Opn4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Opn4
Entrez Gene ID	192223
Full Name	opsin 4
General protein information	Preferred Names opsin 4 Names melanopsin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16p15
Summary	visual pigment of phototransducing retinal ganglion cells involved in setting the circadian clock [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017599986.1	XP_017455475.1	melanopsin isoform X2
XM_017599985.1	XP_017455474.1	melanopsin isoform X1
NM_138860.1	NP_620215.1	melanopsin
XM_017599987.1	XP_017455476.1	melanopsin isoform X3
XM_017599988.1	XP_017455477.1	melanopsin isoform X4
XM_017599989.1	XP_017455478.1	melanopsin isoform X4

Pathways from BioSystems

Homologies

Homo sapiens (human)	OPN4	NP_001025186.1
Pan troglodytes (chimpanzee)	OPN4	XP_001135445.1
Rattus norvegicus (Norway rat)	Opn4	NP_620215.1
Gallus gallus (chicken)	OPN4	NP_001038118.1
Drosophila melanogaster (fruit fly)	ninaE	NP_524407.1
	OPN4	XP_001088248.2
Xenopus tropicalis (tropical clawed frog)	LOC100491785	XP_002937616.1
Canis lupus familiaris (dog)	OPN4	XP_005619497.1
Bos taurus (cattle)	OPN4	NP_001179328.1
Mus musculus (house mouse)	Opn4	NP_001122071.1
Drosophila melanogaster (fruit fly)	Rh2	NP_524398.1

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of melanopsin in the retina restores visual function in Royal College of Surgeons rats.
Liu M, Dai J, Liu W, Zhao C, Yin ZQ
Molecular medicine reports13(1)321-6(2016 Jan)

Isoforms of Melanopsin Mediate Different Behavioral Responses to Light.
Jagannath A, Hughes S, Abdelgany A, Pothecary CA, Di Pretoro S, Pires SS, Vachtsevanos A, Pilorz V, Brown LA, Hossbach M, MacLaren RE, Halford S, Gatti S, Hankins MW, Wood MJ, Foster RG, Peirson SN
Current biology : CB25(18)2430-4(2015 Sep)

Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats.
Nadal-Nicol?s FM, Madeira MH, Salinas-Navarro M, Jim?nez-L?pez M, Galindo-Romero C, Ort?n-Mart?nez A, Santiago AR, Vidal-Sanz M, Agudo-Barriuso M
Investigative ophthalmology & visual science56(8)4309-23(2015 Jul)

Phosphorylation of rat melanopsin at Ser-381 and Ser-398 by light/dark and its importance for intrinsically photosensitive ganglion cells (ipRGCs) cellular Ca2+ signaling.
Fahrenkrug J, Falktoft B, Georg B, Hannibal J, Kristiansen SB, Klausen TK
The Journal of biological chemistry289(51)35482-93(2014 Dec)

Controlling the number of melanopsin-containing retinal ganglion cells by early light exposure.
Hong J, Zeng Q, Wang H, Kuo DS, Baldridge WH, Wang N
Experimental eye research11117-26(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

during retinal degeneration, the expression of melanopsin was significantly decreased, while vector-mediated overexpression of melanopsin delayed the loss of visual function in rats.
Title: Overexpression of melanopsin in the retina restores visual function in Royal College of Surgeons rats.

Following ON injury or retrograde tracing there is a transient melanopsin downregulation that should be taken into account when assessing m(+)RGC survival.
Title: Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats.

Data indicate that the phosphorylation status of melanopsin influences its functions.
Title: Phosphorylation of rat melanopsin at Ser-381 and Ser-398 by light/dark and its importance for intrinsically photosensitive ganglion cells (ipRGCs) cellular Ca2+ signaling.

Early light exposure can increase the number of melanopsin immunopositive retinal ganalion cells through a process dependent on intrinsic photosensitive spiking activity.
Title: Controlling the number of melanopsin-containing retinal ganglion cells by early light exposure.

We found that light and darkness are important for regulation of melanopsin protein expression whereas input from a retinal networks regulates melanopsin mRNA expression.
Title: Differential expression of melanopsin mRNA and protein in Brown Norwegian rats.

The following Opn4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Opn4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01787	NM_138860.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00
ORa01787	XM_017599989.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00
ORa01787	XM_017599988.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00
ORa58745	XM_017599985.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa58746	XM_017599986.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa58747	XM_017599987.1 Latest version!	Rattus norvegicus opsin 4 (Opn4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Opn4 ( NM_138860.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620215.1 Rattus norvegicus opsin 4 (Opn4), mRNA.

Price & Availability↑

CloneID	ORa01787
Clone ID Related Accession (Same CDS sequence)	NM_138860.1 , XM_017599988.1 , XM_017599989.1
Accession Version	NM_138860.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY072689.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY072689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620215.1
CDS	199..1623
Translation	MNSPSESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	NM_138860.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138860.1

ORF Insert Sequence:

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Opn4 ( XM_017599988.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455477.1 Rattus norvegicus opsin 4 (Opn4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa01787
Clone ID Related Accession (Same CDS sequence)	NM_138860.1 , XM_017599988.1 , XM_017599989.1
Accession Version	XM_017599988.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455477.1
CDS	575..1999
Translation	MNSPSESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	XM_017599988.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599988.1

ORF Insert Sequence:

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Opn4 ( XM_017599989.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455478.1 Rattus norvegicus opsin 4 (Opn4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa01787
Clone ID Related Accession (Same CDS sequence)	NM_138860.1 , XM_017599988.1 , XM_017599989.1
Accession Version	XM_017599989.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455478.1
CDS	530..1954
Translation	MNSPSESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	XM_017599989.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599989.1

ORF Insert Sequence:

ATGAACTCTC CTTCAGAATC AAGAGTCCCT TCAAGCTTAA CTCAGGATCC CAGCTTTACC 
GCCAGCCCTG CCCTCCTACA AGGCATTTGG AACAGCACTC AGAACATCTC CGTCAGAGTC 
CAGCTTCTAT CCGTTAGCCC CACGACACCT GGGCTTCAGG CTGCTGCCTG GGTCCCCTTC 
CCCACAGTCG ACGTCCCAGA TCATGCTCAC TATACCCTAG GCACGGTGAT CCTGCTGGTG 
GGACTCACAG GGATGCTGGG TAACCTGACA GTCATCTACA CCTTCTGCAG GAATAGAGGC 
CTGCGGACAC CGGCAAACAT GCTCATCATC AACCTGGCAG TCAGCGACTT CCTTATGTCG 
TTCACTCAGG CCCCGGTCTT CTTTGCCAGC AGCCTCTACA AGAAGTGGCT CTTCGGGGAG 
ACAGGTTGCA AGTTCTATGC CTTCTGTGGG GCTGTCTTTG GCATCGTTTC CATGATCACC 
CTGACAGCCA TAGCCATGGA CCGCTATCTG GTGATCACAC GTCCACTGGC CACCATCGGC 
ATGAGATCCA AGAGACGGAC GGCACTAGTC CTGCTAGGTG TCTGGCTCTA TGCCCTGGCC 
TGGAGTCTGC CGCCTTTCTT TGGCTGGAGC GCCTACGTGC CCGAGGGGCT GCTGACATCC 
TGCTCCTGGG ACTACGTGAC CTTCACGCCC CTCGTGCGCG CCTACACCAT GCTGCTCTTC 
TGCTTTGTCT TCTTCCTCCC TCTGCTCATT ATCATCTTCT GCTACATCTT CATCTTCAGG 
GCCATTCGAG AGACAGGCCG GGCCTGTGAG GGCTGTGGTG AGTCCCCTCT GCGGCGGCGG 
CAGTGGCAGC GGCTACAGAG TGAATGGAAG ATGGCCAAGG TCGCACTGAT CGTCATTCTC 
CTCTTTGTGC TGTCCTGGGC TCCCTACTCC ACTGTGGCCC TGGTGGGCTT TGCTGGGTAC 
TCGCACATCC TGACGCCCTA CATGAGCTCG GTGCCAGCCG TCATTGCCAA GGCCTCGGCC 
ATCCACAATC CTATCATCTA TGCCATCACT CACCCCAAGT ACAGGGCGGC CATTGCTCAG 
CACTTGCCTT GCCTTGGGGT GCTTCTTGGA GTATCAGGCC AGCGCAGCCA CCCCTCCCTC 
AGCTACCGCT CTACCCATCG CTCCACACTG AGCAGCCAGT CCTCAGACCT CAGCTGGATC 
TCTGGGCAGA AGCGCCAAGA GTCCCTGGGT TCTGAGAGTG AAGTGGGCTG GACAGACACA 
GAAACAACAG CTGCGTGGGG AGCTGCCCAG CAAGCAAGTG GACAATCCTT CTGCAGTCAT 
GACCTGGAAG ATGGAGAAGT CAAGGCTCCT TCCAGCCCCC AGGAACAGAA ATCCAAGACT 
CCCAAGACCA AGAGACACCT CCCCAGTCTG GACCGAAGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Opn4 ( XM_017599985.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455474.1 Rattus norvegicus opsin 4 (Opn4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58745
Clone ID Related Accession (Same CDS sequence)	XM_017599985.1
Accession Version	XM_017599985.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGTGG TCAATTGTCA AGTTGAAAGC TTGCTCTGTG GGCTTCCCTC ACATGTTCTC 
TTAGCCTTTT GTCTCCTAAG TCCTCAAGGG CAGTGCCGAG GCCTAATGGG AAGAAGAGAA 
AATCTGCACT GTTTACAGCT TTGGGATTTC GCTGCCATGT TGACAACCAC GGCAAAAGAC 
ACCTGCAGTT TGTATGCAGA ACCATCCTGG GGCTGCACCA ACATAAGCTA TGGCTGGTGG 
GATAGAGCCA GAGCAGACCC AGAATCAAGA GTCCCTTCAA GCTTAACTCA GGATCCCAGC 
TTTACCGCCA GCCCTGCCCT CCTACAAGGC ATTTGGAACA GCACTCAGAA CATCTCCGTC 
AGAGTCCAGC TTCTATCCGT TAGCCCCACG ACACCTGGGC TTCAGGCTGC TGCCTGGGTC 
CCCTTCCCCA CAGTCGACGT CCCAGATCAT GCTCACTATA CCCTAGGCAC GGTGATCCTG 
CTGGTGGGAC TCACAGGGAT GCTGGGTAAC CTGACAGTCA TCTACACCTT CTGCAGGAAT 
AGAGGCCTGC GGACACCGGC AAACATGCTC ATCATCAACC TGGCAGTCAG CGACTTCCTT 
ATGTCGTTCA CTCAGGCCCC GGTCTTCTTT GCCAGCAGCC TCTACAAGAA GTGGCTCTTC 
GGGGAGACAG GTTGCAAGTT CTATGCCTTC TGTGGGGCTG TCTTTGGCAT CGTTTCCATG 
ATCACCCTGA CAGCCATAGC CATGGACCGC TATCTGGTGA TCACACGTCC ACTGGCCACC 
ATCGGCATGA GATCCAAGAG ACGGACGGCA CTAGTCCTGC TAGGTGTCTG GCTCTATGCC 
CTGGCCTGGA GTCTGCCGCC TTTCTTTGGC TGGAGCGCCT ACGTGCCCGA GGGGCTGCTG 
ACATCCTGCT CCTGGGACTA CGTGACCTTC ACGCCCCTCG TGCGCGCCTA CACCATGCTG 
CTCTTCTGCT TTGTCTTCTT CCTCCCTCTG CTCATTATCA TCTTCTGCTA CATCTTCATC 
TTCAGGGCCA TTCGAGAGAC AGGCCGGGCC TGTGAGGGCT GTGGTGAGTC CCCTCTGCGG 
CGGCGGCAGT GGCAGCGGCT ACAGAGTGAA TGGAAGATGG CCAAGGTCGC ACTGATCGTC 
ATTCTCCTCT TTGTGCTGTC CTGGGCTCCC TACTCCACTG TGGCCCTGGT GGGCTTTGCT 
GGGTACTCGC ACATCCTGAC GCCCTACATG AGCTCGGTGC CAGCCGTCAT TGCCAAGGCC 
TCGGCCATCC ACAATCCTAT CATCTATGCC ATCACTCACC CCAAGTACAG GGCGGCCATT 
GCTCAGCACT TGCCTTGCCT TGGGGTGCTT CTTGGAGTAT CAGGCCAGCG CAGCCACCCC 
TCCCTCAGCT ACCGCTCTAC CCATCGCTCC ACACTGAGCA GCCAGTCCTC AGACCTCAGC 
TGGATCTCTG GGCAGAAGCG CCAAGAGTCC CTGGGTTCTG AGAGTGAAGT GGGCTGGACA 
GACACAGAAA CAACAGCTGC GTGGGGAGCT GCCCAGCAAG CAAGTGGACA ATCCTTCTGC 
AGTCATGACC TGGAAGATGG AGAAGTCAAG GCTCCTTCCA GCCCCCAGGA ACAGAAATCC 
AAGACTCCCA AGACCAAGAG ACACCTCCCC AGTCTGGACC GAAGGATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455474.1
CDS	716..2386
Translation	MCVVNCQVESLLCGLPSHVLLAFCLLSPQGQCRGLMGRRENLHCLQLWDFAAMLTTTAKDTCSLYAEPSWGCTNISYGWWDRARADPESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	XM_017599985.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599985.1

