Khsrp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Khsrp
Entrez Gene ID	171137
Full Name	KH-type splicing regulatory protein
Synonyms	Marta1
General protein information	Preferred Names KH-type splicing regulatory protein Names far upstream element-binding protein 2 FUSE-binding protein 2 KSRP MAP2 RNA trans-acting protein 1 MAP2 RNA trans-acting protein MARTA1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q12
Summary	binds to the microtubule-associated protein 2 (Map2) 3 dendritic targeting element; may play a role in nucleocytoplasmic mRNA targeting [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133602.1	NP_598286.1	far upstream element-binding protein 2
XM_006244292.3	XP_006244354.1	far upstream element-binding protein 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KHSRP	NP_003676.2
Rattus norvegicus (Norway rat)	Khsrp	NP_598286.1
Pan troglodytes (chimpanzee)	KHSRP	XP_512315.3
Danio rerio (zebrafish)	khsrp	NP_001082897.1
Xenopus tropicalis (tropical clawed frog)	khsrp	NP_001123831.2
Bos taurus (cattle)	KHSRP	XP_003586314.2
Mus musculus (house mouse)	Khsrp	NP_034743.3

Gene Ontology
Bibliography

Related articles in PubMed

The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
Connerty P, Bajan S, Remenyi J, Fuller-Pace FV, Hutvagner G
Biochimica et biophysica acta1859(10)1299-305(2016 10)

microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator.
Jiang H, Zhang J, Du Y, Jia X, Yang F, Si S, Wang L, Hong B
Atherosclerosis243(2)523-32(2015 Dec)

Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.
Zhu X, Yao L, Yang X, Sun H, Guo A, Li A, Yang H
The international journal of biochemistry & cell biology481-10(2014 Mar)

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.
Bird CW, Gardiner AS, Bolognani F, Tanner DC, Chen CY, Lin WJ, Yoo S, Twiss JL, Perrone-Bizzozero N
PloS one8(11)e79255(2013)

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.
Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M
PLoS genetics8(7)e1002823(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Authors speculated that KHSRP was involved in SCs and neuronal differentiation by inducing beta-catenin mRNA decay.
Title: Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.
Title: KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

The following Khsrp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Khsrp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01046	NM_133602.1 Latest version!	Rattus norvegicus KH-type splicing regulatory protein (Khsrp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price
ORa31870	XM_006244292.3 Latest version!	Rattus norvegicus KH-type splicing regulatory protein (Khsrp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Khsrp ( NM_133602.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598286.1 Rattus norvegicus KH-type splicing regulatory protein (Khsrp), mRNA.

