Cd4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd4
Entrez Gene ID	24932
Full Name	Cd4 molecule
Synonyms	W3/25,p55
General protein information	Preferred Names Cd4 molecule Names T-cell surface glycoprotein CD4 CD4 antigen T-cell surface antigen T4/Leu-3 W3/25 antigen
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42
Summary	MHC class II binding protein that may be a candidate gene for collagen-induced arthritis; human CD4 is a receptor required for HIV infection [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012705.1	NP_036837.1	T-cell surface glycoprotein CD4 precursor
XM_008763280.2	XP_008761502.1	T-cell surface glycoprotein CD4 isoform X1
XM_006237333.3	XP_006237395.1	T-cell surface glycoprotein CD4 isoform X2
XM_006237331.3	XP_006237393.1	T-cell surface glycoprotein CD4 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cd4	NP_036837.1
Bos taurus (cattle)	CD4	NP_001096695.1
Pan troglodytes (chimpanzee)	CD4	NP_001009043.1
	CD4	NP_001036127.1
Canis lupus familiaris (dog)	CD4	NP_001003252.1
Homo sapiens (human)	CD4	NP_000607.1
Mus musculus (house mouse)	Cd4	NP_038516.1
Gallus gallus (chicken)	CD4	NP_989980.1

Gene Ontology
Bibliography

Related articles in PubMed

C4d Deposition Reveals Myocardial Infarction After Cardiac Arrest--Experimental Study.
Vuohelainen V, Paavonen T, Hamalainen M, Moilanen E, Mennander AA
Advances in clinical and experimental medicine : official organ Wroclaw Medical University24(3)393-9(2015 May-Jun)

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.
Zhen A, Krutzik SR, Levin BR, Kasparian S, Zack JA, Kitchen SG
Journal of virology88(17)9934-46(2014 Sep)

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence.
Nowell CS, Bredenkamp N, Tet?lin S, Jin X, Tischner C, Vaidya H, Sheridan JM, Stenhouse FH, Heussen R, Smith AJ, Blackburn CC
PLoS genetics7(11)e1002348(2011 Nov)

Loss of surface antigens is a conserved feature of apoptotic lymphocytes from several mammalian species.
Diaz D, Chara L, Chevarria J, Ubeda M, Mu?oz L, Barcenilla H, S?nchez MA, Moreno Z, Monserrat J, Albillos A, Prieto A, Alvarez-Mon M
Cellular immunology271(1)163-72(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increased C4d deposition may be amenable to identify early myocardial infarction after cardiac arrest.
Title: C4d Deposition Reveals Myocardial Infarction After Cardiac Arrest--Experimental Study.

Data show several homologies across human, rat and mouse in the kinetic of loss of several LAgs such as CD5, CD4 and CD28.
Title: Loss of surface antigens is a conserved feature of apoptotic lymphocytes from several mammalian species.

Capillary C4d deposition is a marker of antibody-mediated rejection in kidney transplantation and can be detected by various staining methods.
Title: Analysis of different staining techniques for c4d detection in renal allograft biopsies.

Clear trend toward worse graft survival in patients with focal C4d after kidney transplantaation.
Title: Focal C4d+ in renal allografts is associated with the presence of donor-specific antibodies and decreased allograft survival.

In this EAE model, perivascular cells, microglia and macrophages showed different dynamics; microglial cells expressed CD4 during the recovery phase, suggesting microglial CD4 expression in the resolution of the immune response.
Title: CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model.

The following Cd4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00691	NM_012705.1 Latest version!	Rattus norvegicus Cd4 molecule (Cd4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa00691	XM_008763280.2 Latest version!	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa00691	XM_006237331.3 Latest version!	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa27751	XM_006237333.3 Latest version!	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd4 ( NM_012705.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036837.1 Rattus norvegicus Cd4 molecule (Cd4), mRNA.

