Ripk4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ripk4
Entrez Gene ID	72388
Full Name	receptor-interacting serine-threonine kinase 4
Synonyms	2310069J12Rik,AI552420,ANKK2,Ankrd3,DIk,PKK,RIP4
General protein information	Preferred Names receptor-interacting serine-threonine kinase 4 Names receptor-interacting serine/threonine-protein kinase 4 PKC-associated protein kinase PKC-regulated protein kinase ankyrin repeat domain 3 ankyrin repeat domain-containing protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 C4

mRNA and Protein(s)

mRNA	Protein	Name
NM_023663.6	NP_076152.2	receptor-interacting serine/threonine-protein kinase 4
XM_011246154.2	XP_011244456.1	receptor-interacting serine/threonine-protein kinase 4 isoform X1
NM_023663.7	NP_076152.2	receptor-interacting serine/threonine-protein kinase 4

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RIPK4	XP_005639054.1
Rattus norvegicus (Norway rat)	Ripk4	NP_001100573.1
Danio rerio (zebrafish)	ripk4	NP_998243.1
	RIPK4	XP_001107026.1
Bos taurus (cattle)	RIPK4	NP_001093797.1
Mus musculus (house mouse)	Ripk4	NP_076152.2
Xenopus tropicalis (tropical clawed frog)	ripk4	XP_002941332.1
Gallus gallus (chicken)	RIPK4	XP_416738.3
Homo sapiens (human)	RIPK4	NP_065690.2
Pan troglodytes (chimpanzee)	RIPK4	XP_001134659.1

Gene Ontology
Bibliography

Related articles in PubMed

Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation.
Urwyler-R?sselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W
The Journal of investigative dermatology(2018 Jan)

PKK Deletion in Basal Keratinocytes Promotes Tumorigenesis After Chemical Carcinogenesis.
Chen L, Hayden MS, Gilmore ES, Alexander-Savino C, Oleksyn D, Gillespie K, Zhao J, Poligone B
Carcinogenesis(2017 Nov)

Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
Lee P, Jiang S, Li Y, Yue J, Gou X, Chen SY, Zhao Y, Schober M, Tan M, Wu X
The EMBO journal36(13)1963-1980(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This approach identified a key signaling event, phosphorylation of a desmosome component, PKP1 (plakophilin-1) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal differentiation.
Title: Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.

these results reveal a critical role of PKK in the maintenance of recirculating mature B cells as well as the development of B1 cells in mice
Title: A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells.

RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation
Title: RIP4 regulates epidermal differentiation and cutaneous inflammation.

NF-kappaB activity and keratinocyte differentiation are regulated by the RIP4 protein, which has roles in cutaneous wound repair
Title: Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair.

PKK is not required for the production of B cells in the bone marrow or for the development and maintenance of all mature B lymphocyte populations.
Title: Protein kinase C-associated kinase is not required for the development of peripheral B lymphocyte populations.

The following Ripk4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ripk4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05348	NM_023663.7 Latest version!	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$461.30 $659.00
OMu70903	XM_011246154.2 Latest version!	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OMu05348	NM_023663.6	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$461.30 $659.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ripk4 ( NM_023663.6 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_076152.2 Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.

