Myh3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Myh3
Entrez Gene ID	24583
Full Name	myosin heavy chain 3
Synonyms	Myhse,RNMHCG
General protein information	Preferred Names myosin heavy chain 3 Names myosin-3 myosin heavy chain, fast skeletal muscle, embryonic myosin heavy polypeptide 3 myosin, heavy chain 3, skeletal muscle, embryonic myosin, heavy polypeptide 3, skeletal muscle, embryonic
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24
Summary	heavy chain of myosin; involved in muscle contraction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012604.1	NP_036736.1	myosin-3

Pathways from BioSystems

Homologies

Homo sapiens (human)	MYH3	NP_002461.2
Pan troglodytes (chimpanzee)	MYH3	XP_003315696.1
Canis lupus familiaris (dog)	MYH3	NP_001107184.1
Mus musculus (house mouse)	Myh3	NP_001093105.1
	MYH3	XP_001114005.2
Rattus norvegicus (Norway rat)	Myh3	NP_036736.1
Bos taurus (cattle)	MYH3	NP_001095305.1
Xenopus tropicalis (tropical clawed frog)	LOC100495065	XP_002937051.2

Gene Ontology
Bibliography

Related articles in PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Embryonic myosin heavy-chain mutations cause distal arthrogryposis and developmental myosin myopathy that persists postnatally.
Tajsharghi H, Kimber E, Kroksmark AK, Jerre R, Tulinius M, Oldfors A
Archives of neurology65(8)1083-90(2008 Aug)

Developmental regulation of biglycan expression in muscle and tendon.
Lechner BE, Lim JH, Mercado ML, Fallon JR
Muscle & nerve34(3)347-55(2006 Sep)

Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome.
Toydemir RM, Rutherford A, Whitby FG, Jorde LB, Carey JC, Bamshad MJ
Nature genetics38(5)561-5(2006 May)

Insulin-like growth factor-I downregulates embryonic myosin heavy chain (eMyHC) in myoblast nuclei.
Rodgers BD
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society15(6)377-83(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IGF1 downregulates embryonic myosin heavy chain in myoblast nuclei [embryonic myosin heavy chain (eMyHC)]
Title: Insulin-like growth factor-I downregulates embryonic myosin heavy chain (eMyHC) in myoblast nuclei.

The following Myh3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myh3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00436	NM_012604.1 Latest version!	Rattus norvegicus myosin heavy chain 3 (Myh3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Myh3 ( NM_012604.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036736.1 Rattus norvegicus myosin heavy chain 3 (Myh3), mRNA.

Price & Availability↑

CloneID	ORa00436
Clone ID Related Accession (Same CDS sequence)	NM_012604.1
Accession Version	NM_012604.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5823bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	myosin-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X04267.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906352 [ECO:0000348] ##Evidence-Data-END##

