGAGTGTAGC CATGATTGCA TCCTGACATC AGATGGTCCT 
CTGTGCATCT GTCCAGCAGG TTCAGTGCTC GGAAAAGATG GGAAGACATG CACTGGTTGT 
TCCTTCTCCG ATAATGGTGG ATGCAGCCAG ATCTGCCTTC CTCTCAGCCT AGCATCCTGG 
GAATGTGATT GCTTTCCTGG GTACGACCTA CAATTGGACC GAAAGAGCTG TGCAGCTTCC 
ATGGGACCGC AGCCATTTTT ACTGTTTGCA AATTCCCAGG ACATACGACA CATGCATTTT 
GATGGAACAG ACTACAAAAC TCTGCTCAGC CGGCAGATGG GAATGGTTTT TGCCTTGGAT 
TATGACCCCG TGGAAAGCAA GATATATTTT GCACAGACAG CCCTGAAGTG GATAGAGAGG 
GCTAATCTGG ATGGCTCCCA GCGAGAAAGA CGGATCACGG AAGGAGTAGA CACGCCAGAA 
GGTCTTGCCG TGGACTGGAT TGGCCGGAGA ATCTACTGGA CGGACAGTGG GAAGTCTGTC 
ATTGAAGGGA GTGATTTGAG CGGGAAGCAT CATCAAATAA TCATCAAAGA GAGCATCTCA 
AGGCCACGAG GAATAGCTGT GCATCCAAAG GCCAGGAGAC TATTCTGGAC GGACACGGGG 
ATGTCTCCGC GGATTGAAAG CTCTTCCCTT CAAGGTTCTG ACCGGACGCT GATAGCCAGC 
TCTAATCTAC TGGAACCCAG TGGAATCGCG ATTGACTACT TAACAGACAC TTTGTACTGG 
TGTGACACCA AGCTGTCTGT GATTGAAATG GCCGATCTAG ATGGTTCCAA ACGCCGCAGA 
CTTACCCAGA ACGATGTAGG TCACCCATTC TCTCTAGCTG TGTTTGAGGA TCACGTGTGG 
TTCTCGGATT GGGCTATCCC ATCGGTAATA AGGGTGAACA AGAGGACTGG TCAAAACAGG 
GTACGTCTCC GAGGCAGCAT GCTGAAGCCC TCGTCACTGG TTGTGGTCCA CCCATTGGCA 
AAACCAGGTG CAGACCCCTG CTTACACAGG AATGGAGGCT GTGAACACAT CTGCCAAGAG 
AGCCTGGGCA CGGCTCAGTG TCTGTGTCGG GAAGGATTCG TGAAGGCCCC AGATGGGAAA 
ATGTGTCTCA CTCGGAAGGA TGATCAGATA CTGGCCGGTG ACAATGCTGA TCTTAGTAAA 
GAGGTGGCAT CGTTGGACAA CTCCCCTAAG GCTTATGTAC CAGACGATGA TAGGACAGAG 
TCCTCCACAC TAGTGGCTGA GATCATGGTG TCAGGGCTGA ACTATGAAGA TGACTGCGGC 
CCTGGTGGGT GTGGCAGCCA TGCCCACTGT ATTTCAGAGG GAGAGGCAGC TGTGTGTCAG 
TGTTTGAAAG GATTTGCTGG CGATGGAAAC CTGTGTTCTG ATATAGACGA ATGTGAGCTG 
GGTAGCTCAG ACTGTCCTCC CACCTCGTCC AGGTGCATCA ACACCGAAGG TGGCTATGTC 
TGCCAATGCT CAGAAGGCTA CGAGGGAGAT GGGATCTACT GTCTCGACGT TGATGAGTGC 
CAGCAGGGGT CGCACGGCTG CAGCGAGAAT GCCACCTGCA CCAACACGGA GGGAGGCTAC 
AACTGCACCT GTGCAGGCTG CCCATCAGCA CCTGGACTGC CTTGCCCTGA CTCTACCTCA 
CCCTCTCTCC TTGGAAAAGA TGGCTGCCAC TGGGTCCGAA ACAGTAACAC AGGATGCCCG 
CCGTCGTACG ATGGGTACTG CCTCAATGGT GGCGTGTGCA TGTATGTTGA ATCCGTGGAC 
CGCTACGTGT GCAACTGTGT CATTGGCTAT ATTGGAGAAC GATGTCAGCA CCGAGACTTA 
CGTTGGTGGA AGCTGCGCCA TGCTGACTAC GGGCAGAGGC ACGACATCAC TGTGGTGTCT 
GTCTGTGTGG TGGCGCTGGC CCTGCTGCTC CTCTTAGGGA TGTGGGGGAC TTACTACTAC 
AGGACTCGGA AGCAGCTATC AGAGAGCTCA AAGAAGCCTT CCGAAGAGTC AAGCAGCAAC 
GTGAGCAGTA ACGGGCCTGA CAGCAGCGGG GCTGGGGTGT CTTCTGGTCC CCAACCTTGG 
TTTGTGGTCC TAGAGGAACA CCAACAGCCC AAGAATGGGC GTCTGCCTGC CGCTGGCACG 
AACGGCGCAG TAGTAGAGGC TGGCCTGTCT TCCTCCCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036974.1
CDS	389..3790
Translation	MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLGKDGCHWVRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSSGAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL

Target ORF information:

RefSeq Version	NM_012842.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus epidermal growth factor (Egf), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012842.1

ORF Insert Sequence:

ATGCTGTTCT CGCTCACCTT CCTGTCGGTG TTTTTAAAGA TTACTGTACT CAGTGTCACA 
GCACAGCAGA CCAGGAACTG TCAGTCAGGT CCTCTCGAGA GAAGCGGGAC TACCACGTAT 
GCCGCCGCCG GTCCTCCCAG GTTCCTGATT TTCTTACAAG GAAACAGCAT CTTTCGGATT 
AACACAGATG GAACAAATCA CCAGCAATTG GTGGTGGATG CCGGCGTCTC AGTGGTCATG 
GATTTTCATT ACAAGGAAGA GAGACTCTAT TGGGTGGATT TAGAAAGACA ACTTTTGCAA 
AGAGTTTTCT TTAATGGGTC AGGACAAGAG ACAGTGTGCA AGGTGGATAA GAATGTGTCT 
GGGCTGGCCA TAAACTGGAT AGATGGGGAG ATTCTCCGGA CGGACCGATG GAAGGGAGTC 
ATCACAGTAA CAGATATGAA CGGGAACAAT TCCCGTGTTC TTCTGAGTTC CTTAAAACGT 
CCTGCAAATA TATTAGTGGA TCCAACAGAG AGGTTGATAT TTTGGTCTTC AGTGGTGACT 
GGCAACCTTC ACAGAGCAGA TCTCGGGGGT ATGGATGTAA AAACACTGCT GGAGGCACCA 
GAGAGGATAT CAGTGCTGAT TCTGGATATC CTGGACAAAA GGCTCTTCTG GGCTCAGGAC 
GGTAGAGAAG GAAGCCACGG TTACATTCAC TCCTGTGACT ATAACGGTGG CTCCATCCAT 
CATATCAGAC ATCAAGCACG GCACGATTTG CTTACTATGG CCATTTTCGG TGACAAGATC 
TTATACTCAG CACTGAAAGA GAAGGCGATT TGGATAGCCG ACAAACACAC TGGGAAGAAT 
GTGGTTCGAG TTAACCTCGA TCCAGCCTCT GTGCCGCCAA GAGAACTGAG AGTCGTGCAC 
CTACATGCAC AGCCCGGGAC AGAGAACCGT GCTCAGGCCT CTGACTCCGA ACGATGCAAA 
CAGAGAAGAG GACAGTGTCT CTACAGTCTC TCTGAGCGAG ACCCCAACTC AGACTCGTCG 
GCATGCGCTG AAGGCTATAC GTTAAGCCGA GACCGGAAGT ACTGCGAAGA TGTCAATGAG 
TGTGCCTTGC AGAATCACGG CTGTACTCTT GGGTGTGAAA ACATCCCTGG ATCCTATTAC 
TGCACATGCC CTACAGGCTT TGTTCTGCTT CCTGATGGGA AACGATGTCA CGAACTTGTT 
GCCTGTCCAG GCAACAGATC AGAGTGTAGC CATGATTGCA TCCTGACATC AGATGGTCCT 
CTGTGCATCT GTCCAGCAGG TTCAGTGCTC GGAAAAGATG GGAAGACATG CACTGGTTGT 
TCCTTCTCCG ATAATGGTGG ATGCAGCCAG ATCTGCCTTC CTCTCAGCCT AGCATCCTGG 
GAATGTGATT GCTTTCCTGG GTACGACCTA CAATTGGACC GAAAGAGCTG TGCAGCTTCC 
ATGGGACCGC AGCCATTTTT ACTGTTTGCA AATTCCCAGG ACATACGACA CATGCATTTT 
GATGGAACAG ACTACAAAAC TCTGCTCAGC CGGCAGATGG GAATGGTTTT TGCCTTGGAT 
TATGACCCCG TGGAAAGCAA GATATATTTT GCACAGACAG CCCTGAAGTG GATAGAGAGG 
GCTAATCTGG ATGGCTCCCA GCGAGAAAGA CGGATCACGG AAGGAGTAGA CACGCCAGAA 
