Erp29 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Erp29
Entrez Gene ID	117030
Full Name	endoplasmic reticulum protein 29
General protein information	Preferred Names endoplasmic reticulum protein 29 Names endoplasmic reticulum resident protein 29 ERp31 endoplasmic reticulum protein ERp29 endoplasmic reticulum resident protein 31 endoplasmic retuclum protein 29
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16
Summary	may play a role in folding or secretion of thyroglobulin [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053961.2	NP_446413.1	endoplasmic reticulum resident protein 29 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ERP29	NP_001069739.1
Pan troglodytes (chimpanzee)	ERP29	XP_001139225.2
	ERP29	XP_001109649.1
Canis lupus familiaris (dog)	ERP29	XP_005636567.1
Rattus norvegicus (Norway rat)	Erp29	NP_446413.1
Drosophila melanogaster (fruit fly)	wbl	NP_725867.1
Xenopus tropicalis (tropical clawed frog)	erp29	XP_002940171.2
Homo sapiens (human)	ERP29	NP_006808.1
Mus musculus (house mouse)	Erp29	NP_080405.1
Gallus gallus (chicken)	ERP29	NP_001263253.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000395	XP_310706.3

Gene Ontology
Bibliography

Related articles in PubMed

Endoplasmic Reticulum Protein 29 Protects Axotomized Neurons from Apoptosis and Promotes Neuronal Regeneration Associated with Erk Signal.
Zhang YH, Belegu V, Zou Y, Wang F, Qian BJ, Liu R, Dai P, Zhao W, Gao FB, Wang L, Cao LM, McDonald JW, Liu S, Lin N, Wang TH
Molecular neurobiology52(1)522-32(2015 Aug)

Endoplasmic reticulum protein 29 protects cortical neurons from apoptosis and promoting corticospinal tract regeneration to improve neural behavior via caspase and Erk signal in rats with spinal cord transection.
Liu R, Zhao W, Zhao Q, Liu SJ, Liu J, He M, Xu Y, Wang W, Liu W, Xia QJ, Li CY, Wang TH
Molecular neurobiology50(3)1035-48(2014 Dec)

ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response.
Hirsch I, Weiwad M, Prell E, Ferrari DM
Apoptosis : an international journal on programmed cell death19(5)801-15(2014 May)

Endoplasmic reticulum protein (ERp) 29 binds as strongly as protein disulfide isomerase (PDI) to bisphenol A.
Miyake Y, Hashimoto S, Sasaki Y, Kudo T, Oguro A, Imaoka S
Chemical research in toxicology27(4)501-6(2014 Apr)

An interaction map of endoplasmic reticulum chaperones and foldases.
Jansen G, M??tt?nen P, Denisov AY, Scarffe L, Schade B, Balghi H, Dejgaard K, Chen LY, Muller WJ, Gehring K, Thomas DY
Molecular & cellular proteomics : MCP11(9)710-23(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

overexpression of ERp29 in cortical neurons after axotomy increased expression of Erk-1 and PI3K while decreasing the expression of caspase-3 expression.
Title: Endoplasmic Reticulum Protein 29 Protects Axotomized Neurons from Apoptosis and Promotes Neuronal Regeneration Associated with Erk Signal.

ERp29 can improve locomotor function by promoting neuronal survival and axonal regeneration in spinal cord transection rats via caspase and Erk signal pathway.
Title: Endoplasmic reticulum protein 29 protects cortical neurons from apoptosis and promoting corticospinal tract regeneration to improve neural behavior via caspase and Erk signal in rats with spinal cord transection.

ERp29 was first identified as a BPA-binding protein but is not involved in the T3 response of GH3 cells
Title: Endoplasmic reticulum protein (ERp) 29 binds as strongly as protein disulfide isomerase (PDI) to bisphenol A.

This supports a new role for ERp29 as a chaperone that helps stabilize monomeric Cx43 to enable oligomerization to occur in the Golgi apparatus.
Title: ERp29 restricts Connexin43 oligomerization in the endoplasmic reticulum.

lactating mammary glands were expressing ERp29 while the resting glands did not
Title: ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts.

The following Erp29 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Erp29 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11187	NM_053961.2 Latest version!	Rattus norvegicus endoplasmic reticulum protein 29 (Erp29), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Erp29 ( NM_053961.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446413.1 Rattus norvegicus endoplasmic reticulum protein 29 (Erp29), mRNA.