ATGAGTAGCG ACACCGAGAT GGAAGTGTTT GGCATAGCTG CCCCTTTCCT CCGAAAGTCG 
GAAAAGGAGA GGATCGAAGC TCAGAACCAG CCCTTTGATG CCAAAACCTA TTGCTTTGTG 
GTTGACTCAA AGGAAGAATA TGCCAAGGGG AAAATTAAGA GTAGCCAGGA TGGGAAAGTC 
ACGGTGGAGA CAGAAGACAA CAGGACCCTG GTGGTTAAAC CAGAGGACGT GTATGCCATG 
AACCCTCCCA AGTTTGACAA GATCGAGGAC ATGGCCATGC TGACCCACCT GAACGAGCCT 
GCTGTGCTGT ACAACCTCAA GGACCGATAC ACGTCCTGGA TGATCTACAC CTATTCAGGC 
CTCTTCTGTG TCACCGTCAA CCCCTACAAG TGGTTGCCGG TGTACACCCC TGAGGTGGTG 
GATGGCTACC GAGGCAAAAA GCGCCAGGAG GCCCCGCCCC ACATCTTCTC CATCTCTGAC 
AACGCCTACC AGTTCATGCT GACGGATCGT GAGAACCAGT CCATCCTGAT CACCGGAGAA 
TCCGGGGCCG GGAAGACGGT GAACACCAAG CGTGTCATCC AGTACTTTGC AACAATTGCA 
GCCACTGGGG ACCTTGCCAA GAAGAAGGAC TCCAAAATGA AGGGGACCCT GGAAGATCAA 
ATCATCAGCG CCAACCCCCT GCTGGAGGCC TTTGGGAATG CCAAGACCGT GAGGAATGAC 
AACTCTTCCC GCTTTGGCAA GTTCATCCGC ATCCATTTCG GCACCACTGG GAAGCTGGCC 
TCTGCAGATA TTGAAACTTA TCTGCTGGAA AAGTCCAGAG TCACCTTCCA GCTGAAGGCT 
GAGAGAAGCT ATCACATCTT CTACCAGATT CTTTCCAACA AGAAGCCGGA ACTGATCGAG 
TTGCTGCTGA TTACGACCAA CCCTTACGAC TACCCATTCA TCAGCCAGGG TGAAATCCTG 
GTGGCCAGCA TCGATGATCG TGAGGAACTG TTGGCTACAG ACAGTGCCAT TGACATCCTG 
GGCTTCACCC CGGAGGAGAA ATCTGGACTC TATAAACTGA CAGGGGCTGT GATGCATTAT 
GGGAACATGA AGTTCAAGCA GAAGCAGCGA GAGGAGCAAG CTGAGCCAGA TGGCACCGAA 
GTGGCTGACA AAACAGCCTA CTTGATGGGC CTGAACTCTT CAGACCTCCT CAAAGCCTTG 
TGCTTTCCCA GAGTGAAAGT TGGGAATGAG TACGTTACAA AAGGCCAAAC TGTGGACCAG 
GTTCACCATG CTGTGAATGC TCTCTCCAAG TCCGTTTATG AGAAGCTGTT CTTGTGGATG 
GTCACTCGTA TTAACCAGCA GCTGGACACA AAGCTACCAA GACAACACTT CATTGGGGTT 
TTGGACATTG CGGGTTTTGA AATTTTTGAG TATAACAGCC TGGAGCAGCT GTGCATCAAC 
TTCACCAACG AGAAACTGCA ACAGTTTTTC AACCACCACA TGTTCGTGCT GGAGCAGGAG 
GAGTACAAGA AGGAAGGCAT CGAGTGGACC TTCATCGACT TCGGGATGGA CCTGGCGGCC 
TGCATCGAGC TCATCGAGAA GCCGATGGGC ATCTTCTCCA TCCTGGAAGA GGAGTGCATG 
TTCCCCAAGG CGACAGACAC CTCCTTCAAG AACAAGCTGT ATGACCAGCA CCTTGGAAAA 
TCCAACAACT TCCAGAAGCC TAAGGTGGTC AAAGGCAAGG CCGAGGCCCA CTTCTCCCTC 
ATCCACTATG CGGGCACCGT GGACTACAGT GTCTCGGGCT GGCTGGAGAA GAACAAGGAC 
CCCCTGAATG AGACCGTGGT GGGGCTGTAC CAGAAGTCTT CCAACAGACT CCTGGCCCAT 
CTCTATGCCA CCTTCGCTAC GACAGATGCT GACGGTGGGA AGAAGAAAGT CGCTAAGAAG 
AAAGGCTCTT CCTTCCAAAC AGTGTCTGCG CTGTTCAGGG AAAACTTGAA CAAGCTGATG 
TCCAATTTAA GAACCACTCA CCCACACTTT GTGCGCTGTA TAATACCCAA TGAAACCAAG 
ACCCCAGGGG CCATGGAACA CAGCCTGGTC CTGCACCAGC TGAGGTGTAA CGGGGTGCTA 
