Coro7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Coro7
Entrez Gene ID	78885
Full Name	coronin 7
Synonyms	0610011B16Rik,AW048373,AW556392
General protein information	Preferred Names coronin 7 Names coronin-7 70 kDa WD repeat tumor rejection antigen homolog crn7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16 A1\|16 2.45 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_030205.4	NP_084481.3	coronin-7

Pathways from BioSystems

Homologies

	CORO7	XP_001097164.2
Mus musculus (house mouse)	Coro7	NP_084481.3
Rattus norvegicus (Norway rat)	Coro7	NP_001178568.1
Danio rerio (zebrafish)	coro7	NP_001025407.1
Caenorhabditis elegans (roundworm)	pod-1	NP_499797.1
Homo sapiens (human)	CORO7	NP_078811.3
Homo sapiens (human)	CORO7-PAM16	NP_001188408.1
Xenopus tropicalis (tropical clawed frog)	coro7	XP_002932508.2
Bos taurus (cattle)	CORO7	NP_001069371.1
Gallus gallus (chicken)	CORO7	NP_001006176.1
Canis lupus familiaris (dog)	CORO7	XP_005621665.1
Drosophila melanogaster (fruit fly)	pod1	NP_727126.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000930	XP_309114.5
Pan troglodytes (chimpanzee)	CORO7	XP_003314984.2

Gene Ontology
Bibliography

Related articles in PubMed

Novel Coronin7 interactions with Cdc42 and N-WASP regulate actin organization and Golgi morphology.
Bhattacharya K, Swaminathan K, Peche VS, Clemen CS, Knyphausen P, Lammers M, Noegel AA, Rastetter RH
Scientific reports625411(2016 05)

Implication of coronin 7 in body weight regulation in humans, mice and flies.
Eriksson A, Williams MJ, Voisin S, Hansson I, Krishnan A, Philippot G, Yamskova O, Herisson FM, Dnyansagar R, Moschonis G, Manios Y, Chrousos GP, Olszewski PK, Frediksson R, Schi?th HB
BMC neuroscience1613(2015 Mar)

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival.
Suo D, Park J, Harrington AW, Zweifel LS, Mihalas S, Deppmann CD
Nature neuroscience17(1)36-45(2014 Jan)

Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.
Watanabe M, Suzuki T, Kim M, Abe Y, Yoshida Y, Sugano S, Yamamoto T
FEBS letters585(1)65-70(2011 Jan)

Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.
Rybakin V, Stumpf M, Schulze A, Majoul IV, Noegel AA, Hasse A
FEBS letters573(1-3)161-7(2004 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

profiling of Coro7 mRNA expression revealed it is highly expressed in appetite and energy balance regulating regions of the brain; food deprivation downregulates hypothalamic Coro7 mRNA; conclude that coronin 7 is involved in the regulation of energy homeostasis and this role stems, to some degree, from the effect on feeding for calories and
Title: Implication of coronin 7 in body weight regulation in humans, mice and flies.

The following Coro7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Coro7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08089	NM_030205.4 Latest version!	Mus musculus coronin 7 (Coro7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$545.30 $779.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Coro7 ( NM_030205.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084481.3 Mus musculus coronin 7 (Coro7), mRNA.

