Atp2b2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atp2b2
Entrez Gene ID	24215
Full Name	ATPase plasma membrane Ca2+ transporting 2
Synonyms	PMCA2
General protein information	Preferred Names ATPase plasma membrane Ca2+ transporting 2 Names plasma membrane calcium-transporting ATPase 2 ATPase isoform 2, Na+K+ transporting, beta polypeptide 2 ATPase, Ca++ transporting, plasma membrane 2 plasma membrane Ca++-ATPase plasma membrane calcium ATPase plasma membrane calcium pump
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42
Summary	regulates intracellular calcium ion levels [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012508.5	NP_036640.1	plasma membrane calcium-transporting ATPase 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ATP2B2	NP_001001331.1
Gallus gallus (chicken)	ATP2B2	XP_001231642.1
Danio rerio (zebrafish)	atp2b2	NP_001116710.1
Kluyveromyces lactis	KLLA0A08910g	XP_451391.1
Xenopus tropicalis (tropical clawed frog)	atp2b2	XP_002934276.2
Mus musculus (house mouse)	Atp2b2	NP_033853.1
Eremothecium gossypii	AGOS_AFL011W	NP_985537.1
Oryza sativa (rice)	Os02g0176700	NP_001046064.2
Pan troglodytes (chimpanzee)	ATP2B2	XP_001151685.2
Canis lupus familiaris (dog)	ATP2B2	XP_005632215.1
Rattus norvegicus (Norway rat)	Atp2b2	NP_036640.1
Magnaporthe oryzae (rice blast fungus)	MGG_02487	XP_003709283.1
Neurospora crassa	NCU04736	XP_960371.2
Bos taurus (cattle)	ATP2B2	NP_001178174.1
Saccharomyces cerevisiae (baker's yeast)	PMC1	NP_011509.1

Gene Ontology
Bibliography

Related articles in PubMed

Cross talk among PMCA, calcineurin and NFAT transcription factors in control of calmodulin gene expression in differentiating PC12 cells.
Boczek T, Lisek M, Ferenc B, Zylinska L
Biochimica et biophysica acta1860(4)502-515(2017 04)

Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX).
de Juan-Sanz J, N??ez E, Zafra F, Berrocal M, Corbacho I, Ib??ez I, Arribas-Gonz?lez E, Marcos D, L?pez-Corcuera B, Mata AM, Arag?n C
The Journal of biological chemistry289(49)34308-24(2014 Dec)

Plasma membrane Ca2+-ATPase isoforms composition regulates cellular pH homeostasis in differentiating PC12 cells in a manner dependent on cytosolic Ca2+ elevations.
Boczek T, Lisek M, Ferenc B, Kowalski A, Stepinski D, Wiktorska M, Zylinska L
PloS one9(7)e102352(2014)

Silencing of plasma membrane Ca2+-ATPase isoforms 2 and 3 impairs energy metabolism in differentiating PC12 cells.
Boczek T, Lisek M, Ferenc B, Kowalski A, Wiktorska M, Zylinska L
BioMed research international2014735106(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

higher occupancy of Calm2 and Calm3 promoters by NFATc2 and increased expression of these genes in response to NFATc2 silencing were demonstrated in PMCA2 and PMCA3-reduced lines.
Title: Cross talk among PMCA, calcineurin and NFAT transcription factors in control of calmodulin gene expression in differentiating PC12 cells.

GlyT2 activity is pre-synaptically controlled by physical and functional association with plasma membrane PMCA2, PMCA3, and NCX1.
Title: Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX).

Plasma membrane PMCA2 and PMCA3 regulate cellular pH homeostasis in differentiating adrenal chromaffin cell line in a manner dependent on cytosolic Ca2+ elevations.
Title: Plasma membrane Ca2+-ATPase isoforms composition regulates cellular pH homeostasis in differentiating PC12 cells in a manner dependent on cytosolic Ca2+ elevations.

