Tmprss6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmprss6
Entrez Gene ID	71753
Full Name	transmembrane serine protease 6
Synonyms	1300008A22Rik
General protein information	Preferred Names transmembrane serine protease 6 Names transmembrane protease serine 6 matriptase 2 transmembrane protease, serine 6 type II transmembrane serine protease 6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 E1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006521417.2	XP_006521480.1	transmembrane protease serine 6 isoform X2
XM_006521417.3	XP_006521480.1	transmembrane protease serine 6 isoform X1
NM_001355601.1	NP_001342530.1	transmembrane protease serine 6 isoform 2
XM_006521416.2	XP_006521479.1	transmembrane protease serine 6 isoform X1
NM_027902.2	NP_082178.2	transmembrane protease serine 6 isoform 1

Pathways from BioSystems

Homologies

	TMPRSS6	XP_001085203.1
Mus musculus (house mouse)	Tmprss6	NP_082178.2
Gallus gallus (chicken)	TMPRSS6	XP_004937823.1
Homo sapiens (human)	TMPRSS6	NP_001275929.1
Pan troglodytes (chimpanzee)	TMPRSS6	XP_003317294.2
Bos taurus (cattle)	TMPRSS6	XP_002687735.2
Canis lupus familiaris (dog)	TMPRSS6	XP_850550.2
Rattus norvegicus (Norway rat)	Tmprss6	NP_001124028.1
Xenopus tropicalis (tropical clawed frog)	tmprss6	XP_002934284.1

Gene Ontology
Bibliography

Related articles in PubMed

Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.
Fr?dlov? J, Rychtar??kov? Z, Gurieva I, Vokurka M, Truksa J, Krijt J
PloS one12(10)e0186844(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data (including data from studies using knockout mice) suggest that Mt2/Tmprss6 suppresses hepcidin expression in hepatocytes independently of Hjv; Mt2/Tmprss6 cleaves Alk2, Alk3, ActRIIA, Bmpr2, Hfe, and, to a lesser extent, Hjv and Tfr2; thus, Mt2/Tmprss6 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway. (Mt2/Tmprss6 = matriptase-2; Hjv = hemojuvelin)
Title: Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway.

Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 and IL-13, down-regulates matriptase as well as prostasin through phosphorylation of the transcriptional regulator STAT6
Title: Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.

Erythroferrone and matriptase-2 independently regulate hepcidin expression.
Title: Erythroferrone and matriptase-2 independently regulate hepcidin expression.

The results provide support for the interaction between TMPRSS6 and hemojuvelin in vivo; they also suggest that hemojuvelin could be cleaved by another as yet unknown protease in the absence of functional TMPRSS6.
Title: Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.

the function of matriptase-2 is dominant over that of ERFE and is essential in facilitating hepcidin suppression by attenuating the BMP-SMAD signaling.
Title: Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.

The following Tmprss6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmprss6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu51601	NM_001355601.1 Latest version!	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OMu51601	XM_006521416.2 Latest version!	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OMu16760	NM_027902.2 Latest version!	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
OMu51602	XM_006521417.3 Latest version!	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu51602	XM_006521417.2	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmprss6 ( NM_001355601.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342530.1 Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu51601
Clone ID Related Accession (Same CDS sequence)	NM_001355601.1 , XM_006521416.2
Accession Version	NM_001355601.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2400bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL590144.10. On Sep 21, 2017 this sequence version replaced XM_006521416.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGCCCACCA CCGAGGTCCC CCAAGCGGCT GATGGTCAGG GCGATGCGGG TGATGGAGAG 
GAAGCTGCTG AGCCAGAGGG GAAGTTCAAG CCCCCAAAAA ACACCAAGAG AAAAAACCGG 
GACTACGTCC GCTTCACGCC ACTGTTGCTG GTCTTGGCTG CGCTGGTCTC AGCAGGGGTC 
ATGCTTTGGT ATTTCCTAGG GTACAAAGCG GAAGTGACCG TAAGCCAGGT GTACTCTGGC 
AGCCTCCGGG TGCTCAACCG TCATTTCTCC CAGGACCTGG GCCGACGGGA GTCTATTGCT 
TTCCGCAGTG AATCTGCCAA AGCCCAGAAG ATGCTCCAAG AACTGGTTGC CAGCACCCGC 
CTGGGTACTT ACTACAACTC TAGTTCTGTC TACTCCTTTG GGGAGGGACC CCTCACCTGC 
TTCTTCTGGT TTATCCTTGA CATCCCTGAG TACCAGCGAC TGACCCTGAG CCCTGAAGTA 
GTGCGCGAGC TCCTGGTGGA TGAGCTACTG TCCAACAGCT CAACCCTGGC TTCCTATAAG 
ACCGAATATG AGGTGGACCC GGAAGGCCTG GTGATCCTGG AAGCCAGTGT GAACGACATA 
GTCGTACTGA ATTCCACGCT GGGCTGTTAT CGCTACAGCT ATGTGAACCC AGGCCAGGTC 
CTCCCATTGA AGGGGCCTGA CCAGCAGACC ACAAGCTGCC TGTGGCATCT GCAAGGGCCC 
GAAGACCTCA TGATCAAAGT GCGGCTGGAG TGGACCCGGG TCGATTGCAG AGACAGGGTG 
GCGATGTACG ACGCAGCTGG GCCCCTGGAG AAGAGACTTA TCACCTCGGT CTATGGGTGC 
AGCCGCCAGG AACCTGTGAT GGAGGTGCTG GCATCGGGCT CCGTCATGGC CGTGGTGTGG 
AAAAAGGGCA TGCATAGCTA CTATGACCCT TTCCTGCTCT CAGTGAAGTC TGTGGCCTTC 
CAGGACTGCC AGGTGAACCT GACACTGGAG GGCCGGCTGG ACACACAGGG CTTCCTCCGT 
ACACCCTACT ACCCCAGTTA CTACTCTCCC AGTACCCACT GCTCCTGGCA TCTCACGGTA 
CCCTCTCTGG ACTACGGCTT GGCGCTCTGG TTCGATGCCT ACGCACTGAG GAGGCAGAAG 
TACAACCGAC TGTGTACTCA GGGCCAGTGG ATGATCCAGA ACAGGAGGCT GTGTGGCTTC 
CGTACCCTGC AGCCATATGC TGAGAGGATC CCCATGGTGG CCTCAGATGG TGTCACCATC 
AACTTCACCT CCCAGATCTC CCTCACAGGC CCGGGTGTGC AAGTGTACTA CAGCTTGTAC 
AACCAATCAG ACCCCTGCCC TGGTGAGTTC CTCTGCTCTG TGAATGGACT GTGTGTCCCT 
GCGTGTGACG GGATCAAGGA CTGCCCCAAT GGCCTGGATG AGAGAAACTG TGTCTGCAGA 
GCCATGTTCC AGTGCCAAGA GGACAGCACG TGCATTTCAC TGCCTAGAGT CTGTGACCGG 
CAGCCCGACT GTCTCAATGG CAGTGACGAA GAACAGTGCC AAGAAGGAGT GCCCTGTGGG 
ACATTCACTT TCCAGTGTGA GGACCGGAGC TGTGTGAAGA AGCCCAACCC AGAGTGTGAC 
GGCCAGTCAG ATTGCAGAGA CGGCTCAGAT GAGCAACACT GTGACTGTGG CCTCCAGGGC 
CTCTCCAGCC GTATTGTGGG CGGGACCGTG TCCTCCGAGG GTGAGTGGCC ATGGCAGGCC 
AGCCTCCAGA TTCGGGGTCG ACACATCTGT GGGGGGGCTC TCATCGCTGA CCGCTGGGTC 
ATAACGGCCG CCCACTGCTT CCAGGAGGAC AGCATGGCCT CCCCGAAGCT GTGGACCGTG 
TTCCTGGGAA AGATGCGGCA GAACTCGCGC TGGCCAGGCG AGGTGTCCTT CAAGGTGAGC 
CGTCTGTTCC TGCACCCGTA CCACGAGGAG GACAGCCATG ACTACGACGT GGCCCTGCTG 
CAGCTCGACC ACCCCGTGGT GTACTCGGCC ACTGTGCGCC CCGTCTGCCT GCCTGCCCGC 
TCCCACTTCT TTGAGCCAGG CCAGCACTGC TGGATCACAG GCTGGGGAGC CCAGCGAGAG 
GGTGGTCCGG TGAGCAACAC CCTGCAGAAG GTGGACGTAC AGCTGGTCCC TCAGGACCTC 
TGCAGTGAGG CCTACCGCTA CCAGGTGTCC CCACGCATGC TCTGTGCTGG CTACCGCAAG 
GGCAAGAAAG ATGCCTGCCA GGGTGACTCT GGAGGCCCAC TGGTTTGCAG GGAGCCCAGT 
GGCCGCTGGT TCCTGGCAGG GTTGGTTAGC TGGGGCCTGG GCTGTGGCCG ACCCAATTTC 
TTTGGCGTCT ACACCCGTGT CACACGTGTG ATCAACTGGA TCCAGCAGGT GCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342530.1
CDS	211..2610
Translation	MPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILEASVNDIVVLNSTLGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Target ORF information:

RefSeq Version	NM_001355601.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355601.1

ORF Insert Sequence:

ATGCCCACCA CCGAGGTCCC CCAAGCGGCT GATGGTCAGG GCGATGCGGG TGATGGAGAG 
GAAGCTGCTG AGCCAGAGGG GAAGTTCAAG CCCCCAAAAA ACACCAAGAG AAAAAACCGG 
GACTACGTCC GCTTCACGCC ACTGTTGCTG GTCTTGGCTG CGCTGGTCTC AGCAGGGGTC 
ATGCTTTGGT ATTTCCTAGG GTACAAAGCG GAAGTGACCG TAAGCCAGGT GTACTCTGGC 
AGCCTCCGGG TGCTCAACCG TCATTTCTCC CAGGACCTGG GCCGACGGGA GTCTATTGCT 
TTCCGCAGTG AATCTGCCAA AGCCCAGAAG ATGCTCCAAG AACTGGTTGC CAGCACCCGC 
CTGGGTACTT ACTACAACTC TAGTTCTGTC TACTCCTTTG GGGAGGGACC CCTCACCTGC 
TTCTTCTGGT TTATCCTTGA CATCCCTGAG TACCAGCGAC TGACCCTGAG CCCTGAAGTA 
GTGCGCGAGC TCCTGGTGGA TGAGCTACTG TCCAACAGCT CAACCCTGGC TTCCTATAAG 
ACCGAATATG AGGTGGACCC GGAAGGCCTG GTGATCCTGG AAGCCAGTGT GAACGACATA 
GTCGTACTGA ATTCCACGCT GGGCTGTTAT CGCTACAGCT ATGTGAACCC AGGCCAGGTC 
CTCCCATTGA AGGGGCCTGA CCAGCAGACC ACAAGCTGCC TGTGGCATCT GCAAGGGCCC 
GAAGACCTCA TGATCAAAGT GCGGCTGGAG TGGACCCGGG TCGATTGCAG AGACAGGGTG 
GCGATGTACG ACGCAGCTGG GCCCCTGGAG AAGAGACTTA TCACCTCGGT CTATGGGTGC 
AGCCGCCAGG AACCTGTGAT GGAGGTGCTG GCATCGGGCT CCGTCATGGC CGTGGTGTGG 
AAAAAGGGCA TGCATAGCTA CTATGACCCT TTCCTGCTCT CAGTGAAGTC TGTGGCCTTC 
CAGGACTGCC AGGTGAACCT GACACTGGAG GGCCGGCTGG ACACACAGGG CTTCCTCCGT 
ACACCCTACT ACCCCAGTTA CTACTCTCCC AGTACCCACT GCTCCTGGCA TCTCACGGTA 
CCCTCTCTGG ACTACGGCTT GGCGCTCTGG TTCGATGCCT ACGCACTGAG GAGGCAGAAG 
TACAACCGAC TGTGTACTCA GGGCCAGTGG ATGATCCAGA ACAGGAGGCT GTGTGGCTTC 
CGTACCCTGC AGCCATATGC TGAGAGGATC CCCATGGTGG CCTCAGATGG TGTCACCATC 
AACTTCACCT CCCAGATCTC CCTCACAGGC CCGGGTGTGC AAGTGTACTA CAGCTTGTAC 
AACCAATCAG ACCCCTGCCC TGGTGAGTTC CTCTGCTCTG TGAATGGACT GTGTGTCCCT 
GCGTGTGACG GGATCAAGGA CTGCCCCAAT GGCCTGGATG AGAGAAACTG TGTCTGCAGA 
GCCATGTTCC AGTGCCAAGA GGACAGCACG TGCATTTCAC TGCCTAGAGT CTGTGACCGG 
CAGCCCGACT GTCTCAATGG CAGTGACGAA GAACAGTGCC AAGAAGGAGT GCCCTGTGGG 
ACATTCACTT TCCAGTGTGA GGACCGGAGC TGTGTGAAGA AGCCCAACCC AGAGTGTGAC 
GGCCAGTCAG ATTGCAGAGA CGGCTCAGAT GAGCAACACT GTGACTGTGG CCTCCAGGGC 
CTCTCCAGCC GTATTGTGGG CGGGACCGTG TCCTCCGAGG GTGAGTGGCC ATGGCAGGCC 
AGCCTCCAGA TTCGGGGTCG ACACATCTGT GGGGGGGCTC TCATCGCTGA CCGCTGGGTC 
ATAACGGCCG CCCACTGCTT CCAGGAGGAC AGCATGGCCT CCCCGAAGCT GTGGACCGTG 
TTCCTGGGAA AGATGCGGCA GAACTCGCGC TGGCCAGGCG AGGTGTCCTT CAAGGTGAGC 
CGTCTGTTCC TGCACCCGTA CCACGAGGAG GACAGCCATG ACTACGACGT GGCCCTGCTG 
CAGCTCGACC ACCCCGTGGT GTACTCGGCC ACTGTGCGCC CCGTCTGCCT GCCTGCCCGC 
TCCCACTTCT TTGAGCCAGG CCAGCACTGC TGGATCACAG GCTGGGGAGC CCAGCGAGAG 
GGTGGTCCGG TGAGCAACAC CCTGCAGAAG GTGGACGTAC AGCTGGTCCC TCAGGACCTC 
TGCAGTGAGG CCTACCGCTA CCAGGTGTCC CCACGCATGC TCTGTGCTGG CTACCGCAAG 
GGCAAGAAAG ATGCCTGCCA GGGTGACTCT GGAGGCCCAC TGGTTTGCAG GGAGCCCAGT 
GGCCGCTGGT TCCTGGCAGG GTTGGTTAGC TGGGGCCTGG GCTGTGGCCG ACCCAATTTC 
TTTGGCGTCT ACACCCGTGT CACACGTGTG ATCAACTGGA TCCAGCAGGT GCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmprss6 ( XM_006521416.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521479.1 Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51601
Clone ID Related Accession (Same CDS sequence)	NM_001355601.1 , XM_006521416.2
