Muc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Muc1
Entrez Gene ID	24571
Full Name	mucin 1, cell surface associated
General protein information	Preferred Names mucin 1, cell surface associated Names mucin-1 Mucin1 mucin 1, transmembrane
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	an integral membrane protein whose reduction is necessary for embryo implantation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012602.1	NP_036734.1	mucin-1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Muc1	NP_036734.1
Mus musculus (house mouse)	Muc1	NP_038633.1

Gene Ontology
Bibliography

Related articles in PubMed

Changes in pulmonary tissue structure and KL-6/MUC1 expression in a newborn rat model of hyperoxia-induced bronchopulmonary dysplasia.
Zhu Y, Fu J, You K, Jin L, Wang M, Lu D, Xue X
Experimental lung research39(10)417-26(2013 Dec)

Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model.
Ghosh SK, Uchida M, Yoo B, Ross AW, Gendler SJ, Gong J, Moore A, Medarova Z
International journal of cancer132(8)1860-7(2013 Apr)

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.
Kirby A, Gnirke A, Jaffe DB, Bare?ov? V, Pochet N, Blumenstiel B, Ye C, Aird D, Stevens C, Robinson JT, Cabili MN, Gat-Viks I, Kelliher E, Daza R, DeFelice M, H?lkov? H, Sovov? J, Vylet'al P, Antignac C, Guttman M, Handsaker RE, Perrin D, Steelman S, Sigurdsson S, Scheinman SJ, Sougnez C, Cibulskis K, Parkin M, Green T, Rossin E, Zody MC, Xavier RJ, Pollak MR, Alper SL, Lindblad-Toh K, Gabriel S, Hart PS, Regev A, Nusbaum C, Kmoch S, Bleyer AJ, Lander ES, Daly MJ
Nature genetics45(3)299-303(2013 Mar)

Novel biomarkers of arterial and venous ischemia in microvascular flaps.
Nguyen GK, Hwang BH, Zhang Y, Monahan JF, Davis GB, Lee YS, Ragina NP, Wang C, Zhou ZY, Hong YK, Spivak RM, Wong AK
PloS one8(8)e71628(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increased lung MUC1 expression appears to be closely associated with impairment of alveolarization in a newborn model of hyperoxia-induced bronchopulmonary dysplasia.
Title: Changes in pulmonary tissue structure and KL-6/MUC1 expression in a newborn rat model of hyperoxia-induced bronchopulmonary dysplasia.

Muc1 expression was localized in the mammary gland ductus and branching ductus.
Title: [Expressions of Sca-1, CD24 and Muc1 in quiescent mammary glands of female rats].

We identified novel cell surface markers specific for hepatic progenitor/oval cells. Six are unique for the adult progenitors (CD133, claudin-7, cadherin 22, mucin-1, ros-1, Gabrp).
Title: Novel hepatic progenitor cell surface markers in the adult rat liver.

The effect of geranylgeranylacetone on the expression of MUC1, MUC5AC, and MUC6 in ethanol-treated rats is reported.
Title: Gastric mucosal protection via enhancement of MUC5AC and MUC6 by geranylgeranylacetone.

Expression of MUC1 in 3Y1 cells activates the anti-apoptotic PI3K/Akt and Bcl-x(L) pathways.
Title: The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts.

The following Muc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Muc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00431	NM_012602.1 Latest version!	Rattus norvegicus mucin 1, cell surface associated (Muc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Muc1 ( NM_012602.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036734.1 Rattus norvegicus mucin 1, cell surface associated (Muc1), mRNA.

