Xrcc3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Xrcc3
Entrez Gene ID	74335
Full Name	X-ray repair complementing defective repair in Chinese hamster cells 3
General protein information	Preferred Names X-ray repair complementing defective repair in Chinese hamster cells 3 Names DNA repair protein XRCC3 X-ray repair cross-complementing protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 F1
Summary	This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. Allelic variants in the human gene are associated with susceptibility to breast cancer and cutaneous malignant melanoma. [provided by RefSeq, Sep 2015].

mRNA and Protein(s)

mRNA	Protein	Name
XM_030246959.1	XP_030102819.1	DNA repair protein XRCC3 isoform X1
XM_006516300.1	XP_006516363.1	DNA repair protein XRCC3 isoform X2
NM_028875.3	NP_083151.1	DNA repair protein XRCC3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	XRCC3	NP_001071585.1
Danio rerio (zebrafish)	xrcc3	NP_001013559.1
Magnaporthe oryzae (rice blast fungus)	MGG_06985	XP_003709736.1
Arabidopsis thaliana (thale cress)	XRCC3	NP_851202.1
Gallus gallus (chicken)	XRCC3	NP_001006489.1
Schizosaccharomyces pombe (fission yeast)	rhp57	NP_593627.1
Homo sapiens (human)	XRCC3	NP_001093588.1
Pan troglodytes (chimpanzee)	XRCC3	XP_003314577.1
	XRCC3	XP_001083970.1
Canis lupus familiaris (dog)	XRCC3	XP_003435154.1
Neurospora crassa	NCU01771	XP_957194.2
Mus musculus (house mouse)	Xrcc3	NP_083151.1
Rattus norvegicus (Norway rat)	LOC102551085	XP_006240711.1
Drosophila melanogaster (fruit fly)	spn-B	NP_476740.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP013180	XP_003436585.1
Oryza sativa (rice)	Os02g0562100	NP_001047150.1
Xenopus tropicalis (tropical clawed frog)	xrcc3	NP_001016141.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Role of RAD51C and XRCC3 in genetic recombination and DNA repair.
Liu Y, Tarsounas M, O'regan P, West SC
The Journal of biological chemistry282(3)1973-9(2007 Jan)

A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility.
Rafii S, Lindblom A, Reed M, Meuth M, Cox A
Human molecular genetics12(8)915-23(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the RAD51C-XRCC3-associated Holliday junction resolvase complex associates with crossovers and may play an essential role in the resolution of recombination intermediates prior to chromosome segregation
Title: Role of RAD51C and XRCC3 in genetic recombination and DNA repair.

The following Xrcc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Xrcc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06270	NM_028875.3 Latest version!	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu48140	XM_006516300.1 Latest version!	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu06270	XM_030246959.1 Latest version!	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Xrcc3 ( NM_028875.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083151.1 Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), mRNA.

Price & Availability↑

CloneID	OMu06270
Clone ID Related Accession (Same CDS sequence)	XM_030246959.1 , NM_028875.3
Accession Version	NM_028875.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	DNA repair protein XRCC3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC152065.4, BY275474.1, AK014491.1 and BC043073.1. On Sep 19, 2015 this sequence version replaced NM_028875.2. ##Evidence-Data-START## Transcript exon combination :: AK014491.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGCACTGCA TCTGTTCCAG CAGAAGGAGA GCTTCCCTGA GCAGCATCAA 
CGCCTGAGCC TAGGCTGCCC TGTCCTGGAT CAGTTCCTGG GTGGAGGCCT GCCCCTGGAG 
GGCATCACTG GCCTGGCTGG CTGCAGCTCA GCAGGAAAGA CCCAGCTGGC GCTACAGCTC 
TGCCTGGCTG TGCAGTTCCC AAGACAATAT GGAGGCCTAG AGGCCGGGGC TGTCTACATC 
TGCACAGAAG ATGCCTTCCC CAGCAAGCGG CTGTGGCAGC TCATCGCGCA GCAGCGGAGG 
CTGCGGACAG ACGCGCCTGA GGAGCTGATC GAGAAGATCA GGTTCAGCAA CCACATCTTC 
ATTGAACACG CGGCCGACGT GGACACCTTG TTGGAGTGTG TGAGTAAGAA AGTCCCCATC 
CTGCTGTCGA GGGGCATGGC CCGCCTGGTG GTGGTTGACT CCATTGCAGC CCCATTTCGT 
TGTGAGTTCC ACCTTCAGGC CTCAGCCATC AGGGCGAAGC TCCTGCTCTC GCTGGGGGCC 
ACACTGCGAA GACTGAGCAG CACCTTCAGG AGCCCAGTGC TGTGCATCAA CCAGGTGACA 
GACATGGTGG AGGACCAGCA GTCTGTGTCC AGGTCACTAG GGGCTTCAGA AGAGCGCCTC 
TCTCCAGCCC TTGGCATCAC CTGGGCTAAC CAGCTCCTGA TGCGACTGAT GGTTGACCGC 
ACCCATGAGG ACGATGTTAC CACAGGCTTG CCCAGAAGCC CAGTTCGGAC TCTCCGAGTG 
CTCTTCGCCC CCCACCTACC CCTCTCCTCC TGCTGCTACA CAGTCAGTGG GGAAGGCATT 
AGGGGGATGC CAGGAACACA GTCCTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083151.1
CDS	160..1209
Translation	MDLDQLDLNPRITAAVKRGRLKSVKEILCYSGPDLQRLTGLPSHDVQCLLRAASLHLRGSRVLSALHLFQQKESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGCSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIAQQRRLRTDAPEELIEKIRFSNHIFIEHAADVDTLLECVSKKVPILLSRGMARLVVVDSIAAPFRCEFHLQASAIRAKLLLSLGATLRRLSSTFRSPVLCINQVTDMVEDQQSVSRSLGASEERLSPALGITWANQLLMRLMVDRTHEDDVTTGLPRSPVRTLRVLFAPHLPLSSCCYTVSGEGIRGMPGTQSY