Results demonstrate a significant impairment of cell survival under conditions of PMCA2 suppression. Overexpression of PMCA2 rendered the neurons significantly resistant to complex I inhibition.
Title: Downregulation of PMCA2 increases the vulnerability of midbrain neurons to mitochondrial complex I inhibition.

The results with PMCA2- or PMCA3-downregulated lines provide an evidence of a novel role of PMCA isoforms in regulation of bioenergetic pathways.
Title: Silencing of plasma membrane Ca2+-ATPase isoforms 2 and 3 impairs energy metabolism in differentiating PC12 cells.

The following Atp2b2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atp2b2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00129	NM_012508.5 Latest version!	Rattus norvegicus ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atp2b2 ( NM_012508.5 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036640.1 Rattus norvegicus ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), mRNA.

Price & Availability↑

CloneID	ORa00129
Clone ID Related Accession (Same CDS sequence)	NM_012508.5
Accession Version	NM_012508.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	plasma membrane calcium-transporting ATPase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J03754.1. On Apr 19, 2007 this sequence version replaced NM_012508.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03754.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGTGATA TGACCAACAG CGACTTTTAC TCCAAAAACC AAAGAAATGA GTCGAGCCAT 
GGGGGCGAGT TCGGGTGCAG CATGGAGGAG CTGCGCTCCC TCATGGAGCT GCGGGGCACT 
GAGGCTGTGG TCAAGATCAA GGAGACATAT GGGGACACTG AATCCATCTG CCGGCGCCTC 
AAAACCTCTC CTGTTGAAGG TTTGCCAGGC ACCGCTCCAG ACCTGGAAAA GAGGAAACAG 
ATTTTCGGGC AAAACTTCAT ACCTCCAAAG AAACCAAAAA CCTTCCTGCA GCTGGTGTGG 
GAAGCACTAC AGGACGTGAC GCTCATCATC CTGGAGATCG CGGCCATCAT CTCCCTGGGA 
CTGTCCTTCT ACCACCCACC CGGAGAGAGC AATGAAGGAT GTGCCACGGC CCAAGGTGGG 
GCAGAAGATG AAGGTGAAGC AGAAGCAGGC TGGATCGAGG GGGCTGCCAT CCTGCTGTCA 
GTCATCTGTG TGGTCCTCGT CACAGCCTTC AATGATTGGA GTAAAGAGAA ACAGTTCCGG 