GAAGGCATCC GCATCTGCAG GAAGGGGTTC CCCAACAGGA TTCTGTATGG AGACTTTAAA 
CAGAGATACC GAGTGCTGAA CGCCAGTGCC ATCCCGGAGG GCCAGTTCAT TGACAGCAAG 
AAAGCTTGCG AGAAGCTCTT GGCTTCCATT GACATCGACC ACACACAGTA CAAATTTGGA 
CACACCAAGG TGTTCTTTAA GGCTGGCTTG CTGGGAACCC TGGAGGAGAT GCGGGATGAG 
CGTCTGGCCA AACTGATCAC TCGGACACAA GCCGTGTGCA GAGGGTTCCT CATGCGTGTG 
GAATTCCAGA AGATGATGCA GAGGAGGGAA TCCATCTTCT GCATCCAGTA CAACATCCGC 
GCCTTCATGA ACGTCAAGCA CTGGCCCTGG ATGAAACTCT TCTTCAAGAT CAAGCCCCTG 
CTGAAGAGCG CCGAGACGGA GAAGGAGATG GCCACCATGA AGGAGGAGTT CCAGAAGACC 
AAGGACGAGC TCGCCAAGTC GGAGGCAAAG AGGAAGGAGC TGGAGGAGAA GCTGGTCACT 
CTGGTACAAG AGAAGAACGA CCTGCAGCTC CAAGTACAGG CGGAGAGTGA GAATTTGCTG 
GATGCCGAGG AGCGATGCGA CCAGCTGATC AAAGCCAAGT TCCAGCTGGA GGCCAAAATT 
AAAGAGGTGA CCGAAAGAGC TGAGGATGAG GAGGAGATCA ACGCCGAGCT CACGGCCAAG 
AAGAGGAAGC TGGAGGACGA GTGCTCGGAG CTGAAGAAGG ACATCGATGA CCTTGAGCTG 
ACACTGGCCA AGGTTGAGAA GGAGAAGCAC GCCACGGAGA ACAAGGTAAA AAACCTTACC 
GAAGAACTGG CAGGCCTGGA TGAAACTATT GCAAAGCTAA CACGGGAGAA GAAGGCCCTC 
CAAGAGGCCC ACCAGCAGAC CCTGGACGAC CTCCAGGCTG AGGAAGACAA GGTCAATTCT 
CTGAGCAAGC TCAAGAGCAA GCTGGAGCAG CAAGTGGATG ATTTGGAGAG CTCCCTCGAA 
CAAGAGAAGA AGCTGCGTGT GGACCTGGAA AGGAACAAGA GGAAGCTGGA GGGAGACCTG 
AAGCTTGCCC AAGAGTCCAT ATTAGATCTG GAGAACGACA AGCAACAGCT GGACGAGAGG 
CTCAAGAAGA AGGACTTTGA ATATAGCCAG CTGCAGAGCA AGGTGGAAGA TGAGCAGACG 
CTGAGCCTCC AACTTCAGAA GAAAATCAAA GAGTTACAGG CCCGCATTGA GGAGCTGGAG 
GAAGAGATAG AGGCGGAGAG GGCCACCCGG GCCAAGACAG AGAAGCAGCG CAGCGACTAC 
GCCCGCGAGC TGGAGGAGCT GAGTGAACGT CTGGAGGAGG CGGGCGGTGT CACCTCTACC 
CAGATTGAGC TGAACAAGAA GCGTGAGGCT GAGTTCTTGA AGCTGCGCAG GGACCTGGAG 
GAGGCCACCC TGCAGCACGA GGCCACCGTG GCCACGCTGC GGAAGAAGCA CGCGGACAGC 
GCGGCGGAGC TGGCAGAGCA GATCGACAAC CTGCAGCGCG TCAAGCAGAA GCTGGAGAAG 
GAGAAGAGCG AGTTCAAGCT GGAGATCGAC GACCTCTCCA GCAGTGTGGA GAGTGTGTCC 
AAATCCAAGG CCAACCTGGA GAAGATATGC CGAACTCTAG AGGATCAGTT AAGCGAGGCC 
AGGGGCAAGA ACGAGGAGAC GCAGAGAAGC CTAAGTGAGC TGACCACACA GAAGTCCCGG 
CTGCAGACAG AAGCGGGTGA GCTGAGTCGT CAACTGGAAG AAAAGGAAAG CATAGTATCT 
CAGCTTTCCA GGAGCAAGCA AGCCTTTACC CAACAGATAG AGGAGCTCAA GAGGCAACTG 
GAGGAAGAGA ACAAGGCCAA GAATGCGCTG GCCCACGCCC TGCAGTCCTC CCGCCACGAC 
TGTGACCTGC TTCGGGAACA GTACGAGGAG GAGCAGGAAG GCAAAGCCGA GCTGCAGAGG 
GCGCTGTCCA AGGCCAACAG CGAGGTGGCC CAATGGAGGA CCAAATATGA GACGGATGCC 
ATCCAGCGCA CGGAGGAGCT GGAGGAGGCC AAAAAAAAGC TTGCTCAGCG CCTTCAGGAT 
