ESR2 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	ESR2
Entrez Gene ID	443066
Full Name	estrogen receptor 2
Synonyms	ERB,ERBETA
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
XM_012180599.2	XP_012035989.1	estrogen receptor beta isoform X1
XM_012180602.2	XP_012035992.1	estrogen receptor beta isoform X2
NM_001009737.1	NP_001009737.1	estrogen receptor beta
XM_015096686.1	XP_014952172.1	estrogen receptor beta isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells.
Pastore MB, Talwar S, Conley MR, Magness RR
Biology of reproduction94(6)139(2016 06)

Ontogeny of estrogen receptor alpha, estrogen receptor beta and androgen receptor, and their co-localization with Islet-1 in the dorsal root ganglia of sheep fetuses during gestation.
Luo H, Liu J, Kang D, Cui S
Histochemistry and cell biology129(4)525-33(2008 Apr)

Cerebral hypoperfusion increases estrogen receptor abundance in the ovine fetal brain and pituitary.
Wood CE
Neuroendocrinology87(4)216-22(2008)

Differential modulation of gonadotropin secretion by selective estrogen receptor 1 and estrogen receptor 2 agonists in ovariectomized ewes.
Arreguin-Arevalo JA, Davis TL, Nett TM
Biology of reproduction77(2)320-8(2007 Aug)

Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study.
Song D, Liu G, Luu-The V, Zhao D, Wang L, Zhang H, Xueling G, Li S, D?sy L, Labrie F, Pelletier G
The Journal of steroid biochemistry and molecular biology101(2-3)136-44(2006 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In uterine artery endothelial cells: 1) eNOS phosphorylation changes occur via ER-alpha- and ER-beta-dependent mechanisms and 2) ER-alpha and ER-beta can both increase NO levels independently from each other.
Title: Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells.

Ontogeny of ERB and its co-localization with Islet-1 in the dorsal root ganglia of sheep fetuses during gestation is reported.
Title: Ontogeny of estrogen receptor alpha, estrogen receptor beta and androgen receptor, and their co-localization with Islet-1 in the dorsal root ganglia of sheep fetuses during gestation.

The expression of ER-alpha and ER-beta in the brain and pituitary of fetal sheep are influenced by circulating estrogen concentrations and acutely regulated in response to cerebral hypoperfusion.
Title: Cerebral hypoperfusion increases estrogen receptor abundance in the ovine fetal brain and pituitary.

estrogen receptor 1 and 2(ESR1 and ESR2) mediate feedback of estradiol(E2) on secretion of LH
Title: Differential modulation of gonadotropin secretion by selective estrogen receptor 1 and estrogen receptor 2 agonists in ovariectomized ewes.

Moreover, the high expression of both 17beta-HSD type 12 and ERbeta in breast carcinoma cells may play a role in the development and/or progression of breast cancer.
Title: Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study.

The following ESR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ESR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OSm00089	NM_001009737.1 Latest version!	Ovis aries estrogen receptor 2 (ESR2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OSm21611	XM_015096686.1 Latest version!	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OSm21611	XM_012180599.2 Latest version!	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OSm21612	XM_012180602.2 Latest version!	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ESR2 ( NM_001009737.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001009737.1 Ovis aries estrogen receptor 2 (ESR2), mRNA.

Price & Availability↑

CloneID	OSm00089
Clone ID Related Accession (Same CDS sequence)	NM_001009737.1
Accession Version	NM_001009737.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Ovis aries(sheep)
Product	estrogen receptor beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF177936.1. ##Evidence-Data-START## Transcript exon combination :: AF177936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104495056 [ECO:0000348] ##Evidence-Data-END##

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACTCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAT CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009737.1
CDS	1..1584
Translation	MDVKNSPSSLNSPVSYNCGQSILPLEPGPIYLPSSYVESRHEYSAVTFYSPAVMNYSIPNNSEDGPGRQTTSPNVLWPTPGHLSPLAIHCQSSLLYAEPQKSPWCETRSLEHTFPVNRETLKRKASGSSCASPVSSPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRNSDEQLHCLSKTKRNGAPMTRVKELLLSALSPEQLVLTLLEAEPPHVLMSRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSATASQEADSGRKLTHLLNAVTDALVWVIAKSGMSSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHTLRSNKPLVTRSERNLAEDSESKEGSQKPQAQ

Target ORF information:

RefSeq Version	NM_001009737.1
Organism	Ovis aries(sheep)
Definition	Ovis aries estrogen receptor 2 (ESR2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009737.1

ORF Insert Sequence:

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACTCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAT CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ESR2 ( XM_012180599.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_012035989.1 Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSm21611
Clone ID Related Accession (Same CDS sequence)	XM_012180599.2 , XM_015096686.1
Accession Version	XM_012180599.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	estrogen receptor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639016.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012180599.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACGCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAC CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_012035989.1
CDS	434..2017
Translation	MDVKNSPSSLNSPVSYNCGQSILPLEPGPIYLPSSYVESRHEYSAVTFYSPAVMNYSIPNNSEDGPGRQTTSPNVLWPTPGHLSPLAIHCQSSLLYAEPQKSPWCETRSLEHTFPVNRETLKRKASGSSCASPVSSPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRNSDEQLHCLSKTKRNGAPMTRVKELLLSALSPEQLVLTLLEAEPPHVLMSRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSATAPQEADSGRKLTHLLNAVTDALVWVIAKSGMSSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHTLRSNKPLVTRSERNLAEDSESKEGSQKPQAQ

