Mog cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mog
Entrez Gene ID	24558
Full Name	myelin oligodendrocyte glycoprotein
General protein information	Preferred Names myelin oligodendrocyte glycoprotein Names myelin-oligodendrocyte glycoprotein dystonia 2, torsion (autosomal recessive)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	a component of compact myelin of the CNS; may be involved in myelin stability [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601538.1	XP_017457027.1	myelin-oligodendrocyte glycoprotein isoform X1
XM_008772687.2	XP_008770909.1	myelin-oligodendrocyte glycoprotein isoform X1
XM_017601540.1	XP_017457029.1	myelin-oligodendrocyte glycoprotein isoform X2
XM_006255867.3	XP_006255929.1	myelin-oligodendrocyte glycoprotein isoform X3
NM_022668.2	NP_073159.2	myelin-oligodendrocyte glycoprotein precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MOG	NP_001013602.1
Gallus gallus (chicken)	LOC101750077	XP_004945727.1
Gallus gallus (chicken)	LOC100858529	XP_003642284.2
Gallus gallus (chicken)	LOC768349	XP_003642289.2
Pan troglodytes (chimpanzee)	MOG	XP_001146331.1
Gallus gallus (chicken)	MOG	XP_004939786.1
Gallus gallus (chicken)	LOC101748132	XP_004945722.1
Gallus gallus (chicken)	LOC425214	XP_003642285.2
Gallus gallus (chicken)	BG2	XP_004945728.1
Gallus gallus (chicken)	LOC427725	XP_425300.4
Gallus gallus (chicken)	B-G	NP_001025841.1
Gallus gallus (chicken)	LOC100858813	XP_003642288.2
	MOG	XP_001103608.1
Rattus norvegicus (Norway rat)	Mog	NP_073159.2
Homo sapiens (human)	MOG	NP_996532.2
Canis lupus familiaris (dog)	MOG	XP_005640200.1
Mus musculus (house mouse)	Mog	NP_034944.2
Gallus gallus (chicken)	LOC101747935	XP_004945721.1
Gallus gallus (chicken)	LOC100859562	XP_004950002.1
Gallus gallus (chicken)	LOC100859531	XP_003643264.2
Gallus gallus (chicken)	LOC768351	XP_001231197.3

Gene Ontology
Bibliography

Related articles in PubMed

A combined NMR and molecular dynamics simulation study to determine the conformational properties of rat/mouse 35-55 myelin oligodendrocyte glycoprotein epitope implicated in the induction of experimental autoimmune encephalomyelitis.
Ntountaniotis D, Vanioti ?, Kordopati GG, Kellici TF, Marousis KD, Mavromoustakos T, Spyroulias GA, Golic Grdadolnik S, Tselios TV
Journal of biomolecular structure & dynamics35(7)1559-1567(2017 05)

The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry.
von B?dingen HC, Mei F, Greenfield A, Jahn S, Shen YA, Reid HH, McKemy DD, Chan JR
The Journal of cell biology210(6)891-8(2015 Sep)

MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE.
Mony JT, Khorooshi R, Owens T
Multiple sclerosis (Houndmills, Basingstoke, England)20(10)1312-21(2014 Sep)

Early postnatal repeated maternal deprivation causes a transient increase in OMpg and BDNF in rat cerebellum suggesting precocious myelination.
Miki T, Yokoyama T, Kusaka T, Suzuki S, Ohta K, Warita K, Wang ZY, Ueki M, Sumitani K, Bellinger FP, Tamai M, Liu JQ, Yakura T, Takeuchi Y
Journal of the neurological sciences336(1-2)62-7(2014 Jan)

Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS.
Xie F, Zhang JC, Fu H, Chen J
International journal of molecular medicine32(5)1021-8(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Identify nerve growth factor as a binding partner for MOG and demonstrate that this interaction is capable of sequestering NGF from TrkA-expressing neurons to modulate axon growth and survival.
Title: The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry.

MOG(1-125) immunization resulted in an increased incidence of severe experimental autoimmune encephalomyelitis and was accompanied by an increased percentage of CXCR3-expressing CD4+ T cells producing IFNgamma in the CNS.
Title: MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE.

Mog levels are significantly increased in cerebellum following maternal deprivation.
Title: Early postnatal repeated maternal deprivation causes a transient increase in OMpg and BDNF in rat cerebellum suggesting precocious myelination.

OMgp was only expressed in the inner plexiform layer of rats with experimental ocular hypertension.
Title: The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension: the expression of myelin proteins in the retina in glaucoma.

Mechanistic studies reveal that myelin oligodendrocyte glycoprotein (Mog) suppresses long-term potentiation in a Nogo receptor-1 (NgR1)-dependent manner.
Title: Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.