TCGGAGGAGC AGGTCGAGGC TGTGAATGCA AAATGCGCTT CCTTGGAAAA GACCAAGCAG 
AGGCTGCAAG GGGAGGTGGA GGACTTGATG GTGGATGTGG AGAGAGCCAA CTCTCTGGCT 
GCCGCTCTGG ACAAGAAGCA GAGGAACTTT GACAAGGTGT TAGCCGAGTG GAAGACGAAG 
TGTGAGGAGA GCCAAGCAGA GCTGGAGGCG GCTCTCAAGG AATCCCGGTC CTTGAGCACT 
GAGCTCTTCA AACTGAAAAA CGCCTATGAA GAAGCCTTGG ATCAACTCGA AACTGTGAAG 
CGAGAGAATA AGAACTTAGA ACAAGAGATA GCAGATCTCA CCGAACAAAT TGCTGAGAAC 
GGTAAAAGCA TCCACGAGCT AGAGAAATCC AGAAAGCAGA TGGAGCTGGA GAAGGCTGAT 
ATCCAGATGG CGCTGGAGGA AGCAGAGGCA GCTCTGGAGC ACGAAGAAGC CAAGATCCTC 
AGGATCCAGC TTGAACTGAC GCAGGTGAAA TCAGAGATCG ATAGAAAGAT CGCAGAGAAG 
GATGAAGAGA TCGAGCAGCT GAAGAGGAAC TACCAGAGGA CAGTGGAGAC CATGCAGGGC 
GCCCTGGATG CTGAGGTGCG CAGCAGGAAT GAGGCGATCC GGCTGAAGAA GAAGATGGAG 
GGCGACCTCA ATGAGATTGA GATCCAGCTG AGCCATGCCA ACCGCCAGGC CGCAGAGACC 
ATCAAGCACC TCCGGAGTGT CCAGGGACAG CTGAAGGACA CCCAGCTGCA CCTGGATGAC 
GCTCTCCGAG GCCAGGAGGA CCTGAAGGAG CAGCTGGCGA TCGTGGAGCG CAGAGCCAAC 
CTGCTGCAGG CTGAGGTGGA GGAGCTGCGG GCCACTCTGG AGCAGACGGA GAGGGCCCGG 
AAGCTGGCAG AGCAGGAGCT GCTGGACTCC AACGAGAGGG TTCAGCTGCT GCACACCCAG 
AACACCAGCC TCATCCACAC CAAGAAGAAG TTGGAGACTG ACCTCACACA GCTCCAGAGT 
GAGGTGGAGG ATGCCAGCAG GGACGCAAGG AACGCCGAGG AGAAGGCCAA AAAGGCCATC 
ACTGATGCCG CCATGATGGC GGAGGAGCTA AAGAAGGAGC AGGACACCAG CGCCCATCTG 
GAGCGGATGA AGAAGAACCT GGAGCAGACG GTGAAGGACC TGCAGCACCG TCTGGACGAG 
GCTGAGCAGC TGGCACTGAA GGGCGGCAAG AAGCAGATCC AGAAACTGGA GACGAGGATC 
AGAGAGCTAG AGTTTGAGCT GGAAGGGGAA CAGAAGAGGA ACACAGAGTC TGTGAAGGGC 
CTGAGGAAGT ATGAGCGGCG TGTCAAGGAG CTCACCTACC AGAGTGAGGA GGACAGGAAG 
AATGTGCTGA GATTGCAGGA TCTGGTGGAT AAACTTCAAG TGAAAGTCAA GTCCTACAAG 
AGGCAGGCTG AGGAGGCTGA TGAACAAGCC AATGTTCATC TCACCAAGTT CCGGAAAGCC 
CAGCATGAGC TAGAGGAGGC CGAGGAACGT GCGGATATTG CAGAATCGCA AGTCAATAAA 
CTGCGGGCTA AAACCCGGGA CTTCACCTCT AGCCGGATGG TGGTCCATGA AAGTGAGGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036736.1
CDS	91..5913
Translation	MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDKIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYTPEVVDGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGKAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATTDADGGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFLMRVEFQKMMQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEETQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANVHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE

Target ORF information:

RefSeq Version	NM_012604.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myosin heavy chain 3 (Myh3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012604.1

ORF Insert Sequence:

ATGAGTAGCG ACACCGAGAT GGAAGTGTTT GGCATAGCTG CCCCTTTCCT CCGAAAGTCG 
GAAAAGGAGA GGATCGAAGC TCAGAACCAG CCCTTTGATG CCAAAACCTA TTGCTTTGTG 
GTTGACTCAA AGGAAGAATA TGCCAAGGGG AAAATTAAGA GTAGCCAGGA TGGGAAAGTC 
ACGGTGGAGA CAGAAGACAA CAGGACCCTG GTGGTTAAAC CAGAGGACGT GTATGCCATG 
AACCCTCCCA AGTTTGACAA GATCGAGGAC ATGGCCATGC TGACCCACCT GAACGAGCCT 
GCTGTGCTGT ACAACCTCAA GGACCGATAC ACGTCCTGGA TGATCTACAC CTATTCAGGC 
CTCTTCTGTG TCACCGTCAA CCCCTACAAG TGGTTGCCGG TGTACACCCC TGAGGTGGTG 
GATGGCTACC GAGGCAAAAA GCGCCAGGAG GCCCCGCCCC ACATCTTCTC CATCTCTGAC 
AACGCCTACC AGTTCATGCT GACGGATCGT GAGAACCAGT CCATCCTGAT CACCGGAGAA 
TCCGGGGCCG GGAAGACGGT GAACACCAAG CGTGTCATCC AGTACTTTGC AACAATTGCA 
GCCACTGGGG ACCTTGCCAA GAAGAAGGAC TCCAAAATGA AGGGGACCCT GGAAGATCAA 
ATCATCAGCG CCAACCCCCT GCTGGAGGCC TTTGGGAATG CCAAGACCGT GAGGAATGAC 
AACTCTTCCC GCTTTGGCAA GTTCATCCGC ATCCATTTCG GCACCACTGG GAAGCTGGCC 
TCTGCAGATA TTGAAACTTA TCTGCTGGAA AAGTCCAGAG TCACCTTCCA GCTGAAGGCT 
GAGAGAAGCT ATCACATCTT CTACCAGATT CTTTCCAACA AGAAGCCGGA ACTGATCGAG 
TTGCTGCTGA TTACGACCAA CCCTTACGAC TACCCATTCA TCAGCCAGGG TGAAATCCTG 
GTGGCCAGCA TCGATGATCG TGAGGAACTG TTGGCTACAG ACAGTGCCAT TGACATCCTG 
GGCTTCACCC CGGAGGAGAA ATCTGGACTC TATAAACTGA CAGGGGCTGT GATGCATTAT 
GGGAACATGA AGTTCAAGCA GAAGCAGCGA GAGGAGCAAG CTGAGCCAGA TGGCACCGAA 
GTGGCTGACA AAACAGCCTA CTTGATGGGC CTGAACTCTT CAGACCTCCT CAAAGCCTTG 
TGCTTTCCCA GAGTGAAAGT TGGGAATGAG TACGTTACAA AAGGCCAAAC TGTGGACCAG 
GTTCACCATG CTGTGAATGC TCTCTCCAAG TCCGTTTATG AGAAGCTGTT CTTGTGGATG 
GTCACTCGTA TTAACCAGCA GCTGGACACA AAGCTACCAA GACAACACTT CATTGGGGTT 
TTGGACATTG CGGGTTTTGA AATTTTTGAG TATAACAGCC TGGAGCAGCT GTGCATCAAC 
TTCACCAACG AGAAACTGCA ACAGTTTTTC AACCACCACA TGTTCGTGCT GGAGCAGGAG 