Price & Availability↑

CloneID	OMu05348
Clone ID Related Accession (Same CDS sequence)	NM_023663.6 , NM_023663.7
Accession Version	NM_023663.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2361bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Mus musculus(house mouse)
Product	receptor-interacting serine/threonine-protein kinase 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC121560.17. On Oct 19, 2007 this sequence version replaced NM_023663.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF302127.3, AK145203.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGGCG AGGGCCGGGG CCGGTGGGCT CTGGGGCTGC TGCGCACCTT CGACGCCGGC 
GAATTCGCAG GCTGGGAGAA GGTGGGCTCG GGCGGCTTCG GGCAGGTGTA CAAGGTGCGC 
CATGTGCACT GGAAGACGTG GCTCGCGATC AAGTGCTCGC CCAGTCTGCA CGTCGACGAC 
AGGGAACGAA TGGAGCTCCT GGAGGAAGCT AAGAAGATGG AGATGGCCAA GTTCCGATAC 
ATTCTACCTG TGTACGGCAT ATGCCAGGAA CCTGTCGGCT TGGTCATGGA GTACATGGAG 
ACAGGCTCCC TGGAGAAGCT GCTGGCCTCA GAGCCATTGC CTTGGGACCT GCGCTTTCGC 
ATCGTGCACG AGACAGCCGT GGGCATGAAC TTCCTGCATT GCATGTCTCC GCCACTGCTG 
CACCTAGACC TGAAGCCAGC GAACATCCTG CTGGATGCCC ACTACCATGT CAAGATTTCT 
GACTTTGGGC TGGCCAAGTG CAATGGCATG TCCCACTCTC ATGACCTCAG CATGGATGGC 
CTGTTTGGTA CAATCGCTTA CCTCCCTCCA GAGCGAATTC GTGAGAAGAG CCGCTTGTTT 
GACACCAAAC ATGATGTATA CAGCTTCGCC ATTGTGATCT GGGGTGTGCT TACACAGAAG 
AAGCCATTTG CAGATGAAAA GAACATCCTA CACATCATGA TGAAAGTGGT AAAGGGCCAC 
CGCCCAGAGC TGCCACCCAT CTGCAGACCC CGGCCGCGTG CCTGTGCCAG CCTGATAGGG 
CTCATGCAAC GGTGCTGGCA TGCAGACCCA CAGGTGCGGC CCACCTTCCA AGAAATTACC 
TCTGAAACAG AAGACCTTTG TGAGAAGCCT GATGAGGAGG TGAAAGACCT GGCTCATGAG 
CCAGGCGAGA AAAGCTCTCT AGAGTCCAAG AGTGAGGCCA GGCCCGAGTC CTCACGCCTC 
AAGCGCGCCT CTGCTCCCCC CTTCGATAAC GACTGCAGTC TCTCCGAGTT GCTGTCACAG 
TTGGACTCTG GGATCTCCCA GACTCTTGAA GGCCCCGAAG AGCTCAGCCG AAGTTCCTCT 
GAATGCAAGC TCCCATCGTC CAGCAGTGGC AAGAGGCTCT CGGGGGTGTC CTCAGTGGAC 
TCAGCCTTTT CCTCCAGAGG ATCGCTGTCA CTGTCTTTTG AGCGGGAAGC TTCAACAGGC 