Target ORF information:

RefSeq Version	XM_012180599.2
Organism	Ovis aries(sheep)
Definition	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012180599.2

ORF Insert Sequence:

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACGCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAC CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ESR2 ( XM_015096686.1 ) cDNA ORF clone, Ovis aries(sheep) -> XP_014952172.1 Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OSm21611
Clone ID Related Accession (Same CDS sequence)	XM_012180599.2 , XM_015096686.1
Accession Version	XM_015096686.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	estrogen receptor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639016.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACGCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAC CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014952172.1
CDS	2205..3788
Translation	MDVKNSPSSLNSPVSYNCGQSILPLEPGPIYLPSSYVESRHEYSAVTFYSPAVMNYSIPNNSEDGPGRQTTSPNVLWPTPGHLSPLAIHCQSSLLYAEPQKSPWCETRSLEHTFPVNRETLKRKASGSSCASPVSSPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRNSDEQLHCLSKTKRNGAPMTRVKELLLSALSPEQLVLTLLEAEPPHVLMSRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSATAPQEADSGRKLTHLLNAVTDALVWVIAKSGMSSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHTLRSNKPLVTRSERNLAEDSESKEGSQKPQAQ

Target ORF information:

RefSeq Version	XM_015096686.1
Organism	Ovis aries(sheep)
Definition	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015096686.1

ORF Insert Sequence:

ATGGATGTCA AAAACTCACC ATCTAGCCTT AACTCTCCTG TCTCCTATAA CTGCGGTCAA 
TCCATTCTAC CCCTGGAGCC AGGCCCCATA TATTTACCCT CTTCCTATGT AGAGAGCCGC 
CATGAATACT CAGCCGTGAC ATTCTATAGC CCTGCTGTGA TGAATTACAG TATTCCCAAT 
AACTCAGAAG ATGGGCCTGG TCGACAGACC ACAAGCCCAA ATGTATTGTG GCCAACTCCT 
GGACACCTCT CTCCTTTAGC CATCCATTGC CAGTCGTCAC TTCTGTATGC AGAACCTCAA 
AAGAGTCCTT GGTGTGAAAC CAGATCATTA GAACACACCT TCCCTGTGAA CAGGGAGACA 
TTGAAAAGGA AAGCTAGTGG GAGCAGTTGT GCCAGCCCTG TTTCTAGTCC GAGTTCAAAG 
AGGGATGCCC ACTTCTGTGC TGTCTGCAGC GATTATGCGT CGGGATATCA CTATGGAGTC 
TGGTCATGTG AAGGATGTAA GGCCTTTTTT AAAAGAAGCA TTCAAGGACA TAATGATTAT 
ATTTGTCCAG CTACAAATCA GTGTACCATA GATAAGAACC GACGTAAAAG CTGTCAGGCC 
TGTCGACTGC GGAAGTGCTA TGAGGTCGGA ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG 
TGTGGGTACC GCATAGTGCG AAGGCAGAGA AATTCTGATG AGCAGCTGCA CTGCCTGAGC 
AAAACCAAGA GGAACGGTGC ACCCATGACC CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG 
AGCCCAGAGC AGCTGGTGCT TACGCTCCTG GAGGCCGAGC CGCCCCACGT GCTCATGAGC 
CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC ATGATGATGT CCTTGACCAA GCTGGCCGAC 
AAGGAACTGG TACACATGAT CAGCTGGGCC AAGAAGATTC CGGGCTTCGT GGAGCTCAGC 
CTGTACGACC AAGTGCGGCT CTTGGAGAGC TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG 
ATGTGGCGCT CCATCGACCA CCCCGGCAAG CTCATCTTTG CTCCAGACCT CGTTCTGGAC 
AGGGATGAAG GGAAATGTGT TGAAGGAATT CTAGAAATCT TTGACATGCT CCTGGCAACG 
ACTTCAAGGT TTCGTGAGTT AAAACTCCAA CACAAAGAAT ATCTCTGTGT CAAGGCCATG 
ATCCTCCTCA ACTCCAGTAT GTACCCTTCA GCTACAGCAC CCCAGGAGGC TGACAGTGGC 
CGGAAGCTGA CTCACCTGCT GAATGCCGTG ACGGACGCTC TGGTCTGGGT GATTGCCAAG 
AGCGGCATGT CCTCCCAGCA ACAGTCCATG CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT 
CATGTCAGGC ATGCCAGTAA CAAGGGCATG GAACACCTGC TCAACATGAA GTGCAAAAAT 
GTGGTGCCCG TCTACGATCT GCTGCTGGAG ATGCTGAATG CCCACACGCT TCGCAGCAAC 
AAGCCTTTGG TCACAAGGTC TGAGCGCAAC CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC 
TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ESR2 ( XM_012180602.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_012035992.1 Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X3, mRNA.

