Tecr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tecr
Entrez Gene ID	191576
Full Name	trans-2,3-enoyl-CoA reductase
Synonyms	Gpsn2,SC2
General protein information	Preferred Names trans-2,3-enoyl-CoA reductase Names very-long-chain enoyl-CoA reductase TER glycoprotein, synaptic 2 neuroprotective protein 13 synaptic glycoprotein SC2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19q11
Summary	synaptic glycoprotein expressed in many types of neurons [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006255218.3	XP_006255280.1	very-long-chain enoyl-CoA reductase isoform X1
NM_138549.1	NP_612558.1	very-long-chain enoyl-CoA reductase

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	tecrb	NP_958456.1
Saccharomyces cerevisiae (baker's yeast)	TSC13	NP_010269.1
Arabidopsis thaliana (thale cress)	CER10	NP_191096.1
Canis lupus familiaris (dog)	TECR	XP_852850.1
Mus musculus (house mouse)	Tecr	NP_598879.1
Kluyveromyces lactis	KLLA0C04367g	XP_452392.1
Oryza sativa (rice)	Os01g0150000	NP_001042030.1
Xenopus tropicalis (tropical clawed frog)	tecr	NP_001008199.1
Bos taurus (cattle)	TECR	NP_001029920.1
Gallus gallus (chicken)	TECR	XP_004936640.1
Caenorhabditis elegans (roundworm)	art-1	NP_495430.1
Eremothecium gossypii	AGOS_AER215W	NP_985072.1
Neurospora crassa	NCU03362	XP_956297.1
Homo sapiens (human)	TECR	NP_612510.1
Schizosaccharomyces pombe (fission yeast)	SPBC646.07c	NP_595365.1
Pan troglodytes (chimpanzee)	TECR	XP_512444.3
Rattus norvegicus (Norway rat)	Tecr	NP_612558.1
Drosophila melanogaster (fruit fly)	Sc2	NP_647836.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010714	XP_311426.1
Magnaporthe oryzae (rice blast fungus)	MGG_03250	XP_003716724.1

Gene Ontology
Bibliography

Related articles in PubMed

Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation.
Wakashima T, Abe K, Kihara A
The Journal of biological chemistry289(36)24736-48(2014 Sep)

Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile.
Abe K, Ohno Y, Sassa T, Taguchi R, ?al??kan M, Ober C, Kihara A
The Journal of biological chemistry288(51)36741-9(2013 Dec)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Functional identification of neuroprotective molecules.
Dai C, Liang D, Li H, Sasaki M, Dawson TM, Dawson VL
PloS one5(11)e15008(2010 Nov)

Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
Moon YA, Horton JD
The Journal of biological chemistry278(9)7335-43(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tecr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tecr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01637	NM_138549.1 Latest version!	Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa38673	XM_006255218.3 Latest version!	Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tecr ( NM_138549.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_612558.1 Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), mRNA.

Price & Availability↑

CloneID	ORa01637
Clone ID Related Accession (Same CDS sequence)	NM_138549.1
Accession Version	NM_138549.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Rattus norvegicus(Norway rat)
Product	very-long-chain enoyl-CoA reductase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S45663.1. On Jun 25, 2006 this sequence version replaced XM_001072883.1. ##Evidence-Data-START## Transcript exon combination :: FQ220726.1, BC059115.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAAGCACT ACGAGGTGGA GATTCGGGAT GCAAAGACGA GGGAGAAGCT GTGCTTCCTG 
GACAAGGTAG AGCCTCAGGC CACCATTTCT GAAATCAAGA CCCTTTTCAC CAAGACACAC 
CCGCAGTGGT ATCCTGCCCG CCAGTCCCTC CGCCTGGACC CCAAGGGGAA GTCCCTGAAA 
GATGAAGATG TGTTGCAGAA GCTTCCTGTG GGCACCACAG CTACGCTCTA CTTCCGGGAC 
CTCGGGGCCC AGATCAGCTG GGTGACGGTC TTCCTGACGG AGTATGCTGG GCCCCTTTTC 
ATCTACCTGC TCTTCTACTT CCGGGTGCCC TTCATTTATG GCCGCAAATA CGACTTTACA 
TCCAGTCGGC ATACTGTGGT GCACCTCGCC TGCATGTGCC ACTCCTTCCA CTACATCAAG 
CGCCTGCTGG AGACTCTCTT CGTGCACCGA TTCTCTCACG GAACCATGCC CCTGCGAAAC 
ATCTTCAAAA ACTGCACCTA CTACTGGGGC TTTGCTGCGT GGATGGCTTA TTACATCAAC 
CACCCTCTCT ACACACCCCC TACCTATGGA GTTCAGCAGG TTAAGCTGGC ACTGGCCATT 
TTTGTGATCT GTCAGCTTGG GAACTTCTCT ATCCACATGG CTCTCCGGGA TCTTCGACCA 
GCGGGGTCGA AAACCAGGAA GATCCCATAC CCCACCAAGA ACCCCTTCAC CTGGCTGTTT 
CTGTTGGTGT CCTGTCCCAA CTACACTTAC GAGGTCGGCT CCTGGATTGG CTTTGCCATT 
ATGACACAGT GTGTCCCAGT GGCCCTCTTC TCCCTGGTGG GCTTCACCCA GATGACTATC 
TGGGCCAAGG GCAAGCATCG CAGCTACCTG AAGGAGTTCC GTGACTACCC ACCCCTGCGC 
ATGCCCATAA TCCCCTTCCT GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612558.1
CDS	140..1066
Translation	MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTHPQWYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGRKYDFTSSRHTVVHLACMCHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHPLYTPPTYGVQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCVPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL

Target ORF information:

RefSeq Version	NM_138549.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138549.1

ORF Insert Sequence:

ATGAAGCACT ACGAGGTGGA GATTCGGGAT GCAAAGACGA GGGAGAAGCT GTGCTTCCTG 
GACAAGGTAG AGCCTCAGGC CACCATTTCT GAAATCAAGA CCCTTTTCAC CAAGACACAC 
CCGCAGTGGT ATCCTGCCCG CCAGTCCCTC CGCCTGGACC CCAAGGGGAA GTCCCTGAAA 
GATGAAGATG TGTTGCAGAA GCTTCCTGTG GGCACCACAG CTACGCTCTA CTTCCGGGAC 
CTCGGGGCCC AGATCAGCTG GGTGACGGTC TTCCTGACGG AGTATGCTGG GCCCCTTTTC 
ATCTACCTGC TCTTCTACTT CCGGGTGCCC TTCATTTATG GCCGCAAATA CGACTTTACA 
TCCAGTCGGC ATACTGTGGT GCACCTCGCC TGCATGTGCC ACTCCTTCCA CTACATCAAG 
CGCCTGCTGG AGACTCTCTT CGTGCACCGA TTCTCTCACG GAACCATGCC CCTGCGAAAC 
ATCTTCAAAA ACTGCACCTA CTACTGGGGC TTTGCTGCGT GGATGGCTTA TTACATCAAC 
CACCCTCTCT ACACACCCCC TACCTATGGA GTTCAGCAGG TTAAGCTGGC ACTGGCCATT 
TTTGTGATCT GTCAGCTTGG GAACTTCTCT ATCCACATGG CTCTCCGGGA TCTTCGACCA 
GCGGGGTCGA AAACCAGGAA GATCCCATAC CCCACCAAGA ACCCCTTCAC CTGGCTGTTT 
CTGTTGGTGT CCTGTCCCAA CTACACTTAC GAGGTCGGCT CCTGGATTGG CTTTGCCATT 
ATGACACAGT GTGTCCCAGT GGCCCTCTTC TCCCTGGTGG GCTTCACCCA GATGACTATC 
TGGGCCAAGG GCAAGCATCG CAGCTACCTG AAGGAGTTCC GTGACTACCC ACCCCTGCGC 
ATGCCCATAA TCCCCTTCCT GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tecr ( XM_006255218.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255280.1 Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa38673
Clone ID Related Accession (Same CDS sequence)	XM_006255218.3
Accession Version	XM_006255218.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	very-long-chain enoyl-CoA reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255218.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCACT ACGAGGTGGA GATTCGGGAT GCAAAGACGA GGGAGAAGCT GTGCTTCCTG 
GACAAGGTAG AGCCTCAGGC CACCATTTCT GAAATCAAGA CCCTTTTCAC CAAGACACAG 
GGGAAGTCCC TGAAAGATGA AGATGTGTTG CAGAAGCTTC CTGTGGGCAC CACAGCTACG 
CTCTACTTCC GGGACCTCGG GGCCCAGATC AGCTGGGTGA CGGTCTTCCT GACGGAGTAT 
GCTGGGCCCC TTTTCATCTA CCTGCTCTTC TACTTCCGGG TGCCCTTCAT TTATGGCCGC 
AAATACGACT TTACATCCAG TCGGCATACT GTGGTGCACC TCGCCTGCAT GTGCCACTCC 
TTCCACTACA TCAAGCGCCT GCTGGAGACT CTCTTCGTGC ACCGATTCTC TCACGGAACC 
ATGCCCCTGC GAAACATCTT CAAAAACTGC ACCTACTACT GGGGCTTTGC TGCGTGGATG 
GCTTATTACA TCAACCACCC TCTCTACACA CCCCCTACCT ATGGAGTTCA GCAGGTTAAG 
CTGGCACTGG CCATTTTTGT GATCTGTCAG CTTGGGAACT TCTCTATCCA CATGGCTCTC 
CGGGATCTTC GACCAGCGGG GTCGAAAACC AGGAAGATCC CATACCCCAC CAAGAACCCC 
TTCACCTGGC TGTTTCTGTT GGTGTCCTGT CCCAACTACA CTTACGAGGT CGGCTCCTGG 
ATTGGCTTTG CCATTATGAC ACAGTGTGTC CCAGTGGCCC TCTTCTCCCT GGTGGGCTTC 
ACCCAGATGA CTATCTGGGC CAAGGGCAAG CATCGCAGCT ACCTGAAGGA GTTCCGTGAC 
TACCCACCCC TGCGCATGCC CATAATCCCC TTCCTGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255280.1
CDS	139..1020
Translation	MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTQGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGRKYDFTSSRHTVVHLACMCHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHPLYTPPTYGVQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCVPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL

Target ORF information:

RefSeq Version	XM_006255218.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus trans-2,3-enoyl-CoA reductase (Tecr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255218.3

ORF Insert Sequence:

ATGAAGCACT ACGAGGTGGA GATTCGGGAT GCAAAGACGA GGGAGAAGCT GTGCTTCCTG 
GACAAGGTAG AGCCTCAGGC CACCATTTCT GAAATCAAGA CCCTTTTCAC CAAGACACAG 
GGGAAGTCCC TGAAAGATGA AGATGTGTTG CAGAAGCTTC CTGTGGGCAC CACAGCTACG 
CTCTACTTCC GGGACCTCGG GGCCCAGATC AGCTGGGTGA CGGTCTTCCT GACGGAGTAT 
GCTGGGCCCC TTTTCATCTA CCTGCTCTTC TACTTCCGGG TGCCCTTCAT TTATGGCCGC 
AAATACGACT TTACATCCAG TCGGCATACT GTGGTGCACC TCGCCTGCAT GTGCCACTCC 
TTCCACTACA TCAAGCGCCT GCTGGAGACT CTCTTCGTGC ACCGATTCTC TCACGGAACC 
ATGCCCCTGC GAAACATCTT CAAAAACTGC ACCTACTACT GGGGCTTTGC TGCGTGGATG 
GCTTATTACA TCAACCACCC TCTCTACACA CCCCCTACCT ATGGAGTTCA GCAGGTTAAG 
CTGGCACTGG CCATTTTTGT GATCTGTCAG CTTGGGAACT TCTCTATCCA CATGGCTCTC 
CGGGATCTTC GACCAGCGGG GTCGAAAACC AGGAAGATCC CATACCCCAC CAAGAACCCC 
TTCACCTGGC TGTTTCTGTT GGTGTCCTGT CCCAACTACA CTTACGAGGT CGGCTCCTGG 
ATTGGCTTTG CCATTATGAC ACAGTGTGTC CCAGTGGCCC TCTTCTCCCT GGTGGGCTTC 
ACCCAGATGA CTATCTGGGC CAAGGGCAAG CATCGCAGCT ACCTGAAGGA GTTCCGTGAC 
TACCCACCCC TGCGCATGCC CATAATCCCC TTCCTGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation.
The Journal of biological chemistry289(36)24736-48(2014 Sep)
Wakashima T,Abe K,Kihara A

Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile.
The Journal of biological chemistry288(51)36741-9(2013 Dec)
Abe K,Ohno Y,Sassa T,Taguchi R,?al??kan M,Ober C,Kihara A

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Functional identification of neuroprotective molecules.
PloS one5(11)e15008(2010 Nov)
Dai C,Liang D,Li H,Sasaki M,Dawson TM,Dawson VL

Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
The Journal of biological chemistry278(9)7335-43(2003 Feb)
Moon YA,Horton JD