Gpr15 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gpr15
Entrez Gene ID	71223
Full Name	G protein-coupled receptor 15
Synonyms	4933439K08Rik
General protein information	Preferred Names G protein-coupled receptor 15 Names G-protein coupled receptor 15
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 C1.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001162955.1	NP_001156427.1	G-protein coupled receptor 15
NM_001162955.2	NP_001156427.1	G-protein coupled receptor 15

Pathways from BioSystems

Homologies

Homo sapiens (human)	GPR15	NP_005281.1
Pan troglodytes (chimpanzee)	GPR15	NP_001009030.1
Rattus norvegicus (Norway rat)	Gpr15	NP_001099360.1
	GPR15	NP_001036112.1
Bos taurus (cattle)	GPR15	XP_005201274.1
Gallus gallus (chicken)	GPR15	XP_004938269.1
Mus musculus (house mouse)	Gpr15	NP_001156427.1
Canis lupus familiaris (dog)	GPR15	XP_005639430.1

Gene Ontology
Bibliography

Related articles in PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Suply T, Hannedouche S, Carte N, Li J, Grosshans B, Schaefer M, Raad L, Beck V, Vidal S, Hiou-Feige A, Beluch N, Barbieri S, Wirsching J, Lageyre N, Hillger F, Debon C, Dawson J, Smith P, Lannoy V, Detheux M, Bitsch F, Falchetto R, Bouwmeester T, Porter J, Baumgarten B, Mansfield K, Carballido JM, Seuwen K, Bassilana F
Science signaling10(496)(2017 Sep)

G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin.
Pan B, Wang X, Nishioka C, Honda G, Yokoyama A, Zeng L, Xu K, Ikezoe T
Scientific reports7(1)692(2017 Apr)

The fifth epidermal growth factor like region of thrombomodulin alleviates LPS-induced sepsis through interacting with GPR15.
Pan B, Wang X, Kojima S, Nishioka C, Yokoyama A, Honda G, Xu K, Ikezoe T
Thrombosis and haemostasis117(3)570-579(2017 Feb)

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Oc?n B, Pan J, Dinh TT, Chen W, Ballet R, Bscheider M, Habtezion A, Tu H, Zabel BA, Butcher EC
Frontiers in immunology81111(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings establish a role for GPR15 in skin lymphocyte homing and suggest that it may contribute to lymphocyte subset targeting to diverse epithelial sites.
Title: Orphan chemoattractant receptor GPR15 mediates dendritic epidermal T-cell recruitment to the skin.

findings describe a T cell-homing receptor for large intestine lamina propria and indicate that GPR15 plays a role in mucosal immune tolerance largely by regulating the influx of Tregs
Title: GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.

The following Gpr15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gpr15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu58518	NM_001162955.2 Latest version!	Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OMu58518	NM_001162955.1	Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gpr15 ( NM_001162955.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001156427.1 Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.

Price & Availability↑

CloneID	OMu58518
Clone ID Related Accession (Same CDS sequence)	NM_001162955.1 , NM_001162955.2
Accession Version	NM_001162955.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Mus musculus(house mouse)
Product	G-protein coupled receptor 15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC159200.2. On or before Jul 2, 2009 this sequence version replaced XM_916786.3, XM_156321.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: BC119501.1, BC107281.2 [ECO:0000345] ##Evidence-Data-END##