Price & Availability↑

CloneID	ORa00431
Clone ID Related Accession (Same CDS sequence)	NM_012602.1
Accession Version	NM_012602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Rattus norvegicus(Norway rat)
Product	mucin-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC166505.1. On or before Aug 15, 2008 this sequence version replaced XM_001074423.1, XM_342281.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGACCCCGG GCATACGGGT TCCTCTCCTC CTGCTGCTAC TTCTAGCAAG CCTAAAAGTC 
CGCAGTGGTG CCTCCTCCTC AACCACCAGC CTTCCAGGGG ACTCCTTCAG CACTGCAGTC 
CCCAGTGGTG CCTCTTCCTC AGCCACCAGC CCTCCAGTGG ACTCCACCAC CTCTCCAGTT 
CATAGTAGCA CCTCGTTCCC AGCCACCAGC CCTCCAGGAG ACTCCACCAG CACTGCAGTC 
CTCAGTGGTG ACTCAGATCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
CCCAATGGTG CCTCTTCCTC AGCCACCAGC CCTCCAGTGG ACTCCACCAC CTCCCCAGTT 
CATAGTAGCA CCTCGTTCCC AGCCACCAGC TCTCCAGGGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCTTCCTC AGCCACCAGC CCTCCAGAGG ACTCCTCCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTATATTGG ACTCCTCCAG CACTGCAGTC 
CTCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGAGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGAGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTATATTGG ACTCCTCCAG CACTGCAATC 
CACAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
CTCAGCGGTG CTTCCACCCA AACCACCAAG GCTGTATCAG ACTTAGCTAG CACTCCAACC 
CACAATGGCA TCATGGTCCC AACTACCTGG TCTGCATTGA GCTCAGCCAC CAGTCCGGTG 
TACAGTGGTT CCTCAGCTAC AACTAATAGC TCTGAATCAG ACATGGCCAC CACTCCAGTG 
TACAGTGGCA CCCCATTCTC TTCTACCACG GCTACGTCAG CTATCACCCC AGACCACAAT 
GGCTCCTTGG TGCGAACTAC CAGTTCTGTG TTGGGCTTAG CCACCAGTCC AGCCCATGAT 
ACCTCTGCGG TGGCCACAAC TCCAGTCCGC AATGACACTC AGTCTTCAGT TCCAAGTCAG 
CAGCCCATCT CTCCCACCAT CCCCGCCATC TCCAGCCACA GTACTGTTAG CAGCAGCTCT 
TACTACAGCA CAGCGGTCTT CCCTACCTTC TCCAGTAACA GCTCACCCCA GTTGTCTGTC 
GGGGTCTCCT TCTTCTCGTT GTCTTTTTAC ATTCGGAACC ACCCATTTAA TTCTTCCCTG 
GAAGACCCCA GCTCCCGCTA CTACCAAGAA CTGAAGAGGA ACATTTCCGG ATTGTTTCTG 
CAGGTTTTTA ACGGAGACTT TCTGGGGGTC TCTACTATCA AGTTCAGGTC AGGCTCGGTG 
GTGGTAGCAT CGACTGTGAT TTTCCGGGAG GGCACTTTCA GTGCCTCTGA AGTGAAGTCA 
CAGCTCGTAC AACATAAGAA GGAGGCAGCT GACTATAATC TGACTATCTC GGAAGTCAAT 
GTGAATGAGA TGCAGTTCCC TTCCTCTGCC CAGTCTTGGC CTGGGGTACC AGGTTGGGGC 
ATTGCCCTGC TGGTACTGGT CTGTATTTTG GTGGCTTTGG TCATCGTCTA TCTCATTGCC 
CTGGCATTGT GCCAGTGCCG CAGAAAGAGC TATGGGCAGC TGGACCTCTT TCCAACCCGG 
GACACCTACC ATCCTATGAG TGAATATCCT ACCTACCACA CTCACGGACG CTATGTGCCC 
CCTGCCACTA CCAAACGTAG CCCCTATGAA GAGGTTTCGA CAGGCAATGG CAGTAGCGGT 
CTCTCTTACA CCAACCCGGC TGTGGCAACC ACTTCGGCCA ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036734.1
CDS	56..2023
Translation	MTPGIRVPLLLLLLLASLKVRSGASSSTTSLPGDSFSTAVPSGASSSATSPPVDSTTSPVHSSTSFPATSPPGDSTSTAVLSGDSDPATSPPGDSSSTAVPNGASSSATSPPVDSTTSPVHSSTSFPATSSPGDSTSTAVTSGTSSSATSPPEDSSSTAVTSGTSSPATSPPGDSSSTAVTSGTSSPATSPILDSSSTAVLSGTSSPATSPPEDSTSTAVTSGTSSPATSPPEDSTSTAVTSGTSSPATSPILDSSSTAIHSGTSSPATSPPGDSSSTAVLSGASTQTTKAVSDLASTPTHNGIMVPTTWSALSSATSPVYSGSSATTNSSESDMATTPVYSGTPFSSTTATSAITPDHNGSLVRTTSSVLGLATSPAHDTSAVATTPVRNDTQSSVPSQQPISPTIPAISSHSTVSSSSYYSTAVFPTFSSNSSPQLSVGVSFFSLSFYIRNHPFNSSLEDPSSRYYQELKRNISGLFLQVFNGDFLGVSTIKFRSGSVVVASTVIFREGTFSASEVKSQLVQHKKEAADYNLTISEVNVNEMQFPSSAQSWPGVPGWGIALLVLVCILVALVIVYLIALALCQCRRKSYGQLDLFPTRDTYHPMSEYPTYHTHGRYVPPATTKRSPYEEVSTGNGSSGLSYTNPAVATTSANL

Target ORF information:

RefSeq Version	NM_012602.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mucin 1, cell surface associated (Muc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012602.1

ORF Insert Sequence:

ATGACCCCGG GCATACGGGT TCCTCTCCTC CTGCTGCTAC TTCTAGCAAG CCTAAAAGTC 
CGCAGTGGTG CCTCCTCCTC AACCACCAGC CTTCCAGGGG ACTCCTTCAG CACTGCAGTC 
CCCAGTGGTG CCTCTTCCTC AGCCACCAGC CCTCCAGTGG ACTCCACCAC CTCTCCAGTT 
CATAGTAGCA CCTCGTTCCC AGCCACCAGC CCTCCAGGAG ACTCCACCAG CACTGCAGTC 
CTCAGTGGTG ACTCAGATCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
CCCAATGGTG CCTCTTCCTC AGCCACCAGC CCTCCAGTGG ACTCCACCAC CTCCCCAGTT 
CATAGTAGCA CCTCGTTCCC AGCCACCAGC TCTCCAGGGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCTTCCTC AGCCACCAGC CCTCCAGAGG ACTCCTCCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTATATTGG ACTCCTCCAG CACTGCAGTC 
CTCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGAGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGAGG ACTCCACCAG CACTGCAGTC 
ACCAGTGGCA CCTCGTCCCC AGCCACCAGC CCTATATTGG ACTCCTCCAG CACTGCAATC 
CACAGTGGCA CCTCGTCCCC AGCCACCAGC CCTCCAGGGG ACTCCTCCAG CACTGCAGTC 
CTCAGCGGTG CTTCCACCCA AACCACCAAG GCTGTATCAG ACTTAGCTAG CACTCCAACC 
CACAATGGCA TCATGGTCCC AACTACCTGG TCTGCATTGA GCTCAGCCAC CAGTCCGGTG 
TACAGTGGTT CCTCAGCTAC AACTAATAGC TCTGAATCAG ACATGGCCAC CACTCCAGTG 
TACAGTGGCA CCCCATTCTC TTCTACCACG GCTACGTCAG CTATCACCCC AGACCACAAT 
GGCTCCTTGG TGCGAACTAC CAGTTCTGTG TTGGGCTTAG CCACCAGTCC AGCCCATGAT 
ACCTCTGCGG TGGCCACAAC TCCAGTCCGC AATGACACTC AGTCTTCAGT TCCAAGTCAG 
CAGCCCATCT CTCCCACCAT CCCCGCCATC TCCAGCCACA GTACTGTTAG CAGCAGCTCT 
TACTACAGCA CAGCGGTCTT CCCTACCTTC TCCAGTAACA GCTCACCCCA GTTGTCTGTC 
GGGGTCTCCT TCTTCTCGTT GTCTTTTTAC ATTCGGAACC ACCCATTTAA TTCTTCCCTG 
GAAGACCCCA GCTCCCGCTA CTACCAAGAA CTGAAGAGGA ACATTTCCGG ATTGTTTCTG 
CAGGTTTTTA ACGGAGACTT TCTGGGGGTC TCTACTATCA AGTTCAGGTC AGGCTCGGTG 
GTGGTAGCAT CGACTGTGAT TTTCCGGGAG GGCACTTTCA GTGCCTCTGA AGTGAAGTCA 
CAGCTCGTAC AACATAAGAA GGAGGCAGCT GACTATAATC TGACTATCTC GGAAGTCAAT 
GTGAATGAGA TGCAGTTCCC TTCCTCTGCC CAGTCTTGGC CTGGGGTACC AGGTTGGGGC 
ATTGCCCTGC TGGTACTGGT CTGTATTTTG GTGGCTTTGG TCATCGTCTA TCTCATTGCC 
CTGGCATTGT GCCAGTGCCG CAGAAAGAGC TATGGGCAGC TGGACCTCTT TCCAACCCGG 
GACACCTACC ATCCTATGAG TGAATATCCT ACCTACCACA CTCACGGACG CTATGTGCCC 
CCTGCCACTA CCAAACGTAG CCCCTATGAA GAGGTTTCGA CAGGCAATGG CAGTAGCGGT 
CTCTCTTACA CCAACCCGGC TGTGGCAACC ACTTCGGCCA ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Changes in pulmonary tissue structure and KL-6/MUC1 expression in a newborn rat model of hyperoxia-induced bronchopulmonary dysplasia.
Experimental lung research39(10)417-26(2013 Dec)
Zhu Y,Fu J,You K,Jin L,Wang M,Lu D,Xue X

Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model.
International journal of cancer132(8)1860-7(2013 Apr)
Ghosh SK,Uchida M,Yoo B,Ross AW,Gendler SJ,Gong J,Moore A,Medarova Z

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.
Nature genetics45(3)299-303(2013 Mar)
Kirby A,Gnirke A,Jaffe DB,Bare?ov? V,Pochet N,Blumenstiel B,Ye C,Aird D,Stevens C,Robinson JT,Cabili MN,Gat-Viks I,Kelliher E,Daza R,DeFelice M,H?lkov? H,Sovov? J,Vylet'al P,Antignac C,Guttman M,Handsaker RE,Perrin D,Steelman S,Sigurdsson S,Scheinman SJ,Sougnez C,Cibulskis K,Parkin M,Green T,Rossin E,Zody MC,Xavier RJ,Pollak MR,Alper SL,Lindblad-Toh K,Gabriel S,Hart PS,Regev A,Nusbaum C,Kmoch S,Bleyer AJ,Lander ES,Daly MJ

Novel biomarkers of arterial and venous ischemia in microvascular flaps.
PloS one8(8)e71628(2013)
Nguyen GK,Hwang BH,Zhang Y,Monahan JF,Davis GB,Lee YS,Ragina NP,Wang C,Zhou ZY,Hong YK,Spivak RM,Wong AK

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Muc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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