GACCTGGGCC CCACAGACAT CCAGAAGAAG AAGCTAGTGG ATGCCATCAT ATCAGGGGAC 
ACCAGCAGGC TGATGAAGAT CCTACAGCCC CAAGATGTGG ACTTGGTTCT AGACAGCAGT 
GCCAGCCTGC TGCACCTGGC TGTGGAGGCC GGACAGGAGG AGTGTGTCAA GTGGCTGCTG 
CTTAACAATG CCAACCCCAA CCTGACCAAC AGGAAGGGCT CTACACCACT GCATATGGCT 
GTGGAGCGGA AGGGACGTGG AATTGTGGAG CTACTGCTAG CCCGGAAGAC CAGTGTCAAT 
GCCAAGGATG AAGACCAGTG GACTGCCCTG CACTTTGCAG CCCAGAATGG GGATGAGGCC 
AGCACAAGGC TGCTGCTAGA GAAGAATGCT TCTGTCAATG AGGTGGACTT TGAGGGCCGA 
ACACCCATGC ATGTAGCCTG CCAGCATGGA CAGGAGAACA TTGTGCGCAC CCTGCTCCGC 
CGTGGTGTGG ATGTGGGCCT GCAGGGAAAG GATGCCTGGT TGCCTCTGCA CTATGCTGCC 
TGGCAGGGCC ACCTTCCCAT TGTTAAGCTG CTAGCCAAGC AGCCTGGGGT GAGTGTGAAT 
GCCCAGACAC TAGACGGGAG GACACCCCTG CACCTGGCTG CTCAGAGGGG GCATTACCGT 
GTGGCTCGCA TTCTCATTGA CCTGTGCTCT GATGTTAACA TCTGCAGCCT ACAGGCACAG 
ACACCTCTGC ATGTTGCTGC AGAGACTGGA CACACTAGTA CTGCCAGGCT ACTCTTGCAT 
CGTGGTGCTG GCAAGGAGGC TTTGACCTCA GAGGGCTATA CTGCCTTGCA CCTGGCAGCC 
CAGAATGGAC ACCTGGCTAC TGTCAAGCTG CTCATAGAGG AGAAGGCTGA TGTGATGGCT 
CGGGGTCCCC TGAATCAGAC AGCACTGCAC CTGGCTGCTG CCCGTGGACA CTCAGAGGTG 
GTAGAAGAGC TGGTCAGTGC TGACCTCATT GACCTGTCTG ATGAGCAGGG CCTCAGCGCA 
CTGCACCTGG CTGCTCAGGG CAGGCATTCA CAGACTGTGG AGACACTGCT CAAACATGGA 
GCACACATCA ACTTGCAGAG TCTCAAGTTC CAAGGAGGCC AGAGCTCTGC TGCCACGTTG 
CTCCGACGCA GCAAGACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076152.2
CDS	47..2407
Translation	MEGEGRGRWALGLLRTFDAGEFAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEKPDEEVKDLAHEPGEKSSLESKSEARPESSRLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIISGDTSRLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAAQNGHLATVKLLIEEKADVMARGPLNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVETLLKHGAHINLQSLKFQGGQSSAATLLRRSKT

Target ORF information:

RefSeq Version	NM_023663.6
Organism	Mus musculus(house mouse)
Definition	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023663.6

ORF Insert Sequence:

ATGGAGGGCG AGGGCCGGGG CCGGTGGGCT CTGGGGCTGC TGCGCACCTT CGACGCCGGC 
GAATTCGCAG GCTGGGAGAA GGTGGGCTCG GGCGGCTTCG GGCAGGTGTA CAAGGTGCGC 
CATGTGCACT GGAAGACGTG GCTCGCGATC AAGTGCTCGC CCAGTCTGCA CGTCGACGAC 
AGGGAACGAA TGGAGCTCCT GGAGGAAGCT AAGAAGATGG AGATGGCCAA GTTCCGATAC 
ATTCTACCTG TGTACGGCAT ATGCCAGGAA CCTGTCGGCT TGGTCATGGA GTACATGGAG 
ACAGGCTCCC TGGAGAAGCT GCTGGCCTCA GAGCCATTGC CTTGGGACCT GCGCTTTCGC 
ATCGTGCACG AGACAGCCGT GGGCATGAAC TTCCTGCATT GCATGTCTCC GCCACTGCTG 
CACCTAGACC TGAAGCCAGC GAACATCCTG CTGGATGCCC ACTACCATGT CAAGATTTCT 
GACTTTGGGC TGGCCAAGTG CAATGGCATG TCCCACTCTC ATGACCTCAG CATGGATGGC 
CTGTTTGGTA CAATCGCTTA CCTCCCTCCA GAGCGAATTC GTGAGAAGAG CCGCTTGTTT 
GACACCAAAC ATGATGTATA CAGCTTCGCC ATTGTGATCT GGGGTGTGCT TACACAGAAG 
AAGCCATTTG CAGATGAAAA GAACATCCTA CACATCATGA TGAAAGTGGT AAAGGGCCAC 
CGCCCAGAGC TGCCACCCAT CTGCAGACCC CGGCCGCGTG CCTGTGCCAG CCTGATAGGG 
CTCATGCAAC GGTGCTGGCA TGCAGACCCA CAGGTGCGGC CCACCTTCCA AGAAATTACC 
TCTGAAACAG AAGACCTTTG TGAGAAGCCT GATGAGGAGG TGAAAGACCT GGCTCATGAG 
CCAGGCGAGA AAAGCTCTCT AGAGTCCAAG AGTGAGGCCA GGCCCGAGTC CTCACGCCTC 
AAGCGCGCCT CTGCTCCCCC CTTCGATAAC GACTGCAGTC TCTCCGAGTT GCTGTCACAG 
TTGGACTCTG GGATCTCCCA GACTCTTGAA GGCCCCGAAG AGCTCAGCCG AAGTTCCTCT 
GAATGCAAGC TCCCATCGTC CAGCAGTGGC AAGAGGCTCT CGGGGGTGTC CTCAGTGGAC 
TCAGCCTTTT CCTCCAGAGG ATCGCTGTCA CTGTCTTTTG AGCGGGAAGC TTCAACAGGC 
GACCTGGGCC CCACAGACAT CCAGAAGAAG AAGCTAGTGG ATGCCATCAT ATCAGGGGAC 
ACCAGCAGGC TGATGAAGAT CCTACAGCCC CAAGATGTGG ACTTGGTTCT AGACAGCAGT 
GCCAGCCTGC TGCACCTGGC TGTGGAGGCC GGACAGGAGG AGTGTGTCAA GTGGCTGCTG 
CTTAACAATG CCAACCCCAA CCTGACCAAC AGGAAGGGCT CTACACCACT GCATATGGCT 
GTGGAGCGGA AGGGACGTGG AATTGTGGAG CTACTGCTAG CCCGGAAGAC CAGTGTCAAT 
GCCAAGGATG AAGACCAGTG GACTGCCCTG CACTTTGCAG CCCAGAATGG GGATGAGGCC 
AGCACAAGGC TGCTGCTAGA GAAGAATGCT TCTGTCAATG AGGTGGACTT TGAGGGCCGA 
ACACCCATGC ATGTAGCCTG CCAGCATGGA CAGGAGAACA TTGTGCGCAC CCTGCTCCGC 
CGTGGTGTGG ATGTGGGCCT GCAGGGAAAG GATGCCTGGT TGCCTCTGCA CTATGCTGCC 
TGGCAGGGCC ACCTTCCCAT TGTTAAGCTG CTAGCCAAGC AGCCTGGGGT GAGTGTGAAT 
GCCCAGACAC TAGACGGGAG GACACCCCTG CACCTGGCTG CTCAGAGGGG GCATTACCGT 
GTGGCTCGCA TTCTCATTGA CCTGTGCTCT GATGTTAACA TCTGCAGCCT ACAGGCACAG 
ACACCTCTGC ATGTTGCTGC AGAGACTGGA CACACTAGTA CTGCCAGGCT ACTCTTGCAT 
CGTGGTGCTG GCAAGGAGGC TTTGACCTCA GAGGGCTATA CTGCCTTGCA CCTGGCAGCC 
CAGAATGGAC ACCTGGCTAC TGTCAAGCTG CTCATAGAGG AGAAGGCTGA TGTGATGGCT 
CGGGGTCCCC TGAATCAGAC AGCACTGCAC CTGGCTGCTG CCCGTGGACA CTCAGAGGTG 
GTAGAAGAGC TGGTCAGTGC TGACCTCATT GACCTGTCTG ATGAGCAGGG CCTCAGCGCA 
CTGCACCTGG CTGCTCAGGG CAGGCATTCA CAGACTGTGG AGACACTGCT CAAACATGGA 
GCACACATCA ACTTGCAGAG TCTCAAGTTC CAAGGAGGCC AGAGCTCTGC TGCCACGTTG 
CTCCGACGCA GCAAGACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ripk4 ( NM_023663.7 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_076152.2 Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.