The following Mog gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mog cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06214	NM_022668.2 Latest version!	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa39087	XM_006255867.3 Latest version!	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa42922	XM_008772687.2 Latest version!	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa42922	XM_017601538.1 Latest version!	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa60035	XM_017601540.1 Latest version!	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mog ( NM_022668.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073159.2 Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), mRNA.

Price & Availability↑

CloneID	ORa06214
Clone ID Related Accession (Same CDS sequence)	NM_022668.2
Accession Version	NM_022668.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	myelin-oligodendrocyte glycoprotein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC087717.1. On Oct 13, 2007 this sequence version replaced NM_022668.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087717.1, FQ214199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMN02642596 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGACAGTT TCTTGAAGAG 
CTAAGAAACC CCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073159.2
CDS	89..826
Translation	MAGVWSLSLPSCLLSLLLLLQLSCSYAGQFRVIGPGHPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGQFLEELRNPF

Target ORF information:

RefSeq Version	NM_022668.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022668.2

ORF Insert Sequence:

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGACAGTT TCTTGAAGAG 
CTAAGAAACC CCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mog ( XM_006255867.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255929.1 Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa39087
Clone ID Related Accession (Same CDS sequence)	XM_006255867.3
Accession Version	XM_006255867.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin-oligodendrocyte glycoprotein isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255867.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGACAGTT TCTTGAAGAG 
CTAAGTAAGT TCTCCCTAAC GCCCCTCTCC ATTCTTGAGA CATCTCATTA CGCAGCCCTA 
GAACTCACTA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255929.1
CDS	203..997
Translation	MAGVWSLSLPSCLLSLLLLLQLSCSYAGQFRVIGPGHPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGQFLEELSKFSLTPLSILETSHYAALELTM

Target ORF information:

RefSeq Version	XM_006255867.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255867.3

ORF Insert Sequence:

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGACAGTT TCTTGAAGAG 
CTAAGTAAGT TCTCCCTAAC GCCCCTCTCC ATTCTTGAGA CATCTCATTA CGCAGCCCTA 
GAACTCACTA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mog ( XM_017601538.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457027.1 Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42922
Clone ID Related Accession (Same CDS sequence)	XM_017601538.1 , XM_008772687.2
Accession Version	XM_017601538.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 996bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin-oligodendrocyte glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGTGCAAT GTCTGGGCAG 
CAAACAGGAC CACTGTGGGG CGGGGGGGGG GGGAGGGGGG GGAGCTCAGG CAGACCAGAA 
CGGGAAAAGA GTGGAACCAA GGTTCTAGAT CCCAGGGCTG AGAATCTTTT TGCTCTCTCT 
ACTCTCACCA TCAGAATCCT CAGGAAAACT GAGGACCACT TACTGAGATG CACAGGCCCC 
TTAATGGAAA AGAAGGGTTG TCTGAGGAGG TGGGGGGGAG GCTCCCACTG GTCACCCATC 
GACTCATTTC TCTTTGTTTA CAGGACAGTT TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457027.1
CDS	211..1206
Translation	MAGVWSLSLPSCLLSLLLLLQLSCSYAGQFRVIGPGHPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGAMSGQQTGPLWGGGGGRGGSSGRPEREKSGTKVLDPRAENLFALSTLTIRILRKTEDHLLRCTGPLMEKKGCLRRWGGGSHWSPIDSFLFVYRTVS

Target ORF information:

RefSeq Version	XM_017601538.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601538.1

ORF Insert Sequence:

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGTGCAAT GTCTGGGCAG 
CAAACAGGAC CACTGTGGGG CGGGGGGGGG GGGAGGGGGG GGAGCTCAGG CAGACCAGAA 
CGGGAAAAGA GTGGAACCAA GGTTCTAGAT CCCAGGGCTG AGAATCTTTT TGCTCTCTCT 
ACTCTCACCA TCAGAATCCT CAGGAAAACT GAGGACCACT TACTGAGATG CACAGGCCCC 
TTAATGGAAA AGAAGGGTTG TCTGAGGAGG TGGGGGGGAG GCTCCCACTG GTCACCCATC 
GACTCATTTC TCTTTGTTTA CAGGACAGTT TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mog ( XM_008772687.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008770909.1 Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa42922
Clone ID Related Accession (Same CDS sequence)	XM_017601538.1 , XM_008772687.2
Accession Version	XM_008772687.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 996bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin-oligodendrocyte glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772687.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGTGCAAT GTCTGGGCAG 
CAAACAGGAC CACTGTGGGG CGGGGGGGGG GGGAGGGGGG GGAGCTCAGG CAGACCAGAA 
CGGGAAAAGA GTGGAACCAA GGTTCTAGAT CCCAGGGCTG AGAATCTTTT TGCTCTCTCT 
ACTCTCACCA TCAGAATCCT CAGGAAAACT GAGGACCACT TACTGAGATG CACAGGCCCC 
TTAATGGAAA AGAAGGGTTG TCTGAGGAGG TGGGGGGGAG GCTCCCACTG GTCACCCATC 
GACTCATTTC TCTTTGTTTA CAGGACAGTT TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008770909.1
CDS	270..1265
Translation	MAGVWSLSLPSCLLSLLLLLQLSCSYAGQFRVIGPGHPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGAMSGQQTGPLWGGGGGRGGSSGRPEREKSGTKVLDPRAENLFALSTLTIRILRKTEDHLLRCTGPLMEKKGCLRRWGGGSHWSPIDSFLFVYRTVS

