Rab32 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab32
Entrez Gene ID	67844
Full Name	RAB32, member RAS oncogene family
Synonyms	2810011A17Rik,AU022057
General protein information	Preferred Names RAB32, member RAS oncogene family Names ras-related protein Rab-32
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_026405.3	NP_080681.1	ras-related protein Rab-32

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	rab32a	NP_958489.1
Drosophila melanogaster (fruit fly)	ltd	NP_724763.1
Caenorhabditis elegans (roundworm)	glo-1	NP_001024837.1
Bos taurus (cattle)	RAB32	NP_001192879.1
Mus musculus (house mouse)	Rab32	NP_080681.1
Homo sapiens (human)	RAB32	NP_006825.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007654	XP_308216.2
	RAB32	XP_001090737.2
Gallus gallus (chicken)	RAB32	NP_001264601.1
Pan troglodytes (chimpanzee)	RAB32	XP_001161467.2
Canis lupus familiaris (dog)	RAB32	XP_005615551.1
Rattus norvegicus (Norway rat)	Rab32	NP_001102372.1
Xenopus tropicalis (tropical clawed frog)	rab32	NP_001011276.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP.
Span? S, Gao X, Hannemann S, Lara-Tejero M, Gal?n JE
Cell host & microbe19(2)216-26(2016 Feb)

Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.
Li Y, Wang Y, Zou L, Tang X, Yang Y, Ma L, Jia Q, Ni Q, Liu S, Tang L, Lin R, Wong E, Sun W, Wang L, Wei Q, Ran H, Zhang L, Lian H, Huang W, Wu Y, Li QJ, Wan Y
Immunity44(2)422-37(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rab32 represents a general cell-autonomous, antimicrobial defense that is counteracted by two Salmonella effectors.
Title: A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP.

antimicrobial functions in macromolecular complex results in bacterial containment
Title: Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.

Data suggest RUTBC1/SGSM2 in melanocytes functions as physiological GTPase-activating protein for Rab32/Rab38 in regulation of transport of melanogenic enzymes (tyrosinase, tyrosinase-related protein 1, dopachrome isomerase) into melanosomes.
Title: RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes.

Rab32 could improve the induction of iPSCs through the enhancement of lipid biosynthesis, highlighting the importance of lipid metabolism during reprogramming.
Title: Improvement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming.

RNA interference-mediated depletion of Rab32 or of an essential component of a BLOC complex was sufficient to allow S. Typhi to survive within mouse macrophages.
Title: A Rab32-dependent pathway contributes to Salmonella typhi host restriction.

The following Rab32 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab32 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02206	NM_026405.3 Latest version!	Mus musculus RAB32, member RAS oncogene family (Rab32), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab32 ( NM_026405.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080681.1 Mus musculus RAB32, member RAS oncogene family (Rab32), mRNA.

Price & Availability↑

CloneID	OMu02206
Clone ID Related Accession (Same CDS sequence)	NM_026405.3
Accession Version	NM_026405.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	ras-related protein Rab-32
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK088661.1. On Apr 5, 2007 this sequence version replaced NM_026405.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK088661.1, AK163620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCG AGGGACTAGG GCAACAGGGC GCGTCGGCCA CCGCGGCGCC GGAGACCCGA 
GAGCACCTCT TTAAGGTGCT GGTCATCGGC GAGCTCGGCG TGGGTAAGAC GAGCATCATC 
AAGCGCTACG TGCACCAGCT CTTCTCCCAG CACTACCGCG CCACCATTGG CGTGGACTTC 
GCCCTCAAAG TTCTCAACTG GGACAGCAGG ACGCTCGTGC GCCTGCAGCT GTGGGATATC 
GCGGGACAGG AACGGTTTGG CAACATGACT CGAGTATACT ATAAGGAAGC TCTTGGAGCA 
TTTGTAGTCT TTGATATATC GAGAAGTTCT ACATTTGATG CAGTCCTAAA ATGGAAAAAC 
GATCTGGATA GTAAAGTTCA TCTTCCCAAC GGCAGCCCCA TTCCTGCTGT CCTCCTAGCT 
AACAAATGTG ACCAGAAGAA GGACAACAGC CAGAGTCCTT CCCAGATGGA CCAGTTTTGT 
AAAGACCATG GCTTCACTGG ATGGTTTGAA ACCTCTGCCA AGGATAATAT AAACATCGAC 
GAGGCCACCC GCTTCCTAGT GGAAAACATG CTTGCAAACC AGCAAAGTTT TCCTAGTGAA 
GAAATCGACC TGGACAGAAT TAAACTGGTA GAGGAGCCCC CCACAACAAA GCCCAGGTCC 
CAGTGCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080681.1
CDS	120..791
Translation	MAGEGLGQQGASATAAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKKDNSQSPSQMDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFPSEEIDLDRIKLVEEPPTTKPRSQCC

Target ORF information:

RefSeq Version	NM_026405.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAB32, member RAS oncogene family (Rab32), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026405.3

ORF Insert Sequence:

ATGGCGGGCG AGGGACTAGG GCAACAGGGC GCGTCGGCCA CCGCGGCGCC GGAGACCCGA 
GAGCACCTCT TTAAGGTGCT GGTCATCGGC GAGCTCGGCG TGGGTAAGAC GAGCATCATC 
AAGCGCTACG TGCACCAGCT CTTCTCCCAG CACTACCGCG CCACCATTGG CGTGGACTTC 
GCCCTCAAAG TTCTCAACTG GGACAGCAGG ACGCTCGTGC GCCTGCAGCT GTGGGATATC 
GCGGGACAGG AACGGTTTGG CAACATGACT CGAGTATACT ATAAGGAAGC TCTTGGAGCA 
TTTGTAGTCT TTGATATATC GAGAAGTTCT ACATTTGATG CAGTCCTAAA ATGGAAAAAC 
GATCTGGATA GTAAAGTTCA TCTTCCCAAC GGCAGCCCCA TTCCTGCTGT CCTCCTAGCT 
AACAAATGTG ACCAGAAGAA GGACAACAGC CAGAGTCCTT CCCAGATGGA CCAGTTTTGT 
AAAGACCATG GCTTCACTGG ATGGTTTGAA ACCTCTGCCA AGGATAATAT AAACATCGAC 
GAGGCCACCC GCTTCCTAGT GGAAAACATG CTTGCAAACC AGCAAAGTTT TCCTAGTGAA 
GAAATCGACC TGGACAGAAT TAAACTGGTA GAGGAGCCCC CCACAACAAA GCCCAGGTCC 
CAGTGCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP.
Cell host & microbe19(2)216-26(2016 Feb)
Span? S,Gao X,Hannemann S,Lara-Tejero M,Gal?n JE

Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.
Immunity44(2)422-37(2016 Feb)
Li Y,Wang Y,Zou L,Tang X,Yang Y,Ma L,Jia Q,Ni Q,Liu S,Tang L,Lin R,Wong E,Sun W,Wang L,Wei Q,Ran H,Zhang L,Lian H,Huang W,Wu Y,Li QJ,Wan Y

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Rab32 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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