Accession Version	XM_006521416.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2400bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	transmembrane protease serine 6 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521416.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCACCA CCGAGGTCCC CCAAGCGGCT GATGGTCAGG GCGATGCGGG TGATGGAGAG 
GAAGCTGCTG AGCCAGAGGG GAAGTTCAAG CCCCCAAAAA ACACCAAGAG AAAAAACCGG 
GACTACGTCC GCTTCACGCC ACTGTTGCTG GTCTTGGCTG CGCTGGTCTC AGCAGGGGTC 
ATGCTTTGGT ATTTCCTAGG GTACAAAGCG GAAGTGACCG TAAGCCAGGT GTACTCTGGC 
AGCCTCCGGG TGCTCAACCG TCATTTCTCC CAGGACCTGG GCCGACGGGA GTCTATTGCT 
TTCCGCAGTG AATCTGCCAA AGCCCAGAAG ATGCTCCAAG AACTGGTTGC CAGCACCCGC 
CTGGGTACTT ACTACAACTC TAGTTCTGTC TACTCCTTTG GGGAGGGACC CCTCACCTGC 
TTCTTCTGGT TTATCCTTGA CATCCCTGAG TACCAGCGAC TGACCCTGAG CCCTGAAGTA 
GTGCGCGAGC TCCTGGTGGA TGAGCTACTG TCCAACAGCT CAACCCTGGC TTCCTATAAG 
ACCGAATATG AGGTGGACCC GGAAGGCCTG GTGATCCTGG AAGCCAGTGT GAACGACATA 
GTCGTACTGA ATTCCACGCT GGGCTGTTAT CGCTACAGCT ATGTGAACCC AGGCCAGGTC 
CTCCCATTGA AGGGGCCTGA CCAGCAGACC ACAAGCTGCC TGTGGCATCT GCAAGGGCCC 
GAAGACCTCA TGATCAAAGT GCGGCTGGAG TGGACCCGGG TCGATTGCAG AGACAGGGTG 
GCGATGTACG ACGCAGCTGG GCCCCTGGAG AAGAGACTTA TCACCTCGGT CTATGGGTGC 
AGCCGCCAGG AACCTGTGAT GGAGGTGCTG GCATCGGGCT CCGTCATGGC CGTGGTGTGG 
AAAAAGGGCA TGCATAGCTA CTATGACCCT TTCCTGCTCT CAGTGAAGTC TGTGGCCTTC 
CAGGACTGCC AGGTGAACCT GACACTGGAG GGCCGGCTGG ACACACAGGG CTTCCTCCGT 
ACACCCTACT ACCCCAGTTA CTACTCTCCC AGTACCCACT GCTCCTGGCA TCTCACGGTA 
CCCTCTCTGG ACTACGGCTT GGCGCTCTGG TTCGATGCCT ACGCACTGAG GAGGCAGAAG 
TACAACCGAC TGTGTACTCA GGGCCAGTGG ATGATCCAGA ACAGGAGGCT GTGTGGCTTC 
CGTACCCTGC AGCCATATGC TGAGAGGATC CCCATGGTGG CCTCAGATGG TGTCACCATC 
AACTTCACCT CCCAGATCTC CCTCACAGGC CCGGGTGTGC AAGTGTACTA CAGCTTGTAC 
AACCAATCAG ACCCCTGCCC TGGTGAGTTC CTCTGCTCTG TGAATGGACT GTGTGTCCCT 
GCGTGTGACG GGATCAAGGA CTGCCCCAAT GGCCTGGATG AGAGAAACTG TGTCTGCAGA 
GCCATGTTCC AGTGCCAAGA GGACAGCACG TGCATTTCAC TGCCTAGAGT CTGTGACCGG 
CAGCCCGACT GTCTCAATGG CAGTGACGAA GAACAGTGCC AAGAAGGAGT GCCCTGTGGG 
ACATTCACTT TCCAGTGTGA GGACCGGAGC TGTGTGAAGA AGCCCAACCC AGAGTGTGAC 
GGCCAGTCAG ATTGCAGAGA CGGCTCAGAT GAGCAACACT GTGACTGTGG CCTCCAGGGC 
CTCTCCAGCC GTATTGTGGG CGGGACCGTG TCCTCCGAGG GTGAGTGGCC ATGGCAGGCC 
AGCCTCCAGA TTCGGGGTCG ACACATCTGT GGGGGGGCTC TCATCGCTGA CCGCTGGGTC 
ATAACGGCCG CCCACTGCTT CCAGGAGGAC AGCATGGCCT CCCCGAAGCT GTGGACCGTG 
TTCCTGGGAA AGATGCGGCA GAACTCGCGC TGGCCAGGCG AGGTGTCCTT CAAGGTGAGC 
CGTCTGTTCC TGCACCCGTA CCACGAGGAG GACAGCCATG ACTACGACGT GGCCCTGCTG 
CAGCTCGACC ACCCCGTGGT GTACTCGGCC ACTGTGCGCC CCGTCTGCCT GCCTGCCCGC 
TCCCACTTCT TTGAGCCAGG CCAGCACTGC TGGATCACAG GCTGGGGAGC CCAGCGAGAG 
GGTGGTCCGG TGAGCAACAC CCTGCAGAAG GTGGACGTAC AGCTGGTCCC TCAGGACCTC 
TGCAGTGAGG CCTACCGCTA CCAGGTGTCC CCACGCATGC TCTGTGCTGG CTACCGCAAG 
GGCAAGAAAG ATGCCTGCCA GGGTGACTCT GGAGGCCCAC TGGTTTGCAG GGAGCCCAGT 
GGCCGCTGGT TCCTGGCAGG GTTGGTTAGC TGGGGCCTGG GCTGTGGCCG ACCCAATTTC 
TTTGGCGTCT ACACCCGTGT CACACGTGTG ATCAACTGGA TCCAGCAGGT GCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521479.1
CDS	760..3159
Translation	MPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILEASVNDIVVLNSTLGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Target ORF information:

RefSeq Version	XM_006521416.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521416.2

ORF Insert Sequence:

ATGCCCACCA CCGAGGTCCC CCAAGCGGCT GATGGTCAGG GCGATGCGGG TGATGGAGAG 
GAAGCTGCTG AGCCAGAGGG GAAGTTCAAG CCCCCAAAAA ACACCAAGAG AAAAAACCGG 
GACTACGTCC GCTTCACGCC ACTGTTGCTG GTCTTGGCTG CGCTGGTCTC AGCAGGGGTC 
ATGCTTTGGT ATTTCCTAGG GTACAAAGCG GAAGTGACCG TAAGCCAGGT GTACTCTGGC 
AGCCTCCGGG TGCTCAACCG TCATTTCTCC CAGGACCTGG GCCGACGGGA GTCTATTGCT 
TTCCGCAGTG AATCTGCCAA AGCCCAGAAG ATGCTCCAAG AACTGGTTGC CAGCACCCGC 
CTGGGTACTT ACTACAACTC TAGTTCTGTC TACTCCTTTG GGGAGGGACC CCTCACCTGC 
TTCTTCTGGT TTATCCTTGA CATCCCTGAG TACCAGCGAC TGACCCTGAG CCCTGAAGTA 
GTGCGCGAGC TCCTGGTGGA TGAGCTACTG TCCAACAGCT CAACCCTGGC TTCCTATAAG 
ACCGAATATG AGGTGGACCC GGAAGGCCTG GTGATCCTGG AAGCCAGTGT GAACGACATA 
GTCGTACTGA ATTCCACGCT GGGCTGTTAT CGCTACAGCT ATGTGAACCC AGGCCAGGTC 
CTCCCATTGA AGGGGCCTGA CCAGCAGACC ACAAGCTGCC TGTGGCATCT GCAAGGGCCC 
GAAGACCTCA TGATCAAAGT GCGGCTGGAG TGGACCCGGG TCGATTGCAG AGACAGGGTG 
GCGATGTACG ACGCAGCTGG GCCCCTGGAG AAGAGACTTA TCACCTCGGT CTATGGGTGC 
AGCCGCCAGG AACCTGTGAT GGAGGTGCTG GCATCGGGCT CCGTCATGGC CGTGGTGTGG 
AAAAAGGGCA TGCATAGCTA CTATGACCCT TTCCTGCTCT CAGTGAAGTC TGTGGCCTTC 
CAGGACTGCC AGGTGAACCT GACACTGGAG GGCCGGCTGG ACACACAGGG CTTCCTCCGT 
ACACCCTACT ACCCCAGTTA CTACTCTCCC AGTACCCACT GCTCCTGGCA TCTCACGGTA 
CCCTCTCTGG ACTACGGCTT GGCGCTCTGG TTCGATGCCT ACGCACTGAG GAGGCAGAAG 
TACAACCGAC TGTGTACTCA GGGCCAGTGG ATGATCCAGA ACAGGAGGCT GTGTGGCTTC 
CGTACCCTGC AGCCATATGC TGAGAGGATC CCCATGGTGG CCTCAGATGG TGTCACCATC 
AACTTCACCT CCCAGATCTC CCTCACAGGC CCGGGTGTGC AAGTGTACTA CAGCTTGTAC 
AACCAATCAG ACCCCTGCCC TGGTGAGTTC CTCTGCTCTG TGAATGGACT GTGTGTCCCT 
GCGTGTGACG GGATCAAGGA CTGCCCCAAT GGCCTGGATG AGAGAAACTG TGTCTGCAGA 
GCCATGTTCC AGTGCCAAGA GGACAGCACG TGCATTTCAC TGCCTAGAGT CTGTGACCGG 
CAGCCCGACT GTCTCAATGG CAGTGACGAA GAACAGTGCC AAGAAGGAGT GCCCTGTGGG 
ACATTCACTT TCCAGTGTGA GGACCGGAGC TGTGTGAAGA AGCCCAACCC AGAGTGTGAC 
GGCCAGTCAG ATTGCAGAGA CGGCTCAGAT GAGCAACACT GTGACTGTGG CCTCCAGGGC 
CTCTCCAGCC GTATTGTGGG CGGGACCGTG TCCTCCGAGG GTGAGTGGCC ATGGCAGGCC 
AGCCTCCAGA TTCGGGGTCG ACACATCTGT GGGGGGGCTC TCATCGCTGA CCGCTGGGTC 
ATAACGGCCG CCCACTGCTT CCAGGAGGAC AGCATGGCCT CCCCGAAGCT GTGGACCGTG 
TTCCTGGGAA AGATGCGGCA GAACTCGCGC TGGCCAGGCG AGGTGTCCTT CAAGGTGAGC 
CGTCTGTTCC TGCACCCGTA CCACGAGGAG GACAGCCATG ACTACGACGT GGCCCTGCTG 
CAGCTCGACC ACCCCGTGGT GTACTCGGCC ACTGTGCGCC CCGTCTGCCT GCCTGCCCGC 
TCCCACTTCT TTGAGCCAGG CCAGCACTGC TGGATCACAG GCTGGGGAGC CCAGCGAGAG 
GGTGGTCCGG TGAGCAACAC CCTGCAGAAG GTGGACGTAC AGCTGGTCCC TCAGGACCTC 
TGCAGTGAGG CCTACCGCTA CCAGGTGTCC CCACGCATGC TCTGTGCTGG CTACCGCAAG 
GGCAAGAAAG ATGCCTGCCA GGGTGACTCT GGAGGCCCAC TGGTTTGCAG GGAGCCCAGT 
GGCCGCTGGT TCCTGGCAGG GTTGGTTAGC TGGGGCCTGG GCTGTGGCCG ACCCAATTTC 
TTTGGCGTCT ACACCCGTGT CACACGTGTG ATCAACTGGA TCCAGCAGGT GCTGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmprss6 ( XM_006521417.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521480.1 Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X2, mRNA.

