Telo2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Telo2
Entrez Gene ID	71718
Full Name	telomere maintenance 2
Synonyms	1200003M09Rik,AI415602,Tel2,mKIAA0683
General protein information	Preferred Names telomere maintenance 2 Names telomere length regulation protein TEL2 homolog TEL2, telomere maintenance 2, homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011246619.2	XP_011244921.1	telomere length regulation protein TEL2 homolog isoform X2
XM_011246619.3	XP_011244921.1	telomere length regulation protein TEL2 homolog isoform X2
XM_017317644.1	XP_017173133.1	telomere length regulation protein TEL2 homolog isoform X1
NM_027880.2	NP_082156.2	telomere length regulation protein TEL2 homolog
NM_001163661.1	NP_001157133.1	telomere length regulation protein TEL2 homolog
XM_011246618.2	XP_011244920.1	telomere length regulation protein TEL2 homolog isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TELO2	NP_057195.2
Bos taurus (cattle)	TELO2	XP_002697960.1
Gallus gallus (chicken)	TELO2	XP_415052.4
Danio rerio (zebrafish)	telo2	NP_001071209.1
Pan troglodytes (chimpanzee)	TELO2	XP_510730.3
Mus musculus (house mouse)	Telo2	NP_001157133.1
Xenopus tropicalis (tropical clawed frog)	telo2	NP_001072876.1
	TELO2	XP_001089282.1
Rattus norvegicus (Norway rat)	Telo2	XP_220236.3
Canis lupus familiaris (dog)	TELO2	XP_547196.4

Gene Ontology
Bibliography

Related articles in PubMed

Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1.
Pal M, Morgan M, Phelps SE, Roe SM, Parry-Morris S, Downs JA, Polier S, Pearl LH, Prodromou C
Structure (London, England : 1993)22(6)805-18(2014 Jun)

Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH
Molecular cell54(1)119-132(2014 Apr)

CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.
Horejs? Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S, Skehel JM, de Lange T, Boulton SJ
Molecular cell39(6)839-50(2010 Sep)

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Takai H, Xie Y, de Lange T, Pavletich NP
Genes & development24(18)2019-30(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IP7, formed by IP6K2, binds CK2 to enhance its phosphorylation of the Tti1/Tel2 complex, thereby stabilizing DNA-PKcs and ATM. This process stimulates p53 phosphorylation at serine 15 to activate the cell death program.
Title: Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.

The CK2 phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase functions and is essential for mTOR and SMG1 stability in vivo.
Title: CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.

Identify Tel2 as a highly conserved regulator of the stability of PI3K-related protein kinases.
Title: Tel2 regulates the stability of PI3K-related protein kinases.