Price & Availability↑

CloneID	ORa00691
Clone ID Related Accession (Same CDS sequence)	NM_012705.1 , XM_008763280.2 , XM_006237331.3
Accession Version	NM_012705.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	T-cell surface glycoprotein CD4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M15768.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M15768.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036837.1
CDS	54..1427
Translation	MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNKLLIKGSLELYSRFDSRKNAWERGSFPLIINKLRMEDSQTYVCELENKKEEVELWVFRVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSKAFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFASTSITAYKSEGESAEFSFPLNLGEESLQGELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDRGILYQEVNLVVMKVTQPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQEKVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLNQTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI

Target ORF information:

RefSeq Version	NM_012705.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd4 molecule (Cd4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012705.1

ORF Insert Sequence:

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd4 ( XM_008763280.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761502.1 Rattus norvegicus Cd4 molecule (Cd4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa00691
Clone ID Related Accession (Same CDS sequence)	NM_012705.1 , XM_008763280.2 , XM_006237331.3
Accession Version	XM_008763280.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-cell surface glycoprotein CD4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763280.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761502.1
CDS	1204..2577
Translation	MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNKLLIKGSLELYSRFDSRKNAWERGSFPLIINKLRMEDSQTYVCELENKKEEVELWVFRVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSKAFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFASTSITAYKSEGESAEFSFPLNLGEESLQGELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDRGILYQEVNLVVMKVTQPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQEKVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLNQTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI

Target ORF information:

RefSeq Version	XM_008763280.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763280.2

ORF Insert Sequence:

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd4 ( XM_006237331.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237393.1 Rattus norvegicus Cd4 molecule (Cd4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa00691
Clone ID Related Accession (Same CDS sequence)	NM_012705.1 , XM_008763280.2 , XM_006237331.3
Accession Version	XM_006237331.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-cell surface glycoprotein CD4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237331.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237393.1
CDS	316..1689
Translation	MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNKLLIKGSLELYSRFDSRKNAWERGSFPLIINKLRMEDSQTYVCELENKKEEVELWVFRVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSKAFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFASTSITAYKSEGESAEFSFPLNLGEESLQGELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDRGILYQEVNLVVMKVTQPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQEKVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLNQTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI

Target ORF information:

RefSeq Version	XM_006237331.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237331.3

ORF Insert Sequence:

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG GTTCACTTGA GCTGTATAGT 
CGTTTTGATT CCAGAAAAAA TGCATGGGAG AGAGGATCAT TTCCCCTCAT CATCAATAAA 
CTTAGGATGG AGGACTCTCA GACTTATGTC TGCGAGCTGG AGAACAAGAA AGAGGAGGTG 
GAGTTGTGGG TCTTCAGAGT GACCTTCAAT CCGGGTACCA GACTGTTGCA GGGGCAGAGC 
CTGACCCTGA TCTTGGATAG CAACCCTAAG GTCTCTGACC CCCCGATAGA GTGCAAACAC 
AAAAGCAGTA ACATTGTCAA GGACTCCAAA GCTTTCTCCA CGCACAGCCT AAGGATTCAG 
GACAGTGGCA TCTGGAACTG CACCGTGACC CTGAACCAGA AGAAGCACTC ATTTGACATG 
AAACTCTCAG TGCTGGGCTT TGCGAGCACA TCCATCACGG CCTATAAGAG TGAGGGGGAG 
TCAGCGGAGT TCTCCTTCCC ACTCAACCTT GGAGAGGAAA GCCTGCAGGG AGAGTTGAGA 
TGGAAGGCAG AGAAGGCTCC TTCTTCCCAG TCCTGGATCA CCTTCTCCCT AAAGAACCAA 
AAGGTGTCTG TGCAGAAGTC TACTAGCAAC CCCAAGTTCC AGCTGTCCGA AACGCTCCCA 
CTCACCCTTC AGATACCCCA GGTCTCCCTT CAGTTTGCTG GTTCTGGCAA CCTGACCCTG 
ACTCTGGACA GAGGGATACT GTATCAGGAA GTGAACCTGG TGGTGATGAA AGTGACTCAG 
CCCGACAGCA ACACTTTGAC CTGTGAGGTG ATGGGACCCA CCTCACCCAA GATGAGACTG 
ATCTTGAAGC AGGAGAATCA GGAGGCCAGG GTCTCCAGGC AGGAGAAAGT GATTCAAGTG 
CAGGCCCCTG AAGCAGGGGT GTGGCAATGT CTACTGAGTG AAGGTGAAGA GGTCAAGATG 
GACTCCAAGA TCCAGGTTTT ATCCAAAGGG TTGAACCAGA CAATGTTCCT GGCTGTCGTG 
CTGGGGAGCG CCTTCAGCTT TCTGGTTTTC ACGGGGCTCT GCATCCTATT CTGTGTCAGG 
TGCCGGCACC AACAGCGCCA GGCAGCACGG ATGTCTCAGA TCAAGAGGCT TCTCAGTGAG 
AAGAAGACTT GCCAGTGCTC CCACCGGATG CAGAAAAGCC ACAATCTCAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd4 ( XM_006237333.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237395.1 Rattus norvegicus Cd4 molecule (Cd4), transcript variant X3, mRNA.