GGTCTTGCCG TGGACTGGAT TGGCCGGAGA ATCTACTGGA CGGACAGTGG GAAGTCTGTC 
ATTGAAGGGA GTGATTTGAG CGGGAAGCAT CATCAAATAA TCATCAAAGA GAGCATCTCA 
AGGCCACGAG GAATAGCTGT GCATCCAAAG GCCAGGAGAC TATTCTGGAC GGACACGGGG 
ATGTCTCCGC GGATTGAAAG CTCTTCCCTT CAAGGTTCTG ACCGGACGCT GATAGCCAGC 
TCTAATCTAC TGGAACCCAG TGGAATCGCG ATTGACTACT TAACAGACAC TTTGTACTGG 
TGTGACACCA AGCTGTCTGT GATTGAAATG GCCGATCTAG ATGGTTCCAA ACGCCGCAGA 
CTTACCCAGA ACGATGTAGG TCACCCATTC TCTCTAGCTG TGTTTGAGGA TCACGTGTGG 
TTCTCGGATT GGGCTATCCC ATCGGTAATA AGGGTGAACA AGAGGACTGG TCAAAACAGG 
GTACGTCTCC GAGGCAGCAT GCTGAAGCCC TCGTCACTGG TTGTGGTCCA CCCATTGGCA 
AAACCAGGTG CAGACCCCTG CTTACACAGG AATGGAGGCT GTGAACACAT CTGCCAAGAG 
AGCCTGGGCA CGGCTCAGTG TCTGTGTCGG GAAGGATTCG TGAAGGCCCC AGATGGGAAA 
ATGTGTCTCA CTCGGAAGGA TGATCAGATA CTGGCCGGTG ACAATGCTGA TCTTAGTAAA 
GAGGTGGCAT CGTTGGACAA CTCCCCTAAG GCTTATGTAC CAGACGATGA TAGGACAGAG 
TCCTCCACAC TAGTGGCTGA GATCATGGTG TCAGGGCTGA ACTATGAAGA TGACTGCGGC 
CCTGGTGGGT GTGGCAGCCA TGCCCACTGT ATTTCAGAGG GAGAGGCAGC TGTGTGTCAG 
TGTTTGAAAG GATTTGCTGG CGATGGAAAC CTGTGTTCTG ATATAGACGA ATGTGAGCTG 
GGTAGCTCAG ACTGTCCTCC CACCTCGTCC AGGTGCATCA ACACCGAAGG TGGCTATGTC 
TGCCAATGCT CAGAAGGCTA CGAGGGAGAT GGGATCTACT GTCTCGACGT TGATGAGTGC 
CAGCAGGGGT CGCACGGCTG CAGCGAGAAT GCCACCTGCA CCAACACGGA GGGAGGCTAC 
AACTGCACCT GTGCAGGCTG CCCATCAGCA CCTGGACTGC CTTGCCCTGA CTCTACCTCA 
CCCTCTCTCC TTGGAAAAGA TGGCTGCCAC TGGGTCCGAA ACAGTAACAC AGGATGCCCG 
CCGTCGTACG ATGGGTACTG CCTCAATGGT GGCGTGTGCA TGTATGTTGA ATCCGTGGAC 
CGCTACGTGT GCAACTGTGT CATTGGCTAT ATTGGAGAAC GATGTCAGCA CCGAGACTTA 
CGTTGGTGGA AGCTGCGCCA TGCTGACTAC GGGCAGAGGC ACGACATCAC TGTGGTGTCT 
GTCTGTGTGG TGGCGCTGGC CCTGCTGCTC CTCTTAGGGA TGTGGGGGAC TTACTACTAC 
AGGACTCGGA AGCAGCTATC AGAGAGCTCA AAGAAGCCTT CCGAAGAGTC AAGCAGCAAC 
GTGAGCAGTA ACGGGCCTGA CAGCAGCGGG GCTGGGGTGT CTTCTGGTCC CCAACCTTGG 
TTTGTGGTCC TAGAGGAACA CCAACAGCCC AAGAATGGGC GTCTGCCTGC CGCTGGCACG 
AACGGCGCAG TAGTAGAGGC TGGCCTGTCT TCCTCCCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CIMAvax-EGF: A New Therapeutic Vaccine for Advanced Non-Small Cell Lung Cancer Patients.
Frontiers in immunology8269(2017)
Saavedra D,Crombet T