The following Telo2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Telo2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu70732	XM_011246618.2 Latest version!	Mus musculus telomere maintenance 2 (Telo2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu70732	XM_017317644.1 Latest version!	Mus musculus telomere maintenance 2 (Telo2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu04714	NM_001163661.1 Latest version!	Mus musculus telomere maintenance 2 (Telo2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu04714	NM_027880.2 Latest version!	Mus musculus telomere maintenance 2 (Telo2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu70733	XM_011246619.3 Latest version!	Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu70733	XM_011246619.2	Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Telo2 ( XM_017317644.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173133.1 Mus musculus telomere maintenance 2 (Telo2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70732
Clone ID Related Accession (Same CDS sequence)	XM_017317644.1 , XM_011246618.2
Accession Version	XM_017317644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGA GCCTGTTGGG GTACTTGGCT CTAGACAGTC AGCGGCGGCC ACTCCTCATA 
CAGGTGCTTA AGGAGCTGCT GGAGACCTGG GGCTGCAGCA GTGCTGTCCG ACACACACCC 
CTGGAGCAGC AGTGTTACAT CAGCAAGGCC ATCCTTGTCT GCCTGGCACA CCTCGGGGAG 
CCGGAGCTGC AGGACATCCG GGATGAATTG CTGGCCAGCA TGATGGCAGG CGTGAAGTGC 
CGCCTGGATA GCAGCCTGCC CCCTGTGCGC CGCTTGGGCA TGATTGTGGC CGAGGTCATC 
AGCTCCAGGA TCCACCCTGA GGGGCCTCTC CTGAAATTCC AATATGAAGA TGACGAGATG 
AGCCGTGAGT TGCTGGCTTT GGCTACCCCG GAGCCTGCGG GTGACTGCTC CTCGGTGTCA 
CGAGGCCCAT CCCCAGCTCC TGTTGACACA GAGTCTCCTG TAGAGATGCC AGAAAAGGCC 
GTGGAGAGTG ATGTCCCCCC AACTCAGCCT CAGGGCTCTG ACTCGGAGCT GGACAGTGAC 
GATGAGTTCA TCCCCTATGA CATGTCAGGG GACAGAGAGC TGAAGAGCAG CAAGGAGCCC 
CTGTATATCC GAGACTGCGT GGAAGCTTTG ACTACATCTG AGGACATGGA ACGCTGGGAG 
GCGTCCCTAA AGGGGCTTGA GGGCCTGGTA TATAGGAGCC CCACGGCCAC TCGGGAGGTG 
AGTGTGGAGC TGGCCAAAGT GCTACTGCAC CTGGAAGAGA AGACCTGTGT AGCAGAGTTT 
GAGCAGCTGC GCCAGAGCGC TCTGGTAGCT GTTACAGTCA CAGACCCGGA GCAGGTAGCC 
AAGTATCTGA CCTCACAGTT CTATGGCCTA AACTATAGCC TCCGCCAGCG CATGGACATC 
CTGGACGTCC TTGTTCTGGC TGCCCAGGCA CTGTCTCGGC CAAAGAGCCT GCAGAGACGT 
TCCCAGCACG GTCCCCCCGT TCCTGGCACC ATGTGTTCAC CAGCACTAGC CGTTTCTCAG 
ACTGGCAATG TCGCTGCTCC TGACTGGCAG GTGGTTGTGG AGGAGCGGAT CAGAAGCAAG 
ACCCGGAGGT TCTCGAAGGG CTGTCCTCAG CGGGAGCTGT CAGGCGTCCC CAATGAATTC 
AGCTCTGTGG CTGGCTACTT CTTCTTCCCC CTCCTTCAGC ACTTTGACAG GCCTCTGGTG 
ACCTTCGACC TTTTAGGAGA TGATCAGTTG GTACTTGGAA GACTGACCCA CACCTTAGCG 
TCCCTGATGT ACCTGGCTGT TAACACCACA GTGGCTGTGC CTATGGGTAA GGCCCTGCTG 
GAGTTTGTAT GGGCCCTTCG CTTCCACGTT GACATTTACG TGCGCCGGGG CTTGCTGTCT 
GCTGTGTCCT CTGTCCTCCT CAGTGTACCC ACAGAGCGGC TGCTGGGGGA CCTGCCAGAT 
GAGCTACTGG AAGCCAGATC CTGGTTGGCA GATGTGGCTG AGAAGGATGT GGACGAGGAC 
TGTAGGGAGC TGGCAGTAAG GGCTCTGCTG CTTCTGGAGA GACTCAAAGA CAAGCTCCTG 
TCCAGTTCCT CTCCACAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173133.1
CDS	583..2166
Translation	MVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEALTTSEDMERWEASLKGLEGLVYRSPTATREVSVELAKVLLHLEEKTCVAEFEQLRQSALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPKSLQRRSQHGPPVPGTMCSPALAVSQTGNVAAPDWQVVVEERIRSKTRRFSKGCPQRELSGVPNEFSSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAVRALLLLERLKDKLLSSSSPQP

Target ORF information:

RefSeq Version	XM_017317644.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017317644.1

ORF Insert Sequence:

ATGGTGCAGA GCCTGTTGGG GTACTTGGCT CTAGACAGTC AGCGGCGGCC ACTCCTCATA 
CAGGTGCTTA AGGAGCTGCT GGAGACCTGG GGCTGCAGCA GTGCTGTCCG ACACACACCC 
CTGGAGCAGC AGTGTTACAT CAGCAAGGCC ATCCTTGTCT GCCTGGCACA CCTCGGGGAG 
CCGGAGCTGC AGGACATCCG GGATGAATTG CTGGCCAGCA TGATGGCAGG CGTGAAGTGC 
CGCCTGGATA GCAGCCTGCC CCCTGTGCGC CGCTTGGGCA TGATTGTGGC CGAGGTCATC 
AGCTCCAGGA TCCACCCTGA GGGGCCTCTC CTGAAATTCC AATATGAAGA TGACGAGATG 
AGCCGTGAGT TGCTGGCTTT GGCTACCCCG GAGCCTGCGG GTGACTGCTC CTCGGTGTCA 
CGAGGCCCAT CCCCAGCTCC TGTTGACACA GAGTCTCCTG TAGAGATGCC AGAAAAGGCC 
GTGGAGAGTG ATGTCCCCCC AACTCAGCCT CAGGGCTCTG ACTCGGAGCT GGACAGTGAC 
GATGAGTTCA TCCCCTATGA CATGTCAGGG GACAGAGAGC TGAAGAGCAG CAAGGAGCCC 
CTGTATATCC GAGACTGCGT GGAAGCTTTG ACTACATCTG AGGACATGGA ACGCTGGGAG 
GCGTCCCTAA AGGGGCTTGA GGGCCTGGTA TATAGGAGCC CCACGGCCAC TCGGGAGGTG 
AGTGTGGAGC TGGCCAAAGT GCTACTGCAC CTGGAAGAGA AGACCTGTGT AGCAGAGTTT 
GAGCAGCTGC GCCAGAGCGC TCTGGTAGCT GTTACAGTCA CAGACCCGGA GCAGGTAGCC 
AAGTATCTGA CCTCACAGTT CTATGGCCTA AACTATAGCC TCCGCCAGCG CATGGACATC 
CTGGACGTCC TTGTTCTGGC TGCCCAGGCA CTGTCTCGGC CAAAGAGCCT GCAGAGACGT 
TCCCAGCACG GTCCCCCCGT TCCTGGCACC ATGTGTTCAC CAGCACTAGC CGTTTCTCAG 
ACTGGCAATG TCGCTGCTCC TGACTGGCAG GTGGTTGTGG AGGAGCGGAT CAGAAGCAAG 
ACCCGGAGGT TCTCGAAGGG CTGTCCTCAG CGGGAGCTGT CAGGCGTCCC CAATGAATTC 
AGCTCTGTGG CTGGCTACTT CTTCTTCCCC CTCCTTCAGC ACTTTGACAG GCCTCTGGTG 
ACCTTCGACC TTTTAGGAGA TGATCAGTTG GTACTTGGAA GACTGACCCA CACCTTAGCG 
TCCCTGATGT ACCTGGCTGT TAACACCACA GTGGCTGTGC CTATGGGTAA GGCCCTGCTG 
GAGTTTGTAT GGGCCCTTCG CTTCCACGTT GACATTTACG TGCGCCGGGG CTTGCTGTCT 
GCTGTGTCCT CTGTCCTCCT CAGTGTACCC ACAGAGCGGC TGCTGGGGGA CCTGCCAGAT 
GAGCTACTGG AAGCCAGATC CTGGTTGGCA GATGTGGCTG AGAAGGATGT GGACGAGGAC 
TGTAGGGAGC TGGCAGTAAG GGCTCTGCTG CTTCTGGAGA GACTCAAAGA CAAGCTCCTG 
TCCAGTTCCT CTCCACAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Telo2 ( XM_011246618.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244920.1 Mus musculus telomere maintenance 2 (Telo2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu70732
Clone ID Related Accession (Same CDS sequence)	XM_017317644.1 , XM_011246618.2
Accession Version	XM_011246618.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246618.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGA GCCTGTTGGG GTACTTGGCT CTAGACAGTC AGCGGCGGCC ACTCCTCATA 
CAGGTGCTTA AGGAGCTGCT GGAGACCTGG GGCTGCAGCA GTGCTGTCCG ACACACACCC 
CTGGAGCAGC AGTGTTACAT CAGCAAGGCC ATCCTTGTCT GCCTGGCACA CCTCGGGGAG 
CCGGAGCTGC AGGACATCCG GGATGAATTG CTGGCCAGCA TGATGGCAGG CGTGAAGTGC 
CGCCTGGATA GCAGCCTGCC CCCTGTGCGC CGCTTGGGCA TGATTGTGGC CGAGGTCATC 
AGCTCCAGGA TCCACCCTGA GGGGCCTCTC CTGAAATTCC AATATGAAGA TGACGAGATG 
AGCCGTGAGT TGCTGGCTTT GGCTACCCCG GAGCCTGCGG GTGACTGCTC CTCGGTGTCA 
CGAGGCCCAT CCCCAGCTCC TGTTGACACA GAGTCTCCTG TAGAGATGCC AGAAAAGGCC 
GTGGAGAGTG ATGTCCCCCC AACTCAGCCT CAGGGCTCTG ACTCGGAGCT GGACAGTGAC 
GATGAGTTCA TCCCCTATGA CATGTCAGGG GACAGAGAGC TGAAGAGCAG CAAGGAGCCC 
CTGTATATCC GAGACTGCGT GGAAGCTTTG ACTACATCTG AGGACATGGA ACGCTGGGAG 
GCGTCCCTAA AGGGGCTTGA GGGCCTGGTA TATAGGAGCC CCACGGCCAC TCGGGAGGTG 
AGTGTGGAGC TGGCCAAAGT GCTACTGCAC CTGGAAGAGA AGACCTGTGT AGCAGAGTTT 
GAGCAGCTGC GCCAGAGCGC TCTGGTAGCT GTTACAGTCA CAGACCCGGA GCAGGTAGCC 
AAGTATCTGA CCTCACAGTT CTATGGCCTA AACTATAGCC TCCGCCAGCG CATGGACATC 
CTGGACGTCC TTGTTCTGGC TGCCCAGGCA CTGTCTCGGC CAAAGAGCCT GCAGAGACGT 
TCCCAGCACG GTCCCCCCGT TCCTGGCACC ATGTGTTCAC CAGCACTAGC CGTTTCTCAG 
ACTGGCAATG TCGCTGCTCC TGACTGGCAG GTGGTTGTGG AGGAGCGGAT CAGAAGCAAG 
ACCCGGAGGT TCTCGAAGGG CTGTCCTCAG CGGGAGCTGT CAGGCGTCCC CAATGAATTC 
AGCTCTGTGG CTGGCTACTT CTTCTTCCCC CTCCTTCAGC ACTTTGACAG GCCTCTGGTG 
ACCTTCGACC TTTTAGGAGA TGATCAGTTG GTACTTGGAA GACTGACCCA CACCTTAGCG 
TCCCTGATGT ACCTGGCTGT TAACACCACA GTGGCTGTGC CTATGGGTAA GGCCCTGCTG 
GAGTTTGTAT GGGCCCTTCG CTTCCACGTT GACATTTACG TGCGCCGGGG CTTGCTGTCT 
GCTGTGTCCT CTGTCCTCCT CAGTGTACCC ACAGAGCGGC TGCTGGGGGA CCTGCCAGAT 
GAGCTACTGG AAGCCAGATC CTGGTTGGCA GATGTGGCTG AGAAGGATGT GGACGAGGAC 
TGTAGGGAGC TGGCAGTAAG GGCTCTGCTG CTTCTGGAGA GACTCAAAGA CAAGCTCCTG 
TCCAGTTCCT CTCCACAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244920.1
CDS	302..1885
Translation	MVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEALTTSEDMERWEASLKGLEGLVYRSPTATREVSVELAKVLLHLEEKTCVAEFEQLRQSALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPKSLQRRSQHGPPVPGTMCSPALAVSQTGNVAAPDWQVVVEERIRSKTRRFSKGCPQRELSGVPNEFSSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAVRALLLLERLKDKLLSSSSPQP