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CloneID	ORa27751
Clone ID Related Accession (Same CDS sequence)	XM_006237333.3
Accession Version	XM_006237333.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-cell surface glycoprotein CD4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237333.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG TGACCTTCAA TCCGGGTACC 
AGACTGTTGC AGGGGCAGAG CCTGACCCTG ATCTTGGATA GCAACCCTAA GGTCTCTGAC 
CCCCCGATAG AGTGCAAACA CAAAAGCAGT AACATTGTCA AGGACTCCAA AGCTTTCTCC 
ACGCACAGCC TAAGGATTCA GGACAGTGGC ATCTGGAACT GCACCGTGAC CCTGAACCAG 
AAGAAGCACT CATTTGACAT GAAACTCTCA GTGCTGGGCT TTGCGAGCAC ATCCATCACG 
GCCTATAAGA GTGAGGGGGA GTCAGCGGAG TTCTCCTTCC CACTCAACCT TGGAGAGGAA 
AGCCTGCAGG GAGAGTTGAG ATGGAAGGCA GAGAAGGCTC CTTCTTCCCA GTCCTGGATC 
ACCTTCTCCC TAAAGAACCA AAAGGTGTCT GTGCAGAAGT CTACTAGCAA CCCCAAGTTC 
CAGCTGTCCG AAACGCTCCC ACTCACCCTT CAGATACCCC AGGTCTCCCT TCAGTTTGCT 
GGTTCTGGCA ACCTGACCCT GACTCTGGAC AGAGGGATAC TGTATCAGGA AGTGAACCTG 
GTGGTGATGA AAGTGACTCA GCCCGACAGC AACACTTTGA CCTGTGAGGT GATGGGACCC 
ACCTCACCCA AGATGAGACT GATCTTGAAG CAGGAGAATC AGGAGGCCAG GGTCTCCAGG 
CAGGAGAAAG TGATTCAAGT GCAGGCCCCT GAAGCAGGGG TGTGGCAATG TCTACTGAGT 
GAAGGTGAAG AGGTCAAGAT GGACTCCAAG ATCCAGGTTT TATCCAAAGG GTTGAACCAG 
ACAATGTTCC TGGCTGTCGT GCTGGGGAGC GCCTTCAGCT TTCTGGTTTT CACGGGGCTC 
TGCATCCTAT TCTGTGTCAG GTGCCGGCAC CAACAGCGCC AGGCAGCACG GATGTCTCAG 
ATCAAGAGGC TTCTCAGTGA GAAGAAGACT TGCCAGTGCT CCCACCGGAT GCAGAAAAGC 
CACAATCTCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237395.1
CDS	235..1449
Translation	MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNKLLIKVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSKAFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFASTSITAYKSEGESAEFSFPLNLGEESLQGELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDRGILYQEVNLVVMKVTQPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQEKVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLNQTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI

Target ORF information:

RefSeq Version	XM_006237333.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd4 molecule (Cd4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237333.3

ORF Insert Sequence:

ATGTGCCGAG GCTTCTCTTT CAGGCACTTG CTGCCGCTGC TGCTCCTGCA GCTGTCAAAA 
CTCCTAGTTG TCACCCAAGG AAAGACCGTG GTGCTGGGGA AGGAAGGGGG TTCAGCAGAA 
CTGCCCTGTG AAAGTACCTC GAGGAGGAGT GCATCCTTCG CGTGGAAGTC CTCTGACCAA 
AAGACAATTC TGGGATATAA GAACAAGTTA TTGATTAAAG TGACCTTCAA TCCGGGTACC 
AGACTGTTGC AGGGGCAGAG CCTGACCCTG ATCTTGGATA GCAACCCTAA GGTCTCTGAC 
CCCCCGATAG AGTGCAAACA CAAAAGCAGT AACATTGTCA AGGACTCCAA AGCTTTCTCC 
ACGCACAGCC TAAGGATTCA GGACAGTGGC ATCTGGAACT GCACCGTGAC CCTGAACCAG 
AAGAAGCACT CATTTGACAT GAAACTCTCA GTGCTGGGCT TTGCGAGCAC ATCCATCACG 
GCCTATAAGA GTGAGGGGGA GTCAGCGGAG TTCTCCTTCC CACTCAACCT TGGAGAGGAA 
AGCCTGCAGG GAGAGTTGAG ATGGAAGGCA GAGAAGGCTC CTTCTTCCCA GTCCTGGATC 
ACCTTCTCCC TAAAGAACCA AAAGGTGTCT GTGCAGAAGT CTACTAGCAA CCCCAAGTTC 
CAGCTGTCCG AAACGCTCCC ACTCACCCTT CAGATACCCC AGGTCTCCCT TCAGTTTGCT 
GGTTCTGGCA ACCTGACCCT GACTCTGGAC AGAGGGATAC TGTATCAGGA AGTGAACCTG 
GTGGTGATGA AAGTGACTCA GCCCGACAGC AACACTTTGA CCTGTGAGGT GATGGGACCC 
ACCTCACCCA AGATGAGACT GATCTTGAAG CAGGAGAATC AGGAGGCCAG GGTCTCCAGG 
CAGGAGAAAG TGATTCAAGT GCAGGCCCCT GAAGCAGGGG TGTGGCAATG TCTACTGAGT 
GAAGGTGAAG AGGTCAAGAT GGACTCCAAG ATCCAGGTTT TATCCAAAGG GTTGAACCAG 
ACAATGTTCC TGGCTGTCGT GCTGGGGAGC GCCTTCAGCT TTCTGGTTTT CACGGGGCTC 
TGCATCCTAT TCTGTGTCAG GTGCCGGCAC CAACAGCGCC AGGCAGCACG GATGTCTCAG 
ATCAAGAGGC TTCTCAGTGA GAAGAAGACT TGCCAGTGCT CCCACCGGAT GCAGAAAAGC 
CACAATCTCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

C4d Deposition Reveals Myocardial Infarction After Cardiac Arrest--Experimental Study.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University24(3)393-9(2015 May-Jun)
Vuohelainen V,Paavonen T,Hamalainen M,Moilanen E,Mennander AA

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.
Journal of virology88(17)9934-46(2014 Sep)
Zhen A,Krutzik SR,Levin BR,Kasparian S,Zack JA,Kitchen SG

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence.
PLoS genetics7(11)e1002348(2011 Nov)
Nowell CS,Bredenkamp N,Tet?lin S,Jin X,Tischner C,Vaidya H,Sheridan JM,Stenhouse FH,Heussen R,Smith AJ,Blackburn CC

Loss of surface antigens is a conserved feature of apoptotic lymphocytes from several mammalian species.
Cellular immunology271(1)163-72(2011)
Diaz D,Chara L,Chevarria J,Ubeda M,Mu?oz L,Barcenilla H,S?nchez MA,Moreno Z,Monserrat J,Albillos A,Prieto A,Alvarez-Mon M

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Cd4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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