Dcxr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dcxr
Entrez Gene ID	67880
Full Name	dicarbonyl L-xylulose reductase
Synonyms	0610038K04Rik,1810027P18Rik,XR
General protein information	Preferred Names dicarbonyl L-xylulose reductase Names L-xylulose reductase diacetyl/L-xylulose reductase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_026428.3	NP_080704.2	L-xylulose reductase isoform 1
XM_006534027.3	XP_006534090.1	L-xylulose reductase isoform X1
NM_026428.2	NP_080704.2	L-xylulose reductase isoform 1
NM_001347608.1	NP_001334537.1	L-xylulose reductase isoform 2

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008502	XP_316941.3
Caenorhabditis elegans (roundworm)	dhs-21	NP_506182.2
Pan troglodytes (chimpanzee)	DCXR	XP_001167023.2
	DCXR	XP_001112983.1
Canis lupus familiaris (dog)	DCXR	XP_005624203.1
Mus musculus (house mouse)	Dcxr	NP_080704.2
Gallus gallus (chicken)	DCXR	NP_989556.1
Xenopus tropicalis (tropical clawed frog)	dcxr	NP_989100.1
Rattus norvegicus (Norway rat)	Dcxr	NP_599214.1
Homo sapiens (human)	DCXR	NP_057370.1
Bos taurus (cattle)	DCXR	NP_001069359.1
Danio rerio (zebrafish)	dcxr	NP_001017619.1
Drosophila melanogaster (fruit fly)	CG7322	NP_001259693.1

Gene Ontology
Bibliography

Related articles in PubMed

Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
Hubbs AF, Fluharty KL, Edwards RJ, Barnabei JL, Grantham JT, Palmer SM, Kelly F, Sargent LM, Reynolds SH, Mercer RR, Goravanahally MP, Kashon ML, Honaker JC, Jackson MC, Cumpston AM, Goldsmith WT, McKinney W, Fedan JS, Battelli LA, Munro T, Bucklew-Moyers W, McKinstry K, Schwegler-Berry D, Friend S, Knepp AK, Smith SL, Sriram K
The American journal of pathology186(11)2887-2908(2016 Nov)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Abdallah BM, Ditzel N, Mahmood A, Isa A, Traustadottir GA, Schilling AF, Ruiz-Hidalgo MJ, Laborda J, Amling M, Kassem M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research26(7)1457-71(2011 Jul)

Transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-Ay diabetic model mice: an animal model for the metabolism of renal carbonyl compounds.
Sudo T, Ishii A, Asami J, Uematsu Y, Saitoh M, Nakamura A, Tada N, Ohnuki T, Komurasaki T, Nakagawa J
Experimental animals54(5)385-94(2005 Oct)

Quantitative trait loci for steady-state platelet count in mice.
Cheung CC, Martin IC, Zenger KR, Donald JA, Thomson PC, Moran C, Buckley MF
Mammalian genome : official journal of the International Mammalian Genome Society15(10)784-97(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DCXR might function in the metabolism of glucose or carbonyl compounds, and play a protective role in a kidney which is under hyperglycemic pressure.
Title: Transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-Ay diabetic model mice: an animal model for the metabolism of renal carbonyl compounds.

highly expressed in kidney and liver
Title: Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.

The following Dcxr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dcxr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02262	NM_026428.3 Latest version!	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu46810	NM_001347608.1 Latest version!	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu46808	XM_006534027.3 Latest version!	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OMu02262	NM_026428.2	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dcxr ( NM_026428.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080704.2 Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02262
Clone ID Related Accession (Same CDS sequence)	NM_026428.3 , NM_026428.2
Accession Version	NM_026428.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	L-xylulose reductase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL663030.12, AK007627.1, AK153521.1 and BY500715.1. On May 3, 2018 this sequence version replaced NM_026428.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BI219348.1, AK004023.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGT TCCACCAAGG GTGCTCTGGA CATGTTGACC 
AAGATGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGACCAAC TGGAGTGACC CCCACAAAGC TAAGGCCATG 
CTGGATCGTA TCCCACTGGG CAAGTTCGCT GAGGTGGAGA ACGTCGTGGA CACCATTCTC 
TTCCTGCTGA GCAACCGGAG TGGCATGACC ACTGGCTCCA CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080704.2
CDS	56..790
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT

Target ORF information:

RefSeq Version	NM_026428.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026428.3

ORF Insert Sequence:

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGT TCCACCAAGG GTGCTCTGGA CATGTTGACC 
AAGATGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGACCAAC TGGAGTGACC CCCACAAAGC TAAGGCCATG 
CTGGATCGTA TCCCACTGGG CAAGTTCGCT GAGGTGGAGA ACGTCGTGGA CACCATTCTC 
TTCCTGCTGA GCAACCGGAG TGGCATGACC ACTGGCTCCA CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dcxr ( NM_026428.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080704.2 Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02262
Clone ID Related Accession (Same CDS sequence)	NM_026428.3 , NM_026428.2
Accession Version	NM_026428.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-29
Organism	Mus musculus(house mouse)
Product	L-xylulose reductase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK007627.1, AK153521.1 and BY500715.1. On Apr 28, 2007 this sequence version replaced NM_026428.1. ##Evidence-Data-START## Transcript exon combination :: AK004023.1, BY704272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGT TCCACCAAGG GTGCTCTGGA CATGTTGACC 
AAGATGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGACCAAC TGGAGTGACC CCCACAAAGC TAAGGCCATG 
CTGGATCGTA TCCCACTGGG CAAGTTCGCT GAGGTGGAGA ACGTCGTGGA CACCATTCTC 
TTCCTGCTGA GCAACCGGAG TGGCATGACC ACTGGCTCCA CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080704.2
CDS	53..787
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT

Target ORF information:

RefSeq Version	NM_026428.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026428.2

ORF Insert Sequence:

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGT TCCACCAAGG GTGCTCTGGA CATGTTGACC 
AAGATGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGACCAAC TGGAGTGACC CCCACAAAGC TAAGGCCATG 
CTGGATCGTA TCCCACTGGG CAAGTTCGCT GAGGTGGAGA ACGTCGTGGA CACCATTCTC 
TTCCTGCTGA GCAACCGGAG TGGCATGACC ACTGGCTCCA CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dcxr ( NM_001347608.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334537.1 Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu46810
Clone ID Related Accession (Same CDS sequence)	NM_001347608.1
Accession Version	NM_001347608.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	L-xylulose reductase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL663030.12. On Dec 2, 2016 this sequence version replaced XM_006534029.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BI102923.1, BG968527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGG TGCCCTCCCA TGTTGTTTAC CTTGCTGGCA 
TCTCTTCAGA TCCGTGTGAA TGCAGTAAAC CCCACAGTAG TGATGACACC CATGGGCCGG 
ACCAACTGGA GTGACCCCCA CAAAGCTAAG GCCATGCTGG ATCGTATCCC ACTGGGCAAG 
TTCGCTGAGG TGGAGAACGT CGTGGACACC ATTCTCTTCC TGCTGAGCAA CCGGAGTGGC 
ATGACCACTG GCTCCACTTT GCCAGTGGAT GGGGGCTTCC TGGCTACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334537.1
CDS	56..766
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYWCPPMLFTLLASLQIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT

Target ORF information:

RefSeq Version	NM_001347608.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347608.1

ORF Insert Sequence:

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGAT TGTGGCCAAG 
GGCATGATAG CTCGGGGAGT TCCAGGAGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAA 
CGTGCACTGA CCAACCATAC TGTCTACTGG TGCCCTCCCA TGTTGTTTAC CTTGCTGGCA 
TCTCTTCAGA TCCGTGTGAA TGCAGTAAAC CCCACAGTAG TGATGACACC CATGGGCCGG 
ACCAACTGGA GTGACCCCCA CAAAGCTAAG GCCATGCTGG ATCGTATCCC ACTGGGCAAG 
TTCGCTGAGG TGGAGAACGT CGTGGACACC ATTCTCTTCC TGCTGAGCAA CCGGAGTGGC 
ATGACCACTG GCTCCACTTT GCCAGTGGAT GGGGGCTTCC TGGCTACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dcxr ( XM_006534027.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006534090.1 Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu46808
Clone ID Related Accession (Same CDS sequence)	XM_006534027.3
Accession Version	XM_006534027.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	L-xylulose reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006534027.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGGT GAGCTGCCCT 
ACCCGGCTGG CTGGCGCAGG AACTCAGAAG AAGAGAGTTA GTTCTGCTTC ATGTCCCTCA 
AAATTTCAGA TTGTGGCCAA GGGCATGATA GCTCGGGGAG TTCCAGGAGC CATTGTGAAT 
GTCTCCAGCC AGGCCTCCCA ACGTGCACTG ACCAACCATA CTGTCTACTG TTCCACCAAG 
GGTGCTCTGG ACATGTTGAC CAAGATGATG GCCCTAGAGC TTGGGCCCCA CAAGATCCGT 
GTGAATGCAG TAAACCCCAC AGTAGTGATG ACACCCATGG GCCGGACCAA CTGGAGTGAC 
CCCCACAAAG CTAAGGCCAT GCTGGATCGT ATCCCACTGG GCAAGTTCGC TGAGGTGGAG 
AACGTCGTGG ACACCATTCT CTTCCTGCTG AGCAACCGGA GTGGCATGAC CACTGGCTCC 
ACTTTGCCAG TGGATGGGGG CTTCCTGGCT ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006534090.1
CDS	95..910
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQVSCPTRLAGAGTQKKRVSSASCPSKFQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNPTVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDGGFLAT

Target ORF information:

RefSeq Version	XM_006534027.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dicarbonyl L-xylulose reductase (Dcxr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006534027.3

ORF Insert Sequence:

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCGTT GAAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACGACCT GGTCCGCGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAGCAGGCC CTAAGCAATG TGGGACCCGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TCTGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACATCCT TCAATGTGAA TCTTCGGGCT GTCATCCAGG TGTCTCAGGT GAGCTGCCCT 
ACCCGGCTGG CTGGCGCAGG AACTCAGAAG AAGAGAGTTA GTTCTGCTTC ATGTCCCTCA 
AAATTTCAGA TTGTGGCCAA GGGCATGATA GCTCGGGGAG TTCCAGGAGC CATTGTGAAT 
GTCTCCAGCC AGGCCTCCCA ACGTGCACTG ACCAACCATA CTGTCTACTG TTCCACCAAG 
GGTGCTCTGG ACATGTTGAC CAAGATGATG GCCCTAGAGC TTGGGCCCCA CAAGATCCGT 
GTGAATGCAG TAAACCCCAC AGTAGTGATG ACACCCATGG GCCGGACCAA CTGGAGTGAC 
CCCCACAAAG CTAAGGCCAT GCTGGATCGT ATCCCACTGG GCAAGTTCGC TGAGGTGGAG 
AACGTCGTGG ACACCATTCT CTTCCTGCTG AGCAACCGGA GTGGCATGAC CACTGGCTCC 
ACTTTGCCAG TGGATGGGGG CTTCCTGGCT ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
The American journal of pathology186(11)2887-2908(2016 Nov)
Hubbs AF,Fluharty KL,Edwards RJ,Barnabei JL,Grantham JT,Palmer SM,Kelly F,Sargent LM,Reynolds SH,Mercer RR,Goravanahally MP,Kashon ML,Honaker JC,Jackson MC,Cumpston AM,Goldsmith WT,McKinney W,Fedan JS,Battelli LA,Munro T,Bucklew-Moyers W,McKinstry K,Schwegler-Berry D,Friend S,Knepp AK,Smith SL,Sriram K

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research26(7)1457-71(2011 Jul)
Abdallah BM,Ditzel N,Mahmood A,Isa A,Traustadottir GA,Schilling AF,Ruiz-Hidalgo MJ,Laborda J,Amling M,Kassem M

Transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-Ay diabetic model mice: an animal model for the metabolism of renal carbonyl compounds.
Experimental animals54(5)385-94(2005 Oct)
Sudo T,Ishii A,Asami J,Uematsu Y,Saitoh M,Nakamura A,Tada N,Ohnuki T,Komurasaki T,Nakagawa J

Quantitative trait loci for steady-state platelet count in mice.
Mammalian genome : official journal of the International Mammalian Genome Society15(10)784-97(2004 Oct)
Cheung CC,Martin IC,Zenger KR,Donald JA,Thomson PC,Moran C,Buckley MF

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Dcxr cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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