Price & Availability↑

CloneID	ORa01046
Clone ID Related Accession (Same CDS sequence)	NM_133602.1
Accession Version	NM_133602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	far upstream element-binding protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF308818.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF308818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGGACT ACAGCACGGG AGGTCCCCCG CCCGGCCCGC CGCCTCCCGC TGGCGGAGGA 
GGAGGAGCCG CGGGTGCGGG AGGAGGCCCT CCGCCGGGCC CGCCGGGTGC GGGAGACCGG 
GGCGGCGGAG GCCCTGGCGG CGGCGGCCCG GGTGGAGGAG GCGCGTCCGG GGGCCCTTCG 
CAGCCTCCGG GTGGCGGCGG TCCGGGGATA CGCAAGGACG CCTTCGCCGA CGCCGTRCAG 
CGGGCCCGCC AGATTGCAGC CAAAATCGGA GGTGATGCTG CTACCACCGT GAATAACAAC 
ACTCCTGATT TCGGTTTTGG GGGCCAAAAG AGACAGCTGG AAGATGGAGA CCAGCCAGAC 
AGCAAGAAAC TGGCTTCCCA GGGAGATTCA ATTGGTTCTC AGCTGGGACC CATCCATCCT 
CCCCCCAGGA CCTCAATGAC AGAAGAGTAT AGGGTTCCGG ACGGCATGGT GGGCTTGATC 
ATTGGCAGAG GTGGTGAGCA GATAAACAAA ATCCAGCAGG ACTCAGGCTG CAAAGTTCAG 
ATCTCACCAG ATAGTGGCGG CCTCCCTGAG CGCAGTGTGT CCCTGACTGG AGCACCAGAG 
TCTGTCCAAA AGGCAAAGAT GATGCTGGAT GACATTGTGT CTCGGGGCCG TGGAGGCCCC 
CCAGGACAGT TCCATGACAA CGCCAACGGG GGTCAGAATG GCACAGTGCA GGAGATCATG 
ATCCCTGCTG GCAAGGCTGG CCTGGTCATT GGCAAGGGTG GAGAGACCAT CAAGCAGCTG 
CAGGAGCGGG CTGGGGTGAA GATGATTTTA ATTCAGGACG GCTCCCAGAA CACAAATGTG 
GACAAGCCGC TGCGGATTAT TGGGGACCCA TACAAAGTAC AGCAAGCCTG TGAGATGGTG 
ATGGACATCC TGCGAGAACG TGACCAGGGT GGCTTTGGGG ACCGCAATGA ATACGGATCT 
CGGGTTGGCG GAGGCATCGA TGTGCCTGTA CCCCGGCATT CGGTTGGTGT GGTCATTGGC 
CGGAGTGGAG AGATGATCAA GAAGATCCAG AATGATGCTG GTGTGCGCAT CCAGTTCAAG 
CAAGATGACG GGACCGGCCC TGAGAAGATT GCTCACATCA TGGGGCCTCC AGATCGGTGT 
GAGCATGCAG CCCGGATCAT CAATGACCTC CTCCAGAGTC TTCGGAGTGG GCCCCCAGGT 
CCTCCAGGGG CCCCTGGCAT GCCCCCTGGA GGCCGGGGCC GGGGCCGAGG CCAAGGCAAC 
TGGGGCCCTC CTGGAGGGGA GATGACTTTC TCCATTCCTA CCCATAAATG TGGGCTGGTC 
ATTGGCCGAG GTGGGGAGAA CGTGAAGGCC ATTAACCAGC AGACAGGCGC CTTTGTGGAA 
ATATCTCGGC AGCTGCCGCC CAATGGAGAC CCCAATTTCA AGTTATTTGT CATCCGGGGC 
TCACCTCAGC AGATTGACCA TGCAAAGCAG CTCATTGAGG AGAAGATAGA GGGTCCCCTC 
TGCCCAGTTG GACCAGGCCC TGGGGGACCA GGCCCTGCTG GACCCATGGG GCCTTTCCAC 
CCTGGACCCT TCAACCAGGG GCCTCCAGGG GCACCACCAC ATGCTGGTGG TCCCCCTCCT 
CACCAGTACC CGCCTCAGGG CTGGGGCAAT ACCTACCCCG AGTGGCAACC ACCTGCCCCT 
CATGACCCAA ACAAAGCTGC AGCAGCAGCT ACAGACCCTA ATGCTGCCTG GGCCGCCTAC 
TACTCCCACT ACTACCAGCA ACCCCCAGGC CCCGTGCCAG GCCCTGCCCC AGCCCCTGCA 
GCCCCACCTG CGCAAGGGGA GCCCCCCCAG CCTCCACCTA CTGGCCAATC AGACTATACC 
AAGGCTTGGG AAGAGTATTA CAAAAAAATT GGCCAGCAGC CCCAGCAGCC TGGGGCGCCC 
CCACAGCAGG ATTACACCAA GGCCTGGGAG GAGTACTACA AGAAGCAAGC ACAAGTGGCC 
ACTGGTGGGG GTCCTGGAGC ACCCCCTGGC TCCCAGCCTG ACTACAGTGC CGCCTGGGCT 
GAGTATTACA GACAGCAGGC TGCTTACTAC GGACAGACCC CAGGCCCTGG TGGCCCACAG 
CCACCTTCCA CCCAGCAGGG ACAGCAGCAG GCAACTGAAG CAAATGGATA TGAACTTCAT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598286.1
CDS	1..2166
Translation	MSDYSTGGPPPGPPPPAGGGGGAAGAGGGPPPGPPGAGDRGGGGPGGGGPGGGGASGGPSQPPGGGGPGIRKDAFADAnullQRARQIAAKIGGDAATTVNNNTPDFGFGGQKRQLEDGDQPDSKKLASQGDSIGSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRVGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGAPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFVIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFHPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPEWQPPAPHDPNKAAAAATDPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPSTQQGQQQATEANGYELHL

Target ORF information:

RefSeq Version	NM_133602.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KH-type splicing regulatory protein (Khsrp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133602.1

ORF Insert Sequence:

ATGTCGGACT ACAGCACGGG AGGTCCCCCG CCCGGCCCGC CGCCTCCCGC TGGCGGAGGA 
GGAGGAGCCG CGGGTGCGGG AGGAGGCCCT CCGCCGGGCC CGCCGGGTGC GGGAGACCGG 
GGCGGCGGAG GCCCTGGCGG CGGCGGCCCG GGTGGAGGAG GCGCGTCCGG GGGCCCTTCG 
CAGCCTCCGG GTGGCGGCGG TCCGGGGATA CGCAAGGACG CCTTCGCCGA CGCCGTRCAG 
CGGGCCCGCC AGATTGCAGC CAAAATCGGA GGTGATGCTG CTACCACCGT GAATAACAAC 
ACTCCTGATT TCGGTTTTGG GGGCCAAAAG AGACAGCTGG AAGATGGAGA CCAGCCAGAC 
AGCAAGAAAC TGGCTTCCCA GGGAGATTCA ATTGGTTCTC AGCTGGGACC CATCCATCCT 
CCCCCCAGGA CCTCAATGAC AGAAGAGTAT AGGGTTCCGG ACGGCATGGT GGGCTTGATC 
ATTGGCAGAG GTGGTGAGCA GATAAACAAA ATCCAGCAGG ACTCAGGCTG CAAAGTTCAG 
ATCTCACCAG ATAGTGGCGG CCTCCCTGAG CGCAGTGTGT CCCTGACTGG AGCACCAGAG 
TCTGTCCAAA AGGCAAAGAT GATGCTGGAT GACATTGTGT CTCGGGGCCG TGGAGGCCCC 
CCAGGACAGT TCCATGACAA CGCCAACGGG GGTCAGAATG GCACAGTGCA GGAGATCATG 
ATCCCTGCTG GCAAGGCTGG CCTGGTCATT GGCAAGGGTG GAGAGACCAT CAAGCAGCTG 
CAGGAGCGGG CTGGGGTGAA GATGATTTTA ATTCAGGACG GCTCCCAGAA CACAAATGTG 
GACAAGCCGC TGCGGATTAT TGGGGACCCA TACAAAGTAC AGCAAGCCTG TGAGATGGTG 
ATGGACATCC TGCGAGAACG TGACCAGGGT GGCTTTGGGG ACCGCAATGA ATACGGATCT 
CGGGTTGGCG GAGGCATCGA TGTGCCTGTA CCCCGGCATT CGGTTGGTGT GGTCATTGGC 
CGGAGTGGAG AGATGATCAA GAAGATCCAG AATGATGCTG GTGTGCGCAT CCAGTTCAAG 
CAAGATGACG GGACCGGCCC TGAGAAGATT GCTCACATCA TGGGGCCTCC AGATCGGTGT 
GAGCATGCAG CCCGGATCAT CAATGACCTC CTCCAGAGTC TTCGGAGTGG GCCCCCAGGT 
CCTCCAGGGG CCCCTGGCAT GCCCCCTGGA GGCCGGGGCC GGGGCCGAGG CCAAGGCAAC 
TGGGGCCCTC CTGGAGGGGA GATGACTTTC TCCATTCCTA CCCATAAATG TGGGCTGGTC 
ATTGGCCGAG GTGGGGAGAA CGTGAAGGCC ATTAACCAGC AGACAGGCGC CTTTGTGGAA 
ATATCTCGGC AGCTGCCGCC CAATGGAGAC CCCAATTTCA AGTTATTTGT CATCCGGGGC 
TCACCTCAGC AGATTGACCA TGCAAAGCAG CTCATTGAGG AGAAGATAGA GGGTCCCCTC 
TGCCCAGTTG GACCAGGCCC TGGGGGACCA GGCCCTGCTG GACCCATGGG GCCTTTCCAC 
CCTGGACCCT TCAACCAGGG GCCTCCAGGG GCACCACCAC ATGCTGGTGG TCCCCCTCCT 
CACCAGTACC CGCCTCAGGG CTGGGGCAAT ACCTACCCCG AGTGGCAACC ACCTGCCCCT 
CATGACCCAA ACAAAGCTGC AGCAGCAGCT ACAGACCCTA ATGCTGCCTG GGCCGCCTAC 
TACTCCCACT ACTACCAGCA ACCCCCAGGC CCCGTGCCAG GCCCTGCCCC AGCCCCTGCA 
