The following PCSK9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCSK9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OPc00225 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001111122.1 | |
| Accession Version | NM_001111122.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Pan troglodytes(chimpanzee) | |
| Product | proprotein convertase subtilisin/kexin type 9 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF692497.1. On or before Dec 9, 2007 this sequence version replaced XM_513430.2, XM_001154126.1. ##Evidence-Data-START## Transcript exon combination :: EF692497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01120800, SAMN01120804 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGCACCG TCAGCTCCAG GCGGTCCTGG TGGCCGCTGC CACTGCTGCT GCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001104592.1 |
| CDS | 1..2079 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001111122.1 |
1 | ATGGGCACCG TCAGCTCCAG GCGGTCCTGG TGGCCGCTGC CACTGCTGCT GCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OPc58091 | |
| Clone ID Related Accession (Same CDS sequence) | XM_016953243.1 | |
| Accession Version | XM_016953243.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-01 | |
| Organism | Pan troglodytes(chimpanzee) | |
| Product | proprotein convertase subtilisin/kexin type 9 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006468.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_016808732.1 |
| CDS | 137..2269 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_016953243.1 |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OPc91983 | |
| Clone ID Related Accession (Same CDS sequence) | XM_024347585.1 | |
| Accession Version | XM_024347585.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2361bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-03-19 | |
| Organism | Pan troglodytes(chimpanzee) | |
| Product | proprotein convertase subtilisin/kexin type 9 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036879.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_024203353.1 |
| CDS | 151..2511 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_024347585.1 |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OPc91984 | |
| Clone ID Related Accession (Same CDS sequence) | XM_016953243.2 | |
| Accession Version | XM_016953243.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-03-19 | |
| Organism | Pan troglodytes(chimpanzee) | |
| Product | proprotein convertase subtilisin/kexin type 9 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036879.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_016953243.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_016808732.2 |
| CDS | 107..2233 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_016953243.2 |
1 | ATGGGGCTCT GGTGGCGTGA TCTGCGCGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate species. |