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CloneID	OMu51602
Clone ID Related Accession (Same CDS sequence)	XM_006521417.2 , XM_006521417.3
Accession Version	XM_006521417.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521417.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGGCTG TTATCGCTAC AGCTATGTGA ACCCAGGCCA GGTCCTCCCA 
TTGAAGGGGC CTGACCAGCA GACCACAAGC TGCCTGTGGC ATCTGCAAGG GCCCGAAGAC 
CTCATGATCA AAGTGCGGCT GGAGTGGACC CGGGTCGATT GCAGAGACAG GGTGGCGATG 
TACGACGCAG CTGGGCCCCT GGAGAAGAGA CTTATCACCT CGGTCTATGG GTGCAGCCGC 
CAGGAACCTG TGATGGAGGT GCTGGCATCG GGCTCCGTCA TGGCCGTGGT GTGGAAAAAG 
GGCATGCATA GCTACTATGA CCCTTTCCTG CTCTCAGTGA AGTCTGTGGC CTTCCAGGAC 
TGCCAGGTGA ACCTGACACT GGAGGGCCGG CTGGACACAC AGGGCTTCCT CCGTACACCC 
TACTACCCCA GTTACTACTC TCCCAGTACC CACTGCTCCT GGCATCTCAC GGTACCCTCT 
CTGGACTACG GCTTGGCGCT CTGGTTCGAT GCCTACGCAC TGAGGAGGCA GAAGTACAAC 
CGACTGTGTA CTCAGGGCCA GTGGATGATC CAGAACAGGA GGCTGTGTGG CTTCCGTACC 
CTGCAGCCAT ATGCTGAGAG GATCCCCATG GTGGCCTCAG ATGGTGTCAC CATCAACTTC 
ACCTCCCAGA TCTCCCTCAC AGGCCCGGGT GTGCAAGTGT ACTACAGCTT GTACAACCAA 
TCAGACCCCT GCCCTGGTGA GTTCCTCTGC TCTGTGAATG GACTGTGTGT CCCTGCGTGT 
GACGGGATCA AGGACTGCCC CAATGGCCTG GATGAGAGAA ACTGTGTCTG CAGAGCCATG 
TTCCAGTGCC AAGAGGACAG CACGTGCATT TCACTGCCTA GAGTCTGTGA CCGGCAGCCC 
GACTGTCTCA ATGGCAGTGA CGAAGAACAG TGCCAAGAAG GAGTGCCCTG TGGGACATTC 
ACTTTCCAGT GTGAGGACCG GAGCTGTGTG AAGAAGCCCA ACCCAGAGTG TGACGGCCAG 
TCAGATTGCA GAGACGGCTC AGATGAGCAA CACTGTGACT GTGGCCTCCA GGGCCTCTCC 
AGCCGTATTG TGGGCGGGAC CGTGTCCTCC GAGGGTGAGT GGCCATGGCA GGCCAGCCTC 
CAGATTCGGG GTCGACACAT CTGTGGGGGG GCTCTCATCG CTGACCGCTG GGTCATAACG 
GCCGCCCACT GCTTCCAGGA GGACAGCATG GCCTCCCCGA AGCTGTGGAC CGTGTTCCTG 
GGAAAGATGC GGCAGAACTC GCGCTGGCCA GGCGAGGTGT CCTTCAAGGT GAGCCGTCTG 
TTCCTGCACC CGTACCACGA GGAGGACAGC CATGACTACG ACGTGGCCCT GCTGCAGCTC 
GACCACCCCG TGGTGTACTC GGCCACTGTG CGCCCCGTCT GCCTGCCTGC CCGCTCCCAC 
TTCTTTGAGC CAGGCCAGCA CTGCTGGATC ACAGGCTGGG GAGCCCAGCG AGAGGGTGGT 
CCGGTGAGCA ACACCCTGCA GAAGGTGGAC GTACAGCTGG TCCCTCAGGA CCTCTGCAGT 
GAGGCCTACC GCTACCAGGT GTCCCCACGC ATGCTCTGTG CTGGCTACCG CAAGGGCAAG 
AAAGATGCCT GCCAGGGTGA CTCTGGAGGC CCACTGGTTT GCAGGGAGCC CAGTGGCCGC 
TGGTTCCTGG CAGGGTTGGT TAGCTGGGGC CTGGGCTGTG GCCGACCCAA TTTCTTTGGC 
GTCTACACCC GTGTCACACG TGTGATCAAC TGGATCCAGC AGGTGCTGAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521480.1
CDS	759..3152
Translation	MPRCFQLPCSTRMPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Target ORF information:

RefSeq Version	XM_006521417.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521417.2

ORF Insert Sequence:

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGGCTG TTATCGCTAC AGCTATGTGA ACCCAGGCCA GGTCCTCCCA 
TTGAAGGGGC CTGACCAGCA GACCACAAGC TGCCTGTGGC ATCTGCAAGG GCCCGAAGAC 
CTCATGATCA AAGTGCGGCT GGAGTGGACC CGGGTCGATT GCAGAGACAG GGTGGCGATG 
TACGACGCAG CTGGGCCCCT GGAGAAGAGA CTTATCACCT CGGTCTATGG GTGCAGCCGC 
CAGGAACCTG TGATGGAGGT GCTGGCATCG GGCTCCGTCA TGGCCGTGGT GTGGAAAAAG 
GGCATGCATA GCTACTATGA CCCTTTCCTG CTCTCAGTGA AGTCTGTGGC CTTCCAGGAC 
TGCCAGGTGA ACCTGACACT GGAGGGCCGG CTGGACACAC AGGGCTTCCT CCGTACACCC 
TACTACCCCA GTTACTACTC TCCCAGTACC CACTGCTCCT GGCATCTCAC GGTACCCTCT 
CTGGACTACG GCTTGGCGCT CTGGTTCGAT GCCTACGCAC TGAGGAGGCA GAAGTACAAC 
CGACTGTGTA CTCAGGGCCA GTGGATGATC CAGAACAGGA GGCTGTGTGG CTTCCGTACC 
CTGCAGCCAT ATGCTGAGAG GATCCCCATG GTGGCCTCAG ATGGTGTCAC CATCAACTTC 
ACCTCCCAGA TCTCCCTCAC AGGCCCGGGT GTGCAAGTGT ACTACAGCTT GTACAACCAA 
TCAGACCCCT GCCCTGGTGA GTTCCTCTGC TCTGTGAATG GACTGTGTGT CCCTGCGTGT 
GACGGGATCA AGGACTGCCC CAATGGCCTG GATGAGAGAA ACTGTGTCTG CAGAGCCATG 
TTCCAGTGCC AAGAGGACAG CACGTGCATT TCACTGCCTA GAGTCTGTGA CCGGCAGCCC 
GACTGTCTCA ATGGCAGTGA CGAAGAACAG TGCCAAGAAG GAGTGCCCTG TGGGACATTC 
ACTTTCCAGT GTGAGGACCG GAGCTGTGTG AAGAAGCCCA ACCCAGAGTG TGACGGCCAG 
TCAGATTGCA GAGACGGCTC AGATGAGCAA CACTGTGACT GTGGCCTCCA GGGCCTCTCC 
AGCCGTATTG TGGGCGGGAC CGTGTCCTCC GAGGGTGAGT GGCCATGGCA GGCCAGCCTC 
CAGATTCGGG GTCGACACAT CTGTGGGGGG GCTCTCATCG CTGACCGCTG GGTCATAACG 
GCCGCCCACT GCTTCCAGGA GGACAGCATG GCCTCCCCGA AGCTGTGGAC CGTGTTCCTG 
GGAAAGATGC GGCAGAACTC GCGCTGGCCA GGCGAGGTGT CCTTCAAGGT GAGCCGTCTG 
TTCCTGCACC CGTACCACGA GGAGGACAGC CATGACTACG ACGTGGCCCT GCTGCAGCTC 
GACCACCCCG TGGTGTACTC GGCCACTGTG CGCCCCGTCT GCCTGCCTGC CCGCTCCCAC 
TTCTTTGAGC CAGGCCAGCA CTGCTGGATC ACAGGCTGGG GAGCCCAGCG AGAGGGTGGT 
CCGGTGAGCA ACACCCTGCA GAAGGTGGAC GTACAGCTGG TCCCTCAGGA CCTCTGCAGT 
GAGGCCTACC GCTACCAGGT GTCCCCACGC ATGCTCTGTG CTGGCTACCG CAAGGGCAAG 
AAAGATGCCT GCCAGGGTGA CTCTGGAGGC CCACTGGTTT GCAGGGAGCC CAGTGGCCGC 
TGGTTCCTGG CAGGGTTGGT TAGCTGGGGC CTGGGCTGTG GCCGACCCAA TTTCTTTGGC 
GTCTACACCC GTGTCACACG TGTGATCAAC TGGATCCAGC AGGTGCTGAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmprss6 ( NM_027902.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082178.2 Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 1, mRNA.