Target ORF information:

RefSeq Version	XM_008772687.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008772687.2

ORF Insert Sequence:

ATGGCCGGTG TGTGGAGCCT TTCTCTGCCC AGCTGCCTCC TGTCCCTGCT CCTCCTCCTC 
CAGTTGTCAT GCAGCTACGC AGGACAGTTC AGAGTGATAG GGCCAGGGCA TCCCATCCGG 
GCTTTAGTTG GGGATGAAGC AGAACTGCCG TGCCGTATAT CTCCTGGGAA GAATGCCACG 
GGCATGGAGG TGGGGTGGTA CCGTTCTCCC TTTTCAAGAG TGGTTCATCT GTACCGAAAT 
GGCAAGGACC AAGACGCAGA GCAAGCGCCT GAATACCGGG GACGCACAGA GCTTCTGAAA 
GAGTCTATCG GCGAGGGAAA GGTTGCCCTC AGGATCCAGA ACGTGAGGTT CTCGGATGAA 
GGAGGCTACA CATGCTTCTT CAGAGACCAC TCCTACCAAG AAGAAGCCGC CGTGGAGTTG 
AAAGTAGAAG ATCCCTTCTA CTGGATCAAC CCTGGCGTGC TGGCTCTCAT TGCCCTTGTG 
CCTATGCTGC TCCTGCAGGT CTCTGTAGGC CTTGTATTCC TCTTCCTGCA GCACAGACTG 
AGAGGAAAAC TCCGTGCAGA AGTCGAGAAT CTCCATCGGA CTTTTGATCC TCACTTCCTG 
AGAGTGCCCT GCTGGAAGAT AACACTGTTT GTTATTGTCC CTGTTCTTGG ACCCCTGGTT 
GCTTTGATCA TCTGCTACAA CTGGCTGCAC CGAAGACTGG CAGGTGCAAT GTCTGGGCAG 
CAAACAGGAC CACTGTGGGG CGGGGGGGGG GGGAGGGGGG GGAGCTCAGG CAGACCAGAA 
CGGGAAAAGA GTGGAACCAA GGTTCTAGAT CCCAGGGCTG AGAATCTTTT TGCTCTCTCT 
ACTCTCACCA TCAGAATCCT CAGGAAAACT GAGGACCACT TACTGAGATG CACAGGCCCC 
TTAATGGAAA AGAAGGGTTG TCTGAGGAGG TGGGGGGGAG GCTCCCACTG GTCACCCATC 
GACTCATTTC TCTTTGTTTA CAGGACAGTT TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mog ( XM_017601540.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457029.1 Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X3, mRNA.

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CloneID	ORa60035
Clone ID Related Accession (Same CDS sequence)	XM_017601540.1
Accession Version	XM_017601540.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin-oligodendrocyte glycoprotein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGTGG GGTGGTACCG TTCTCCCTTT TCAAGAGTGG TTCATCTGTA CCGAAATGGC 
AAGGACCAAG ACGCAGAGCA AGCGCCTGAA TACCGGGGAC GCACAGAGCT TCTGAAAGAG 
TCTATCGGCG AGGGAAAGGT TGCCCTCAGG ATCCAGAACG TGAGGTTCTC GGATGAAGGA 
GGCTACACAT GCTTCTTCAG AGACCACTCC TACCAAGAAG AAGCCGCCGT GGAGTTGAAA 
GTAGAAGATC CCTTCTACTG GATCAACCCT GGCGTGCTGG CTCTCATTGC CCTTGTGCCT 
ATGCTGCTCC TGCAGGTCTC TGTAGGCCTT GTATTCCTCT TCCTGCAGCA CAGACTGAGA 
GGAAAACTCC GTGCAGAAGT CGAGAATCTC CATCGGACTT TTGATCCTCA CTTCCTGAGA 
GTGCCCTGCT GGAAGATAAC ACTGTTTGTT ATTGTCCCTG TTCTTGGACC CCTGGTTGCT 
TTGATCATCT GCTACAACTG GCTGCACCGA AGACTGGCAG GTGCAATGTC TGGGCAGCAA 
ACAGGACCAC TGTGGGGCGG GGGGGGGGGG AGGGGGGGGA GCTCAGGCAG ACCAGAACGG 
GAAAAGAGTG GAACCAAGGT TCTAGATCCC AGGGCTGAGA ATCTTTTTGC TCTCTCTACT 
CTCACCATCA GAATCCTCAG GAAAACTGAG GACCACTTAC TGAGATGCAC AGGCCCCTTA 
ATGGAAAAGA AGGGTTGTCT GAGGAGGTGG GGGGGAGGCT CCCACTGGTC ACCCATCGAC 
TCATTTCTCT TTGTTTACAG GACAGTTTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457029.1
CDS	1446..2258
Translation	MEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGAMSGQQTGPLWGGGGGRGGSSGRPEREKSGTKVLDPRAENLFALSTLTIRILRKTEDHLLRCTGPLMEKKGCLRRWGGGSHWSPIDSFLFVYRTVS

