The following Ret gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ret cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa60751 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017592471.1 | |
| Accession Version | XM_017592471.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3321bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | proto-oncogene tyrosine-protein kinase receptor Ret isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCCTCCA CCAAGACACA GAGCGAGCAG ATGCCCGGTA GAGCAGCCCC GCTGGGTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017447960.1 |
| CDS | 144..3464 |
| Translation |
Target ORF information:
Target ORF information:
|
 XM_017592471.1 |
1 | ATGCCCTCCA CCAAGACACA GAGCGAGCAG ATGCCCGGTA GAGCAGCCCC GCTGGGTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa12188 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001110099.1 | |
| Accession Version | NM_001110099.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3222bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | proto-oncogene tyrosine-protein kinase receptor Ret isoform b precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07061871.1. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and unique C-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ299017.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001103569.1 |
| CDS | 14..3235 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001110099.1 |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa12231 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017592470.1 , NM_012643.2 | |
| Accession Version | NM_012643.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3348bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07061871.1. On Oct 23, 2007 this sequence version replaced NM_012643.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AJ299016.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036775.2 |
| CDS | 14..3361 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_012643.2 |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa12231 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017592470.1 , NM_012643.2 | |
| Accession Version | XM_017592470.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3348bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017447959.1 |
| CDS | 391..3738 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017592470.1 |
1 | ATGGCGAAAG CGAGGTCCGG CGCCGCAGGG CTGGGGCTGA AGCTGTTTTT GCTGCTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. |
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. |
Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. |
Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons. |