Target ORF information:

RefSeq Version	XM_011246618.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246618.2

ORF Insert Sequence:

ATGGTGCAGA GCCTGTTGGG GTACTTGGCT CTAGACAGTC AGCGGCGGCC ACTCCTCATA 
CAGGTGCTTA AGGAGCTGCT GGAGACCTGG GGCTGCAGCA GTGCTGTCCG ACACACACCC 
CTGGAGCAGC AGTGTTACAT CAGCAAGGCC ATCCTTGTCT GCCTGGCACA CCTCGGGGAG 
CCGGAGCTGC AGGACATCCG GGATGAATTG CTGGCCAGCA TGATGGCAGG CGTGAAGTGC 
CGCCTGGATA GCAGCCTGCC CCCTGTGCGC CGCTTGGGCA TGATTGTGGC CGAGGTCATC 
AGCTCCAGGA TCCACCCTGA GGGGCCTCTC CTGAAATTCC AATATGAAGA TGACGAGATG 
AGCCGTGAGT TGCTGGCTTT GGCTACCCCG GAGCCTGCGG GTGACTGCTC CTCGGTGTCA 
CGAGGCCCAT CCCCAGCTCC TGTTGACACA GAGTCTCCTG TAGAGATGCC AGAAAAGGCC 
GTGGAGAGTG ATGTCCCCCC AACTCAGCCT CAGGGCTCTG ACTCGGAGCT GGACAGTGAC 
GATGAGTTCA TCCCCTATGA CATGTCAGGG GACAGAGAGC TGAAGAGCAG CAAGGAGCCC 
CTGTATATCC GAGACTGCGT GGAAGCTTTG ACTACATCTG AGGACATGGA ACGCTGGGAG 
GCGTCCCTAA AGGGGCTTGA GGGCCTGGTA TATAGGAGCC CCACGGCCAC TCGGGAGGTG 
AGTGTGGAGC TGGCCAAAGT GCTACTGCAC CTGGAAGAGA AGACCTGTGT AGCAGAGTTT 
GAGCAGCTGC GCCAGAGCGC TCTGGTAGCT GTTACAGTCA CAGACCCGGA GCAGGTAGCC 
AAGTATCTGA CCTCACAGTT CTATGGCCTA AACTATAGCC TCCGCCAGCG CATGGACATC 
CTGGACGTCC TTGTTCTGGC TGCCCAGGCA CTGTCTCGGC CAAAGAGCCT GCAGAGACGT 
TCCCAGCACG GTCCCCCCGT TCCTGGCACC ATGTGTTCAC CAGCACTAGC CGTTTCTCAG 
ACTGGCAATG TCGCTGCTCC TGACTGGCAG GTGGTTGTGG AGGAGCGGAT CAGAAGCAAG 
ACCCGGAGGT TCTCGAAGGG CTGTCCTCAG CGGGAGCTGT CAGGCGTCCC CAATGAATTC 
AGCTCTGTGG CTGGCTACTT CTTCTTCCCC CTCCTTCAGC ACTTTGACAG GCCTCTGGTG 
ACCTTCGACC TTTTAGGAGA TGATCAGTTG GTACTTGGAA GACTGACCCA CACCTTAGCG 
TCCCTGATGT ACCTGGCTGT TAACACCACA GTGGCTGTGC CTATGGGTAA GGCCCTGCTG 
GAGTTTGTAT GGGCCCTTCG CTTCCACGTT GACATTTACG TGCGCCGGGG CTTGCTGTCT 
GCTGTGTCCT CTGTCCTCCT CAGTGTACCC ACAGAGCGGC TGCTGGGGGA CCTGCCAGAT 
GAGCTACTGG AAGCCAGATC CTGGTTGGCA GATGTGGCTG AGAAGGATGT GGACGAGGAC 
TGTAGGGAGC TGGCAGTAAG GGCTCTGCTG CTTCTGGAGA GACTCAAAGA CAAGCTCCTG 
TCCAGTTCCT CTCCACAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Telo2 ( XM_011246619.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244921.1 Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OMu70733
Clone ID Related Accession (Same CDS sequence)	XM_011246619.2 , XM_011246619.3
Accession Version	XM_011246619.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246619.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGGTGGGC TTCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244921.1
CDS	575..2152
Translation	MDPALSAVRLTVQEAIHILSSSEDAGHILSTLGTLKRYLGGTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPGGQLERLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMAQLLDTFLSTGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNCLQRDNLTQFFPQNYFPLLGQEVVQALKAVVNFLQDGLDCSVSFVSRVLGKVCIQGRKREILSVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVVTRKLLLLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEGGLR

Target ORF information:

RefSeq Version	XM_011246619.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246619.2

ORF Insert Sequence:

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGGTGGGC TTCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Telo2 ( NM_027880.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082156.2 Mus musculus telomere maintenance 2 (Telo2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04714
Clone ID Related Accession (Same CDS sequence)	NM_027880.2 , NM_001163661.1
Accession Version	NM_027880.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ560945.1, BB844017.1, AK004582.1, AK146963.1 and BB083455.1. On Aug 8, 2009 this sequence version replaced NM_027880.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK004582.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGCTTTGA CTACATCTGA GGACATGGAA CGCTGGGAGG CGTCCCTAAA GGGGCTTGAG 
GGCCTGGTAT ATAGGAGCCC CACGGCCACT CGGGAGGTGA GTGTGGAGCT GGCCAAAGTG 
CTACTGCACC TGGAAGAGAA GACCTGTGTA GCAGAGTTTG AGCAGCTGCG CCAGAGCGCT 
CTGGTAGCTG TTACAGTCAC AGACCCGGAG CAGGTAGCCA AGTATCTGAC CTCACAGTTC 
TATGGCCTAA ACTATAGCCT CCGCCAGCGC ATGGACATCC TGGACGTCCT TGTTCTGGCT 
GCCCAGGCAC TGTCTCGGCC AAAGAGCCTG CAGAGACGTT CCCAGCACGG TCCCCCCGTT 
CCTGGCACCA TGTGTTCACC AGCACTAGCC GTTTCTCAGA CTGGCAATGT CGCTGCTCCT 
GACTGGCAGG TGGTTGTGGA GGAGCGGATC AGAAGCAAGA CCCGGAGGTT CTCGAAGGGC 
TGTCCTCAGC GGGAGCTGTC AGGCGTCCCC AATGAATTCA GCTCTGTGGC TGGCTACTTC 
TTCTTCCCCC TCCTTCAGCA CTTTGACAGG CCTCTGGTGA CCTTCGACCT TTTAGGAGAT 
GATCAGTTGG TACTTGGAAG ACTGACCCAC ACCTTAGCGT CCCTGATGTA CCTGGCTGTT 
AACACCACAG TGGCTGTGCC TATGGGTAAG GCCCTGCTGG AGTTTGTATG GGCCCTTCGC 
TTCCACGTTG ACATTTACGT GCGCCGGGGC TTGCTGTCTG CTGTGTCCTC TGTCCTCCTC 
AGTGTACCCA CAGAGCGGCT GCTGGGGGAC CTGCCAGATG AGCTACTGGA AGCCAGATCC 
TGGTTGGCAG ATGTGGCTGA GAAGGATGTG GACGAGGACT GTAGGGAGCT GGCAGTAAGG 
GCTCTGCTGC TTCTGGAGAG ACTCAAAGAC AAGCTCCTGT CCAGTTCCTC TCCACAGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082156.2
CDS	481..3003
Translation	MDPALSAVRLTVQEAIHILSSSEDAGHILSTLGTLKRYLGGTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPGGQLERLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMAQLLDTFLSTGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNCLQRDNLTQFFPQNYFPLLGQEVVQALKAVVNFLQDGLDCSVSFVSRVLGKVCIQGRKREILSVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVVTRKLLLLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEALTTSEDMERWEASLKGLEGLVYRSPTATREVSVELAKVLLHLEEKTCVAEFEQLRQSALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPKSLQRRSQHGPPVPGTMCSPALAVSQTGNVAAPDWQVVVEERIRSKTRRFSKGCPQRELSGVPNEFSSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAVRALLLLERLKDKLLSSSSPQP