GCCCCACCTG CGCAAGGGGA GCCCCCCCAG CCTCCACCTA CTGGCCAATC AGACTATACC 
AAGGCTTGGG AAGAGTATTA CAAAAAAATT GGCCAGCAGC CCCAGCAGCC TGGGGCGCCC 
CCACAGCAGG ATTACACCAA GGCCTGGGAG GAGTACTACA AGAAGCAAGC ACAAGTGGCC 
ACTGGTGGGG GTCCTGGAGC ACCCCCTGGC TCCCAGCCTG ACTACAGTGC CGCCTGGGCT 
GAGTATTACA GACAGCAGGC TGCTTACTAC GGACAGACCC CAGGCCCTGG TGGCCCACAG 
CCACCTTCCA CCCAGCAGGG ACAGCAGCAG GCAACTGAAG CAAATGGATA TGAACTTCAT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Khsrp ( XM_006244292.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006244354.1 Rattus norvegicus KH-type splicing regulatory protein (Khsrp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa31870
Clone ID Related Accession (Same CDS sequence)	XM_006244292.3
Accession Version	XM_006244292.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	far upstream element-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006244292.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGACT ACAGCACCGG AGGTCCCCCG CCCGGCCCGC CGCCTCCCGC TGGCGGAGGA 
GGAGGAGCCG CGGGTGCGGG AGGAGGCCCT CCGCCGGGCC CGCCGGGTGC GGGAGACCGG 
GGCGGCGGAG GCCCTGGCGG CGGCGGCCCG GGTGGAGGAG GCGCGTCCGG GGGCCCTTCG 
CAGCCTCCGG GTGGCGGCGG TCCGGGGATA CGCAAGGACG CCTTCGCCGA CGCCGTGCAG 
CGGGCCCGCC AGATTGCAGC CAAAATCGGA GGTGATGCTG CTACCACCGT GAATAACAAC 
ACTCCTGATT TCGGTTTTGG GGGCCAAAAG AGACAGCTGG AAGATGGAGA CCAGCCAGAC 
AGCAAGAAAC TGGCTTCCCA GGGAGATTCA ATTGGTTCTC AGCTGGGACC CATCCATCCT 
CCCCCCAGGA CCTCAATGAC AGAAGAGTAT AGGGTTCCGG ACGGCATGGT GGGCTTGATC 
ATTGGCAGAG GTGGTGAGCA GATAAACAAA ATCCAGCAGG ACTCAGGCTG CAAAGTTCAG 
ATCTCACCAG ATAGTGGCGG CCTCCCTGAG CGCAGTGTGT CCCTGACTGG AGCACCAGAG 
TCTGTCCAAA AGGCAAAGAT GATGCTGGAT GACATTGTGT CTCGGGGCCG TGGAGGCCCC 
CCAGGACAGT TCCATGACAA CGCCAACGGG GGTCAGAATG GCACAGTGCA GGAGATCATG 
ATCCCTGCTG GCAAGGCTGG CCTGGTCATT GGCAAGGGTG GAGAGACCAT CAAGCAGCTG 
CAGGAGCGGG CTGGGGTGAA GATGATTTTA ATTCAGGACG GCTCCCAGAA CACAAATGTG 
GACAAGCCGC TGCGGATTAT TGGGGACCCA TACAAAGTAC AGCAAGCCTG TGAGATGGTG 
ATGGACATCC TGCGAGAACG TGACCAGGGT GGCTTTGGGG ACCGCAATGA ATACGGATCT 