Price & Availability↑

CloneID	ORa11187
Clone ID Related Accession (Same CDS sequence)	NM_053961.2
Accession Version	NM_053961.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	endoplasmic reticulum resident protein 29 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091129.1. On Jun 10, 2007 this sequence version replaced NM_053961.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC091129.1, U36482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCCG CCGTTCCTGG CGCCGTTTCG CTCTCCCCAC TGCTGTCCGT TCTCCTTGGC 
CTGCTGCTCC TCTCTGCTCC TCATGGCGCC AGCGGCCTGC ACACGAAGGG CGCCCTTCCC 
TTGGACACAG TCACTTTCTA CAAGGTCATT CCCAAAAGCA AGTTCGTCTT GGTGAAGTTC 
GACACCCAGT ACCCCTATGG AGAGAAGCAA GATGAGTTTA AGCGTCTGGC TGAGAACTCA 
GCCTCCAGCG ATGATCTCTT GGTGGCAGAG GTGGGGATCT CAGACTATGG TGACAAGCTG 
AACATGGAGC TGAGTGAGAA GTACAAGCTG GACAAAGAGA GCTACCCAGT CTTCTACCTC 
TTCCGGGATG GGGACTTTGA GAATCCTGTC CCATACAGCG GGGCAGTTAA AGTTGGAGCC 
ATCCAGCGCT GGCTCAAGGG GCAGGGAGTC TATCTGGGCA TGCCTGGATG TCTGCCTGCG 
TACGATGCCC TGGCGGGCCA GTTCATCGAG GCCTCCAGCA GAGAGGCCCG CCAGGCCATC 
CTGAAACAGG GGCAGGATGG CCTCTCAGGT GTGAAGGAGA CAGACAAGAA GTGGGCCAGT 
CAGTACCTGA AGATCATGGG GAAGATCTTG GACCAAGGTG AAGACTTCCC GGCCTCCGAG 
CTGGCCCGGA TCAGTAAGCT CATTGAGAAC AAGATGAGTG AGGGTAAGAA GGAAGAGCTG 
CAGAGGAGCC TCAACATCCT CACCGCCTTC CGCAAGAAAG GCGCCGAGAA GGAGGAGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446413.1
CDS	16..798
Translation	MAAAVPGAVSLSPLLSVLLGLLLLSAPHGASGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYSGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGQFIEASSREARQAILKQGQDGLSGVKETDKKWASQYLKIMGKILDQGEDFPASELARISKLIENKMSEGKKEELQRSLNILTAFRKKGAEKEEL

Target ORF information:

RefSeq Version	NM_053961.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endoplasmic reticulum protein 29 (Erp29), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053961.2

ORF Insert Sequence:

ATGGCTGCCG CCGTTCCTGG CGCCGTTTCG CTCTCCCCAC TGCTGTCCGT TCTCCTTGGC 
CTGCTGCTCC TCTCTGCTCC TCATGGCGCC AGCGGCCTGC ACACGAAGGG CGCCCTTCCC 
TTGGACACAG TCACTTTCTA CAAGGTCATT CCCAAAAGCA AGTTCGTCTT GGTGAAGTTC 
GACACCCAGT ACCCCTATGG AGAGAAGCAA GATGAGTTTA AGCGTCTGGC TGAGAACTCA 
GCCTCCAGCG ATGATCTCTT GGTGGCAGAG GTGGGGATCT CAGACTATGG TGACAAGCTG 
AACATGGAGC TGAGTGAGAA GTACAAGCTG GACAAAGAGA GCTACCCAGT CTTCTACCTC 
TTCCGGGATG GGGACTTTGA GAATCCTGTC CCATACAGCG GGGCAGTTAA AGTTGGAGCC 
ATCCAGCGCT GGCTCAAGGG GCAGGGAGTC TATCTGGGCA TGCCTGGATG TCTGCCTGCG 
TACGATGCCC TGGCGGGCCA GTTCATCGAG GCCTCCAGCA GAGAGGCCCG CCAGGCCATC 
CTGAAACAGG GGCAGGATGG CCTCTCAGGT GTGAAGGAGA CAGACAAGAA GTGGGCCAGT 
CAGTACCTGA AGATCATGGG GAAGATCTTG GACCAAGGTG AAGACTTCCC GGCCTCCGAG 
CTGGCCCGGA TCAGTAAGCT CATTGAGAAC AAGATGAGTG AGGGTAAGAA GGAAGAGCTG 
CAGAGGAGCC TCAACATCCT CACCGCCTTC CGCAAGAAAG GCGCCGAGAA GGAGGAGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Endoplasmic Reticulum Protein 29 Protects Axotomized Neurons from Apoptosis and Promotes Neuronal Regeneration Associated with Erk Signal.
Molecular neurobiology52(1)522-32(2015 Aug)
Zhang YH,Belegu V,Zou Y,Wang F,Qian BJ,Liu R,Dai P,Zhao W,Gao FB,Wang L,Cao LM,McDonald JW,Liu S,Lin N,Wang TH

Endoplasmic reticulum protein 29 protects cortical neurons from apoptosis and promoting corticospinal tract regeneration to improve neural behavior via caspase and Erk signal in rats with spinal cord transection.
Molecular neurobiology50(3)1035-48(2014 Dec)
Liu R,Zhao W,Zhao Q,Liu SJ,Liu J,He M,Xu Y,Wang W,Liu W,Xia QJ,Li CY,Wang TH

ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response.
Apoptosis : an international journal on programmed cell death19(5)801-15(2014 May)
Hirsch I,Weiwad M,Prell E,Ferrari DM

Endoplasmic reticulum protein (ERp) 29 binds as strongly as protein disulfide isomerase (PDI) to bisphenol A.
Chemical research in toxicology27(4)501-6(2014 Apr)
Miyake Y,Hashimoto S,Sasaki Y,Kudo T,Oguro A,Imaoka S

An interaction map of endoplasmic reticulum chaperones and foldases.
Molecular & cellular proteomics : MCP11(9)710-23(2012 Sep)
Jansen G,M??tt?nen P,Denisov AY,Scarffe L,Schade B,Balghi H,Dejgaard K,Chen LY,Muller WJ,Gehring K,Thomas DY

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Erp29 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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