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CloneID	OSm21612
Clone ID Related Accession (Same CDS sequence)	XM_012180602.2
Accession Version	XM_012180602.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	estrogen receptor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639016.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012180602.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG TGTGGGTACC GCATAGTGCG AAGGCAGAGA 
AATTCTGATG AGCAGCTGCA CTGCCTGAGC AAAACCAAGA GGAACGGTGC ACCCATGACC 
CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG AGCCCAGAGC AGCTGGTGCT TACGCTCCTG 
GAGGCCGAGC CGCCCCACGT GCTCATGAGC CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC 
ATGATGATGT CCTTGACCAA GCTGGCCGAC AAGGAACTGG TACACATGAT CAGCTGGGCC 
AAGAAGATTC CGGGCTTCGT GGAGCTCAGC CTGTACGACC AAGTGCGGCT CTTGGAGAGC 
TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG ATGTGGCGCT CCATCGACCA CCCCGGCAAG 
CTCATCTTTG CTCCAGACCT CGTTCTGGAC AGGGATGAAG GGAAATGTGT TGAAGGAATT 
CTAGAAATCT TTGACATGCT CCTGGCAACG ACTTCAAGGT TTCGTGAGTT AAAACTCCAA 
CACAAAGAAT ATCTCTGTGT CAAGGCCATG ATCCTCCTCA ACTCCAGTAT GTACCCTTCA 
GCTACAGCAC CCCAGGAGGC TGACAGTGGC CGGAAGCTGA CTCACCTGCT GAATGCCGTG 
ACGGACGCTC TGGTCTGGGT GATTGCCAAG AGCGGCATGT CCTCCCAGCA ACAGTCCATG 
CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT CATGTCAGGC ATGCCAGTAA CAAGGGCATG 
GAACACCTGC TCAACATGAA GTGCAAAAAT GTGGTGCCCG TCTACGATCT GCTGCTGGAG 
ATGCTGAATG CCCACACGCT TCGCAGCAAC AAGCCTTTGG TCACAAGGTC TGAGCGCAAC 
CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC TCCCAGAAAC CCCAGGCTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_012035992.1
CDS	454..1407
Translation	MVKCGSRRERCGYRIVRRQRNSDEQLHCLSKTKRNGAPMTRVKELLLSALSPEQLVLTLLEAEPPHVLMSRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSATAPQEADSGRKLTHLLNAVTDALVWVIAKSGMSSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHTLRSNKPLVTRSERNLAEDSESKEGSQKPQAQ

Target ORF information:

RefSeq Version	XM_012180602.2
Organism	Ovis aries(sheep)
Definition	Ovis aries estrogen receptor 2 (ER beta) (ESR2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012180602.2

ORF Insert Sequence:

ATGGTGAAGT GTGGCTCCCG GAGAGAAAGG TGTGGGTACC GCATAGTGCG AAGGCAGAGA 
AATTCTGATG AGCAGCTGCA CTGCCTGAGC AAAACCAAGA GGAACGGTGC ACCCATGACC 
CGAGTGAAGG AGCTGCTGCT GAGTGCCCTG AGCCCAGAGC AGCTGGTGCT TACGCTCCTG 
GAGGCCGAGC CGCCCCACGT GCTCATGAGC CGCCCCAGCG CGCCCTTCAC TGAGGCCTCC 
ATGATGATGT CCTTGACCAA GCTGGCCGAC AAGGAACTGG TACACATGAT CAGCTGGGCC 
AAGAAGATTC CGGGCTTCGT GGAGCTCAGC CTGTACGACC AAGTGCGGCT CTTGGAGAGC 
TGCTGGTTGG AGGTGCTCAT GGTGGGGCTG ATGTGGCGCT CCATCGACCA CCCCGGCAAG 
CTCATCTTTG CTCCAGACCT CGTTCTGGAC AGGGATGAAG GGAAATGTGT TGAAGGAATT 
CTAGAAATCT TTGACATGCT CCTGGCAACG ACTTCAAGGT TTCGTGAGTT AAAACTCCAA 
CACAAAGAAT ATCTCTGTGT CAAGGCCATG ATCCTCCTCA ACTCCAGTAT GTACCCTTCA 
GCTACAGCAC CCCAGGAGGC TGACAGTGGC CGGAAGCTGA CTCACCTGCT GAATGCCGTG 
ACGGACGCTC TGGTCTGGGT GATTGCCAAG AGCGGCATGT CCTCCCAGCA ACAGTCCATG 
CGCCTGGCTA ACCTGCTGAT GCTCCTGTCT CATGTCAGGC ATGCCAGTAA CAAGGGCATG 
GAACACCTGC TCAACATGAA GTGCAAAAAT GTGGTGCCCG TCTACGATCT GCTGCTGGAG 
ATGCTGAATG CCCACACGCT TCGCAGCAAC AAGCCTTTGG TCACAAGGTC TGAGCGCAAC 
CTGGCGGAGG ACAGTGAGAG CAAAGAGGGC TCCCAGAAAC CCCAGGCTCA GTGA