GAGTACAAGA AGGAAGGCAT CGAGTGGACC TTCATCGACT TCGGGATGGA CCTGGCGGCC 
TGCATCGAGC TCATCGAGAA GCCGATGGGC ATCTTCTCCA TCCTGGAAGA GGAGTGCATG 
TTCCCCAAGG CGACAGACAC CTCCTTCAAG AACAAGCTGT ATGACCAGCA CCTTGGAAAA 
TCCAACAACT TCCAGAAGCC TAAGGTGGTC AAAGGCAAGG CCGAGGCCCA CTTCTCCCTC 
ATCCACTATG CGGGCACCGT GGACTACAGT GTCTCGGGCT GGCTGGAGAA GAACAAGGAC 
CCCCTGAATG AGACCGTGGT GGGGCTGTAC CAGAAGTCTT CCAACAGACT CCTGGCCCAT 
CTCTATGCCA CCTTCGCTAC GACAGATGCT GACGGTGGGA AGAAGAAAGT CGCTAAGAAG 
AAAGGCTCTT CCTTCCAAAC AGTGTCTGCG CTGTTCAGGG AAAACTTGAA CAAGCTGATG 
TCCAATTTAA GAACCACTCA CCCACACTTT GTGCGCTGTA TAATACCCAA TGAAACCAAG 
ACCCCAGGGG CCATGGAACA CAGCCTGGTC CTGCACCAGC TGAGGTGTAA CGGGGTGCTA 
GAAGGCATCC GCATCTGCAG GAAGGGGTTC CCCAACAGGA TTCTGTATGG AGACTTTAAA 
CAGAGATACC GAGTGCTGAA CGCCAGTGCC ATCCCGGAGG GCCAGTTCAT TGACAGCAAG 
AAAGCTTGCG AGAAGCTCTT GGCTTCCATT GACATCGACC ACACACAGTA CAAATTTGGA 
CACACCAAGG TGTTCTTTAA GGCTGGCTTG CTGGGAACCC TGGAGGAGAT GCGGGATGAG 
CGTCTGGCCA AACTGATCAC TCGGACACAA GCCGTGTGCA GAGGGTTCCT CATGCGTGTG 
GAATTCCAGA AGATGATGCA GAGGAGGGAA TCCATCTTCT GCATCCAGTA CAACATCCGC 
GCCTTCATGA ACGTCAAGCA CTGGCCCTGG ATGAAACTCT TCTTCAAGAT CAAGCCCCTG 
CTGAAGAGCG CCGAGACGGA GAAGGAGATG GCCACCATGA AGGAGGAGTT CCAGAAGACC 
AAGGACGAGC TCGCCAAGTC GGAGGCAAAG AGGAAGGAGC TGGAGGAGAA GCTGGTCACT 
CTGGTACAAG AGAAGAACGA CCTGCAGCTC CAAGTACAGG CGGAGAGTGA GAATTTGCTG 
GATGCCGAGG AGCGATGCGA CCAGCTGATC AAAGCCAAGT TCCAGCTGGA GGCCAAAATT 
AAAGAGGTGA CCGAAAGAGC TGAGGATGAG GAGGAGATCA ACGCCGAGCT CACGGCCAAG 
AAGAGGAAGC TGGAGGACGA GTGCTCGGAG CTGAAGAAGG ACATCGATGA CCTTGAGCTG 
ACACTGGCCA AGGTTGAGAA GGAGAAGCAC GCCACGGAGA ACAAGGTAAA AAACCTTACC 
GAAGAACTGG CAGGCCTGGA TGAAACTATT GCAAAGCTAA CACGGGAGAA GAAGGCCCTC 
CAAGAGGCCC ACCAGCAGAC CCTGGACGAC CTCCAGGCTG AGGAAGACAA GGTCAATTCT 
CTGAGCAAGC TCAAGAGCAA GCTGGAGCAG CAAGTGGATG ATTTGGAGAG CTCCCTCGAA 
CAAGAGAAGA AGCTGCGTGT GGACCTGGAA AGGAACAAGA GGAAGCTGGA GGGAGACCTG 
AAGCTTGCCC AAGAGTCCAT ATTAGATCTG GAGAACGACA AGCAACAGCT GGACGAGAGG 