A Phase III Clinical Trial of the Epidermal Growth Factor Vaccine CIMAvax-EGF as Switch Maintenance Therapy in Advanced Non-Small Cell Lung Cancer Patients.
Clinical cancer research : an official journal of the American Association for Cancer Research22(15)3782-90(2016 Aug)
Rodriguez PC,Popa X,Mart?nez O,Mendoza S,Santiesteban E,Crespo T,Amador RM,Fleytas R,Acosta SC,Otero Y,Romero GN,de la Torre A,Cala M,Arzuaga L,Vello L,Reyes D,Futiel N,Sabates T,Catala M,Flores YI,Garcia B,Viada C,Lorenzo-Luaces P,Marrero MA,Alonso L,Parra J,Aguilera N,Pomares Y,Sierra P,Rodr?guez G,Mazorra Z,Lage A,Crombet T,Neninger E

Enhanced expression of hepatocyte growth factor in the healing of experimental acute tympanic membrane perforation.
International journal of pediatric otorhinolaryngology79(7)987-92(2015 Jul)
Makuszewska M,Soko?owska M,Hassmann-Pozna?ska E,Bialuk I,Skotnicka B,Bonda T,Resze? J,Winnicka MM

Serum calprotectin, CD26 and EGF to establish a panel for the diagnosis of lung cancer.
PloS one10(5)e0127318(2015)
Blanco-Prieto S,V?zquez-Iglesias L,Rodr?guez-Girondo M,Barcia-Castro L,Fern?ndez-Villar A,Botana-Rial MI,Rodr?guez-Berrocal FJ,de la Cadena MP

Clinical Implication of EGF A61G Polymorphism in the Risk of Non Small Cell Lung Adenocarcinoma Patients: A Case Control Study.
Asian Pacific journal of cancer prevention : APJCP16(17)7529-34(2015)
Masroor M,Amit J,Javid J,Mir R,Prasant Y,Imtiyaz A,Mariyam Z,Mohan A,Ray PC,Saxena A

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Egf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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