ORF Insert Sequence:

ATGTGTGTGG TCAATTGTCA AGTTGAAAGC TTGCTCTGTG GGCTTCCCTC ACATGTTCTC 
TTAGCCTTTT GTCTCCTAAG TCCTCAAGGG CAGTGCCGAG GCCTAATGGG AAGAAGAGAA 
AATCTGCACT GTTTACAGCT TTGGGATTTC GCTGCCATGT TGACAACCAC GGCAAAAGAC 
ACCTGCAGTT TGTATGCAGA ACCATCCTGG GGCTGCACCA ACATAAGCTA TGGCTGGTGG 
GATAGAGCCA GAGCAGACCC AGAATCAAGA GTCCCTTCAA GCTTAACTCA GGATCCCAGC 
TTTACCGCCA GCCCTGCCCT CCTACAAGGC ATTTGGAACA GCACTCAGAA CATCTCCGTC 
AGAGTCCAGC TTCTATCCGT TAGCCCCACG ACACCTGGGC TTCAGGCTGC TGCCTGGGTC 
CCCTTCCCCA CAGTCGACGT CCCAGATCAT GCTCACTATA CCCTAGGCAC GGTGATCCTG 
CTGGTGGGAC TCACAGGGAT GCTGGGTAAC CTGACAGTCA TCTACACCTT CTGCAGGAAT 
AGAGGCCTGC GGACACCGGC AAACATGCTC ATCATCAACC TGGCAGTCAG CGACTTCCTT 
ATGTCGTTCA CTCAGGCCCC GGTCTTCTTT GCCAGCAGCC TCTACAAGAA GTGGCTCTTC 
GGGGAGACAG GTTGCAAGTT CTATGCCTTC TGTGGGGCTG TCTTTGGCAT CGTTTCCATG 
ATCACCCTGA CAGCCATAGC CATGGACCGC TATCTGGTGA TCACACGTCC ACTGGCCACC 
ATCGGCATGA GATCCAAGAG ACGGACGGCA CTAGTCCTGC TAGGTGTCTG GCTCTATGCC 
CTGGCCTGGA GTCTGCCGCC TTTCTTTGGC TGGAGCGCCT ACGTGCCCGA GGGGCTGCTG 
ACATCCTGCT CCTGGGACTA CGTGACCTTC ACGCCCCTCG TGCGCGCCTA CACCATGCTG 
CTCTTCTGCT TTGTCTTCTT CCTCCCTCTG CTCATTATCA TCTTCTGCTA CATCTTCATC 
TTCAGGGCCA TTCGAGAGAC AGGCCGGGCC TGTGAGGGCT GTGGTGAGTC CCCTCTGCGG 
CGGCGGCAGT GGCAGCGGCT ACAGAGTGAA TGGAAGATGG CCAAGGTCGC ACTGATCGTC 
ATTCTCCTCT TTGTGCTGTC CTGGGCTCCC TACTCCACTG TGGCCCTGGT GGGCTTTGCT 
GGGTACTCGC ACATCCTGAC GCCCTACATG AGCTCGGTGC CAGCCGTCAT TGCCAAGGCC 
TCGGCCATCC ACAATCCTAT CATCTATGCC ATCACTCACC CCAAGTACAG GGCGGCCATT 
GCTCAGCACT TGCCTTGCCT TGGGGTGCTT CTTGGAGTAT CAGGCCAGCG CAGCCACCCC 
TCCCTCAGCT ACCGCTCTAC CCATCGCTCC ACACTGAGCA GCCAGTCCTC AGACCTCAGC 
TGGATCTCTG GGCAGAAGCG CCAAGAGTCC CTGGGTTCTG AGAGTGAAGT GGGCTGGACA 
GACACAGAAA CAACAGCTGC GTGGGGAGCT GCCCAGCAAG CAAGTGGACA ATCCTTCTGC 
AGTCATGACC TGGAAGATGG AGAAGTCAAG GCTCCTTCCA GCCCCCAGGA ACAGAAATCC 
AAGACTCCCA AGACCAAGAG ACACCTCCCC AGTCTGGACC GAAGGATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Opn4 ( XM_017599986.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455475.1 Rattus norvegicus opsin 4 (Opn4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa58746
Clone ID Related Accession (Same CDS sequence)	XM_017599986.1