CTCAAGAAGA AGGACTTTGA ATATAGCCAG CTGCAGAGCA AGGTGGAAGA TGAGCAGACG 
CTGAGCCTCC AACTTCAGAA GAAAATCAAA GAGTTACAGG CCCGCATTGA GGAGCTGGAG 
GAAGAGATAG AGGCGGAGAG GGCCACCCGG GCCAAGACAG AGAAGCAGCG CAGCGACTAC 
GCCCGCGAGC TGGAGGAGCT GAGTGAACGT CTGGAGGAGG CGGGCGGTGT CACCTCTACC 
CAGATTGAGC TGAACAAGAA GCGTGAGGCT GAGTTCTTGA AGCTGCGCAG GGACCTGGAG 
GAGGCCACCC TGCAGCACGA GGCCACCGTG GCCACGCTGC GGAAGAAGCA CGCGGACAGC 
GCGGCGGAGC TGGCAGAGCA GATCGACAAC CTGCAGCGCG TCAAGCAGAA GCTGGAGAAG 
GAGAAGAGCG AGTTCAAGCT GGAGATCGAC GACCTCTCCA GCAGTGTGGA GAGTGTGTCC 
AAATCCAAGG CCAACCTGGA GAAGATATGC CGAACTCTAG AGGATCAGTT AAGCGAGGCC 
AGGGGCAAGA ACGAGGAGAC GCAGAGAAGC CTAAGTGAGC TGACCACACA GAAGTCCCGG 
CTGCAGACAG AAGCGGGTGA GCTGAGTCGT CAACTGGAAG AAAAGGAAAG CATAGTATCT 
CAGCTTTCCA GGAGCAAGCA AGCCTTTACC CAACAGATAG AGGAGCTCAA GAGGCAACTG 
GAGGAAGAGA ACAAGGCCAA GAATGCGCTG GCCCACGCCC TGCAGTCCTC CCGCCACGAC 
TGTGACCTGC TTCGGGAACA GTACGAGGAG GAGCAGGAAG GCAAAGCCGA GCTGCAGAGG 
GCGCTGTCCA AGGCCAACAG CGAGGTGGCC CAATGGAGGA CCAAATATGA GACGGATGCC 
ATCCAGCGCA CGGAGGAGCT GGAGGAGGCC AAAAAAAAGC TTGCTCAGCG CCTTCAGGAT 
TCGGAGGAGC AGGTCGAGGC TGTGAATGCA AAATGCGCTT CCTTGGAAAA GACCAAGCAG 
AGGCTGCAAG GGGAGGTGGA GGACTTGATG GTGGATGTGG AGAGAGCCAA CTCTCTGGCT 
GCCGCTCTGG ACAAGAAGCA GAGGAACTTT GACAAGGTGT TAGCCGAGTG GAAGACGAAG 
TGTGAGGAGA GCCAAGCAGA GCTGGAGGCG GCTCTCAAGG AATCCCGGTC CTTGAGCACT 
GAGCTCTTCA AACTGAAAAA CGCCTATGAA GAAGCCTTGG ATCAACTCGA AACTGTGAAG 
CGAGAGAATA AGAACTTAGA ACAAGAGATA GCAGATCTCA CCGAACAAAT TGCTGAGAAC 
GGTAAAAGCA TCCACGAGCT AGAGAAATCC AGAAAGCAGA TGGAGCTGGA GAAGGCTGAT 
ATCCAGATGG CGCTGGAGGA AGCAGAGGCA GCTCTGGAGC ACGAAGAAGC CAAGATCCTC 
AGGATCCAGC TTGAACTGAC GCAGGTGAAA TCAGAGATCG ATAGAAAGAT CGCAGAGAAG 
GATGAAGAGA TCGAGCAGCT GAAGAGGAAC TACCAGAGGA CAGTGGAGAC CATGCAGGGC 
GCCCTGGATG CTGAGGTGCG CAGCAGGAAT GAGGCGATCC GGCTGAAGAA GAAGATGGAG 
GGCGACCTCA ATGAGATTGA GATCCAGCTG AGCCATGCCA ACCGCCAGGC CGCAGAGACC 
ATCAAGCACC TCCGGAGTGT CCAGGGACAG CTGAAGGACA CCCAGCTGCA CCTGGATGAC 