Target ORF information:

RefSeq Version	XM_017601540.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myelin oligodendrocyte glycoprotein (Mog), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601540.1

ORF Insert Sequence:

ATGGAGGTGG GGTGGTACCG TTCTCCCTTT TCAAGAGTGG TTCATCTGTA CCGAAATGGC 
AAGGACCAAG ACGCAGAGCA AGCGCCTGAA TACCGGGGAC GCACAGAGCT TCTGAAAGAG 
TCTATCGGCG AGGGAAAGGT TGCCCTCAGG ATCCAGAACG TGAGGTTCTC GGATGAAGGA 
GGCTACACAT GCTTCTTCAG AGACCACTCC TACCAAGAAG AAGCCGCCGT GGAGTTGAAA 
GTAGAAGATC CCTTCTACTG GATCAACCCT GGCGTGCTGG CTCTCATTGC CCTTGTGCCT 
ATGCTGCTCC TGCAGGTCTC TGTAGGCCTT GTATTCCTCT TCCTGCAGCA CAGACTGAGA 
GGAAAACTCC GTGCAGAAGT CGAGAATCTC CATCGGACTT TTGATCCTCA CTTCCTGAGA 
GTGCCCTGCT GGAAGATAAC ACTGTTTGTT ATTGTCCCTG TTCTTGGACC CCTGGTTGCT 
TTGATCATCT GCTACAACTG GCTGCACCGA AGACTGGCAG GTGCAATGTC TGGGCAGCAA 
ACAGGACCAC TGTGGGGCGG GGGGGGGGGG AGGGGGGGGA GCTCAGGCAG ACCAGAACGG 
GAAAAGAGTG GAACCAAGGT TCTAGATCCC AGGGCTGAGA ATCTTTTTGC TCTCTCTACT 
CTCACCATCA GAATCCTCAG GAAAACTGAG GACCACTTAC TGAGATGCAC AGGCCCCTTA 
ATGGAAAAGA AGGGTTGTCT GAGGAGGTGG GGGGGAGGCT CCCACTGGTC ACCCATCGAC 
TCATTTCTCT TTGTTTACAG GACAGTTTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A combined NMR and molecular dynamics simulation study to determine the conformational properties of rat/mouse 35-55 myelin oligodendrocyte glycoprotein epitope implicated in the induction of experimental autoimmune encephalomyelitis.
Journal of biomolecular structure & dynamics35(7)1559-1567(2017 05)
Ntountaniotis D,Vanioti ?,Kordopati GG,Kellici TF,Marousis KD,Mavromoustakos T,Spyroulias GA,Golic Grdadolnik S,Tselios TV

The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry.
The Journal of cell biology210(6)891-8(2015 Sep)
von B?dingen HC,Mei F,Greenfield A,Jahn S,Shen YA,Reid HH,McKemy DD,Chan JR

MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE.
Multiple sclerosis (Houndmills, Basingstoke, England)20(10)1312-21(2014 Sep)
Mony JT,Khorooshi R,Owens T

Early postnatal repeated maternal deprivation causes a transient increase in OMpg and BDNF in rat cerebellum suggesting precocious myelination.
Journal of the neurological sciences336(1-2)62-7(2014 Jan)
Miki T,Yokoyama T,Kusaka T,Suzuki S,Ohta K,Warita K,Wang ZY,Ueki M,Sumitani K,Bellinger FP,Tamai M,Liu JQ,Yakura T,Takeuchi Y

Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS.
International journal of molecular medicine32(5)1021-8(2013 Nov)
Xie F,Zhang JC,Fu H,Chen J

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Mog cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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