Accession Version	XM_017599986.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGTGG TCAATTGTCA AGTTGAAAGC TTGCTCTGTG GGCTTCCCTC ACATGTTCTC 
TTAGCCTTTT GTCTCCTAAG TCCTCAAGGG CAGTGCCGAG GCCTAATGGG AAGAAGAGAA 
AATCTGCACT GTTTACAGCT TTGGGATTTC GCTGCCATGT TGACAACCAC GGCAAAAGAC 
ACCTGCAGTT TGTATGCAGA ACCATCCTGG GGCTGCACCA ACATAAGCTA TGGCTGGTGG 
GATAGAGCCA GAGCAGACCC AGAATCAAGA GTCCCTTCAA GCTTAACTCA GGATCCCAGC 
TTTACCGCCA GCCCTGCCCT CCTACAAGGC ATTTGGAACA GCACTCAGAA CATCTCCGTC 
AGAGTCCAGC TTCTATCCGT TAGCCCCACG ACACCTGGGC TTCAGGCTGC TGCCTGGGTC 
CCCTTCCCCA CAGTCGACGT CCCAGATCAT GCTCACTATA CCCTAGGCAC GGTGATCCTG 
CTGGTGGGAC TCACAGGGAT GCTGGGTAAC CTGACAGTCA TCTACACCTT CTGCAGGAAT 
AGAGGCCTGC GGACACCGGC AAACATGCTC ATCATCAACC TGGCAGTCAG CGACTTCCTT 
ATGTCGTTCA CTCAGGCCCC GGTCTTCTTT GCCAGCAGCC TCTACAAGAA GTGGCTCTTC 
GGGGAGACAG CCATAGCCAT GGACCGCTAT CTGGTGATCA CACGTCCACT GGCCACCATC 
GGCATGAGAT CCAAGAGACG GACGGCACTA GTCCTGCTAG GTGTCTGGCT CTATGCCCTG 
GCCTGGAGTC TGCCGCCTTT CTTTGGCTGG AGCGCCTACG TGCCCGAGGG GCTGCTGACA 
TCCTGCTCCT GGGACTACGT GACCTTCACG CCCCTCGTGC GCGCCTACAC CATGCTGCTC 
TTCTGCTTTG TCTTCTTCCT CCCTCTGCTC ATTATCATCT TCTGCTACAT CTTCATCTTC 
AGGGCCATTC GAGAGACAGG CCGGGCCTGT GAGGGCTGTG GTGAGTCCCC TCTGCGGCGG 
CGGCAGTGGC AGCGGCTACA GAGTGAATGG AAGATGGCCA AGGTCGCACT GATCGTCATT 
CTCCTCTTTG TGCTGTCCTG GGCTCCCTAC TCCACTGTGG CCCTGGTGGG CTTTGCTGGG 
TACTCGCACA TCCTGACGCC CTACATGAGC TCGGTGCCAG CCGTCATTGC CAAGGCCTCG 
GCCATCCACA ATCCTATCAT CTATGCCATC ACTCACCCCA AGTACAGGGC GGCCATTGCT 
CAGCACTTGC CTTGCCTTGG GGTGCTTCTT GGAGTATCAG GCCAGCGCAG CCACCCCTCC 
CTCAGCTACC GCTCTACCCA TCGCTCCACA CTGAGCAGCC AGTCCTCAGA CCTCAGCTGG 
ATCTCTGGGC AGAAGCGCCA AGAGTCCCTG GGTTCTGAGA GTGAAGTGGG CTGGACAGAC 
ACAGAAACAA CAGCTGCGTG GGGAGCTGCC CAGCAAGCAA GTGGACAATC CTTCTGCAGT 
CATGACCTGG AAGATGGAGA AGTCAAGGCT CCTTCCAGCC CCCAGGAACA GAAATCCAAG 
ACTCCCAAGA CCAAGAGACA CCTCCCCAGT CTGGACCGAA GGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455475.1
CDS	716..2323
Translation	MCVVNCQVESLLCGLPSHVLLAFCLLSPQGQCRGLMGRRENLHCLQLWDFAAMLTTTAKDTCSLYAEPSWGCTNISYGWWDRARADPESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	XM_017599986.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599986.1

ORF Insert Sequence:

ATGTGTGTGG TCAATTGTCA AGTTGAAAGC TTGCTCTGTG GGCTTCCCTC ACATGTTCTC 
TTAGCCTTTT GTCTCCTAAG TCCTCAAGGG CAGTGCCGAG GCCTAATGGG AAGAAGAGAA 
AATCTGCACT GTTTACAGCT TTGGGATTTC GCTGCCATGT TGACAACCAC GGCAAAAGAC 
ACCTGCAGTT TGTATGCAGA ACCATCCTGG GGCTGCACCA ACATAAGCTA TGGCTGGTGG 
GATAGAGCCA GAGCAGACCC AGAATCAAGA GTCCCTTCAA GCTTAACTCA GGATCCCAGC 
TTTACCGCCA GCCCTGCCCT CCTACAAGGC ATTTGGAACA GCACTCAGAA CATCTCCGTC 
AGAGTCCAGC TTCTATCCGT TAGCCCCACG ACACCTGGGC TTCAGGCTGC TGCCTGGGTC 
CCCTTCCCCA CAGTCGACGT CCCAGATCAT GCTCACTATA CCCTAGGCAC GGTGATCCTG 
CTGGTGGGAC TCACAGGGAT GCTGGGTAAC CTGACAGTCA TCTACACCTT CTGCAGGAAT 
AGAGGCCTGC GGACACCGGC AAACATGCTC ATCATCAACC TGGCAGTCAG CGACTTCCTT 
ATGTCGTTCA CTCAGGCCCC GGTCTTCTTT GCCAGCAGCC TCTACAAGAA GTGGCTCTTC 
GGGGAGACAG CCATAGCCAT GGACCGCTAT CTGGTGATCA CACGTCCACT GGCCACCATC 
GGCATGAGAT CCAAGAGACG GACGGCACTA GTCCTGCTAG GTGTCTGGCT CTATGCCCTG 
GCCTGGAGTC TGCCGCCTTT CTTTGGCTGG AGCGCCTACG TGCCCGAGGG GCTGCTGACA 
TCCTGCTCCT GGGACTACGT GACCTTCACG CCCCTCGTGC GCGCCTACAC CATGCTGCTC 
TTCTGCTTTG TCTTCTTCCT CCCTCTGCTC ATTATCATCT TCTGCTACAT CTTCATCTTC 
AGGGCCATTC GAGAGACAGG CCGGGCCTGT GAGGGCTGTG GTGAGTCCCC TCTGCGGCGG 
CGGCAGTGGC AGCGGCTACA GAGTGAATGG AAGATGGCCA AGGTCGCACT GATCGTCATT 
CTCCTCTTTG TGCTGTCCTG GGCTCCCTAC TCCACTGTGG CCCTGGTGGG CTTTGCTGGG 
TACTCGCACA TCCTGACGCC CTACATGAGC TCGGTGCCAG CCGTCATTGC CAAGGCCTCG 
GCCATCCACA ATCCTATCAT CTATGCCATC ACTCACCCCA AGTACAGGGC GGCCATTGCT 
CAGCACTTGC CTTGCCTTGG GGTGCTTCTT GGAGTATCAG GCCAGCGCAG CCACCCCTCC 
CTCAGCTACC GCTCTACCCA TCGCTCCACA CTGAGCAGCC AGTCCTCAGA CCTCAGCTGG 
ATCTCTGGGC AGAAGCGCCA AGAGTCCCTG GGTTCTGAGA GTGAAGTGGG CTGGACAGAC 
ACAGAAACAA CAGCTGCGTG GGGAGCTGCC CAGCAAGCAA GTGGACAATC CTTCTGCAGT 
CATGACCTGG AAGATGGAGA AGTCAAGGCT CCTTCCAGCC CCCAGGAACA GAAATCCAAG 
ACTCCCAAGA CCAAGAGACA CCTCCCCAGT CTGGACCGAA GGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Opn4 ( XM_017599987.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455476.1 Rattus norvegicus opsin 4 (Opn4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa58747
Clone ID Related Accession (Same CDS sequence)	XM_017599987.1