Price & Availability↑

CloneID	OMu08089
Clone ID Related Accession (Same CDS sequence)	NM_030205.4
Accession Version	NM_030205.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2769bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Mus musculus(house mouse)
Product	coronin-7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061006.1. On Jun 10, 2007 this sequence version replaced NM_030205.3. ##Evidence-Data-START## Transcript exon combination :: BC061006.1, AK040408.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGTCGCT TCAAGGTGTC CAAGTTTCGG CATATGGAGG CCCGGCCGTC CCGCCGAGAG 
GCCTGGATCA GTGATATTCG TGCTGTAACC ACCCCCACAT GCGGGAACCA CATCAAATCA 
AGCTGCAGCT TGATCGCTTT CAACTCTGAC CGCCCAGGTG TATTGGGTGT CATATCTCTG 
GAAGGCCATG AGGAAAACAA GAGGCATGTG ACCTACCTTG GCTGTCATTC AGACCTGGTC 
ACTGACCTGG ACTTCTCCCC CTTTGATGAC TTCCTCCTGG CCTCCGGTTC AGCTGACAGG 
ACGATAAAGC TTTGGCGTCT GTCTGGCACT GGAGAAGCGC TTCCCTCTGT GCCTGGAGTG 
GTGCTGGGTC CTGAGGAGCT GCCAGTGGAG GTACTGCAGT TCCACCCCAC TGTAGACGGT 
GTTCTGGTGA GCACAGCTGG CAAGACTGTG AAGGTCTGGG ATGTAGCCAA GCAGCAGCCC 
CTGACAGAGT TGGAGGCCCA CAAGGACCTG GTGCAGAGTG CTGTTTGGAG CCGGGATGGA 
GCCATTGTGG GCACAGCATG TAAGGACAAG CAGCTTCGGA TCTTTGACCC CAGAGCAAGA 
ACCCAGGCTT CTCAGAGCAC ACAGGCCCAT GAGAACAACA GAGACATCCG GTTGGCATGG 
ACAGGCATTC AAGAGCACCT TGTGTCCACT GGATTCAACC AGATGCGTGA GCGAGAAGCG 
AAGCTCTGGG ATACCCGGCT CTTCAGCAGT GCCCTGGCCT CCGTCACCCT GGACACCTCT 
CCTGGGCCTC TGATACCTCT GCTGGATCCA GACTCTGGGC TATTGGTCCT GGCAGGAAAG 
GGTGAGAATC AGCTATACTG TTACGAGGTG ACCCCACAGC AGCCTGCACT GAGCCCAGTG 
ACTCAGTGCA TTCTGGAGAA TGTACTACGA GGAGCAGCCC TTGTTCCCCG GCGAGCACTG 
GCTGTCATGA GTTGCGAGGT GCTCCAAGTC CTGCAGCTGA GTGACACAGC CATCATACCC 
ATCAGCCACC ACGTGCCCCG AAAAGCTGTA GAGTTCCATG AGGACCTGTT TCCAGACACA 
GCCGGTTCTG TGCCTGCTTC TGATGCCCAC ATGTGGTGGG CTGGGGACAA CCAGCAGGTT 
CAGAAGGTCA GCCTCAACCC AGCTCGCCGA CCCCACCCTT GCTTCACGTC CTCCCTGGTG 
CCCACTATGG AACCGGCCCC TGACATGGTC CAGCCTGCAG AGATGCCCAG AGCTGACACA 
GACCTAAGTG AGGGCTTTTC TTCCCCTAGC TCACTGATGT CACCCTCCAC ACCATCCAGT 
CTGGGGCCTT CACTCTCCAG CACGAGCGGC ATTGGTACCA GCCCCAGTCA GAGGTCCCTT 
CAGAGTCTGC TGGGCCCCAG TTCTAAATTT CGCCACACTC AGGGCAGCCT CCTCCACCGC 
GACAGTCACA TCACCAACCT TAAGGGACTC AACCTCACAA CACCTGGTGA GAGTGATGGC 
TTCTGCGCTA ACCGGCTGCG TGTGGCTGTT CCCCTGCTCA GCAGTGGTGG GCAGGTAGCT 
GTGCTTGAGC TGCAGAAGCC AGGCCGCCTG CCTGACACAG CATTGCCTAC ACTTCAGAAT 
