Lbr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lbr
Entrez Gene ID	98386
Full Name	lamin B receptor
Synonyms	AI505894,ic
General protein information	Preferred Names lamin B receptor Names lamin-B receptor ichthyosis integral nuclear envelope inner membrane protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H5\|1 84.89 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006497071.3	XP_006497134.1	lamin-B receptor isoform X1
XM_006497071.4	XP_006497134.1	delta(14)-sterol reductase isoform X1
XM_017313041.1	XP_017168530.1	delta(14)-sterol reductase isoform X1
NM_133815.2	NP_598576.2	delta(14)-sterol reductase LBR
XM_006497070.3	XP_006497133.1	lamin-B receptor isoform X1
XM_006497070.4	XP_006497133.1	delta(14)-sterol reductase isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	LBR	NP_919424.1
Pan troglodytes (chimpanzee)	LBR	XP_001137563.1
	LBR	XP_001094360.1
Bos taurus (cattle)	LBR	NP_001093799.1
Danio rerio (zebrafish)	lbr	NP_001002720.1
Drosophila melanogaster (fruit fly)	LBR	NP_726115.1
Schizosaccharomyces pombe (fission yeast)	erg24	NP_596767.1
Magnaporthe oryzae (rice blast fungus)	MGG_13986	XP_003716043.1
Mus musculus (house mouse)	Lbr	NP_598576.2
Eremothecium gossypii	AGOS_AFR346W	NP_985893.2
Canis lupus familiaris (dog)	LBR	XP_547512.2
Rattus norvegicus (Norway rat)	Lbr	NP_604448.1
Gallus gallus (chicken)	LBR	NP_990673.1
Saccharomyces cerevisiae (baker's yeast)	ERG24	NP_014119.1
Kluyveromyces lactis	KLLA0C12265g	XP_452744.1
Neurospora crassa	NCU08762	XP_956111.1

Gene Ontology
Bibliography

Related articles in PubMed

Accumulation of glycated proteins suggesting premature ageing in lamin B receptor deficient mice.
Hause F, Schlote D, Simm A, Hoffmann K, Santos AN
Biogerontology19(1)95-100(2018 Feb)

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Kurogi S, Sekimoto T, Funamoto T, Ota T, Nakamura S, Nagai T, Nakahara M, Yoshinobu K, Araki K, Araki M, Chosa E
Scientific reports740692(2017 Jan)

Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR).
Giannios I, Chatzantonaki E, Georgatos S
PloS one12(1)e0169626(2017)

Alterations in nuclear structure promote lupus autoimmunity in a mouse model.
Singh N, Johnstone DB, Martin KA, Tempera I, Kaplan MJ, Denny MF
Disease models & mechanisms9(8)885-97(2016 08)

Intrabody-mediated diverting of HP1? to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor.
Cardinale A, Filesi I, Singh PB, Biocca S
Experimental cell research338(1)70-81(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The diffusional mobility of full-length LBR shows significant regional variation along the nuclear envelope, consistent with the existence of discrete LBR microdomains and the occurrence of multiple, asymmetrically-spaced anastomoses along the nuclear envelope-endoplasmic reticulum interface. Native LBR may be "configured" by long-range interactions between adjacent transmembrane domains and parts of the NH2 region.
Title: Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR).

The N-terminal portion of LBR is probably responsible for the binding to HP1b.
Title: Intrabody-mediated diverting of HP1? to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor.

These results show a moderate skin differentiation phenotype, which indicates that upregulation of LBR is not the sole contributor to the Hutchinson-Gilford progeria syndrome phenotype.
Title: Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation.

Study identified LBR- and lamin-A/C-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C-dependent tether.
Title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.

sterol Delta(14) reductase domain of LBR plays a critical role in cholesterol biosynthesis and that this process is essential to both myeloid cell growth and functional maturation.
Title: Lamin B receptor regulates the growth and maturation of myeloid progenitors via its sterol reductase domain: implications for cholesterol biosynthesis in regulating myelopoiesis.

The following Lbr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lbr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10244	NM_133815.2 Latest version!	Mus musculus lamin B receptor (Lbr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu10244	XM_017313041.1 Latest version!	Mus musculus lamin B receptor (Lbr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu10244	XM_006497071.4 Latest version!	Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu10244	XM_006497070.4 Latest version!	Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu10244	XM_006497071.3	Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu10244	XM_006497070.3	Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lbr ( NM_133815.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598576.2 Mus musculus lamin B receptor (Lbr), mRNA.

Price & Availability↑

CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	NM_133815.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-10
Organism	Mus musculus(house mouse)
Product	delta(14)-sterol reductase LBR
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB849128.1, AK167157.1 and BE991506.1. On May 8, 2009 this sequence version replaced NM_133815.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK151798.1, AK088179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598576.2
CDS	129..2009
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	NM_133815.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133815.2

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lbr ( XM_006497071.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497134.1 Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	XM_006497071.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	lamin-B receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497071.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497134.1
CDS	211..2091
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	XM_006497071.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497071.3

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lbr ( XM_017313041.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168530.1 Mus musculus lamin B receptor (Lbr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	XM_017313041.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	delta(14)-sterol reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168530.1
CDS	121..2001
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	XM_017313041.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313041.1

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lbr ( XM_006497070.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497133.1 Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	XM_006497070.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	lamin-B receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497070.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497133.1
CDS	323..2203
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	XM_006497070.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497070.3

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lbr ( XM_006497071.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497134.1 Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	XM_006497071.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	delta(14)-sterol reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497071.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497134.1
CDS	197..2077
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	XM_006497071.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497071.4

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lbr ( XM_006497070.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497133.1 Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.

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CloneID	OMu10244
Clone ID Related Accession (Same CDS sequence)	XM_006497071.3 , XM_006497071.4 , XM_017313041.1 , NM_133815.2 , XM_006497070.3 , XM_006497070.4
Accession Version	XM_006497070.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	delta(14)-sterol reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497070.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497133.1
CDS	301..2181
Translation	MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY

Target ORF information:

RefSeq Version	XM_006497070.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lamin B receptor (Lbr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497070.4

ORF Insert Sequence:

ATGCCAAGTA GGAAGTTTGT TGAGGGTGAA GTGGTCAGAG GCCGATGGCC TGGGAGCTCC 
CTTTATTATG AAGTAGAGAT TCTGAGCCAC GACAACAAAT CCCAGCTCTA CACTGTAAAA 
TACAAAGATG GCACCGAACT GGAACTGAAG GAGAGTGATA TCAAGCCTTT AAAATCCTTT 
AAGCAAAGAA AAAGTGGCTC GATTTCCAGC TCTCCCTCTC GACGCCGTGG CAGCCGCAGC 
CGCAGCCGCT CAAGATCACG TTCCCGATCC CCGGGCAGAG CACCGAAAGG CTCCAGAAGA 
TCCGTCTCTG CTTCCCATGA GGGTGACGTG AAGGAGAAGA AGGAGAAGGA GATGAGGAGG 
GAAATTCTGC AAGTTAAGCT GACTCCGCTT GTGTTGAAGC CGTTCGGAAA CAGCGTCAGC 
GTGTACAACG GGGAGCCCGA ACACATGGAG AAGAACGCTA CGCCGTATAA AGACAAGCAG 
GAAAGAATCA TTTTGTCAAC AGAAGACAGA TATATAGTTA CACAGTACAG CCTTCGTCCC 
AGGAGAGAAG AGGTCAAAGC CAAAGAAATA GAGTCTGAGG AACAAAACCT TGTCACCAAA 
GGACCCGCAC CTTTGGGAAC CTTTCAAGTG ACCACTCCAC AGAGGAAGGA CTTGGAGTTT 
GGAGGAGTAC CTGGTGCGGT CCTCATCATG CTGGGCCTGC CCGCCTGCGT CCTCTTGCTG 
CTGCTGCAGT GCAGGCAGAA GGACCCGGGG CTGCTCCACT TCCCTCCACC TCTGCCGGCT 
CTCCACGAGC TGTGGGAACC CAGGGTGTGC GGCGTTTACC TCCTCTGGTT TTTCGTTCAA 
GCTCTCTTCC ACCTTCTACC AGTTGGGAAG GTTGCAGAAG GAACACCTCT TGTTGATGGA 
AGAAGACTCC AGTATAGACT GAATGGATTG TATGCCTTCA TTCTGACATC TGCAGCCCTG 
GGAGCAGCTG TCTTCTGGGG TGTTGAGCTG TGCTACCTGT ACACTCACTT CCTGCAGTTG 
GCACTGGCAG CCACCGGGTT CTCCGTGCTC CTGAGTGCTT ACCTCTATGT TCGCTCTCTG 
CGAGCCCCGA GGGAGGAGCT GTCGCCAGCC AGTTCCGGAA ATGCTGTCTA CGACTTCTTC 
ATTGGCCGAG AGTTAAACCC GCGACTTGGT GCTTTCGATC TCAAGTTCTT TTGTGAGTTG 
CGCCCTGGAT TGATTGGATG GGTGGTTATT AACTTAGTGA TGCTTCTGAT GGAAATGAAA 
ATTCAGGAGC GAGCTGCTCC GTCCTTGGCA ATGATCTTGG TTAACAGTTT CCAGCTCTTA 
TATGTGGTGG ACGCCCTCTG GAATGAGGAA GCACTGCTGA CCTCCATGGA CATCATGCAC 
GACGGCTTTG GCTTCATGCT GGCCTTTGGG GATTTAGTGT GGGTTCCATT TACCTACAGC 
CTCCAGGCCT TTTACCTGGT CAGCCATCCC CATGACTTGT CCTGGCCATT GGCTTCTGTC 
ATCATTGCTC TGAAATTGTG TGGATATGTA ATCTTCCGTT GTGCAAACTC TCAGAAAAAT 
GCATTCCGGA AGAATCCCAC TGATCCAAAG CTTGCACATT TGAAGACCAT TCATACTTCC 
ACGGGGAAAA GTCTGCTTGT TTCCGGATGG TGGGGCTTTG TTCGCCATCC CAATTACTTG 
GGTGACCTCA TCATGGCTCT GGCGTGGTCC CTCCCATGTG GTTTCAACCA CCTCCTGCCA 
TACTTCTACA TTATCTACTT CACCGCCTTG CTTATCCATC GAGAGGCCCG GGATGAACAC 
CAGTGCAGGA GGAAGTACGG CCTGGCCTGG GAGAAGTACT GCCAGCGAGT GCCCTACCGC 
ATATTCCCCT ACATTTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accumulation of glycated proteins suggesting premature ageing in lamin B receptor deficient mice.
Biogerontology19(1)95-100(2018 Feb)
Hause F,Schlote D,Simm A,Hoffmann K,Santos AN

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Scientific reports740692(2017 Jan)
Kurogi S,Sekimoto T,Funamoto T,Ota T,Nakamura S,Nagai T,Nakahara M,Yoshinobu K,Araki K,Araki M,Chosa E

Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR).
PloS one12(1)e0169626(2017)
Giannios I,Chatzantonaki E,Georgatos S

Alterations in nuclear structure promote lupus autoimmunity in a mouse model.
Disease models & mechanisms9(8)885-97(2016 08)
Singh N,Johnstone DB,Martin KA,Tempera I,Kaplan MJ,Denny MF

Intrabody-mediated diverting of HP1? to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor.
Experimental cell research338(1)70-81(2015 Oct)
Cardinale A,Filesi I,Singh PB,Biocca S

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Lbr cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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