GGCCTGCAGA GCCGAATTGA GCAGGAACAG AAGTTCACCG TAGTCCGGGC TGGCCAGGTG 
GTCCAGATCC CTGTGGCCGA GATTGTGGTT GGGGACATTG CCCAGATCAA ATACGGTGAC 
CTCCTTCCTG CTGATGGCCT CTTCATCCAG GGCAATGACC TCAAGATCGA TGAAAGCTCG 
CTCACAGGGG AGTCTGACCA GGTGCGCAAG TCTGTGGATA AGGACCCTAT GTTGCTGTCA 
GGAACTCATG TGATGGAAGG CTCAGGACGG ATGGTGGTGA CTGCTGTGGG TGTCAACTCT 
CAAACTGGCA TCATATTTAC CCTGCTTGGG GCTGGTGGTG AAGAGGAAGA GAAGAAAGAC 
AAAAAAGCCA AGCAGCAGGA TGGGGCAGCT GCTATGGAAA TGCAGCCTCT GAAGAGTGCG 
GAGGGCGGTG ATGCAGATGA CAAGAAGAAA GCCAACATGC ACAAGAAAGA GAAGTCGGTG 
CTTCAGGGCA AGCTCACCAA GCTGGCTGTG CAGATAGGCA AGGCGGGCCT GGTGATGTCG 
GCCATCACGG TGATCATCCT GGTGCTCTAC TTCACCGTGG ACACCTTCGT GGTCAACAAG 
AAGCCGTGGC TGACGGAGTG CACACCGGTC TACGTGCAGT ACTTCGTCAA GTTCTTCATC 
ATTGGTGTGA CGGTGCTGGT GGTCGCTGTG CCCGAGGGCC TCCCTCTGGC TGTCACCATC 
TCACTGGCCT ATTCCGTGAA GAAAATGATG AAGGACAACA ACCTGGTCCG TCACCTGGAC 
GCCTGTGAGA CCATGGGTAA CGCCACAGCC ATCTGCTCAG ACAAGACAGG CACGCTGACC 
ACCAACCGCA TGACCGTGGT GCAGGCCTAT GTCGGTGATG TCCACTACAA GGAGATCCCT 
GATCCCAGCT CCATCAATGC CAAGACATTG GAGCTGCTGG TCAACGCCAT TGCCATCAAC 
AGCGCCTACA CCACCAAGAT CCTCCCCCCA GAAAAAGAGG GCGCCCTGCC CCGGCAGGTG 
GGCAACAAGA CAGAGTGTGG CCTGCTGGGC TTCGTGCTGG ACCTGAGGCA GGATTACGAG 
CCGGTACGCA GCCAGATGCC AGAGGAAAAG CTGTATAAGG TGTACACCTT CAACTCTGTG 
CGCAAGTCCA TGAGCACCGT CATCAAGATG CCTGACGAGA GCTTCCGCAT GTACAGCAAA 
GGTGCTTCGG AGATTGTGCT CAAAAAGTGC TGCAAGATTC TCAGTGGGGC AGGGGAGCCC 
CGTGTCTTCC GGCCCCGTGA CAGGGATGAG ATGGTTAAGA AGGTGATCGA GCCCATGGCC 
TGTGACGGGC TCCGTACCAT CTGTGTGGCC TATCGTGACT TCCCCAGCAG CCCTGAGCCT 
GACTGGGACA ATGAGAATGA CATTCTCAAT GAACTCACCT GCATCTGCGT GGTGGGCATC 
GAAGACCCAG TGCGACCTGA GGTCCCAGAA GCCATCCGCA AGTGCCAGCG GGCCGGTATC 
ACAGTCCGCA TGGTCACCGG TGACAACATC AACACAGCCC GGGCCATCGC CATCAAGTGT 
GGCATTATCC ACCCTGGAGA GGACTTCCTG TGCCTGGAAG GCAAAGAATT CAATCGGAGG 
ATCCGCAACG AGAAGGGGGA GATTGAGCAG GAGCGGATTG ACAAGATCTG GCCAAAGCTG 
AGGGTGCTGG CTCGATCCTC GCCCACGGAT AAGCACACCC TGGTCAAAGG CATCATCGAC 
AGCACACACA CTGAGCAGCG GCAGGTGGTG GCTGTGACAG GGGATGGGAC CAACGATGGG 
CCTGCTCTCA AGAAGGCAGA TGTGGGCTTC GCGATGGGCA TCGCAGGCAC GGATGTGGCC 