Target ORF information:

RefSeq Version	NM_028875.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028875.3

ORF Insert Sequence:

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGCACTGCA TCTGTTCCAG CAGAAGGAGA GCTTCCCTGA GCAGCATCAA 
CGCCTGAGCC TAGGCTGCCC TGTCCTGGAT CAGTTCCTGG GTGGAGGCCT GCCCCTGGAG 
GGCATCACTG GCCTGGCTGG CTGCAGCTCA GCAGGAAAGA CCCAGCTGGC GCTACAGCTC 
TGCCTGGCTG TGCAGTTCCC AAGACAATAT GGAGGCCTAG AGGCCGGGGC TGTCTACATC 
TGCACAGAAG ATGCCTTCCC CAGCAAGCGG CTGTGGCAGC TCATCGCGCA GCAGCGGAGG 
CTGCGGACAG ACGCGCCTGA GGAGCTGATC GAGAAGATCA GGTTCAGCAA CCACATCTTC 
ATTGAACACG CGGCCGACGT GGACACCTTG TTGGAGTGTG TGAGTAAGAA AGTCCCCATC 
CTGCTGTCGA GGGGCATGGC CCGCCTGGTG GTGGTTGACT CCATTGCAGC CCCATTTCGT 
TGTGAGTTCC ACCTTCAGGC CTCAGCCATC AGGGCGAAGC TCCTGCTCTC GCTGGGGGCC 
ACACTGCGAA GACTGAGCAG CACCTTCAGG AGCCCAGTGC TGTGCATCAA CCAGGTGACA 
GACATGGTGG AGGACCAGCA GTCTGTGTCC AGGTCACTAG GGGCTTCAGA AGAGCGCCTC 
TCTCCAGCCC TTGGCATCAC CTGGGCTAAC CAGCTCCTGA TGCGACTGAT GGTTGACCGC 
ACCCATGAGG ACGATGTTAC CACAGGCTTG CCCAGAAGCC CAGTTCGGAC TCTCCGAGTG 
CTCTTCGCCC CCCACCTACC CCTCTCCTCC TGCTGCTACA CAGTCAGTGG GGAAGGCATT 
AGGGGGATGC CAGGAACACA GTCCTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Xrcc3 ( XM_006516300.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006516363.1 Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu48140
Clone ID Related Accession (Same CDS sequence)	XM_006516300.1
Accession Version	XM_006516300.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	DNA repair protein XRCC3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGGGGCTGT CTACATCTGC ACAGAAGATG CCTTCCCCAG CAAGCGGCTG 
TGGCAGCTCA TCGCGCAGCA GCGGAGGCTG CGGACAGACG CGCCTGAGGA GCTGATCGAG 
AAGATCAGGT TCAGCAACCA CATCTTCATT GAACACGCGG CCGACGTGGA CACCTTGTTG 
GAGTGTGTGA GTAAGAAAGT CCCCATCCTG CTGTCGAGGG GCATGGCCCG CCTGGTGGTG 
GTTGACTCCA TTGCAGCCCC ATTTCGTTGT GAGTTCCACC TTCAGGCCTC AGCCATCAGG 
GCGAAGCTCC TGCTCTCGCT GGGGGCCACA CTGCGAAGAC TGAGCAGCAC CTTCAGGAGC 
CCAGTGCTGT GCATCAACCA GGTGACAGAC ATGGTGGAGG ACCAGCAGTC TGTGTCCAGG 
TCACTAGGGG CTTCAGAAGA GCGCCTCTCT CCAGCCCTTG GCATCACCTG GGCTAACCAG 
CTCCTGATGC GACTGATGGT TGACCGCACC CATGAGGACG ATGTTACCAC AGGCTTGCCC 
AGAAGCCCAG TTCGGACTCT CCGAGTGCTC TTCGCCCCCC ACCTACCCCT CTCCTCCTGC 
TGCTACACAG TCAGTGGGGA AGGCATTAGG GGGATGCCAG GAACACAGTC CTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006516363.1
CDS	334..1170
Translation	MDLDQLDLNPRITAAVKRGRLKSVKEILCYSGPDLQRLTGLPSHDVQCLLRAASLHLRGSRVLSGAVYICTEDAFPSKRLWQLIAQQRRLRTDAPEELIEKIRFSNHIFIEHAADVDTLLECVSKKVPILLSRGMARLVVVDSIAAPFRCEFHLQASAIRAKLLLSLGATLRRLSSTFRSPVLCINQVTDMVEDQQSVSRSLGASEERLSPALGITWANQLLMRLMVDRTHEDDVTTGLPRSPVRTLRVLFAPHLPLSSCCYTVSGEGIRGMPGTQSY