Accession Version	XM_017599987.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	melanopsin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAGAA GAGAAAATCT GCACTGTTTA CAGCTTTGGG ATTTCGCTGC CATGTTGACA 
ACCACGGCAA AAGACACCTG CAGTTTGTAT GCAGAACCAT CCTGGGGCTG CACCAACATA 
AGCTATGGCT GGTGGGATAG AGCCAGAGCA GACCCAGAAT CAAGAGTCCC TTCAAGCTTA 
ACTCAGGATC CCAGCTTTAC CGCCAGCCCT GCCCTCCTAC AAGGCATTTG GAACAGCACT 
CAGAACATCT CCGTCAGAGT CCAGCTTCTA TCCGTTAGCC CCACGACACC TGGGCTTCAG 
GCTGCTGCCT GGGTCCCCTT CCCCACAGTC GACGTCCCAG ATCATGCTCA CTATACCCTA 
GGCACGGTGA TCCTGCTGGT GGGACTCACA GGGATGCTGG GTAACCTGAC AGTCATCTAC 
ACCTTCTGCA GGAATAGAGG CCTGCGGACA CCGGCAAACA TGCTCATCAT CAACCTGGCA 
GTCAGCGACT TCCTTATGTC GTTCACTCAG GCCCCGGTCT TCTTTGCCAG CAGCCTCTAC 
AAGAAGTGGC TCTTCGGGGA GACAGGTTGC AAGTTCTATG CCTTCTGTGG GGCTGTCTTT 
GGCATCGTTT CCATGATCAC CCTGACAGCC ATAGCCATGG ACCGCTATCT GGTGATCACA 
CGTCCACTGG CCACCATCGG CATGAGATCC AAGAGACGGA CGGCACTAGT CCTGCTAGGT 
GTCTGGCTCT ATGCCCTGGC CTGGAGTCTG CCGCCTTTCT TTGGCTGGAG CGCCTACGTG 
CCCGAGGGGC TGCTGACATC CTGCTCCTGG GACTACGTGA CCTTCACGCC CCTCGTGCGC 
GCCTACACCA TGCTGCTCTT CTGCTTTGTC TTCTTCCTCC CTCTGCTCAT TATCATCTTC 
TGCTACATCT TCATCTTCAG GGCCATTCGA GAGACAGGCC GGGCCTGTGA GGGCTGTGGT 
GAGTCCCCTC TGCGGCGGCG GCAGTGGCAG CGGCTACAGA GTGAATGGAA GATGGCCAAG 
GTCGCACTGA TCGTCATTCT CCTCTTTGTG CTGTCCTGGG CTCCCTACTC CACTGTGGCC 
CTGGTGGGCT TTGCTGGGTA CTCGCACATC CTGACGCCCT ACATGAGCTC GGTGCCAGCC 
GTCATTGCCA AGGCCTCGGC CATCCACAAT CCTATCATCT ATGCCATCAC TCACCCCAAG 
TACAGGGCGG CCATTGCTCA GCACTTGCCT TGCCTTGGGG TGCTTCTTGG AGTATCAGGC 
CAGCGCAGCC ACCCCTCCCT CAGCTACCGC TCTACCCATC GCTCCACACT GAGCAGCCAG 
TCCTCAGACC TCAGCTGGAT CTCTGGGCAG AAGCGCCAAG AGTCCCTGGG TTCTGAGAGT 
GAAGTGGGCT GGACAGACAC AGAAACAACA GCTGCGTGGG GAGCTGCCCA GCAAGCAAGT 
GGACAATCCT TCTGCAGTCA TGACCTGGAA GATGGAGAAG TCAAGGCTCC TTCCAGCCCC 
CAGGAACAGA AATCCAAGAC TCCCAAGACC AAGAGACACC TCCCCAGTCT GGACCGAAGG 
ATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455476.1
CDS	127..1692
Translation	MGRRENLHCLQLWDFAAMLTTTAKDTCSLYAEPSWGCTNISYGWWDRARADPESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Target ORF information:

RefSeq Version	XM_017599987.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus opsin 4 (Opn4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599987.1

ORF Insert Sequence:

ATGGGAAGAA GAGAAAATCT GCACTGTTTA CAGCTTTGGG ATTTCGCTGC CATGTTGACA 
ACCACGGCAA AAGACACCTG CAGTTTGTAT GCAGAACCAT CCTGGGGCTG CACCAACATA 
AGCTATGGCT GGTGGGATAG AGCCAGAGCA GACCCAGAAT CAAGAGTCCC TTCAAGCTTA 
ACTCAGGATC CCAGCTTTAC CGCCAGCCCT GCCCTCCTAC AAGGCATTTG GAACAGCACT 
CAGAACATCT CCGTCAGAGT CCAGCTTCTA TCCGTTAGCC CCACGACACC TGGGCTTCAG 
GCTGCTGCCT GGGTCCCCTT CCCCACAGTC GACGTCCCAG ATCATGCTCA CTATACCCTA 
GGCACGGTGA TCCTGCTGGT GGGACTCACA GGGATGCTGG GTAACCTGAC AGTCATCTAC 
ACCTTCTGCA GGAATAGAGG CCTGCGGACA CCGGCAAACA TGCTCATCAT CAACCTGGCA 
GTCAGCGACT TCCTTATGTC GTTCACTCAG GCCCCGGTCT TCTTTGCCAG CAGCCTCTAC 
AAGAAGTGGC TCTTCGGGGA GACAGGTTGC AAGTTCTATG CCTTCTGTGG GGCTGTCTTT 
GGCATCGTTT CCATGATCAC CCTGACAGCC ATAGCCATGG ACCGCTATCT GGTGATCACA 
CGTCCACTGG CCACCATCGG CATGAGATCC AAGAGACGGA CGGCACTAGT CCTGCTAGGT 
GTCTGGCTCT ATGCCCTGGC CTGGAGTCTG CCGCCTTTCT TTGGCTGGAG CGCCTACGTG 
CCCGAGGGGC TGCTGACATC CTGCTCCTGG GACTACGTGA CCTTCACGCC CCTCGTGCGC 
GCCTACACCA TGCTGCTCTT CTGCTTTGTC TTCTTCCTCC CTCTGCTCAT TATCATCTTC 
TGCTACATCT TCATCTTCAG GGCCATTCGA GAGACAGGCC GGGCCTGTGA GGGCTGTGGT 
GAGTCCCCTC TGCGGCGGCG GCAGTGGCAG CGGCTACAGA GTGAATGGAA GATGGCCAAG 
GTCGCACTGA TCGTCATTCT CCTCTTTGTG CTGTCCTGGG CTCCCTACTC CACTGTGGCC 
CTGGTGGGCT TTGCTGGGTA CTCGCACATC CTGACGCCCT ACATGAGCTC GGTGCCAGCC 
GTCATTGCCA AGGCCTCGGC CATCCACAAT CCTATCATCT ATGCCATCAC TCACCCCAAG 
TACAGGGCGG CCATTGCTCA GCACTTGCCT TGCCTTGGGG TGCTTCTTGG AGTATCAGGC 
CAGCGCAGCC ACCCCTCCCT CAGCTACCGC TCTACCCATC GCTCCACACT GAGCAGCCAG 
TCCTCAGACC TCAGCTGGAT CTCTGGGCAG AAGCGCCAAG AGTCCCTGGG TTCTGAGAGT 
GAAGTGGGCT GGACAGACAC AGAAACAACA GCTGCGTGGG GAGCTGCCCA GCAAGCAAGT 
GGACAATCCT TCTGCAGTCA TGACCTGGAA GATGGAGAAG TCAAGGCTCC TTCCAGCCCC 
CAGGAACAGA AATCCAAGAC TCCCAAGACC AAGAGACACC TCCCCAGTCT GGACCGAAGG 
ATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of melanopsin in the retina restores visual function in Royal College of Surgeons rats.
Molecular medicine reports13(1)321-6(2016 Jan)
Liu M,Dai J,Liu W,Zhao C,Yin ZQ

Isoforms of Melanopsin Mediate Different Behavioral Responses to Light.
Current biology : CB25(18)2430-4(2015 Sep)
Jagannath A,Hughes S,Abdelgany A,Pothecary CA,Di Pretoro S,Pires SS,Vachtsevanos A,Pilorz V,Brown LA,Hossbach M,MacLaren RE,Halford S,Gatti S,Hankins MW,Wood MJ,Foster RG,Peirson SN

Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats.
Investigative ophthalmology & visual science56(8)4309-23(2015 Jul)
Nadal-Nicol?s FM,Madeira MH,Salinas-Navarro M,Jim?nez-L?pez M,Galindo-Romero C,Ort?n-Mart?nez A,Santiago AR,Vidal-Sanz M,Agudo-Barriuso M

Phosphorylation of rat melanopsin at Ser-381 and Ser-398 by light/dark and its importance for intrinsically photosensitive ganglion cells (ipRGCs) cellular Ca2+ signaling.
The Journal of biological chemistry289(51)35482-93(2014 Dec)
Fahrenkrug J,Falktoft B,Georg B,Hannibal J,Kristiansen SB,Klausen TK

Controlling the number of melanopsin-containing retinal ganglion cells by early light exposure.
Experimental eye research11117-26(2013 Jun)
Hong J,Zeng Q,Wang H,Kuo DS,Baldridge WH,Wang N

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Opn4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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