Ppp2r2d cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ppp2r2d
Entrez Gene ID	246255
Full Name	protein phosphatase 2, regulatory subunit B, delta
General protein information	Preferred Names protein phosphatase 2, regulatory subunit B, delta Names serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform PP2A subunit B isoform B55-delta PP2A subunit B isoform PR55-delta PP2A subunit B isoform R2-delta PP2A subunit B isoform delta PP2A, subunit B, B-delta isoform PP2A, subunit B, B55-delta isoform PP2A, subunit B, PR55-delta isoform PP2A, subunit B, R2-delta isoform protein phosphatase 2, regulatory subunit B, delta isoform protein phosphatase 2A B regulatory subunit delta isoform
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q41
Summary	cytosolic regulatory subunit that modifies protein phosphatase type 2A activity and subcellular localization [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017588785.1	XP_017444274.1	serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
NM_144746.2	NP_653347.2	serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC558884	XP_001919558.4
Caenorhabditis elegans (roundworm)	sur-6	NP_492591.1
Arabidopsis thaliana (thale cress)	ATB BETA	NP_849681.1
Arabidopsis thaliana (thale cress)	B ALPHA	NP_974003.1
Oryza sativa (rice)	Os02g0224200	NP_001046333.1
Homo sapiens (human)	PPP2R2D	NP_060931.2
Canis lupus familiaris (dog)	PPP2R2D	XP_005637952.1
Rattus norvegicus (Norway rat)	Ppp2r2d	NP_653347.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004502	XP_313800.4
Drosophila melanogaster (fruit fly)	tws	NP_599113.1
Neurospora crassa	NCU09377	XP_963748.2
Oryza sativa (rice)	Os06g0563300	NP_001057879.1
Xenopus tropicalis (tropical clawed frog)	ppp2r2d	NP_001006697.1
Gallus gallus (chicken)	PPP2R2D	NP_001006507.1
Danio rerio (zebrafish)	ppp2r2bb	NP_001025293.2
Kluyveromyces lactis	KLLA0F09053g	XP_455492.1
Schizosaccharomyces pombe (fission yeast)	pab1	NP_592961.1
Magnaporthe oryzae (rice blast fungus)	MGG_05637	XP_003710525.1
Mus musculus (house mouse)	Ppp2r2d	NP_080667.1
Saccharomyces cerevisiae (baker's yeast)	CDC55	NP_011325.1
Eremothecium gossypii	AGOS_AFR195W	NP_985742.1

Gene Ontology
Bibliography

Related articles in PubMed

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.
Van Kanegan MJ, Strack S
Molecular and cellular biology29(3)662-74(2009 Feb)

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.
Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K
Proceedings of the National Academy of Sciences of the United States of America100(9)5107-12(2003 Apr)

Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A.
Strack S, Chang D, Zaucha JA, Colbran RJ, Wadzinski BE
FEBS letters460(3)462-6(1999 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Select PP2A heterotrimers oppose desensitization of the TrkA receptor tyrosine kinase, perhaps through dephosphorylation of inhibitory Ser/Thr phosphorylation sites on the receptor itself.
Title: The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.

The following Ppp2r2d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppp2r2d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02462	NM_144746.2 Latest version!	Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa56386	XM_017588785.1 Latest version!	Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ppp2r2d ( NM_144746.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_653347.2 Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), mRNA.