Target ORF information:

RefSeq Version	XM_006516300.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516300.1

ORF Insert Sequence:

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGGGGCTGT CTACATCTGC ACAGAAGATG CCTTCCCCAG CAAGCGGCTG 
TGGCAGCTCA TCGCGCAGCA GCGGAGGCTG CGGACAGACG CGCCTGAGGA GCTGATCGAG 
AAGATCAGGT TCAGCAACCA CATCTTCATT GAACACGCGG CCGACGTGGA CACCTTGTTG 
GAGTGTGTGA GTAAGAAAGT CCCCATCCTG CTGTCGAGGG GCATGGCCCG CCTGGTGGTG 
GTTGACTCCA TTGCAGCCCC ATTTCGTTGT GAGTTCCACC TTCAGGCCTC AGCCATCAGG 
GCGAAGCTCC TGCTCTCGCT GGGGGCCACA CTGCGAAGAC TGAGCAGCAC CTTCAGGAGC 
CCAGTGCTGT GCATCAACCA GGTGACAGAC ATGGTGGAGG ACCAGCAGTC TGTGTCCAGG 
TCACTAGGGG CTTCAGAAGA GCGCCTCTCT CCAGCCCTTG GCATCACCTG GGCTAACCAG 
CTCCTGATGC GACTGATGGT TGACCGCACC CATGAGGACG ATGTTACCAC AGGCTTGCCC 
AGAAGCCCAG TTCGGACTCT CCGAGTGCTC TTCGCCCCCC ACCTACCCCT CTCCTCCTGC 
TGCTACACAG TCAGTGGGGA AGGCATTAGG GGGATGCCAG GAACACAGTC CTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Xrcc3 ( XM_030246959.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102819.1 Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu06270
Clone ID Related Accession (Same CDS sequence)	XM_030246959.1 , NM_028875.3
Accession Version	XM_030246959.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	DNA repair protein XRCC3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGCACTGCA TCTGTTCCAG CAGAAGGAGA GCTTCCCTGA GCAGCATCAA 
CGCCTGAGCC TAGGCTGCCC TGTCCTGGAT CAGTTCCTGG GTGGAGGCCT GCCCCTGGAG 
GGCATCACTG GCCTGGCTGG CTGCAGCTCA GCAGGAAAGA CCCAGCTGGC GCTACAGCTC 
TGCCTGGCTG TGCAGTTCCC AAGACAATAT GGAGGCCTAG AGGCCGGGGC TGTCTACATC 
TGCACAGAAG ATGCCTTCCC CAGCAAGCGG CTGTGGCAGC TCATCGCGCA GCAGCGGAGG 
CTGCGGACAG ACGCGCCTGA GGAGCTGATC GAGAAGATCA GGTTCAGCAA CCACATCTTC 
ATTGAACACG CGGCCGACGT GGACACCTTG TTGGAGTGTG TGAGTAAGAA AGTCCCCATC 
CTGCTGTCGA GGGGCATGGC CCGCCTGGTG GTGGTTGACT CCATTGCAGC CCCATTTCGT 
TGTGAGTTCC ACCTTCAGGC CTCAGCCATC AGGGCGAAGC TCCTGCTCTC GCTGGGGGCC 
ACACTGCGAA GACTGAGCAG CACCTTCAGG AGCCCAGTGC TGTGCATCAA CCAGGTGACA 
GACATGGTGG AGGACCAGCA GTCTGTGTCC AGGTCACTAG GGGCTTCAGA AGAGCGCCTC 
TCTCCAGCCC TTGGCATCAC CTGGGCTAAC CAGCTCCTGA TGCGACTGAT GGTTGACCGC 
ACCCATGAGG ACGATGTTAC CACAGGCTTG CCCAGAAGCC CAGTTCGGAC TCTCCGAGTG 
CTCTTCGCCC CCCACCTACC CCTCTCCTCC TGCTGCTACA CAGTCAGTGG GGAAGGCATT 
AGGGGGATGC CAGGAACACA GTCCTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102819.1
CDS	860..1909
Translation	MDLDQLDLNPRITAAVKRGRLKSVKEILCYSGPDLQRLTGLPSHDVQCLLRAASLHLRGSRVLSALHLFQQKESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGCSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIAQQRRLRTDAPEELIEKIRFSNHIFIEHAADVDTLLECVSKKVPILLSRGMARLVVVDSIAAPFRCEFHLQASAIRAKLLLSLGATLRRLSSTFRSPVLCINQVTDMVEDQQSVSRSLGASEERLSPALGITWANQLLMRLMVDRTHEDDVTTGLPRSPVRTLRVLFAPHLPLSSCCYTVSGEGIRGMPGTQSY