GGGACAGCTG TAATGGATCT GGTCTGGGAT CCCTTTGACC CACACCGGCT TGCTGTGGCT 
GGGGAGGATG CCCGGATCCG ACTATGGCGG GTGCCCCCTG GTGGCCTCGA GAATGTTCTC 
ACCACACCTG AGACTGTGCT CACAGGCCAC ACAGAAAAGA TCTACTCTCT GCGCTTCCAC 
CCCCTGGCTG CCGATGTACT GGCTTCCAGT TCCTATGATC TAACCGTTCG CATCTGGGAC 
CTTCAGACTG GAGCTGAGCG GCTGAAACTG CAGGGCCATC AGGACCAGAT TTTTAGCTTG 
GCCTGGAGTC CAGATGGAAA GCAACTGGCC ACCGTATGCA AGGATGGGCA TGTGCGGGTC 
TATGAACCCC GCAGCAGCCC TTTACCCCTA CAGGAAGGCC CAGGACCTGA AGGTGGCCGC 
GGAGCCCGCA TTGTCTGGGT GTGTGATGGT GGTTGCCTGC TGGTTTCTGG CTTTGACAGC 
CGGAGTGAAC GCCAGCTACA GTTGTACATA GCTGACGCCC TGGCACAAGG CCCTTCAGCA 
CTGCTGGGCC TCGATGTAGC TCCCTCGACC CTGCTTCCCA GCTATGACCC TGACACAGGC 
CTGGTGCTTC TCACTGGCAA GGGTGATACC CGTGTGTTCC TGTATGAGGT GCTCCCGGAG 
GCCCCTTTCT TCCTGGAGTG CAACAGCTTC ACATCACCTG ACCCTCACAA GGGTTTTGTC 
CTTCTGCCCA AGACTGAGTG TGACATTCAG GATGTGGAGT TTGCCCGATG CCTGCGGCTG 
CGCCAGACCT CCTTGGAGCC TGTTGCTTTC CGGCTGCCCC GGGTCAGAAA AGAATTCTTC 
CAGGATGATG TGTTCCCGGA CACAGCTGTG ACCTGGGAGC CAGCACTCAG TGCCAAAGCC 
TGGTTTGAGG GTGCTAATGG ACAGCCCCGG CTACTGAGTT TGCAGCCCCC TGGCATGACC 
CCAGTGAGCC AGGCCCCCCG TGAGGTCCCT GCCCGAAGAG CCCCATCTTC AGCACAATAC 
TTGGAAGAGA AGTCTGACCA ACAAAAGAAA GAAGAGCTGC TGAATGCCAT GGTAGCAAAG 
CTGGGGAACC GAGAAGACCC ACTGCCACAG GACTCCTTTG AAGGGGTGGA TGAAGATGAG 
TGGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084481.3
CDS	110..2878
Translation	MSRFKVSKFRHMEARPSRREAWISDIRAVTTPTCGNHIKSSCSLIAFNSDRPGVLGVISLEGHEENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSGTGEALPSVPGVVLGPEELPVEVLQFHPTVDGVLVSTAGKTVKVWDVAKQQPLTELEAHKDLVQSAVWSRDGAIVGTACKDKQLRIFDPRARTQASQSTQAHENNRDIRLAWTGIQEHLVSTGFNQMREREAKLWDTRLFSSALASVTLDTSPGPLIPLLDPDSGLLVLAGKGENQLYCYEVTPQQPALSPVTQCILENVLRGAALVPRRALAVMSCEVLQVLQLSDTAIIPISHHVPRKAVEFHEDLFPDTAGSVPASDAHMWWAGDNQQVQKVSLNPARRPHPCFTSSLVPTMEPAPDMVQPAEMPRADTDLSEGFSSPSSLMSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGSLLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELQKPGRLPDTALPTLQNGTAVMDLVWDPFDPHRLAVAGEDARIRLWRVPPGGLENVLTTPETVLTGHTEKIYSLRFHPLAADVLASSSYDLTVRIWDLQTGAERLKLQGHQDQIFSLAWSPDGKQLATVCKDGHVRVYEPRSSPLPLQEGPGPEGGRGARIVWVCDGGCLLVSGFDSRSERQLQLYIADALAQGPSALLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYEVLPEAPFFLECNSFTSPDPHKGFVLLPKTECDIQDVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWEPALSAKAWFEGANGQPRLLSLQPPGMTPVSQAPREVPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDPLPQDSFEGVDEDEWD

Target ORF information:

RefSeq Version	NM_030205.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus coronin 7 (Coro7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030205.4

ORF Insert Sequence:

ATGAGTCGCT TCAAGGTGTC CAAGTTTCGG CATATGGAGG CCCGGCCGTC CCGCCGAGAG 
GCCTGGATCA GTGATATTCG TGCTGTAACC ACCCCCACAT GCGGGAACCA CATCAAATCA 
AGCTGCAGCT TGATCGCTTT CAACTCTGAC CGCCCAGGTG TATTGGGTGT CATATCTCTG 
GAAGGCCATG AGGAAAACAA GAGGCATGTG ACCTACCTTG GCTGTCATTC AGACCTGGTC 
ACTGACCTGG ACTTCTCCCC CTTTGATGAC TTCCTCCTGG CCTCCGGTTC AGCTGACAGG 
ACGATAAAGC TTTGGCGTCT GTCTGGCACT GGAGAAGCGC TTCCCTCTGT GCCTGGAGTG 
GTGCTGGGTC CTGAGGAGCT GCCAGTGGAG GTACTGCAGT TCCACCCCAC TGTAGACGGT 
GTTCTGGTGA GCACAGCTGG CAAGACTGTG AAGGTCTGGG ATGTAGCCAA GCAGCAGCCC 
CTGACAGAGT TGGAGGCCCA CAAGGACCTG GTGCAGAGTG CTGTTTGGAG CCGGGATGGA 
GCCATTGTGG GCACAGCATG TAAGGACAAG CAGCTTCGGA TCTTTGACCC CAGAGCAAGA 
ACCCAGGCTT CTCAGAGCAC ACAGGCCCAT GAGAACAACA GAGACATCCG GTTGGCATGG 
ACAGGCATTC AAGAGCACCT TGTGTCCACT GGATTCAACC AGATGCGTGA GCGAGAAGCG 
AAGCTCTGGG ATACCCGGCT CTTCAGCAGT GCCCTGGCCT CCGTCACCCT GGACACCTCT 
CCTGGGCCTC TGATACCTCT GCTGGATCCA GACTCTGGGC TATTGGTCCT GGCAGGAAAG 
GGTGAGAATC AGCTATACTG TTACGAGGTG ACCCCACAGC AGCCTGCACT GAGCCCAGTG 
ACTCAGTGCA TTCTGGAGAA TGTACTACGA GGAGCAGCCC TTGTTCCCCG GCGAGCACTG 
GCTGTCATGA GTTGCGAGGT GCTCCAAGTC CTGCAGCTGA GTGACACAGC CATCATACCC 
ATCAGCCACC ACGTGCCCCG AAAAGCTGTA GAGTTCCATG AGGACCTGTT TCCAGACACA 
GCCGGTTCTG TGCCTGCTTC TGATGCCCAC ATGTGGTGGG CTGGGGACAA CCAGCAGGTT 
CAGAAGGTCA GCCTCAACCC AGCTCGCCGA CCCCACCCTT GCTTCACGTC CTCCCTGGTG 
CCCACTATGG AACCGGCCCC TGACATGGTC CAGCCTGCAG AGATGCCCAG AGCTGACACA 
GACCTAAGTG AGGGCTTTTC TTCCCCTAGC TCACTGATGT CACCCTCCAC ACCATCCAGT 
CTGGGGCCTT CACTCTCCAG CACGAGCGGC ATTGGTACCA GCCCCAGTCA GAGGTCCCTT 
CAGAGTCTGC TGGGCCCCAG TTCTAAATTT CGCCACACTC AGGGCAGCCT CCTCCACCGC 
GACAGTCACA TCACCAACCT TAAGGGACTC AACCTCACAA CACCTGGTGA GAGTGATGGC 
TTCTGCGCTA ACCGGCTGCG TGTGGCTGTT CCCCTGCTCA GCAGTGGTGG GCAGGTAGCT 
GTGCTTGAGC TGCAGAAGCC AGGCCGCCTG CCTGACACAG CATTGCCTAC ACTTCAGAAT 
GGGACAGCTG TAATGGATCT GGTCTGGGAT CCCTTTGACC CACACCGGCT TGCTGTGGCT 
GGGGAGGATG CCCGGATCCG ACTATGGCGG GTGCCCCCTG GTGGCCTCGA GAATGTTCTC 