ATGGAACCAG CAACAGCCCT GCTGATTGTG GATTACTATG ACTACACAAG CCCAGATCCT 
CCTTTCCTGG AGACTCCCTC CCACCTGTCC TACACATCTG TCTTCCTCCC TATCTTTTAC 
ACAGTTGTAT TCTTGACTGG AGTGGTGGGG AATTTCATCC TCATGATAGC TCTGCATTTC 
AAACGCGGCA ACCGAAGATT GATCGACATC TTTATCATCA ACCTGGCTGC CTCTGACTTC 
ATTTTCCTTG TCACAGTGCC TCTTTGGATG GATAAGGAAG CCTCTCTAGG ACTATGGAGG 
ACTGGCTCTT TCCTGTGCAA AGGCAGCTCC TATGTGATCT CCGTGAACAT GCACTGTAGT 
GTCTTCTTGC TCACATGCAT GAGCATGGAC CGTTACCTGG CTATCATGCA CCCAGCCTTA 
GCCAAGAGAT TACGAAGGAG AAGCTCTGCA TATGCAGTGT GTGCCGTCGT CTGGATCATC 
TCATGCGTCC TGGGGTTGCC CACTCTTCTG TCCAGGGAGC TCACTCACAT TGAAGGCAAA 
CCATACTGTG CAGAGAAGAA ACCCACGTCC TTAAAACTGA TGTGGGGCCT GGTAGCCTTG 
ATTACCACCT TTTTCGTCCC CCTCCTGAGC ATTGTGACCT GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAACTAAA GAAGTCCATA 
AAGATCGTTA TTATTGCGGT GGCGGCCTTC ACCGTCTCCT GGGTACCCTT TAACACTTTC 
AAGCTCCTAG CCATTGTTTC AGGGTTCCAG CCAGAAGGCC TTTTTCACTC CGAGGCTTTG 
CAGCTGGCCA TGAATGTGAC TGGGCCCTTG GCCTTTGCCA GCAGCTGTGT CAACCCTCTC 
ATTTACTATG TCTTTGACAG CTATATCCGC CGGGCCATTG TACGTTGTCT GTGCCCTTGT 
CTGAAGACCC ACAACTTTGG GAGCAGCACT GAGACATCGG ACAGTCACCT CACTAAGGCT 
CTTTCCAACT TCATTCATGC AGAGGATTTC ATCCGGCGGA GGAAGAGATC TGTGTCACTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156427.1
CDS	1..1083
Translation	MEPATALLIVDYYDYTSPDPPFLETPSHLSYTSVFLPIFYTVVFLTGVVGNFILMIALHFKRGNRRLIDIFIINLAASDFIFLVTVPLWMDKEASLGLWRTGSFLCKGSSYVISVNMHCSVFLLTCMSMDRYLAIMHPALAKRLRRRSSAYAVCAVVWIISCVLGLPTLLSRELTHIEGKPYCAEKKPTSLKLMWGLVALITTFFVPLLSIVTCYCCITRRLCAHYQQSGKHNKKLKKSIKIVIIAVAAFTVSWVPFNTFKLLAIVSGFQPEGLFHSEALQLAMNVTGPLAFASSCVNPLIYYVFDSYIRRAIVRCLCPCLKTHNFGSSTETSDSHLTKALSNFIHAEDFIRRRKRSVSL

Target ORF information:

RefSeq Version	NM_001162955.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001162955.1

ORF Insert Sequence:

ATGGAACCAG CAACAGCCCT GCTGATTGTG GATTACTATG ACTACACAAG CCCAGATCCT 
CCTTTCCTGG AGACTCCCTC CCACCTGTCC TACACATCTG TCTTCCTCCC TATCTTTTAC 
ACAGTTGTAT TCTTGACTGG AGTGGTGGGG AATTTCATCC TCATGATAGC TCTGCATTTC 
AAACGCGGCA ACCGAAGATT GATCGACATC TTTATCATCA ACCTGGCTGC CTCTGACTTC 
ATTTTCCTTG TCACAGTGCC TCTTTGGATG GATAAGGAAG CCTCTCTAGG ACTATGGAGG 
ACTGGCTCTT TCCTGTGCAA AGGCAGCTCC TATGTGATCT CCGTGAACAT GCACTGTAGT 
GTCTTCTTGC TCACATGCAT GAGCATGGAC CGTTACCTGG CTATCATGCA CCCAGCCTTA 
GCCAAGAGAT TACGAAGGAG AAGCTCTGCA TATGCAGTGT GTGCCGTCGT CTGGATCATC 
TCATGCGTCC TGGGGTTGCC CACTCTTCTG TCCAGGGAGC TCACTCACAT TGAAGGCAAA 
CCATACTGTG CAGAGAAGAA ACCCACGTCC TTAAAACTGA TGTGGGGCCT GGTAGCCTTG 
ATTACCACCT TTTTCGTCCC CCTCCTGAGC ATTGTGACCT GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAACTAAA GAAGTCCATA 
AAGATCGTTA TTATTGCGGT GGCGGCCTTC ACCGTCTCCT GGGTACCCTT TAACACTTTC 
AAGCTCCTAG CCATTGTTTC AGGGTTCCAG CCAGAAGGCC TTTTTCACTC CGAGGCTTTG 
CAGCTGGCCA TGAATGTGAC TGGGCCCTTG GCCTTTGCCA GCAGCTGTGT CAACCCTCTC 
ATTTACTATG TCTTTGACAG CTATATCCGC CGGGCCATTG TACGTTGTCT GTGCCCTTGT 
CTGAAGACCC ACAACTTTGG GAGCAGCACT GAGACATCGG ACAGTCACCT CACTAAGGCT 
CTTTCCAACT TCATTCATGC AGAGGATTTC ATCCGGCGGA GGAAGAGATC TGTGTCACTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gpr15 ( NM_001162955.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001156427.1 Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.