CGGGTTGGCG GAGGCATCGA TGTGCCTGTA CCCCGGCATT CGGTTGGTGT GGTCATTGGC 
CGGAGTGGAG AGATGATCAA GAAGATCCAG AATGATGCTG GTGTGCGCAT CCAGTTCAAG 
CAAGATGACG GGACCGGCCC TGAGAAGATT GCTCACATCA TGGGGCCTCC AGATCGGTGT 
GAGCATGCAG CCCGGATCAT CAATGACCTC CTCCAGAGTC TTCGGAGTGG GCCCCCAGGT 
CCTCCAGGGG CCCCTGGCAT GCCCCCTGGA GGCCGGGGCC GGGGCCGAGG CCAAGGCAAC 
TGGGGCCCTC CTGGAGGGGA GATGACTTTC TCCATTCCTA CCCATAAATG TGGGCTGGTC 
ATTGGCCGAG GTGGGGAGAA CGTGAAGGCC ATTAACCAGC AGACAGGCGC CTTTGTGGAA 
ATATCTCGGC AGCTGCCGCC CAATGGAGAC CCCAATTTCA AGTTATTTGT CATCCGGGGC 
TCACCTCAGC AGATTGACCA TGCAAAGCAG CTCATTGAGG AGAAGATAGA GGGTCCCCTC 
TGCCCAGTTG GACCAGGCCC TGGGGGACCA GGCCCTGCTG GACCCATGGG GCCTTTCAAC 
CCTGGACCCT TCAACCAGGG GCCTCCAGGG GCACCACCAC ATGCTGGTGG TCCCCCTCCT 
CACCAGTACC CGCCTCAGGG CTGGGGCAAT ACCTACCCCC AGTGGCAACC ACCTGCCCCT 
CATGACCCAA ACAAAGCTGC AGCAGCAGCT ACAGACCCTA ATGCTGCCTG GGCCGCCTAC 
TACTCCCACT ACTACCAGCA ACCCCCAGGC CCCGTGCCAG GCCCTGCCCC AGCCCCTGCA 
GCCCCACCTG CGCAAGGGGA GCCCCCCCAG CCTCCACCTA CTGGCCAATC AGACTATACC 
AAGGCTTGGG AAGAGTATTA CAAAAAAATT GGCCAGCAGC CCCAGCAGCC TGGGGCGCCC 
CCACAGCAGG ATTACACCAA GGCCTGGGAG GAGTACTACA AGAAGCAAGC ACAAGTGGCC 
ACTGGTGGGG GTCCTGGAGC ACCCCCTGGC TCCCAGCCTG ACTACAGTGC CGCCTGGGCT 
GAGTATTACA GACAGCAGGC TGCTTACTAC GGACAGACCC CAGGCCCTGG TGGCCCACAG 
CCACCTCCCA CCCAGCAGGG ACAGCAGCAG GCAAGTGGGA ACTGCCACCC TCCTCCTCCT 
CCTTTCTCCT TCCAACCCCC GGCCACCGTC CATCCTGCCT TAGTGGGTAG CGCCGGAAAC 
CCTTTCCCCT GCGGGGTGTG CCCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006244354.1
CDS	136..2382
Translation	MSDYSTGGPPPGPPPPAGGGGGAAGAGGGPPPGPPGAGDRGGGGPGGGGPGGGGASGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNNTPDFGFGGQKRQLEDGDQPDSKKLASQGDSIGSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRVGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGAPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFVIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPNKAAAAATDPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNCHPPPPPFSFQPPATVHPALVGSAGNPFPCGVCP

Target ORF information:

RefSeq Version	XM_006244292.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KH-type splicing regulatory protein (Khsrp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006244292.3

ORF Insert Sequence:

ATGTCGGACT ACAGCACCGG AGGTCCCCCG CCCGGCCCGC CGCCTCCCGC TGGCGGAGGA 
GGAGGAGCCG CGGGTGCGGG AGGAGGCCCT CCGCCGGGCC CGCCGGGTGC GGGAGACCGG 
GGCGGCGGAG GCCCTGGCGG CGGCGGCCCG GGTGGAGGAG GCGCGTCCGG GGGCCCTTCG 
CAGCCTCCGG GTGGCGGCGG TCCGGGGATA CGCAAGGACG CCTTCGCCGA CGCCGTGCAG 
CGGGCCCGCC AGATTGCAGC CAAAATCGGA GGTGATGCTG CTACCACCGT GAATAACAAC 
ACTCCTGATT TCGGTTTTGG GGGCCAAAAG AGACAGCTGG AAGATGGAGA CCAGCCAGAC 
AGCAAGAAAC TGGCTTCCCA GGGAGATTCA ATTGGTTCTC AGCTGGGACC CATCCATCCT 
CCCCCCAGGA CCTCAATGAC AGAAGAGTAT AGGGTTCCGG ACGGCATGGT GGGCTTGATC 
ATTGGCAGAG GTGGTGAGCA GATAAACAAA ATCCAGCAGG ACTCAGGCTG CAAAGTTCAG 
ATCTCACCAG ATAGTGGCGG CCTCCCTGAG CGCAGTGTGT CCCTGACTGG AGCACCAGAG 
TCTGTCCAAA AGGCAAAGAT GATGCTGGAT GACATTGTGT CTCGGGGCCG TGGAGGCCCC 
CCAGGACAGT TCCATGACAA CGCCAACGGG GGTCAGAATG GCACAGTGCA GGAGATCATG 
ATCCCTGCTG GCAAGGCTGG CCTGGTCATT GGCAAGGGTG GAGAGACCAT CAAGCAGCTG 
CAGGAGCGGG CTGGGGTGAA GATGATTTTA ATTCAGGACG GCTCCCAGAA CACAAATGTG 
GACAAGCCGC TGCGGATTAT TGGGGACCCA TACAAAGTAC AGCAAGCCTG TGAGATGGTG 
ATGGACATCC TGCGAGAACG TGACCAGGGT GGCTTTGGGG ACCGCAATGA ATACGGATCT 
CGGGTTGGCG GAGGCATCGA TGTGCCTGTA CCCCGGCATT CGGTTGGTGT GGTCATTGGC 
CGGAGTGGAG AGATGATCAA GAAGATCCAG AATGATGCTG GTGTGCGCAT CCAGTTCAAG 
CAAGATGACG GGACCGGCCC TGAGAAGATT GCTCACATCA TGGGGCCTCC AGATCGGTGT 
GAGCATGCAG CCCGGATCAT CAATGACCTC CTCCAGAGTC TTCGGAGTGG GCCCCCAGGT 
CCTCCAGGGG CCCCTGGCAT GCCCCCTGGA GGCCGGGGCC GGGGCCGAGG CCAAGGCAAC 
TGGGGCCCTC CTGGAGGGGA GATGACTTTC TCCATTCCTA CCCATAAATG TGGGCTGGTC 
ATTGGCCGAG GTGGGGAGAA CGTGAAGGCC ATTAACCAGC AGACAGGCGC CTTTGTGGAA 
ATATCTCGGC AGCTGCCGCC CAATGGAGAC CCCAATTTCA AGTTATTTGT CATCCGGGGC 
TCACCTCAGC AGATTGACCA TGCAAAGCAG CTCATTGAGG AGAAGATAGA GGGTCCCCTC 
TGCCCAGTTG GACCAGGCCC TGGGGGACCA GGCCCTGCTG GACCCATGGG GCCTTTCAAC 
CCTGGACCCT TCAACCAGGG GCCTCCAGGG GCACCACCAC ATGCTGGTGG TCCCCCTCCT 
CACCAGTACC CGCCTCAGGG CTGGGGCAAT ACCTACCCCC AGTGGCAACC ACCTGCCCCT 
CATGACCCAA ACAAAGCTGC AGCAGCAGCT ACAGACCCTA ATGCTGCCTG GGCCGCCTAC 
TACTCCCACT ACTACCAGCA ACCCCCAGGC CCCGTGCCAG GCCCTGCCCC AGCCCCTGCA 
GCCCCACCTG CGCAAGGGGA GCCCCCCCAG CCTCCACCTA CTGGCCAATC AGACTATACC 
AAGGCTTGGG AAGAGTATTA CAAAAAAATT GGCCAGCAGC CCCAGCAGCC TGGGGCGCCC 
CCACAGCAGG ATTACACCAA GGCCTGGGAG GAGTACTACA AGAAGCAAGC ACAAGTGGCC 
ACTGGTGGGG GTCCTGGAGC ACCCCCTGGC TCCCAGCCTG ACTACAGTGC CGCCTGGGCT 
GAGTATTACA GACAGCAGGC TGCTTACTAC GGACAGACCC CAGGCCCTGG TGGCCCACAG 
CCACCTCCCA CCCAGCAGGG ACAGCAGCAG GCAAGTGGGA ACTGCCACCC TCCTCCTCCT 
CCTTTCTCCT TCCAACCCCC GGCCACCGTC CATCCTGCCT TAGTGGGTAG CGCCGGAAAC 
CCTTTCCCCT GCGGGGTGTG CCCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
Biochimica et biophysica acta1859(10)1299-305(2016 10)
Connerty P,Bajan S,Remenyi J,Fuller-Pace FV,Hutvagner G

microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator.
Atherosclerosis243(2)523-32(2015 Dec)
Jiang H,Zhang J,Du Y,Jia X,Yang F,Si S,Wang L,Hong B

Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.
The international journal of biochemistry & cell biology481-10(2014 Mar)
Zhu X,Yao L,Yang X,Sun H,Guo A,Li A,Yang H

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.
PloS one8(11)e79255(2013)
Bird CW,Gardiner AS,Bolognani F,Tanner DC,Chen CY,Lin WJ,Yoo S,Twiss JL,Perrone-Bizzozero N

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.
PLoS genetics8(7)e1002823(2012)
Repetto E,Briata P,Kuziner N,Harfe BD,McManus MT,Gherzi R,Rosenfeld MG,Trabucchi M

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Khsrp cDNA ORF clone, Rattus norvegicus(Norway rat)

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