ACCACACCTG AGACTGTGCT CACAGGCCAC ACAGAAAAGA TCTACTCTCT GCGCTTCCAC 
CCCCTGGCTG CCGATGTACT GGCTTCCAGT TCCTATGATC TAACCGTTCG CATCTGGGAC 
CTTCAGACTG GAGCTGAGCG GCTGAAACTG CAGGGCCATC AGGACCAGAT TTTTAGCTTG 
GCCTGGAGTC CAGATGGAAA GCAACTGGCC ACCGTATGCA AGGATGGGCA TGTGCGGGTC 
TATGAACCCC GCAGCAGCCC TTTACCCCTA CAGGAAGGCC CAGGACCTGA AGGTGGCCGC 
GGAGCCCGCA TTGTCTGGGT GTGTGATGGT GGTTGCCTGC TGGTTTCTGG CTTTGACAGC 
CGGAGTGAAC GCCAGCTACA GTTGTACATA GCTGACGCCC TGGCACAAGG CCCTTCAGCA 
CTGCTGGGCC TCGATGTAGC TCCCTCGACC CTGCTTCCCA GCTATGACCC TGACACAGGC 
CTGGTGCTTC TCACTGGCAA GGGTGATACC CGTGTGTTCC TGTATGAGGT GCTCCCGGAG 
GCCCCTTTCT TCCTGGAGTG CAACAGCTTC ACATCACCTG ACCCTCACAA GGGTTTTGTC 
CTTCTGCCCA AGACTGAGTG TGACATTCAG GATGTGGAGT TTGCCCGATG CCTGCGGCTG 
CGCCAGACCT CCTTGGAGCC TGTTGCTTTC CGGCTGCCCC GGGTCAGAAA AGAATTCTTC 
CAGGATGATG TGTTCCCGGA CACAGCTGTG ACCTGGGAGC CAGCACTCAG TGCCAAAGCC 
TGGTTTGAGG GTGCTAATGG ACAGCCCCGG CTACTGAGTT TGCAGCCCCC TGGCATGACC 
CCAGTGAGCC AGGCCCCCCG TGAGGTCCCT GCCCGAAGAG CCCCATCTTC AGCACAATAC 
TTGGAAGAGA AGTCTGACCA ACAAAAGAAA GAAGAGCTGC TGAATGCCAT GGTAGCAAAG 
CTGGGGAACC GAGAAGACCC ACTGCCACAG GACTCCTTTG AAGGGGTGGA TGAAGATGAG 
TGGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel Coronin7 interactions with Cdc42 and N-WASP regulate actin organization and Golgi morphology.
Scientific reports625411(2016 05)
Bhattacharya K,Swaminathan K,Peche VS,Clemen CS,Knyphausen P,Lammers M,Noegel AA,Rastetter RH

Implication of coronin 7 in body weight regulation in humans, mice and flies.
BMC neuroscience1613(2015 Mar)
Eriksson A,Williams MJ,Voisin S,Hansson I,Krishnan A,Philippot G,Yamskova O,Herisson FM,Dnyansagar R,Moschonis G,Manios Y,Chrousos GP,Olszewski PK,Frediksson R,Schi?th HB

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival.
Nature neuroscience17(1)36-45(2014 Jan)
Suo D,Park J,Harrington AW,Zweifel LS,Mihalas S,Deppmann CD

Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.
FEBS letters585(1)65-70(2011 Jan)
Watanabe M,Suzuki T,Kim M,Abe Y,Yoshida Y,Sugano S,Yamamoto T

Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.
FEBS letters573(1-3)161-7(2004 Aug)
Rybakin V,Stumpf M,Schulze A,Majoul IV,Noegel AA,Hasse A