Price & Availability↑

CloneID	OMu05348
Clone ID Related Accession (Same CDS sequence)	NM_023663.6 , NM_023663.7
Accession Version	NM_023663.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2361bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Mus musculus(house mouse)
Product	receptor-interacting serine/threonine-protein kinase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121560.17. On Apr 20, 2018 this sequence version replaced NM_023663.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057871.1, AF302127.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGGCG AGGGCCGGGG CCGGTGGGCT CTGGGGCTGC TGCGCACCTT CGACGCCGGC 
GAATTCGCAG GCTGGGAGAA GGTGGGCTCG GGCGGCTTCG GGCAGGTGTA CAAGGTGCGC 
CATGTGCACT GGAAGACGTG GCTCGCGATC AAGTGCTCGC CCAGTCTGCA CGTCGACGAC 
AGGGAACGAA TGGAGCTCCT GGAGGAAGCT AAGAAGATGG AGATGGCCAA GTTCCGATAC 
ATTCTACCTG TGTACGGCAT ATGCCAGGAA CCTGTCGGCT TGGTCATGGA GTACATGGAG 
ACAGGCTCCC TGGAGAAGCT GCTGGCCTCA GAGCCATTGC CTTGGGACCT GCGCTTTCGC 
ATCGTGCACG AGACAGCCGT GGGCATGAAC TTCCTGCATT GCATGTCTCC GCCACTGCTG 
CACCTAGACC TGAAGCCAGC GAACATCCTG CTGGATGCCC ACTACCATGT CAAGATTTCT 
GACTTTGGGC TGGCCAAGTG CAATGGCATG TCCCACTCTC ATGACCTCAG CATGGATGGC 
CTGTTTGGTA CAATCGCTTA CCTCCCTCCA GAGCGAATTC GTGAGAAGAG CCGCTTGTTT 
GACACCAAAC ATGATGTATA CAGCTTCGCC ATTGTGATCT GGGGTGTGCT TACACAGAAG 
AAGCCATTTG CAGATGAAAA GAACATCCTA CACATCATGA TGAAAGTGGT AAAGGGCCAC 
CGCCCAGAGC TGCCACCCAT CTGCAGACCC CGGCCGCGTG CCTGTGCCAG CCTGATAGGG 
CTCATGCAAC GGTGCTGGCA TGCAGACCCA CAGGTGCGGC CCACCTTCCA AGAAATTACC 
TCTGAAACAG AAGACCTTTG TGAGAAGCCT GATGAGGAGG TGAAAGACCT GGCTCATGAG 
CCAGGCGAGA AAAGCTCTCT AGAGTCCAAG AGTGAGGCCA GGCCCGAGTC CTCACGCCTC 
AAGCGCGCCT CTGCTCCCCC CTTCGATAAC GACTGCAGTC TCTCCGAGTT GCTGTCACAG 
TTGGACTCTG GGATCTCCCA GACTCTTGAA GGCCCCGAAG AGCTCAGCCG AAGTTCCTCT 
GAATGCAAGC TCCCATCGTC CAGCAGTGGC AAGAGGCTCT CGGGGGTGTC CTCAGTGGAC 
TCAGCCTTTT CCTCCAGAGG ATCGCTGTCA CTGTCTTTTG AGCGGGAAGC TTCAACAGGC 
GACCTGGGCC CCACAGACAT CCAGAAGAAG AAGCTAGTGG ATGCCATCAT ATCAGGGGAC 
ACCAGCAGGC TGATGAAGAT CCTACAGCCC CAAGATGTGG ACTTGGTTCT AGACAGCAGT 
GCCAGCCTGC TGCACCTGGC TGTGGAGGCC GGACAGGAGG AGTGTGTCAA GTGGCTGCTG 
CTTAACAATG CCAACCCCAA CCTGACCAAC AGGAAGGGCT CTACACCACT GCATATGGCT 
GTGGAGCGGA AGGGACGTGG AATTGTGGAG CTACTGCTAG CCCGGAAGAC CAGTGTCAAT 
GCCAAGGATG AAGACCAGTG GACTGCCCTG CACTTTGCAG CCCAGAATGG GGATGAGGCC 
AGCACAAGGC TGCTGCTAGA GAAGAATGCT TCTGTCAATG AGGTGGACTT TGAGGGCCGA 
ACACCCATGC ATGTAGCCTG CCAGCATGGA CAGGAGAACA TTGTGCGCAC CCTGCTCCGC 
CGTGGTGTGG ATGTGGGCCT GCAGGGAAAG GATGCCTGGT TGCCTCTGCA CTATGCTGCC 
TGGCAGGGCC ACCTTCCCAT TGTTAAGCTG CTAGCCAAGC AGCCTGGGGT GAGTGTGAAT 
GCCCAGACAC TAGACGGGAG GACACCCCTG CACCTGGCTG CTCAGAGGGG GCATTACCGT 
GTGGCTCGCA TTCTCATTGA CCTGTGCTCT GATGTTAACA TCTGCAGCCT ACAGGCACAG 
ACACCTCTGC ATGTTGCTGC AGAGACTGGA CACACTAGTA CTGCCAGGCT ACTCTTGCAT 
CGTGGTGCTG GCAAGGAGGC TTTGACCTCA GAGGGCTATA CTGCCTTGCA CCTGGCAGCC 
CAGAATGGAC ACCTGGCTAC TGTCAAGCTG CTCATAGAGG AGAAGGCTGA TGTGATGGCT 
CGGGGTCCCC TGAATCAGAC AGCACTGCAC CTGGCTGCTG CCCGTGGACA CTCAGAGGTG 
GTAGAAGAGC TGGTCAGTGC TGACCTCATT GACCTGTCTG ATGAGCAGGG CCTCAGCGCA 
CTGCACCTGG CTGCTCAGGG CAGGCATTCA CAGACTGTGG AGACACTGCT CAAACATGGA 
GCACACATCA ACTTGCAGAG TCTCAAGTTC CAAGGAGGCC AGAGCTCTGC TGCCACGTTG 
CTCCGACGCA GCAAGACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076152.2
CDS	71..2431
Translation	MEGEGRGRWALGLLRTFDAGEFAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEKPDEEVKDLAHEPGEKSSLESKSEARPESSRLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIISGDTSRLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAAQNGHLATVKLLIEEKADVMARGPLNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVETLLKHGAHINLQSLKFQGGQSSAATLLRRSKT