AAGGAGGCCT CAGACATCAT CCTGACAGAC GACAACTTCA GCAGCATCGT TAAGGCAGTG 
ATGTGGGGCC GTAATGTCTA TGACAGCATA TCCAAATTCC TGCAGTTTCA GCTGACTGTC 
AATGTGGTGG CTGTGATCGT GGCCTTCACG GGTGCCTGCA TTACACAGGA CTCCCCTCTC 
AAGGCGGTGC AGATGCTCTG GGTGAACCTC ATCATGGACA CATTTGCTTC CCTGGCCCTG 
GCAACAGAGC CACCCACCGA GACTCTGCTC CTGAGGAAAC CTTACGGCCG CAACAAGCCG 
CTCATCTCGA GAACCATGAT GAAGAACATC CTGGGCCACG CCGTCTACCA GCTAACCCTC 
ATCTTCACCC TGCTCTTCGT GGGTGAGAAG ATGTTCCAGA TTGACAGCGG AAGGAACGCC 
CCGCTGCACT CGCCACCCTC GGAGCACTAC ACCATCATCT TCAACACCTT CGTCATGATG 
CAGCTTTTCA ACGAGATCAA CGCCCGTAAG ATCCACGGCG AGCGTAACGT CTTCGACGGA 
ATCTTCCGGA ACCCCATCTT CTGCACCATC GTTCTCGGCA CTTTTGCCAT CCAGATAGTG 
ATTGTGCAGT TCGGCGGCAA ACCCTTCAGC TGCTCCCCAC TCCAGCTGGA CCAGTGGATG 
TGGTGCATCT TCATAGGCCT GGGAGAGCTC GTCTGGGGCC AGGTCATTGC CACCATCCCT 
ACCAGCAGGC TCAAGTTTCT GAAAGAGGCA GGGCGGCTAA CACAGAAGGA GGAGATCCCC 
GAGGAAGAGT TAAATGAGGA TGTGGAAGAG ATAGACCACG CAGAGCGGGA GCTTCGCCGA 
GGCCAGATCC TATGGTTCCG GGGCCTGAAT CGGATCCAGA CACAGATCCG CGTCGTGAAG 
GCGTTCCGTA GCTCTCTCTA TGAAGGGTTA GAAAAACCCG AGTCTCGAAC CTCCATCCAT 
AACTTCATGG CTCATCCTGA ATTCCGGATC GAAGATTCCC AGCCCCACAT CCCCCTCATC 
GATGACACCG ACCTGGAAGA AGATGCCGCG CTCAAGCAGA ACTCGAGCCC GCCGTCCTCG 
CTCAACAAGA ACAATAGCGC CATCGACAGC GGGATCAACC TGACGACCGA CACGAGCAAA 
TCAGCTACCT CTTCAAGTCC AGGGAGCCCC ATCCACAGCC TGGAGACGTC GCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036640.1
CDS	547..4143
Translation	MGDMTNSDFYSKNQRNESSHGGEFGCSMEELRSLMELRGTEAVVKIKETYGDTESICRRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGESNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQIKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDKKKANMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLTECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINAKTLELLVNAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLRQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKMPDESFRMYSKGASEIVLKKCCKILSGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLTLIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL

Target ORF information:

RefSeq Version	NM_012508.5
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012508.5

ORF Insert Sequence:

ATGGGTGATA TGACCAACAG CGACTTTTAC TCCAAAAACC AAAGAAATGA GTCGAGCCAT 
GGGGGCGAGT TCGGGTGCAG CATGGAGGAG CTGCGCTCCC TCATGGAGCT GCGGGGCACT 
GAGGCTGTGG TCAAGATCAA GGAGACATAT GGGGACACTG AATCCATCTG CCGGCGCCTC 
AAAACCTCTC CTGTTGAAGG TTTGCCAGGC ACCGCTCCAG ACCTGGAAAA GAGGAAACAG 
ATTTTCGGGC AAAACTTCAT ACCTCCAAAG AAACCAAAAA CCTTCCTGCA GCTGGTGTGG 
GAAGCACTAC AGGACGTGAC GCTCATCATC CTGGAGATCG CGGCCATCAT CTCCCTGGGA 
CTGTCCTTCT ACCACCCACC CGGAGAGAGC AATGAAGGAT GTGCCACGGC CCAAGGTGGG 
GCAGAAGATG AAGGTGAAGC AGAAGCAGGC TGGATCGAGG GGGCTGCCAT CCTGCTGTCA 
GTCATCTGTG TGGTCCTCGT CACAGCCTTC AATGATTGGA GTAAAGAGAA ACAGTTCCGG 
GGCCTGCAGA GCCGAATTGA GCAGGAACAG AAGTTCACCG TAGTCCGGGC TGGCCAGGTG 
GTCCAGATCC CTGTGGCCGA GATTGTGGTT GGGGACATTG CCCAGATCAA ATACGGTGAC 
CTCCTTCCTG CTGATGGCCT CTTCATCCAG GGCAATGACC TCAAGATCGA TGAAAGCTCG 
CTCACAGGGG AGTCTGACCA GGTGCGCAAG TCTGTGGATA AGGACCCTAT GTTGCTGTCA 
GGAACTCATG TGATGGAAGG CTCAGGACGG ATGGTGGTGA CTGCTGTGGG TGTCAACTCT 
CAAACTGGCA TCATATTTAC CCTGCTTGGG GCTGGTGGTG AAGAGGAAGA GAAGAAAGAC 
AAAAAAGCCA AGCAGCAGGA TGGGGCAGCT GCTATGGAAA TGCAGCCTCT GAAGAGTGCG 
GAGGGCGGTG ATGCAGATGA CAAGAAGAAA GCCAACATGC ACAAGAAAGA GAAGTCGGTG 
CTTCAGGGCA AGCTCACCAA GCTGGCTGTG CAGATAGGCA AGGCGGGCCT GGTGATGTCG 
GCCATCACGG TGATCATCCT GGTGCTCTAC TTCACCGTGG ACACCTTCGT GGTCAACAAG 
AAGCCGTGGC TGACGGAGTG CACACCGGTC TACGTGCAGT ACTTCGTCAA GTTCTTCATC 
ATTGGTGTGA CGGTGCTGGT GGTCGCTGTG CCCGAGGGCC TCCCTCTGGC TGTCACCATC 
TCACTGGCCT ATTCCGTGAA GAAAATGATG AAGGACAACA ACCTGGTCCG TCACCTGGAC 
GCCTGTGAGA CCATGGGTAA CGCCACAGCC ATCTGCTCAG ACAAGACAGG CACGCTGACC 
ACCAACCGCA TGACCGTGGT GCAGGCCTAT GTCGGTGATG TCCACTACAA GGAGATCCCT 
GATCCCAGCT CCATCAATGC CAAGACATTG GAGCTGCTGG TCAACGCCAT TGCCATCAAC 
AGCGCCTACA CCACCAAGAT CCTCCCCCCA GAAAAAGAGG GCGCCCTGCC CCGGCAGGTG 
GGCAACAAGA CAGAGTGTGG CCTGCTGGGC TTCGTGCTGG ACCTGAGGCA GGATTACGAG 
CCGGTACGCA GCCAGATGCC AGAGGAAAAG CTGTATAAGG TGTACACCTT CAACTCTGTG 
CGCAAGTCCA TGAGCACCGT CATCAAGATG CCTGACGAGA GCTTCCGCAT GTACAGCAAA 
GGTGCTTCGG AGATTGTGCT CAAAAAGTGC TGCAAGATTC TCAGTGGGGC AGGGGAGCCC 
CGTGTCTTCC GGCCCCGTGA CAGGGATGAG ATGGTTAAGA AGGTGATCGA GCCCATGGCC 
TGTGACGGGC TCCGTACCAT CTGTGTGGCC TATCGTGACT TCCCCAGCAG CCCTGAGCCT 
GACTGGGACA ATGAGAATGA CATTCTCAAT GAACTCACCT GCATCTGCGT GGTGGGCATC 
GAAGACCCAG TGCGACCTGA GGTCCCAGAA GCCATCCGCA AGTGCCAGCG GGCCGGTATC 
ACAGTCCGCA TGGTCACCGG TGACAACATC AACACAGCCC GGGCCATCGC CATCAAGTGT 
GGCATTATCC ACCCTGGAGA GGACTTCCTG TGCCTGGAAG GCAAAGAATT CAATCGGAGG 
ATCCGCAACG AGAAGGGGGA GATTGAGCAG GAGCGGATTG ACAAGATCTG GCCAAAGCTG 
AGGGTGCTGG CTCGATCCTC GCCCACGGAT AAGCACACCC TGGTCAAAGG CATCATCGAC 
