Gene Symbol | CHRNA7 |
Entrez Gene ID | 574230 |
Full Name | cholinergic receptor nicotinic alpha 7 subunit |
Synonyms | nica7 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » CHRNA7 cDNA ORF clone
Gene Symbol | CHRNA7 |
Entrez Gene ID | 574230 |
Full Name | cholinergic receptor nicotinic alpha 7 subunit |
Synonyms | nica7 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001032883.1 | NP_001028055.1 | neuronal acetylcholine receptor subunit alpha-7 precursor |
Mus musculus (house mouse) | Chrna7 | NP_031416.3 |
Rattus norvegicus (Norway rat) | Chrna7 | NP_036964.3 |
Drosophila melanogaster (fruit fly) | nAcRalpha-34E | NP_001246027.1 |
Caenorhabditis elegans (roundworm) | acr-16 | NP_505207.1 |
Caenorhabditis elegans (roundworm) | acr-25 | NP_001023570.2 |
Caenorhabditis elegans (roundworm) | acr-7 | NP_495647.1 |
Pan troglodytes (chimpanzee) | CHRNA7 | XP_001164138.1 |
CHRNA7 | NP_001028055.1 | |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008588 | XP_314691.2 |
Caenorhabditis elegans (roundworm) | acr-11 | NP_491906.1 |
Caenorhabditis elegans (roundworm) | acr-9 | NP_510285.2 |
Caenorhabditis elegans (roundworm) | acr-14 | NP_495716.1 |
Homo sapiens (human) | CHRNA7 | NP_000737.1 |
Bos taurus (cattle) | CHRNA7 | NP_776940.1 |
Gallus gallus (chicken) | CHRNA7 | NP_989512.2 |
Caenorhabditis elegans (roundworm) | acr-10 | NP_508692.2 |
Canis lupus familiaris (dog) | CHRNA7 | XP_545813.4 |
Danio rerio (zebrafish) | chrna7 | NP_957513.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100493611 | XP_002937717.2 |
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)
Nicotinic ?7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex.
Yang Y, Paspalas CD, Jin LE, Picciotto MR, Arnsten AF, Wang M
Proceedings of the National Academy of Sciences of the United States of America110(29)12078-83(2013 Jul)
The ly-6 protein, lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium.
Fu XW, Rekow SS, Spindel ER
American journal of physiology. Lung cellular and molecular physiology303(8)L661-8(2012 Oct)
Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells.
Fu XW, Lindstrom J, Spindel ER
American journal of respiratory cell and molecular biology41(1)93-9(2009 Jul)
Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells.
Proskocil BJ, Sekhon HS, Jia Y, Savchenko V, Blakely RD, Lindstrom J, Spindel ER
Endocrinology145(5)2498-506(2004 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Nicotinic alpha7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex.
Title: Nicotinic ?7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex.
Lynx1 appears to act as a negative modulator of alpha7 nAChR-induced events by inhibiting Src activation.
Title: The ly-6 protein, lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium.
Chronic nicotine exposure up-regulates nAChR activity in developing lung, and that nAChR activity can be further modified by tyrosine phosphorylation.
Title: Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells.
The following CHRNA7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHRNA7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb00438 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032883.1 | |
Accession Version | NM_001032883.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | neuronal acetylcholine receptor subunit alpha-7 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF486623.1. ##Evidence-Data-START## Transcript exon combination :: AF486623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688384 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCGCTGCT CGCAGGGAGG CGTCTGGCTG GCTCTGGCCG CGTCGCTCCT GCATGTGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001028055.1 |
CDS | 106..1614 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001032883.1 |
1 | ATGCGCTGCT CGCAGGGAGG CGTCTGGCTG GCTCTGGCCG CGTCGCTCCT GCATGTGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. |
Nicotinic ?7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. |
The ly-6 protein, lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium. |
Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells. |
Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. |