Price & Availability↑

CloneID	OMu58518
Clone ID Related Accession (Same CDS sequence)	NM_001162955.1 , NM_001162955.2
Accession Version	NM_001162955.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	G-protein coupled receptor 15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC159200.2. On Jun 19, 2019 this sequence version replaced NM_001162955.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: BC107281.2 [ECO:0000345] ##Evidence-Data-END##

ATGGAACCAG CAACAGCCCT GCTGATTGTG GATTACTATG ACTACACAAG CCCAGATCCT 
CCTTTCCTGG AGACTCCCTC CCACCTGTCC TACACATCTG TCTTCCTCCC TATCTTTTAC 
ACAGTTGTAT TCTTGACTGG AGTGGTGGGG AATTTCATCC TCATGATAGC TCTGCATTTC 
AAACGCGGCA ACCGAAGATT GATCGACATC TTTATCATCA ACCTGGCTGC CTCTGACTTC 
ATTTTCCTTG TCACAGTGCC TCTTTGGATG GATAAGGAAG CCTCTCTAGG ACTATGGAGG 
ACTGGCTCTT TCCTGTGCAA AGGCAGCTCC TATGTGATCT CCGTGAACAT GCACTGTAGT 
GTCTTCTTGC TCACATGCAT GAGCATGGAC CGTTACCTGG CTATCATGCA CCCAGCCTTA 
GCCAAGAGAT TACGAAGGAG AAGCTCTGCA TATGCAGTGT GTGCCGTCGT CTGGATCATC 
TCATGCGTCC TGGGGTTGCC CACTCTTCTG TCCAGGGAGC TCACTCACAT TGAAGGCAAA 
CCATACTGTG CAGAGAAGAA ACCCACGTCC TTAAAACTGA TGTGGGGCCT GGTAGCCTTG 
ATTACCACCT TTTTCGTCCC CCTCCTGAGC ATTGTGACCT GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAACTAAA GAAGTCCATA 
AAGATCGTTA TTATTGCGGT GGCGGCCTTC ACCGTCTCCT GGGTACCCTT TAACACTTTC 
AAGCTCCTAG CCATTGTTTC AGGGTTCCAG CCAGAAGGCC TTTTTCACTC CGAGGCTTTG 
CAGCTGGCCA TGAATGTGAC TGGGCCCTTG GCCTTTGCCA GCAGCTGTGT CAACCCTCTC 
ATTTACTATG TCTTTGACAG CTATATCCGC CGGGCCATTG TACGTTGTCT GTGCCCTTGT 
CTGAAGACCC ACAACTTTGG GAGCAGCACT GAGACATCGG ACAGTCACCT CACTAAGGCT 
CTTTCCAACT TCATTCATGC AGAGGATTTC ATCCGGCGGA GGAAGAGATC TGTGTCACTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001156427.1
CDS	149..1231
Translation	MEPATALLIVDYYDYTSPDPPFLETPSHLSYTSVFLPIFYTVVFLTGVVGNFILMIALHFKRGNRRLIDIFIINLAASDFIFLVTVPLWMDKEASLGLWRTGSFLCKGSSYVISVNMHCSVFLLTCMSMDRYLAIMHPALAKRLRRRSSAYAVCAVVWIISCVLGLPTLLSRELTHIEGKPYCAEKKPTSLKLMWGLVALITTFFVPLLSIVTCYCCITRRLCAHYQQSGKHNKKLKKSIKIVIIAVAAFTVSWVPFNTFKLLAIVSGFQPEGLFHSEALQLAMNVTGPLAFASSCVNPLIYYVFDSYIRRAIVRCLCPCLKTHNFGSSTETSDSHLTKALSNFIHAEDFIRRRKRSVSL

Target ORF information:

RefSeq Version	NM_001162955.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor 15 (Gpr15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001162955.2

ORF Insert Sequence:

ATGGAACCAG CAACAGCCCT GCTGATTGTG GATTACTATG ACTACACAAG CCCAGATCCT 
CCTTTCCTGG AGACTCCCTC CCACCTGTCC TACACATCTG TCTTCCTCCC TATCTTTTAC 
ACAGTTGTAT TCTTGACTGG AGTGGTGGGG AATTTCATCC TCATGATAGC TCTGCATTTC 
AAACGCGGCA ACCGAAGATT GATCGACATC TTTATCATCA ACCTGGCTGC CTCTGACTTC 
ATTTTCCTTG TCACAGTGCC TCTTTGGATG GATAAGGAAG CCTCTCTAGG ACTATGGAGG 
ACTGGCTCTT TCCTGTGCAA AGGCAGCTCC TATGTGATCT CCGTGAACAT GCACTGTAGT 
GTCTTCTTGC TCACATGCAT GAGCATGGAC CGTTACCTGG CTATCATGCA CCCAGCCTTA 
GCCAAGAGAT TACGAAGGAG AAGCTCTGCA TATGCAGTGT GTGCCGTCGT CTGGATCATC 
TCATGCGTCC TGGGGTTGCC CACTCTTCTG TCCAGGGAGC TCACTCACAT TGAAGGCAAA 
CCATACTGTG CAGAGAAGAA ACCCACGTCC TTAAAACTGA TGTGGGGCCT GGTAGCCTTG 
ATTACCACCT TTTTCGTCCC CCTCCTGAGC ATTGTGACCT GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAACTAAA GAAGTCCATA 
AAGATCGTTA TTATTGCGGT GGCGGCCTTC ACCGTCTCCT GGGTACCCTT TAACACTTTC 
AAGCTCCTAG CCATTGTTTC AGGGTTCCAG CCAGAAGGCC TTTTTCACTC CGAGGCTTTG 
CAGCTGGCCA TGAATGTGAC TGGGCCCTTG GCCTTTGCCA GCAGCTGTGT CAACCCTCTC 
ATTTACTATG TCTTTGACAG CTATATCCGC CGGGCCATTG TACGTTGTCT GTGCCCTTGT 
CTGAAGACCC ACAACTTTGG GAGCAGCACT GAGACATCGG ACAGTCACCT CACTAAGGCT 
CTTTCCAACT TCATTCATGC AGAGGATTTC ATCCGGCGGA GGAAGAGATC TGTGTCACTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Science signaling10(496)(2017 Sep)
Suply T,Hannedouche S,Carte N,Li J,Grosshans B,Schaefer M,Raad L,Beck V,Vidal S,Hiou-Feige A,Beluch N,Barbieri S,Wirsching J,Lageyre N,Hillger F,Debon C,Dawson J,Smith P,Lannoy V,Detheux M,Bitsch F,Falchetto R,Bouwmeester T,Porter J,Baumgarten B,Mansfield K,Carballido JM,Seuwen K,Bassilana F

G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin.
Scientific reports7(1)692(2017 Apr)
Pan B,Wang X,Nishioka C,Honda G,Yokoyama A,Zeng L,Xu K,Ikezoe T

The fifth epidermal growth factor like region of thrombomodulin alleviates LPS-induced sepsis through interacting with GPR15.
Thrombosis and haemostasis117(3)570-579(2017 Feb)
Pan B,Wang X,Kojima S,Nishioka C,Yokoyama A,Honda G,Xu K,Ikezoe T

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Frontiers in immunology81111(2017)
Oc?n B,Pan J,Dinh TT,Chen W,Ballet R,Bscheider M,Habtezion A,Tu H,Zabel BA,Butcher EC

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Gpr15 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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