AGCACACACA CTGAGCAGCG GCAGGTGGTG GCTGTGACAG GGGATGGGAC CAACGATGGG 
CCTGCTCTCA AGAAGGCAGA TGTGGGCTTC GCGATGGGCA TCGCAGGCAC GGATGTGGCC 
AAGGAGGCCT CAGACATCAT CCTGACAGAC GACAACTTCA GCAGCATCGT TAAGGCAGTG 
ATGTGGGGCC GTAATGTCTA TGACAGCATA TCCAAATTCC TGCAGTTTCA GCTGACTGTC 
AATGTGGTGG CTGTGATCGT GGCCTTCACG GGTGCCTGCA TTACACAGGA CTCCCCTCTC 
AAGGCGGTGC AGATGCTCTG GGTGAACCTC ATCATGGACA CATTTGCTTC CCTGGCCCTG 
GCAACAGAGC CACCCACCGA GACTCTGCTC CTGAGGAAAC CTTACGGCCG CAACAAGCCG 
CTCATCTCGA GAACCATGAT GAAGAACATC CTGGGCCACG CCGTCTACCA GCTAACCCTC 
ATCTTCACCC TGCTCTTCGT GGGTGAGAAG ATGTTCCAGA TTGACAGCGG AAGGAACGCC 
CCGCTGCACT CGCCACCCTC GGAGCACTAC ACCATCATCT TCAACACCTT CGTCATGATG 
CAGCTTTTCA ACGAGATCAA CGCCCGTAAG ATCCACGGCG AGCGTAACGT CTTCGACGGA 
ATCTTCCGGA ACCCCATCTT CTGCACCATC GTTCTCGGCA CTTTTGCCAT CCAGATAGTG 
ATTGTGCAGT TCGGCGGCAA ACCCTTCAGC TGCTCCCCAC TCCAGCTGGA CCAGTGGATG 
TGGTGCATCT TCATAGGCCT GGGAGAGCTC GTCTGGGGCC AGGTCATTGC CACCATCCCT 
ACCAGCAGGC TCAAGTTTCT GAAAGAGGCA GGGCGGCTAA CACAGAAGGA GGAGATCCCC 
GAGGAAGAGT TAAATGAGGA TGTGGAAGAG ATAGACCACG CAGAGCGGGA GCTTCGCCGA 
GGCCAGATCC TATGGTTCCG GGGCCTGAAT CGGATCCAGA CACAGATCCG CGTCGTGAAG 
GCGTTCCGTA GCTCTCTCTA TGAAGGGTTA GAAAAACCCG AGTCTCGAAC CTCCATCCAT 
AACTTCATGG CTCATCCTGA ATTCCGGATC GAAGATTCCC AGCCCCACAT CCCCCTCATC 
GATGACACCG ACCTGGAAGA AGATGCCGCG CTCAAGCAGA ACTCGAGCCC GCCGTCCTCG 
CTCAACAAGA ACAATAGCGC CATCGACAGC GGGATCAACC TGACGACCGA CACGAGCAAA 
TCAGCTACCT CTTCAAGTCC AGGGAGCCCC ATCCACAGCC TGGAGACGTC GCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cross talk among PMCA, calcineurin and NFAT transcription factors in control of calmodulin gene expression in differentiating PC12 cells.
Biochimica et biophysica acta1860(4)502-515(2017 04)
Boczek T,Lisek M,Ferenc B,Zylinska L

Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX).
The Journal of biological chemistry289(49)34308-24(2014 Dec)
de Juan-Sanz J,N??ez E,Zafra F,Berrocal M,Corbacho I,Ib??ez I,Arribas-Gonz?lez E,Marcos D,L?pez-Corcuera B,Mata AM,Arag?n C

Plasma membrane Ca2+-ATPase isoforms composition regulates cellular pH homeostasis in differentiating PC12 cells in a manner dependent on cytosolic Ca2+ elevations.
PloS one9(7)e102352(2014)
Boczek T,Lisek M,Ferenc B,Kowalski A,Stepinski D,Wiktorska M,Zylinska L

Silencing of plasma membrane Ca2+-ATPase isoforms 2 and 3 impairs energy metabolism in differentiating PC12 cells.
BioMed research international2014735106(2014)
Boczek T,Lisek M,Ferenc B,Kowalski A,Wiktorska M,Zylinska L

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Atp2b2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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