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CloneID	OMu16760
Clone ID Related Accession (Same CDS sequence)	NM_027902.2
Accession Version	NM_027902.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB872026.1 and AY240929.1. On Feb 13, 2007 this sequence version replaced NM_027902.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC029645.1, AK004939.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGAAGC CAGTGTGAAC GACATAGTCG TACTGAATTC CACGCTGGGC 
TGTTATCGCT ACAGCTATGT GAACCCAGGC CAGGTCCTCC CATTGAAGGG GCCTGACCAG 
CAGACCACAA GCTGCCTGTG GCATCTGCAA GGGCCCGAAG ACCTCATGAT CAAAGTGCGG 
CTGGAGTGGA CCCGGGTCGA TTGCAGAGAC AGGGTGGCGA TGTACGACGC AGCTGGGCCC 
CTGGAGAAGA GACTTATCAC CTCGGTCTAT GGGTGCAGCC GCCAGGAACC TGTGATGGAG 
GTGCTGGCAT CGGGCTCCGT CATGGCCGTG GTGTGGAAAA AGGGCATGCA TAGCTACTAT 
GACCCTTTCC TGCTCTCAGT GAAGTCTGTG GCCTTCCAGG ACTGCCAGGT GAACCTGACA 
CTGGAGGGCC GGCTGGACAC ACAGGGCTTC CTCCGTACAC CCTACTACCC CAGTTACTAC 
TCTCCCAGTA CCCACTGCTC CTGGCATCTC ACGGTACCCT CTCTGGACTA CGGCTTGGCG 
CTCTGGTTCG ATGCCTACGC ACTGAGGAGG CAGAAGTACA ACCGACTGTG TACTCAGGGC 
CAGTGGATGA TCCAGAACAG GAGGCTGTGT GGCTTCCGTA CCCTGCAGCC ATATGCTGAG 
AGGATCCCCA TGGTGGCCTC AGATGGTGTC ACCATCAACT TCACCTCCCA GATCTCCCTC 
ACAGGCCCGG GTGTGCAAGT GTACTACAGC TTGTACAACC AATCAGACCC CTGCCCTGGT 
GAGTTCCTCT GCTCTGTGAA TGGACTGTGT GTCCCTGCGT GTGACGGGAT CAAGGACTGC 
CCCAATGGCC TGGATGAGAG AAACTGTGTC TGCAGAGCCA TGTTCCAGTG CCAAGAGGAC 
AGCACGTGCA TTTCACTGCC TAGAGTCTGT GACCGGCAGC CCGACTGTCT CAATGGCAGT 
GACGAAGAAC AGTGCCAAGA AGGAGTGCCC TGTGGGACAT TCACTTTCCA GTGTGAGGAC 
CGGAGCTGTG TGAAGAAGCC CAACCCAGAG TGTGACGGCC AGTCAGATTG CAGAGACGGC 
TCAGATGAGC AACACTGTGA CTGTGGCCTC CAGGGCCTCT CCAGCCGTAT TGTGGGCGGG 
ACCGTGTCCT CCGAGGGTGA GTGGCCATGG CAGGCCAGCC TCCAGATTCG GGGTCGACAC 
ATCTGTGGGG GGGCTCTCAT CGCTGACCGC TGGGTCATAA CGGCCGCCCA CTGCTTCCAG 
GAGGACAGCA TGGCCTCCCC GAAGCTGTGG ACCGTGTTCC TGGGAAAGAT GCGGCAGAAC 
TCGCGCTGGC CAGGCGAGGT GTCCTTCAAG GTGAGCCGTC TGTTCCTGCA CCCGTACCAC 
GAGGAGGACA GCCATGACTA CGACGTGGCC CTGCTGCAGC TCGACCACCC CGTGGTGTAC 
TCGGCCACTG TGCGCCCCGT CTGCCTGCCT GCCCGCTCCC ACTTCTTTGA GCCAGGCCAG 
CACTGCTGGA TCACAGGCTG GGGAGCCCAG CGAGAGGGTG GTCCGGTGAG CAACACCCTG 
CAGAAGGTGG ACGTACAGCT GGTCCCTCAG GACCTCTGCA GTGAGGCCTA CCGCTACCAG 
GTGTCCCCAC GCATGCTCTG TGCTGGCTAC CGCAAGGGCA AGAAAGATGC CTGCCAGGGT 
GACTCTGGAG GCCCACTGGT TTGCAGGGAG CCCAGTGGCC GCTGGTTCCT GGCAGGGTTG 
GTTAGCTGGG GCCTGGGCTG TGGCCGACCC AATTTCTTTG GCGTCTACAC CCGTGTCACA 
CGTGTGATCA ACTGGATCCA GCAGGTGCTG ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082178.2
CDS	210..2645
Translation	MPRCFQLPCSTRMPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILEASVNDIVVLNSTLGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Target ORF information:

RefSeq Version	NM_027902.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027902.2

ORF Insert Sequence:

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGAAGC CAGTGTGAAC GACATAGTCG TACTGAATTC CACGCTGGGC 
TGTTATCGCT ACAGCTATGT GAACCCAGGC CAGGTCCTCC CATTGAAGGG GCCTGACCAG 
CAGACCACAA GCTGCCTGTG GCATCTGCAA GGGCCCGAAG ACCTCATGAT CAAAGTGCGG 
CTGGAGTGGA CCCGGGTCGA TTGCAGAGAC AGGGTGGCGA TGTACGACGC AGCTGGGCCC 
CTGGAGAAGA GACTTATCAC CTCGGTCTAT GGGTGCAGCC GCCAGGAACC TGTGATGGAG 
GTGCTGGCAT CGGGCTCCGT CATGGCCGTG GTGTGGAAAA AGGGCATGCA TAGCTACTAT 
GACCCTTTCC TGCTCTCAGT GAAGTCTGTG GCCTTCCAGG ACTGCCAGGT GAACCTGACA 
CTGGAGGGCC GGCTGGACAC ACAGGGCTTC CTCCGTACAC CCTACTACCC CAGTTACTAC 
TCTCCCAGTA CCCACTGCTC CTGGCATCTC ACGGTACCCT CTCTGGACTA CGGCTTGGCG 
CTCTGGTTCG ATGCCTACGC ACTGAGGAGG CAGAAGTACA ACCGACTGTG TACTCAGGGC 
CAGTGGATGA TCCAGAACAG GAGGCTGTGT GGCTTCCGTA CCCTGCAGCC ATATGCTGAG 
AGGATCCCCA TGGTGGCCTC AGATGGTGTC ACCATCAACT TCACCTCCCA GATCTCCCTC 
ACAGGCCCGG GTGTGCAAGT GTACTACAGC TTGTACAACC AATCAGACCC CTGCCCTGGT 
GAGTTCCTCT GCTCTGTGAA TGGACTGTGT GTCCCTGCGT GTGACGGGAT CAAGGACTGC 
CCCAATGGCC TGGATGAGAG AAACTGTGTC TGCAGAGCCA TGTTCCAGTG CCAAGAGGAC 
AGCACGTGCA TTTCACTGCC TAGAGTCTGT GACCGGCAGC CCGACTGTCT CAATGGCAGT 
GACGAAGAAC AGTGCCAAGA AGGAGTGCCC TGTGGGACAT TCACTTTCCA GTGTGAGGAC 
CGGAGCTGTG TGAAGAAGCC CAACCCAGAG TGTGACGGCC AGTCAGATTG CAGAGACGGC 
TCAGATGAGC AACACTGTGA CTGTGGCCTC CAGGGCCTCT CCAGCCGTAT TGTGGGCGGG 
ACCGTGTCCT CCGAGGGTGA GTGGCCATGG CAGGCCAGCC TCCAGATTCG GGGTCGACAC 
ATCTGTGGGG GGGCTCTCAT CGCTGACCGC TGGGTCATAA CGGCCGCCCA CTGCTTCCAG 
GAGGACAGCA TGGCCTCCCC GAAGCTGTGG ACCGTGTTCC TGGGAAAGAT GCGGCAGAAC 
TCGCGCTGGC CAGGCGAGGT GTCCTTCAAG GTGAGCCGTC TGTTCCTGCA CCCGTACCAC 
GAGGAGGACA GCCATGACTA CGACGTGGCC CTGCTGCAGC TCGACCACCC CGTGGTGTAC 
TCGGCCACTG TGCGCCCCGT CTGCCTGCCT GCCCGCTCCC ACTTCTTTGA GCCAGGCCAG 
CACTGCTGGA TCACAGGCTG GGGAGCCCAG CGAGAGGGTG GTCCGGTGAG CAACACCCTG 
CAGAAGGTGG ACGTACAGCT GGTCCCTCAG GACCTCTGCA GTGAGGCCTA CCGCTACCAG 
GTGTCCCCAC GCATGCTCTG TGCTGGCTAC CGCAAGGGCA AGAAAGATGC CTGCCAGGGT 
GACTCTGGAG GCCCACTGGT TTGCAGGGAG CCCAGTGGCC GCTGGTTCCT GGCAGGGTTG 
GTTAGCTGGG GCCTGGGCTG TGGCCGACCC AATTTCTTTG GCGTCTACAC CCGTGTCACA 
CGTGTGATCA ACTGGATCCA GCAGGTGCTG ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmprss6 ( XM_006521417.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521480.1 Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51602
Clone ID Related Accession (Same CDS sequence)	XM_006521417.2 , XM_006521417.3
Accession Version	XM_006521417.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521417.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGGCTG TTATCGCTAC AGCTATGTGA ACCCAGGCCA GGTCCTCCCA 
TTGAAGGGGC CTGACCAGCA GACCACAAGC TGCCTGTGGC ATCTGCAAGG GCCCGAAGAC 
CTCATGATCA AAGTGCGGCT GGAGTGGACC CGGGTCGATT GCAGAGACAG GGTGGCGATG 
TACGACGCAG CTGGGCCCCT GGAGAAGAGA CTTATCACCT CGGTCTATGG GTGCAGCCGC 
CAGGAACCTG TGATGGAGGT GCTGGCATCG GGCTCCGTCA TGGCCGTGGT GTGGAAAAAG 
GGCATGCATA GCTACTATGA CCCTTTCCTG CTCTCAGTGA AGTCTGTGGC CTTCCAGGAC 
TGCCAGGTGA ACCTGACACT GGAGGGCCGG CTGGACACAC AGGGCTTCCT CCGTACACCC 
TACTACCCCA GTTACTACTC TCCCAGTACC CACTGCTCCT GGCATCTCAC GGTACCCTCT 
CTGGACTACG GCTTGGCGCT CTGGTTCGAT GCCTACGCAC TGAGGAGGCA GAAGTACAAC 
CGACTGTGTA CTCAGGGCCA GTGGATGATC CAGAACAGGA GGCTGTGTGG CTTCCGTACC 
CTGCAGCCAT ATGCTGAGAG GATCCCCATG GTGGCCTCAG ATGGTGTCAC CATCAACTTC 
ACCTCCCAGA TCTCCCTCAC AGGCCCGGGT GTGCAAGTGT ACTACAGCTT GTACAACCAA 
TCAGACCCCT GCCCTGGTGA GTTCCTCTGC TCTGTGAATG GACTGTGTGT CCCTGCGTGT 
GACGGGATCA AGGACTGCCC CAATGGCCTG GATGAGAGAA ACTGTGTCTG CAGAGCCATG 
TTCCAGTGCC AAGAGGACAG CACGTGCATT TCACTGCCTA GAGTCTGTGA CCGGCAGCCC 
GACTGTCTCA ATGGCAGTGA CGAAGAACAG TGCCAAGAAG GAGTGCCCTG TGGGACATTC 
ACTTTCCAGT GTGAGGACCG GAGCTGTGTG AAGAAGCCCA ACCCAGAGTG TGACGGCCAG 
TCAGATTGCA GAGACGGCTC AGATGAGCAA CACTGTGACT GTGGCCTCCA GGGCCTCTCC 
AGCCGTATTG TGGGCGGGAC CGTGTCCTCC GAGGGTGAGT GGCCATGGCA GGCCAGCCTC 
CAGATTCGGG GTCGACACAT CTGTGGGGGG GCTCTCATCG CTGACCGCTG GGTCATAACG 
GCCGCCCACT GCTTCCAGGA GGACAGCATG GCCTCCCCGA AGCTGTGGAC CGTGTTCCTG 
GGAAAGATGC GGCAGAACTC GCGCTGGCCA GGCGAGGTGT CCTTCAAGGT GAGCCGTCTG 
TTCCTGCACC CGTACCACGA GGAGGACAGC CATGACTACG ACGTGGCCCT GCTGCAGCTC 
GACCACCCCG TGGTGTACTC GGCCACTGTG CGCCCCGTCT GCCTGCCTGC CCGCTCCCAC 
TTCTTTGAGC CAGGCCAGCA CTGCTGGATC ACAGGCTGGG GAGCCCAGCG AGAGGGTGGT 
CCGGTGAGCA ACACCCTGCA GAAGGTGGAC GTACAGCTGG TCCCTCAGGA CCTCTGCAGT 
GAGGCCTACC GCTACCAGGT GTCCCCACGC ATGCTCTGTG CTGGCTACCG CAAGGGCAAG 
AAAGATGCCT GCCAGGGTGA CTCTGGAGGC CCACTGGTTT GCAGGGAGCC CAGTGGCCGC 
TGGTTCCTGG CAGGGTTGGT TAGCTGGGGC CTGGGCTGTG GCCGACCCAA TTTCTTTGGC 
GTCTACACCC GTGTCACACG TGTGATCAAC TGGATCCAGC AGGTGCTGAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521480.1
CDS	224..2617
Translation	MPRCFQLPCSTRMPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Target ORF information:

RefSeq Version	XM_006521417.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521417.3

ORF Insert Sequence:

ATGCCGAGAT GTTTCCAGCT CCCCTGTTCT ACCAGGATGC CCACCACCGA GGTCCCCCAA 
GCGGCTGATG GTCAGGGCGA TGCGGGTGAT GGAGAGGAAG CTGCTGAGCC AGAGGGGAAG 
TTCAAGCCCC CAAAAAACAC CAAGAGAAAA AACCGGGACT ACGTCCGCTT CACGCCACTG 
TTGCTGGTCT TGGCTGCGCT GGTCTCAGCA GGGGTCATGC TTTGGTATTT CCTAGGGTAC 
AAAGCGGAAG TGACCGTAAG CCAGGTGTAC TCTGGCAGCC TCCGGGTGCT CAACCGTCAT 
TTCTCCCAGG ACCTGGGCCG ACGGGAGTCT ATTGCTTTCC GCAGTGAATC TGCCAAAGCC 
CAGAAGATGC TCCAAGAACT GGTTGCCAGC ACCCGCCTGG GTACTTACTA CAACTCTAGT 
TCTGTCTACT CCTTTGGGGA GGGACCCCTC ACCTGCTTCT TCTGGTTTAT CCTTGACATC 
CCTGAGTACC AGCGACTGAC CCTGAGCCCT GAAGTAGTGC GCGAGCTCCT GGTGGATGAG 
CTACTGTCCA ACAGCTCAAC CCTGGCTTCC TATAAGACCG AATATGAGGT GGACCCGGAA 
GGCCTGGTGA TCCTGGGCTG TTATCGCTAC AGCTATGTGA ACCCAGGCCA GGTCCTCCCA 
TTGAAGGGGC CTGACCAGCA GACCACAAGC TGCCTGTGGC ATCTGCAAGG GCCCGAAGAC 
CTCATGATCA AAGTGCGGCT GGAGTGGACC CGGGTCGATT GCAGAGACAG GGTGGCGATG 
TACGACGCAG CTGGGCCCCT GGAGAAGAGA CTTATCACCT CGGTCTATGG GTGCAGCCGC 
CAGGAACCTG TGATGGAGGT GCTGGCATCG GGCTCCGTCA TGGCCGTGGT GTGGAAAAAG 
GGCATGCATA GCTACTATGA CCCTTTCCTG CTCTCAGTGA AGTCTGTGGC CTTCCAGGAC 
TGCCAGGTGA ACCTGACACT GGAGGGCCGG CTGGACACAC AGGGCTTCCT CCGTACACCC 
TACTACCCCA GTTACTACTC TCCCAGTACC CACTGCTCCT GGCATCTCAC GGTACCCTCT 
CTGGACTACG GCTTGGCGCT CTGGTTCGAT GCCTACGCAC TGAGGAGGCA GAAGTACAAC 
CGACTGTGTA CTCAGGGCCA GTGGATGATC CAGAACAGGA GGCTGTGTGG CTTCCGTACC 
CTGCAGCCAT ATGCTGAGAG GATCCCCATG GTGGCCTCAG ATGGTGTCAC CATCAACTTC 
ACCTCCCAGA TCTCCCTCAC AGGCCCGGGT GTGCAAGTGT ACTACAGCTT GTACAACCAA 
TCAGACCCCT GCCCTGGTGA GTTCCTCTGC TCTGTGAATG GACTGTGTGT CCCTGCGTGT 
GACGGGATCA AGGACTGCCC CAATGGCCTG GATGAGAGAA ACTGTGTCTG CAGAGCCATG 
TTCCAGTGCC AAGAGGACAG CACGTGCATT TCACTGCCTA GAGTCTGTGA CCGGCAGCCC 
GACTGTCTCA ATGGCAGTGA CGAAGAACAG TGCCAAGAAG GAGTGCCCTG TGGGACATTC 
ACTTTCCAGT GTGAGGACCG GAGCTGTGTG AAGAAGCCCA ACCCAGAGTG TGACGGCCAG 
TCAGATTGCA GAGACGGCTC AGATGAGCAA CACTGTGACT GTGGCCTCCA GGGCCTCTCC 
AGCCGTATTG TGGGCGGGAC CGTGTCCTCC GAGGGTGAGT GGCCATGGCA GGCCAGCCTC 
CAGATTCGGG GTCGACACAT CTGTGGGGGG GCTCTCATCG CTGACCGCTG GGTCATAACG 
GCCGCCCACT GCTTCCAGGA GGACAGCATG GCCTCCCCGA AGCTGTGGAC CGTGTTCCTG 
GGAAAGATGC GGCAGAACTC GCGCTGGCCA GGCGAGGTGT CCTTCAAGGT GAGCCGTCTG 
TTCCTGCACC CGTACCACGA GGAGGACAGC CATGACTACG ACGTGGCCCT GCTGCAGCTC 
GACCACCCCG TGGTGTACTC GGCCACTGTG CGCCCCGTCT GCCTGCCTGC CCGCTCCCAC 
TTCTTTGAGC CAGGCCAGCA CTGCTGGATC ACAGGCTGGG GAGCCCAGCG AGAGGGTGGT 
CCGGTGAGCA ACACCCTGCA GAAGGTGGAC GTACAGCTGG TCCCTCAGGA CCTCTGCAGT 
GAGGCCTACC GCTACCAGGT GTCCCCACGC ATGCTCTGTG CTGGCTACCG CAAGGGCAAG 
AAAGATGCCT GCCAGGGTGA CTCTGGAGGC CCACTGGTTT GCAGGGAGCC CAGTGGCCGC 
TGGTTCCTGG CAGGGTTGGT TAGCTGGGGC CTGGGCTGTG GCCGACCCAA TTTCTTTGGC 
GTCTACACCC GTGTCACACG TGTGATCAAC TGGATCCAGC AGGTGCTGAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.
PloS one12(10)e0186844(2017)
Fr?dlov? J,Rychtar??kov? Z,Gurieva I,Vokurka M,Truksa J,Krijt J

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Tmprss6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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