Target ORF information:

RefSeq Version	NM_023663.7
Organism	Mus musculus(house mouse)
Definition	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023663.7

ORF Insert Sequence:

ATGGAGGGCG AGGGCCGGGG CCGGTGGGCT CTGGGGCTGC TGCGCACCTT CGACGCCGGC 
GAATTCGCAG GCTGGGAGAA GGTGGGCTCG GGCGGCTTCG GGCAGGTGTA CAAGGTGCGC 
CATGTGCACT GGAAGACGTG GCTCGCGATC AAGTGCTCGC CCAGTCTGCA CGTCGACGAC 
AGGGAACGAA TGGAGCTCCT GGAGGAAGCT AAGAAGATGG AGATGGCCAA GTTCCGATAC 
ATTCTACCTG TGTACGGCAT ATGCCAGGAA CCTGTCGGCT TGGTCATGGA GTACATGGAG 
ACAGGCTCCC TGGAGAAGCT GCTGGCCTCA GAGCCATTGC CTTGGGACCT GCGCTTTCGC 
ATCGTGCACG AGACAGCCGT GGGCATGAAC TTCCTGCATT GCATGTCTCC GCCACTGCTG 
CACCTAGACC TGAAGCCAGC GAACATCCTG CTGGATGCCC ACTACCATGT CAAGATTTCT 
GACTTTGGGC TGGCCAAGTG CAATGGCATG TCCCACTCTC ATGACCTCAG CATGGATGGC 
CTGTTTGGTA CAATCGCTTA CCTCCCTCCA GAGCGAATTC GTGAGAAGAG CCGCTTGTTT 
GACACCAAAC ATGATGTATA CAGCTTCGCC ATTGTGATCT GGGGTGTGCT TACACAGAAG 
AAGCCATTTG CAGATGAAAA GAACATCCTA CACATCATGA TGAAAGTGGT AAAGGGCCAC 
CGCCCAGAGC TGCCACCCAT CTGCAGACCC CGGCCGCGTG CCTGTGCCAG CCTGATAGGG 
CTCATGCAAC GGTGCTGGCA TGCAGACCCA CAGGTGCGGC CCACCTTCCA AGAAATTACC 
TCTGAAACAG AAGACCTTTG TGAGAAGCCT GATGAGGAGG TGAAAGACCT GGCTCATGAG 
CCAGGCGAGA AAAGCTCTCT AGAGTCCAAG AGTGAGGCCA GGCCCGAGTC CTCACGCCTC 
AAGCGCGCCT CTGCTCCCCC CTTCGATAAC GACTGCAGTC TCTCCGAGTT GCTGTCACAG 
TTGGACTCTG GGATCTCCCA GACTCTTGAA GGCCCCGAAG AGCTCAGCCG AAGTTCCTCT 
GAATGCAAGC TCCCATCGTC CAGCAGTGGC AAGAGGCTCT CGGGGGTGTC CTCAGTGGAC 
TCAGCCTTTT CCTCCAGAGG ATCGCTGTCA CTGTCTTTTG AGCGGGAAGC TTCAACAGGC 
GACCTGGGCC CCACAGACAT CCAGAAGAAG AAGCTAGTGG ATGCCATCAT ATCAGGGGAC 
ACCAGCAGGC TGATGAAGAT CCTACAGCCC CAAGATGTGG ACTTGGTTCT AGACAGCAGT 
GCCAGCCTGC TGCACCTGGC TGTGGAGGCC GGACAGGAGG AGTGTGTCAA GTGGCTGCTG 
CTTAACAATG CCAACCCCAA CCTGACCAAC AGGAAGGGCT CTACACCACT GCATATGGCT 
GTGGAGCGGA AGGGACGTGG AATTGTGGAG CTACTGCTAG CCCGGAAGAC CAGTGTCAAT 
GCCAAGGATG AAGACCAGTG GACTGCCCTG CACTTTGCAG CCCAGAATGG GGATGAGGCC 
AGCACAAGGC TGCTGCTAGA GAAGAATGCT TCTGTCAATG AGGTGGACTT TGAGGGCCGA 
ACACCCATGC ATGTAGCCTG CCAGCATGGA CAGGAGAACA TTGTGCGCAC CCTGCTCCGC 
CGTGGTGTGG ATGTGGGCCT GCAGGGAAAG GATGCCTGGT TGCCTCTGCA CTATGCTGCC 
TGGCAGGGCC ACCTTCCCAT TGTTAAGCTG CTAGCCAAGC AGCCTGGGGT GAGTGTGAAT 
GCCCAGACAC TAGACGGGAG GACACCCCTG CACCTGGCTG CTCAGAGGGG GCATTACCGT 
GTGGCTCGCA TTCTCATTGA CCTGTGCTCT GATGTTAACA TCTGCAGCCT ACAGGCACAG 
ACACCTCTGC ATGTTGCTGC AGAGACTGGA CACACTAGTA CTGCCAGGCT ACTCTTGCAT 
CGTGGTGCTG GCAAGGAGGC TTTGACCTCA GAGGGCTATA CTGCCTTGCA CCTGGCAGCC 
CAGAATGGAC ACCTGGCTAC TGTCAAGCTG CTCATAGAGG AGAAGGCTGA TGTGATGGCT 
CGGGGTCCCC TGAATCAGAC AGCACTGCAC CTGGCTGCTG CCCGTGGACA CTCAGAGGTG 
GTAGAAGAGC TGGTCAGTGC TGACCTCATT GACCTGTCTG ATGAGCAGGG CCTCAGCGCA 
CTGCACCTGG CTGCTCAGGG CAGGCATTCA CAGACTGTGG AGACACTGCT CAAACATGGA 
GCACACATCA ACTTGCAGAG TCTCAAGTTC CAAGGAGGCC AGAGCTCTGC TGCCACGTTG 
CTCCGACGCA GCAAGACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ripk4 ( XM_011246154.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244456.1 Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), transcript variant X1, mRNA.

