Ddit4 cDNA ORF clone, Mus musculus(house mouse)

RTP801 is a critical factor in the neurodegeneration process of A53T ?-synuclein in a mouse model of Parkinson's disease under chronic restraint stress.
Zhang Z, Chu SF, Wang SS, Jiang YN, Gao Y, Yang PF, Ai QD, Chen NH
British journal of pharmacology(2017 Nov)

Diabetic wild-type mice exhibited functional deficiencies in visual acuity and contrast sensitivity, whereas diabetic REDD1-deficient mice had no visual dysfunction. The results support a role for REDD1 in diabetes-induced retinal neurodegeneration.
Title: Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes.

these data show that REDD1 induction regulates the exercise-mediated change in a distinct set of genes within skeletal muscle.
Title: REDD1 induction regulates the skeletal muscle gene expression signature following acute aerobic exercise.

Findings suggest that REDD1 is a key mediator of cartilage homeostasis through regulation of autophagy and mitochondrial biogenesis and that REDD1 deficiency exacerbates the severity of injury-induced osteoarthritis.
Title: Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.

REDD1 is required for normal insulin-stimulated signaling, and a subtle balance exists between MEK1/2, REDD1, and mTOR
Title: Regulation of skeletal muscle insulin-stimulated signaling through the MEK-REDD1-mTOR axis.

study suggests that VDR regulates Ddit4 expression during epidermal homeostasis and the wound healing process, while elevated Ddit4 represents an early growth-arresting stress response within VDR(-/-) follicles.
Title: DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization.