Cox6a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cox6a1
Entrez Gene ID	25282
Full Name	cytochrome c oxidase subunit 6A1
Synonyms	COX6AL
General protein information	Preferred Names cytochrome c oxidase subunit 6A1 Names cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit VIa (liver) cytochrome c oxidase polypeptide VIa-liver cytochrome c oxidase, subunit VIa, polypeptide 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16
Summary	liver isoform of cytochrome-c oxidase subunit VIa [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012814.1	NP_036946.1	cytochrome c oxidase subunit 6A1, mitochondrial precursor

Pathways from BioSystems

Homologies

	LOC696956	XP_002808040.1
Mus musculus (house mouse)	Cox6a1	NP_031774.1
Rattus norvegicus (Norway rat)	Cox6a1	NP_036946.1
Canis lupus familiaris (dog)	LOC477508	XP_534704.3
Gallus gallus (chicken)	COX6A1	NP_001264438.1
Danio rerio (zebrafish)	cox6a1	NP_001005592.1
Xenopus tropicalis (tropical clawed frog)	cox6a1	NP_001016543.1
Homo sapiens (human)	COX6A1	NP_004364.2
Pan troglodytes (chimpanzee)	LOC100616508	XP_003339284.1
Drosophila melanogaster (fruit fly)	levy	NP_611805.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000851	XP_316821.4

Gene Ontology
Bibliography

Related articles in PubMed

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)

Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment.
Lee NH, Weinstock KG, Kirkness EF, Earle-Hughes JA, Fuldner RA, Marmaros S, Glodek A, Gocayne JD, Adams MD, Kerlavage AR
Proceedings of the National Academy of Sciences of the United States of America92(18)8303-7(1995 Aug)

Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.
Sch?gger H, Noack H, Halangk W, Brandt U, von Jagow G
European journal of biochemistry230(1)235-41(1995 May)

Structural organisation of the rat genes encoding liver- and heart-type of cytochrome c oxidase subunit VIa and a pseudogene related to the COXVIa-L cDNA.
Mell OC, Seibel P, Kadenbach B
Gene140(2)179-86(1994 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cox6a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cox6a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12389	NM_012814.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 6A1 (Cox6a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cox6a1 ( NM_012814.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036946.1 Rattus norvegicus cytochrome c oxidase subunit 6A1 (Cox6a1), mRNA.

Price & Availability↑

CloneID	ORa12389
Clone ID Related Accession (Same CDS sequence)	NM_012814.1
Accession Version	NM_012814.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 6A1, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB716915.1, X12553.1 and AA685532.1. On Oct 17, 2005 this sequence version replaced XM_341094.2. ##Evidence-Data-START## Transcript exon combination :: CB716915.1, FQ221968.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGCGTCGG CGGTGCTGAG TGCGTCTCGA GTCTCTGGGC TGCTGGGCCG GGCCCTCCCA 
CGGGTGGGGC GGCCCATGTC GAGTGGCGCC CACGGCGAGG AGGGTTCAGC TCGTATTTGG 
AAGGCCCTCA CCTACTTCGT GGCGCTGCCC GGGGTGGGAG TGAGCATGCT CAACGTTTTC 
CTGAAGTCGC GACACGAAGA GCACGAGAGA CCCGAGTTCG TCGCCTACCC CCATCTCCGC 
ATCAGGACTA AGCCCTTCCC CTGGGGAGAT GGTAACCATA CCCTCTTCCA CAATCCTCAC 
ATGAACCCGC TTCCGACTGG CTATGAAGAT GAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036946.1
CDS	23..358
Translation	MASAVLSASRVSGLLGRALPRVGRPMSSGAHGEEGSARIWKALTYFVALPGVGVSMLNVFLKSRHEEHERPEFVAYPHLRIRTKPFPWGDGNHTLFHNPHMNPLPTGYEDE

Target ORF information:

RefSeq Version	NM_012814.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 6A1 (Cox6a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012814.1

ORF Insert Sequence:

ATGGCGTCGG CGGTGCTGAG TGCGTCTCGA GTCTCTGGGC TGCTGGGCCG GGCCCTCCCA 
CGGGTGGGGC GGCCCATGTC GAGTGGCGCC CACGGCGAGG AGGGTTCAGC TCGTATTTGG 
AAGGCCCTCA CCTACTTCGT GGCGCTGCCC GGGGTGGGAG TGAGCATGCT CAACGTTTTC 
CTGAAGTCGC GACACGAAGA GCACGAGAGA CCCGAGTTCG TCGCCTACCC CCATCTCCGC 
ATCAGGACTA AGCCCTTCCC CTGGGGAGAT GGTAACCATA CCCTCTTCCA CAATCCTCAC 
ATGAACCCGC TTCCGACTGG CTATGAAGAT GAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Cell115(5)629-40(2003 Nov)
Mootha VK,Bunkenborg J,Olsen JV,Hjerrild M,Wisniewski JR,Stahl E,Bolouri MS,Ray HN,Sihag S,Kamal M,Patterson N,Lander ES,Mann M

Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment.
Proceedings of the National Academy of Sciences of the United States of America92(18)8303-7(1995 Aug)
Lee NH,Weinstock KG,Kirkness EF,Earle-Hughes JA,Fuldner RA,Marmaros S,Glodek A,Gocayne JD,Adams MD,Kerlavage AR

Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.
European journal of biochemistry230(1)235-41(1995 May)
Sch?gger H,Noack H,Halangk W,Brandt U,von Jagow G

Structural organisation of the rat genes encoding liver- and heart-type of cytochrome c oxidase subunit VIa and a pseudogene related to the COXVIa-L cDNA.
Gene140(2)179-86(1994 Mar)
Mell OC,Seibel P,Kadenbach B