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CloneID	OMu70903
Clone ID Related Accession (Same CDS sequence)	XM_011246154.2
Accession Version	XM_011246154.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	receptor-interacting serine/threonine-protein kinase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246154.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCC TGGAGGAAGC TAAGAAGATG GAGATGGCCA AGTTCCGATA CATTCTACCT 
GTGTACGGCA TATGCCAGGA ACCTGTCGGC TTGGTCATGG AGTACATGGA GACAGGCTCC 
CTGGAGAAGC TGCTGGCCTC AGAGCCATTG CCTTGGGACC TGCGCTTTCG CATCGTGCAC 
GAGACAGCCG TGGGCATGAA CTTCCTGCAT TGCATGTCTC CGCCACTGCT GCACCTAGAC 
CTGAAGCCAG CGAACATCCT GCTGGATGCC CACTACCATG TCAAGATTTC TGACTTTGGG 
CTGGCCAAGT GCAATGGCAT GTCCCACTCT CATGACCTCA GCATGGATGG CCTGTTTGGT 
ACAATCGCTT ACCTCCCTCC AGAGCGAATT CGTGAGAAGA GCCGCTTGTT TGACACCAAA 
CATGATGTAT ACAGCTTCGC CATTGTGATC TGGGGTGTGC TTACACAGAA GAAGCCATTT 
GCAGATGAAA AGAACATCCT ACACATCATG ATGAAAGTGG TAAAGGGCCA CCGCCCAGAG 
CTGCCACCCA TCTGCAGACC CCGGCCGCGT GCCTGTGCCA GCCTGATAGG GCTCATGCAA 
CGGTGCTGGC ATGCAGACCC ACAGGTGCGG CCCACCTTCC AAGAAATTAC CTCTGAAACA 
GAAGACCTTT GTGAGAAGCC TGATGAGGAG GTGAAAGACC TGGCTCATGA GCCAGGCGAG 
AAAAGCTCTC TAGAGTCCAA GAGTGAGGCC AGGCCCGAGT CCTCACGCCT CAAGCGCGCC 
TCTGCTCCCC CCTTCGATAA CGACTGCAGT CTCTCCGAGT TGCTGTCACA GTTGGACTCT 
GGGATCTCCC AGACTCTTGA AGGCCCCGAA GAGCTCAGCC GAAGTTCCTC TGAATGCAAG 
CTCCCATCGT CCAGCAGTGG CAAGAGGCTC TCGGGGGTGT CCTCAGTGGA CTCAGCCTTT 
TCCTCCAGAG GATCGCTGTC ACTGTCTTTT GAGCGGGAAG CTTCAACAGG CGACCTGGGC 
CCCACAGACA TCCAGAAGAA GAAGCTAGTG GATGCCATCA TATCAGGGGA CACCAGCAGG 
CTGATGAAGA TCCTACAGCC CCAAGATGTG GACTTGGTTC TAGACAGCAG TGCCAGCCTG 
CTGCACCTGG CTGTGGAGGC CGGACAGGAG GAGTGTGTCA AGTGGCTGCT GCTTAACAAT 
GCCAACCCCA ACCTGACCAA CAGGAAGGGC TCTACACCAC TGCATATGGC TGTGGAGCGG 
AAGGGACGTG GAATTGTGGA GCTACTGCTA GCCCGGAAGA CCAGTGTCAA TGCCAAGGAT 
GAAGACCAGT GGACTGCCCT GCACTTTGCA GCCCAGAATG GGGATGAGGC CAGCACAAGG 
CTGCTGCTAG AGAAGAATGC TTCTGTCAAT GAGGTGGACT TTGAGGGCCG AACACCCATG 
CATGTAGCCT GCCAGCATGG ACAGGAGAAC ATTGTGCGCA CCCTGCTCCG CCGTGGTGTG 
GATGTGGGCC TGCAGGGAAA GGATGCCTGG TTGCCTCTGC ACTATGCTGC CTGGCAGGGC 
CACCTTCCCA TTGTTAAGCT GCTAGCCAAG CAGCCTGGGG TGAGTGTGAA TGCCCAGACA 
CTAGACGGGA GGACACCCCT GCACCTGGCT GCTCAGAGGG GGCATTACCG TGTGGCTCGC 
ATTCTCATTG ACCTGTGCTC TGATGTTAAC ATCTGCAGCC TACAGGCACA GACACCTCTG 
CATGTTGCTG CAGAGACTGG ACACACTAGT ACTGCCAGGC TACTCTTGCA TCGTGGTGCT 
GGCAAGGAGG CTTTGACCTC AGAGGGCTAT ACTGCCTTGC ACCTGGCAGC CCAGAATGGA 
CACCTGGCTA CTGTCAAGCT GCTCATAGAG GAGAAGGCTG ATGTGATGGC TCGGGGTCCC 
CTGAATCAGA CAGCACTGCA CCTGGCTGCT GCCCGTGGAC ACTCAGAGGT GGTAGAAGAG 
CTGGTCAGTG CTGACCTCAT TGACCTGTCT GATGAGCAGG GCCTCAGCGC ACTGCACCTG 
GCTGCTCAGG GCAGGCATTC ACAGACTGTG GAGACACTGC TCAAACATGG AGCACACATC 
AACTTGCAGA GTCTCAAGTT CCAAGGAGGC CAGAGCTCTG CTGCCACGTT GCTCCGACGC 
AGCAAGACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244456.1
CDS	413..2584
Translation	MELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEKPDEEVKDLAHEPGEKSSLESKSEARPESSRLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIISGDTSRLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAAQNGHLATVKLLIEEKADVMARGPLNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVETLLKHGAHINLQSLKFQGGQSSAATLLRRSKT

Target ORF information:

RefSeq Version	XM_011246154.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus receptor-interacting serine-threonine kinase 4 (Ripk4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246154.2

ORF Insert Sequence:

ATGGAGCTCC TGGAGGAAGC TAAGAAGATG GAGATGGCCA AGTTCCGATA CATTCTACCT 
GTGTACGGCA TATGCCAGGA ACCTGTCGGC TTGGTCATGG AGTACATGGA GACAGGCTCC 
CTGGAGAAGC TGCTGGCCTC AGAGCCATTG CCTTGGGACC TGCGCTTTCG CATCGTGCAC 
GAGACAGCCG TGGGCATGAA CTTCCTGCAT TGCATGTCTC CGCCACTGCT GCACCTAGAC 
CTGAAGCCAG CGAACATCCT GCTGGATGCC CACTACCATG TCAAGATTTC TGACTTTGGG 
CTGGCCAAGT GCAATGGCAT GTCCCACTCT CATGACCTCA GCATGGATGG CCTGTTTGGT 
ACAATCGCTT ACCTCCCTCC AGAGCGAATT CGTGAGAAGA GCCGCTTGTT TGACACCAAA 
CATGATGTAT ACAGCTTCGC CATTGTGATC TGGGGTGTGC TTACACAGAA GAAGCCATTT 
GCAGATGAAA AGAACATCCT ACACATCATG ATGAAAGTGG TAAAGGGCCA CCGCCCAGAG 
CTGCCACCCA TCTGCAGACC CCGGCCGCGT GCCTGTGCCA GCCTGATAGG GCTCATGCAA 
CGGTGCTGGC ATGCAGACCC ACAGGTGCGG CCCACCTTCC AAGAAATTAC CTCTGAAACA 
GAAGACCTTT GTGAGAAGCC TGATGAGGAG GTGAAAGACC TGGCTCATGA GCCAGGCGAG 
AAAAGCTCTC TAGAGTCCAA GAGTGAGGCC AGGCCCGAGT CCTCACGCCT CAAGCGCGCC 
TCTGCTCCCC CCTTCGATAA CGACTGCAGT CTCTCCGAGT TGCTGTCACA GTTGGACTCT 
GGGATCTCCC AGACTCTTGA AGGCCCCGAA GAGCTCAGCC GAAGTTCCTC TGAATGCAAG 
CTCCCATCGT CCAGCAGTGG CAAGAGGCTC TCGGGGGTGT CCTCAGTGGA CTCAGCCTTT 
TCCTCCAGAG GATCGCTGTC ACTGTCTTTT GAGCGGGAAG CTTCAACAGG CGACCTGGGC 
CCCACAGACA TCCAGAAGAA GAAGCTAGTG GATGCCATCA TATCAGGGGA CACCAGCAGG 
CTGATGAAGA TCCTACAGCC CCAAGATGTG GACTTGGTTC TAGACAGCAG TGCCAGCCTG 
CTGCACCTGG CTGTGGAGGC CGGACAGGAG GAGTGTGTCA AGTGGCTGCT GCTTAACAAT 
GCCAACCCCA ACCTGACCAA CAGGAAGGGC TCTACACCAC TGCATATGGC TGTGGAGCGG 
AAGGGACGTG GAATTGTGGA GCTACTGCTA GCCCGGAAGA CCAGTGTCAA TGCCAAGGAT 
GAAGACCAGT GGACTGCCCT GCACTTTGCA GCCCAGAATG GGGATGAGGC CAGCACAAGG 
CTGCTGCTAG AGAAGAATGC TTCTGTCAAT GAGGTGGACT TTGAGGGCCG AACACCCATG 
CATGTAGCCT GCCAGCATGG ACAGGAGAAC ATTGTGCGCA CCCTGCTCCG CCGTGGTGTG 
GATGTGGGCC TGCAGGGAAA GGATGCCTGG TTGCCTCTGC ACTATGCTGC CTGGCAGGGC 
CACCTTCCCA TTGTTAAGCT GCTAGCCAAG CAGCCTGGGG TGAGTGTGAA TGCCCAGACA 
CTAGACGGGA GGACACCCCT GCACCTGGCT GCTCAGAGGG GGCATTACCG TGTGGCTCGC 
ATTCTCATTG ACCTGTGCTC TGATGTTAAC ATCTGCAGCC TACAGGCACA GACACCTCTG 
CATGTTGCTG CAGAGACTGG ACACACTAGT ACTGCCAGGC TACTCTTGCA TCGTGGTGCT 
GGCAAGGAGG CTTTGACCTC AGAGGGCTAT ACTGCCTTGC ACCTGGCAGC CCAGAATGGA 
CACCTGGCTA CTGTCAAGCT GCTCATAGAG GAGAAGGCTG ATGTGATGGC TCGGGGTCCC 
CTGAATCAGA CAGCACTGCA CCTGGCTGCT GCCCGTGGAC ACTCAGAGGT GGTAGAAGAG 
CTGGTCAGTG CTGACCTCAT TGACCTGTCT GATGAGCAGG GCCTCAGCGC ACTGCACCTG 
GCTGCTCAGG GCAGGCATTC ACAGACTGTG GAGACACTGC TCAAACATGG AGCACACATC 
AACTTGCAGA GTCTCAAGTT CCAAGGAGGC CAGAGCTCTG CTGCCACGTT GCTCCGACGC 
AGCAAGACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation.
The Journal of investigative dermatology(2018 Jan)
Urwyler-R?sselet C,Tanghe G,Leurs K,Gilbert B,De Rycke R,De Bruyne M,Lippens S,Bartunkova S,De Groote P,Niessen C,Haftek M,Vandenabeele P,Declercq W

PKK Deletion in Basal Keratinocytes Promotes Tumorigenesis After Chemical Carcinogenesis.
Carcinogenesis(2017 Nov)
Chen L,Hayden MS,Gilmore ES,Alexander-Savino C,Oleksyn D,Gillespie K,Zhao J,Poligone B

Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
The EMBO journal36(13)1963-1980(2017 07)
Lee P,Jiang S,Li Y,Yue J,Gou X,Chen SY,Zhao Y,Schober M,Tan M,Wu X

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Ripk4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

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