Target ORF information:

RefSeq Version	NM_027880.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027880.2

ORF Insert Sequence:

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGCTTTGA CTACATCTGA GGACATGGAA CGCTGGGAGG CGTCCCTAAA GGGGCTTGAG 
GGCCTGGTAT ATAGGAGCCC CACGGCCACT CGGGAGGTGA GTGTGGAGCT GGCCAAAGTG 
CTACTGCACC TGGAAGAGAA GACCTGTGTA GCAGAGTTTG AGCAGCTGCG CCAGAGCGCT 
CTGGTAGCTG TTACAGTCAC AGACCCGGAG CAGGTAGCCA AGTATCTGAC CTCACAGTTC 
TATGGCCTAA ACTATAGCCT CCGCCAGCGC ATGGACATCC TGGACGTCCT TGTTCTGGCT 
GCCCAGGCAC TGTCTCGGCC AAAGAGCCTG CAGAGACGTT CCCAGCACGG TCCCCCCGTT 
CCTGGCACCA TGTGTTCACC AGCACTAGCC GTTTCTCAGA CTGGCAATGT CGCTGCTCCT 
GACTGGCAGG TGGTTGTGGA GGAGCGGATC AGAAGCAAGA CCCGGAGGTT CTCGAAGGGC 
TGTCCTCAGC GGGAGCTGTC AGGCGTCCCC AATGAATTCA GCTCTGTGGC TGGCTACTTC 
TTCTTCCCCC TCCTTCAGCA CTTTGACAGG CCTCTGGTGA CCTTCGACCT TTTAGGAGAT 
GATCAGTTGG TACTTGGAAG ACTGACCCAC ACCTTAGCGT CCCTGATGTA CCTGGCTGTT 
AACACCACAG TGGCTGTGCC TATGGGTAAG GCCCTGCTGG AGTTTGTATG GGCCCTTCGC 
TTCCACGTTG ACATTTACGT GCGCCGGGGC TTGCTGTCTG CTGTGTCCTC TGTCCTCCTC 
AGTGTACCCA CAGAGCGGCT GCTGGGGGAC CTGCCAGATG AGCTACTGGA AGCCAGATCC 
TGGTTGGCAG ATGTGGCTGA GAAGGATGTG GACGAGGACT GTAGGGAGCT GGCAGTAAGG 
GCTCTGCTGC TTCTGGAGAG ACTCAAAGAC AAGCTCCTGT CCAGTTCCTC TCCACAGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Telo2 ( NM_001163661.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157133.1 Mus musculus telomere maintenance 2 (Telo2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04714
Clone ID Related Accession (Same CDS sequence)	NM_027880.2 , NM_001163661.1
Accession Version	NM_001163661.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143827.1, AK146963.1 and BB083455.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK143827.1, AK154727.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGCTTTGA CTACATCTGA GGACATGGAA CGCTGGGAGG CGTCCCTAAA GGGGCTTGAG 
GGCCTGGTAT ATAGGAGCCC CACGGCCACT CGGGAGGTGA GTGTGGAGCT GGCCAAAGTG 
CTACTGCACC TGGAAGAGAA GACCTGTGTA GCAGAGTTTG AGCAGCTGCG CCAGAGCGCT 
CTGGTAGCTG TTACAGTCAC AGACCCGGAG CAGGTAGCCA AGTATCTGAC CTCACAGTTC 
TATGGCCTAA ACTATAGCCT CCGCCAGCGC ATGGACATCC TGGACGTCCT TGTTCTGGCT 
GCCCAGGCAC TGTCTCGGCC AAAGAGCCTG CAGAGACGTT CCCAGCACGG TCCCCCCGTT 
CCTGGCACCA TGTGTTCACC AGCACTAGCC GTTTCTCAGA CTGGCAATGT CGCTGCTCCT 
GACTGGCAGG TGGTTGTGGA GGAGCGGATC AGAAGCAAGA CCCGGAGGTT CTCGAAGGGC 
TGTCCTCAGC GGGAGCTGTC AGGCGTCCCC AATGAATTCA GCTCTGTGGC TGGCTACTTC 
TTCTTCCCCC TCCTTCAGCA CTTTGACAGG CCTCTGGTGA CCTTCGACCT TTTAGGAGAT 
GATCAGTTGG TACTTGGAAG ACTGACCCAC ACCTTAGCGT CCCTGATGTA CCTGGCTGTT 
AACACCACAG TGGCTGTGCC TATGGGTAAG GCCCTGCTGG AGTTTGTATG GGCCCTTCGC 
TTCCACGTTG ACATTTACGT GCGCCGGGGC TTGCTGTCTG CTGTGTCCTC TGTCCTCCTC 
AGTGTACCCA CAGAGCGGCT GCTGGGGGAC CTGCCAGATG AGCTACTGGA AGCCAGATCC 
TGGTTGGCAG ATGTGGCTGA GAAGGATGTG GACGAGGACT GTAGGGAGCT GGCAGTAAGG 
GCTCTGCTGC TTCTGGAGAG ACTCAAAGAC AAGCTCCTGT CCAGTTCCTC TCCACAGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157133.1
CDS	570..3092
Translation	MDPALSAVRLTVQEAIHILSSSEDAGHILSTLGTLKRYLGGTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPGGQLERLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMAQLLDTFLSTGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNCLQRDNLTQFFPQNYFPLLGQEVVQALKAVVNFLQDGLDCSVSFVSRVLGKVCIQGRKREILSVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVVTRKLLLLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEALTTSEDMERWEASLKGLEGLVYRSPTATREVSVELAKVLLHLEEKTCVAEFEQLRQSALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPKSLQRRSQHGPPVPGTMCSPALAVSQTGNVAAPDWQVVVEERIRSKTRRFSKGCPQRELSGVPNEFSSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAVRALLLLERLKDKLLSSSSPQP

Target ORF information:

RefSeq Version	NM_001163661.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163661.1

ORF Insert Sequence:

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGCTTTGA CTACATCTGA GGACATGGAA CGCTGGGAGG CGTCCCTAAA GGGGCTTGAG 
GGCCTGGTAT ATAGGAGCCC CACGGCCACT CGGGAGGTGA GTGTGGAGCT GGCCAAAGTG 
CTACTGCACC TGGAAGAGAA GACCTGTGTA GCAGAGTTTG AGCAGCTGCG CCAGAGCGCT 
CTGGTAGCTG TTACAGTCAC AGACCCGGAG CAGGTAGCCA AGTATCTGAC CTCACAGTTC 
TATGGCCTAA ACTATAGCCT CCGCCAGCGC ATGGACATCC TGGACGTCCT TGTTCTGGCT 
GCCCAGGCAC TGTCTCGGCC AAAGAGCCTG CAGAGACGTT CCCAGCACGG TCCCCCCGTT 
CCTGGCACCA TGTGTTCACC AGCACTAGCC GTTTCTCAGA CTGGCAATGT CGCTGCTCCT 
GACTGGCAGG TGGTTGTGGA GGAGCGGATC AGAAGCAAGA CCCGGAGGTT CTCGAAGGGC 
TGTCCTCAGC GGGAGCTGTC AGGCGTCCCC AATGAATTCA GCTCTGTGGC TGGCTACTTC 
TTCTTCCCCC TCCTTCAGCA CTTTGACAGG CCTCTGGTGA CCTTCGACCT TTTAGGAGAT 
GATCAGTTGG TACTTGGAAG ACTGACCCAC ACCTTAGCGT CCCTGATGTA CCTGGCTGTT 
AACACCACAG TGGCTGTGCC TATGGGTAAG GCCCTGCTGG AGTTTGTATG GGCCCTTCGC 
TTCCACGTTG ACATTTACGT GCGCCGGGGC TTGCTGTCTG CTGTGTCCTC TGTCCTCCTC 
AGTGTACCCA CAGAGCGGCT GCTGGGGGAC CTGCCAGATG AGCTACTGGA AGCCAGATCC 
TGGTTGGCAG ATGTGGCTGA GAAGGATGTG GACGAGGACT GTAGGGAGCT GGCAGTAAGG 
GCTCTGCTGC TTCTGGAGAG ACTCAAAGAC AAGCTCCTGT CCAGTTCCTC TCCACAGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Telo2 ( XM_011246619.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244921.1 Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.

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CloneID	OMu70733
Clone ID Related Accession (Same CDS sequence)	XM_011246619.2 , XM_011246619.3
Accession Version	XM_011246619.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	telomere length regulation protein TEL2 homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246619.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGGTGGGC TTCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244921.1
CDS	577..2154
Translation	MDPALSAVRLTVQEAIHILSSSEDAGHILSTLGTLKRYLGGTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPGGQLERLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMAQLLDTFLSTGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNCLQRDNLTQFFPQNYFPLLGQEVVQALKAVVNFLQDGLDCSVSFVSRVLGKVCIQGRKREILSVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVVTRKLLLLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEGGLR

Target ORF information:

RefSeq Version	XM_011246619.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus telomere maintenance 2 (Telo2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246619.3

ORF Insert Sequence:

ATGGACCCAG CCCTGTCTGC TGTCCGGCTC ACCGTCCAGG AAGCCATTCA CATCCTTTCA 
TCCTCAGAGG ATGCTGGCCA TATCCTTTCT ACCCTGGGGA CTCTGAAACG ATACCTCGGT 
GGAACCGAGG ATCCAGTTCT TCCTGAGGAG AAGGAGGAGT TTGCCACTGT CCACTTCTCA 
GCCGTCCTTA GATGTCTGGT CAGCAAGCTG AGCCCAGGTT GGCTGGAGCT GTCCCCCGGT 
GGCCAGCTGG AGCGGCTTTG GGAGAGCTTC TTCCTGGATG GCCCTCCAGA CCAAGCCTTC 
CTGGTGCTGA TGGAAGCCAT TGAGAGCACT GCTGGCCCTA GCTTCCGTCT GATGAAGATG 
GCTCAGCTGC TGGACACATT TCTGAGCACG GGCAGAGTGG CTGCTCTAAT GGAGGAGCAG 
TGTCGGCCAC AGACAAAGCC CAGCTTTCCC CTGTTCCAGG AGACGCTGCT CAGCAAGGTT 
GTGGGCTTAC CTGATCTCCT GGGCAACTGT CTCCAGCGGG ACAACCTGAC CCAGTTCTTC 
CCCCAGAACT ACTTCCCTCT GCTTGGCCAG GAGGTTGTGC AGGCACTAAA GGCAGTTGTG 
AACTTTCTCC AAGATGGCCT AGACTGCTCT GTCTCCTTCG TATCTCGAGT TCTTGGGAAG 
GTCTGCATCC AGGGCCGAAA GAGAGAGATC CTGAGTGTGC TGGTGCCCCA GCTGACAGTG 
CTCACCCAGG ACAGCTGTCT GTGGCAGCGG GTGTGCTGGC GCCTGGTGGA GCAGGTGCCT 
GACCGGGCAG TGGAGGCTGT GCTGACAGGA CTTGTAGAGG CTGCTCCCAG GCCTGAAGTC 
CTGTCACGAC TACTAGGGAA CCTGGTGGTG AAGAATAAGA AAGCGCGGTT TGTGGTTACC 
CGCAAGCTCC TGCTCCTGCA GTACCAGCAC ACGACACCCA TGGTGCAGAG CCTGTTGGGG 
TACTTGGCTC TAGACAGTCA GCGGCGGCCA CTCCTCATAC AGGTGCTTAA GGAGCTGCTG 
GAGACCTGGG GCTGCAGCAG TGCTGTCCGA CACACACCCC TGGAGCAGCA GTGTTACATC 
AGCAAGGCCA TCCTTGTCTG CCTGGCACAC CTCGGGGAGC CGGAGCTGCA GGACATCCGG 
GATGAATTGC TGGCCAGCAT GATGGCAGGC GTGAAGTGCC GCCTGGATAG CAGCCTGCCC 
CCTGTGCGCC GCTTGGGCAT GATTGTGGCC GAGGTCATCA GCTCCAGGAT CCACCCTGAG 
GGGCCTCTCC TGAAATTCCA ATATGAAGAT GACGAGATGA GCCGTGAGTT GCTGGCTTTG 
GCTACCCCGG AGCCTGCGGG TGACTGCTCC TCGGTGTCAC GAGGCCCATC CCCAGCTCCT 
GTTGACACAG AGTCTCCTGT AGAGATGCCA GAAAAGGCCG TGGAGAGTGA TGTCCCCCCA 
ACTCAGCCTC AGGGCTCTGA CTCGGAGCTG GACAGTGACG ATGAGTTCAT CCCCTATGAC 
ATGTCAGGGG ACAGAGAGCT GAAGAGCAGC AAGGAGCCCC TGTATATCCG AGACTGCGTG 
GAAGGTGGGC TTCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1.
Structure (London, England : 1993)22(6)805-18(2014 Jun)
Pal M,Morgan M,Phelps SE,Roe SM,Parry-Morris S,Downs JA,Polier S,Pearl LH,Prodromou C

Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
Molecular cell54(1)119-132(2014 Apr)
Rao F,Cha J,Xu J,Xu R,Vandiver MS,Tyagi R,Tokhunts R,Koldobskiy MA,Fu C,Barrow R,Wu M,Fiedler D,Barrow JC,Snyder SH

CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.
Molecular cell39(6)839-50(2010 Sep)
Horejs? Z,Takai H,Adelman CA,Collis SJ,Flynn H,Maslen S,Skehel JM,de Lange T,Boulton SJ

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Genes & development24(18)2019-30(2010 Sep)
Takai H,Xie Y,de Lange T,Pavletich NP

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Telo2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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