Price & Availability↑

CloneID	ORa02462
Clone ID Related Accession (Same CDS sequence)	NM_144746.2
Accession Version	NM_144746.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081720.1. On Jun 10, 2007 this sequence version replaced NM_144746.1. ##Evidence-Data-START## Transcript exon combination :: BC081720.1, AF180350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGAG CCGGAGGTGG CGGCTGCCCG ACGGGCGGCA ACGACTTCCA GTGGTGCTTC 
TCGCAGGTGA AGGGCGCTGT CGACGAGGAC GTGGCGGAAG CCGACATCAT CTCCACCGTT 
GAGTTTAACT ACTCTGGAGA CCTTCTTGCA ACAGGAGACA AAGGTGGCAG AGTTGTTATT 
TTCCAACGGG AACAAGAGAA TAAAGGCCGC GCTCACTCTA GGGGAGAGTA CAATGTTTAC 
AGTACCTTTC AGAGTCATGA GCCAGAGTTT GACTATTTGA AAAGTCTAGA AATTGAAGAA 
AAAATTAATA AAATCAGGTG GTTACCGCAA CAGAATGCTG CTCATTTTCT ACTCTCTACA 
AATGATAAAA CTATTAAATT ATGGAAAATA AGTGAACGAG ATAAAAGAGC AGAAGGTTAT 
AACTTGAAAG ATGAAGATGG ACGACTTCGA GACCCATTTA GAATTACGGC ACTACGGGTT 
CCAATATTGA AGCCCATGGA CCTTATGGTA GAAGCAAGTC CACGACGAAT TTTTGCAAAT 
GCTCATACAT ATCACATAAA TTCCATTTCA GTAAATAGTG ATCATGAAAC ATATCTCTCT 
GCAGATGATC TGAGAATTAA CCTATGGCAT TTAGAAATCA CAGATAGAAG CTTCAACATT 
GTGGACATCA AGCCTGCTAA CATGGAGGAG CTGACAGAAG TCATCACTGC CGCGGAGTTC 
CACCCACACC AGTGCAATGT ATTCGTCTAC AGCAGCAGCA AGGGGACCAT CAGGCTGTGT 
GACATGCGTT CTTCTGCCCT CTGTGATAGG CATGCCAAGT TTTTTGAAGA GCCAGAAGAT 
CCCAGCAGTA GATCCTTTTT CTCAGAAATA ATCTCATCTA TATCTGATGT CAAGTTCAGC 
CACAGTGGTC GATACATGAT GACCAGAGAC TATCTGTCGG TGAAGGTATG GGACCTCAAC 
ATGGAGGGCA GGCCTGTCGA GACCCACCAG GTACATGAGT ACCTACGAAG CAAGCTCTGC 
TCCTTGTATG AGAATGACTG CATCTTTGAC AAGTTCGAGT GCTGCTGGAA TGGTTCAGAC 
AGTGCCATTA TGACGGGGTC CTACAACAAC TTCTTTAGAA TGTTTGATAG AAACACTCGG 
AGGGATGTTA CACTGGAAGC CTCAAGAGAG AACAGCAAGC CCCGAGCCAG CCTGAAGCCC 
CGGAAAGTGT GTTCAGGGGG TAAGAGGAAG AAGGATGAGA TTAGCGTGGA CAGTTTGGAC 
TTCAATAAGA AGATCCTTCA CACAGCCTGG CACCCCATGG AGAGCATTAT TGCTGTAGCT 
GCCACCAATA ACTTGTATAT ATTCCAGGAC AAAATTAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653347.2
CDS	107..1468
Translation	MAGAGGGGCPTGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCSGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN

Target ORF information:

RefSeq Version	NM_144746.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144746.2

ORF Insert Sequence:

ATGGCAGGAG CCGGAGGTGG CGGCTGCCCG ACGGGCGGCA ACGACTTCCA GTGGTGCTTC 
TCGCAGGTGA AGGGCGCTGT CGACGAGGAC GTGGCGGAAG CCGACATCAT CTCCACCGTT 
GAGTTTAACT ACTCTGGAGA CCTTCTTGCA ACAGGAGACA AAGGTGGCAG AGTTGTTATT 
TTCCAACGGG AACAAGAGAA TAAAGGCCGC GCTCACTCTA GGGGAGAGTA CAATGTTTAC 
AGTACCTTTC AGAGTCATGA GCCAGAGTTT GACTATTTGA AAAGTCTAGA AATTGAAGAA 
AAAATTAATA AAATCAGGTG GTTACCGCAA CAGAATGCTG CTCATTTTCT ACTCTCTACA 
AATGATAAAA CTATTAAATT ATGGAAAATA AGTGAACGAG ATAAAAGAGC AGAAGGTTAT 
AACTTGAAAG ATGAAGATGG ACGACTTCGA GACCCATTTA GAATTACGGC ACTACGGGTT 
CCAATATTGA AGCCCATGGA CCTTATGGTA GAAGCAAGTC CACGACGAAT TTTTGCAAAT 
GCTCATACAT ATCACATAAA TTCCATTTCA GTAAATAGTG ATCATGAAAC ATATCTCTCT 
GCAGATGATC TGAGAATTAA CCTATGGCAT TTAGAAATCA CAGATAGAAG CTTCAACATT 
GTGGACATCA AGCCTGCTAA CATGGAGGAG CTGACAGAAG TCATCACTGC CGCGGAGTTC 
CACCCACACC AGTGCAATGT ATTCGTCTAC AGCAGCAGCA AGGGGACCAT CAGGCTGTGT 
GACATGCGTT CTTCTGCCCT CTGTGATAGG CATGCCAAGT TTTTTGAAGA GCCAGAAGAT 
CCCAGCAGTA GATCCTTTTT CTCAGAAATA ATCTCATCTA TATCTGATGT CAAGTTCAGC 
CACAGTGGTC GATACATGAT GACCAGAGAC TATCTGTCGG TGAAGGTATG GGACCTCAAC 
ATGGAGGGCA GGCCTGTCGA GACCCACCAG GTACATGAGT ACCTACGAAG CAAGCTCTGC 
TCCTTGTATG AGAATGACTG CATCTTTGAC AAGTTCGAGT GCTGCTGGAA TGGTTCAGAC 
AGTGCCATTA TGACGGGGTC CTACAACAAC TTCTTTAGAA TGTTTGATAG AAACACTCGG 
AGGGATGTTA CACTGGAAGC CTCAAGAGAG AACAGCAAGC CCCGAGCCAG CCTGAAGCCC 
CGGAAAGTGT GTTCAGGGGG TAAGAGGAAG AAGGATGAGA TTAGCGTGGA CAGTTTGGAC 
TTCAATAAGA AGATCCTTCA CACAGCCTGG CACCCCATGG AGAGCATTAT TGCTGTAGCT 
GCCACCAATA ACTTGTATAT ATTCCAGGAC AAAATTAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ppp2r2d ( XM_017588785.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444274.1 Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56386
Clone ID Related Accession (Same CDS sequence)	XM_017588785.1
Accession Version	XM_017588785.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTTA TGGTAGAAGC AAGTCCACGA CGAATTTTTG CAAATGCTCA TACATATCAC 
ATAAATTCCA TTTCAGTAAA TAGTGATCAT GAAACATATC TCTCTGCAGA TGATCTGAGA 
ATTAACCTAT GGCATTTAGA AATCACAGAT AGAAGCTTCA ACATTGTGGA CATCAAGCCT 
GCTAACATGG AGGAGCTGAC AGAAGTCATC ACTGCCGCGG AGTTCCACCC ACACCAGTGC 
AATGTATTCG TCTACAGCAG CAGCAAGGGG ACCATCAGGC TGTGTGACAT GCGTTCTTCT 
GCCCTCTGTG ATAGGCATGC CAAGTTTTTT GAAGAGCCAG AAGATCCCAG CAGTAGATCC 
TTTTTCTCAG AAATAATCTC ATCTATATCT GATGTCAAGT TCAGCCACAG TGGTCGATAC 
ATGATGACCA GAGACTATCT GTCGGTGAAG GTATGGGACC TCAACATGGA GGGCAGGCCT 
GTCGAGACCC ACCAGGTACA TGAGTACCTA CGAAGCAAGC TCTGCTCCTT GTATGAGAAT 
GACTGCATCT TTGACAAGTT CGAGTGCTGC TGGAATGGTT CAGACAGTGC CATTATGACG 
GGGTCCTACA ACAACTTCTT TAGAATGTTT GATAGAAACA CTCGGAGGGA TGTTACACTG 
GAAGCCTCAA GAGAGAACAG CAAGCCCCGA GCCAGCCTGA AGCCCCGGAA AGTGTGTTCA 
GGGGGTAAGA GGAAGAAGGA TGAGATTAGC GTGGACAGTT TGGACTTCAA TAAGAAGATC 
CTTCACACAG CCTGGCACCC CATGGAGAGC ATTATTGCTG TAGCTGCCAC CAATAACTTG 
TATATATTCC AGGACAAAAT TAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444274.1
CDS	1761..2627
Translation	MDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCSGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN

Target ORF information:

RefSeq Version	XM_017588785.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein phosphatase 2, regulatory subunit B, delta (Ppp2r2d), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588785.1

ORF Insert Sequence:

ATGGACCTTA TGGTAGAAGC AAGTCCACGA CGAATTTTTG CAAATGCTCA TACATATCAC 
ATAAATTCCA TTTCAGTAAA TAGTGATCAT GAAACATATC TCTCTGCAGA TGATCTGAGA 
ATTAACCTAT GGCATTTAGA AATCACAGAT AGAAGCTTCA ACATTGTGGA CATCAAGCCT 
GCTAACATGG AGGAGCTGAC AGAAGTCATC ACTGCCGCGG AGTTCCACCC ACACCAGTGC 
AATGTATTCG TCTACAGCAG CAGCAAGGGG ACCATCAGGC TGTGTGACAT GCGTTCTTCT 
GCCCTCTGTG ATAGGCATGC CAAGTTTTTT GAAGAGCCAG AAGATCCCAG CAGTAGATCC 
TTTTTCTCAG AAATAATCTC ATCTATATCT GATGTCAAGT TCAGCCACAG TGGTCGATAC 
ATGATGACCA GAGACTATCT GTCGGTGAAG GTATGGGACC TCAACATGGA GGGCAGGCCT 
GTCGAGACCC ACCAGGTACA TGAGTACCTA CGAAGCAAGC TCTGCTCCTT GTATGAGAAT 
GACTGCATCT TTGACAAGTT CGAGTGCTGC TGGAATGGTT CAGACAGTGC CATTATGACG 
GGGTCCTACA ACAACTTCTT TAGAATGTTT GATAGAAACA CTCGGAGGGA TGTTACACTG 
GAAGCCTCAA GAGAGAACAG CAAGCCCCGA GCCAGCCTGA AGCCCCGGAA AGTGTGTTCA 
GGGGGTAAGA GGAAGAAGGA TGAGATTAGC GTGGACAGTT TGGACTTCAA TAAGAAGATC 
CTTCACACAG CCTGGCACCC CATGGAGAGC ATTATTGCTG TAGCTGCCAC CAATAACTTG 
TATATATTCC AGGACAAAAT TAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.
Molecular and cellular biology29(3)662-74(2009 Feb)
Van Kanegan MJ,Strack S

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.
Proceedings of the National Academy of Sciences of the United States of America100(9)5107-12(2003 Apr)
Kabashima T,Kawaguchi T,Wadzinski BE,Uyeda K

Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A.
FEBS letters460(3)462-6(1999 Nov)
Strack S,Chang D,Zaucha JA,Colbran RJ,Wadzinski BE

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Ppp2r2d cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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