GCTCTCCGAG GCCAGGAGGA CCTGAAGGAG CAGCTGGCGA TCGTGGAGCG CAGAGCCAAC 
CTGCTGCAGG CTGAGGTGGA GGAGCTGCGG GCCACTCTGG AGCAGACGGA GAGGGCCCGG 
AAGCTGGCAG AGCAGGAGCT GCTGGACTCC AACGAGAGGG TTCAGCTGCT GCACACCCAG 
AACACCAGCC TCATCCACAC CAAGAAGAAG TTGGAGACTG ACCTCACACA GCTCCAGAGT 
GAGGTGGAGG ATGCCAGCAG GGACGCAAGG AACGCCGAGG AGAAGGCCAA AAAGGCCATC 
ACTGATGCCG CCATGATGGC GGAGGAGCTA AAGAAGGAGC AGGACACCAG CGCCCATCTG 
GAGCGGATGA AGAAGAACCT GGAGCAGACG GTGAAGGACC TGCAGCACCG TCTGGACGAG 
GCTGAGCAGC TGGCACTGAA GGGCGGCAAG AAGCAGATCC AGAAACTGGA GACGAGGATC 
AGAGAGCTAG AGTTTGAGCT GGAAGGGGAA CAGAAGAGGA ACACAGAGTC TGTGAAGGGC 
CTGAGGAAGT ATGAGCGGCG TGTCAAGGAG CTCACCTACC AGAGTGAGGA GGACAGGAAG 
AATGTGCTGA GATTGCAGGA TCTGGTGGAT AAACTTCAAG TGAAAGTCAA GTCCTACAAG 
AGGCAGGCTG AGGAGGCTGA TGAACAAGCC AATGTTCATC TCACCAAGTT CCGGAAAGCC 
CAGCATGAGC TAGAGGAGGC CGAGGAACGT GCGGATATTG CAGAATCGCA AGTCAATAAA 
CTGCGGGCTA AAACCCGGGA CTTCACCTCT AGCCGGATGG TGGTCCATGA AAGTGAGGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Embryonic myosin heavy-chain mutations cause distal arthrogryposis and developmental myosin myopathy that persists postnatally.
Archives of neurology65(8)1083-90(2008 Aug)
Tajsharghi H,Kimber E,Kroksmark AK,Jerre R,Tulinius M,Oldfors A

Developmental regulation of biglycan expression in muscle and tendon.
Muscle & nerve34(3)347-55(2006 Sep)
Lechner BE,Lim JH,Mercado ML,Fallon JR

Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome.
Nature genetics38(5)561-5(2006 May)
Toydemir RM,Rutherford A,Whitby FG,Jorde LB,Carey JC,Bamshad MJ

Insulin-like growth factor-I downregulates embryonic myosin heavy chain (eMyHC) in myoblast nuclei.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society15(6)377-83(2005 Dec)
Rodgers BD

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Myh3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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