Target ORF information:

RefSeq Version	XM_030246959.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246959.1

ORF Insert Sequence:

ATGGACTTGG ATCAGCTGGA CCTAAACCCC CGAATTACTG CTGCGGTTAA GAGGGGCAGA 
CTGAAGTCAG TGAAGGAGAT TCTGTGCTAC TCCGGACCAG ACTTGCAGCG GCTCACCGGC 
CTGCCCAGCC ACGATGTGCA GTGCCTGCTG AGAGCTGCCT CTCTACACCT TCGGGGAAGC 
CGCGTCCTCT CAGCACTGCA TCTGTTCCAG CAGAAGGAGA GCTTCCCTGA GCAGCATCAA 
CGCCTGAGCC TAGGCTGCCC TGTCCTGGAT CAGTTCCTGG GTGGAGGCCT GCCCCTGGAG 
GGCATCACTG GCCTGGCTGG CTGCAGCTCA GCAGGAAAGA CCCAGCTGGC GCTACAGCTC 
TGCCTGGCTG TGCAGTTCCC AAGACAATAT GGAGGCCTAG AGGCCGGGGC TGTCTACATC 
TGCACAGAAG ATGCCTTCCC CAGCAAGCGG CTGTGGCAGC TCATCGCGCA GCAGCGGAGG 
CTGCGGACAG ACGCGCCTGA GGAGCTGATC GAGAAGATCA GGTTCAGCAA CCACATCTTC 
ATTGAACACG CGGCCGACGT GGACACCTTG TTGGAGTGTG TGAGTAAGAA AGTCCCCATC 
CTGCTGTCGA GGGGCATGGC CCGCCTGGTG GTGGTTGACT CCATTGCAGC CCCATTTCGT 
TGTGAGTTCC ACCTTCAGGC CTCAGCCATC AGGGCGAAGC TCCTGCTCTC GCTGGGGGCC 
ACACTGCGAA GACTGAGCAG CACCTTCAGG AGCCCAGTGC TGTGCATCAA CCAGGTGACA 
GACATGGTGG AGGACCAGCA GTCTGTGTCC AGGTCACTAG GGGCTTCAGA AGAGCGCCTC 
TCTCCAGCCC TTGGCATCAC CTGGGCTAAC CAGCTCCTGA TGCGACTGAT GGTTGACCGC 
ACCCATGAGG ACGATGTTAC CACAGGCTTG CCCAGAAGCC CAGTTCGGAC TCTCCGAGTG 
CTCTTCGCCC CCCACCTACC CCTCTCCTCC TGCTGCTACA CAGTCAGTGG GGAAGGCATT 
AGGGGGATGC CAGGAACACA GTCCTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
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Xrcc3 cDNA ORF clone, Mus musculus(house mouse)

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