Retsat cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Retsat
Entrez Gene ID	67442
Full Name	retinol saturase (all trans retinol 13,14 reductase)
Synonyms	0610039N19Rik,C80029,MMT-7,Ppsig
General protein information	Preferred Names retinol saturase (all trans retinol 13,14 reductase) Names all-trans-retinol 13,14-reductase PPAR-alpha-regulated and starvation-induced gene protein all-trans-13,14-dihydroretinol saturase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_026159.4	NP_080435.3	all-trans-retinol 13,14-reductase precursor
NM_026159.5	NP_080435.3	all-trans-retinol 13,14-reductase precursor

Pathways from BioSystems

Homologies

	RETSAT	XP_001083594.1
Canis lupus familiaris (dog)	RETSAT	XP_540198.1
Bos taurus (cattle)	RETSAT	NP_001095749.2
Gallus gallus (chicken)	RETSAT	XP_424187.3
Oryza sativa (rice)	Os03g0841900	NP_001051855.1
Rattus norvegicus (Norway rat)	Retsat	NP_659552.1
Mus musculus (house mouse)	Retsat	NP_080435.3
Arabidopsis thaliana (thale cress)	AT1G57770	NP_176088.2
Xenopus tropicalis (tropical clawed frog)	retsat	NP_001121412.1
Danio rerio (zebrafish)	retsat	NP_001015061.1
Homo sapiens (human)	RETSAT	NP_060220.3
Pan troglodytes (chimpanzee)	RETSAT	XP_525801.2
Danio rerio (zebrafish)	zgc:154169	NP_001071261.1

Gene Ontology
Bibliography

Related articles in PubMed

Retinol saturase modulates lipid metabolism and the production of reactive oxygen species.
Pang XY, Wang S, Jurczak MJ, Shulman GI, Moise AR
Archives of biochemistry and biophysics63393-102(2017 Nov)

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH
Proceedings of the National Academy of Sciences of the United States of America114(8)E1432-E1440(2017 02)

Genetic variations strongly influence phenotypic outcome in the mouse retina.
Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB
PloS one6(7)e21858(2011)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

Increased adiposity in the retinol saturase-knockout mouse.
Moise AR, Lobo GP, Erokwu B, Wilson DL, Peck D, Alvarez S, Dom?nguez M, Alvarez R, Flask CA, de Lera AR, von Lintig J, Palczewski K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology24(4)1261-70(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Retsat modulates lipid metabolism and the production of reactive oxygen species.
Title: Retinol saturase modulates lipid metabolism and the production of reactive oxygen species.

RetSat-deficiency is associated with alterations in lipid metabolism and the in vivo adipogenic program.
Title: Increased adiposity in the retinol saturase-knockout mouse.

RetSat plays an important role in the biology of adipocytes, where it favors normal differentiation, yet is reduced in the obese state.
Title: Retinol saturase promotes adipogenesis and is downregulated in obesity.

Mouse RetSat catalyzes the stereospecific saturation of the C13-C14 double bond of all-trans-retinol to produce (13R)-all-trans-13,14-dihydroretinol.
Title: Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids.

Here, we report the identification and characterization of Ppsig (for PPARalpha-regulated and starvation-induced gene) with unknown biological function from mouse liver
Title: Identification and characterization of a novel mouse peroxisome proliferator-activated receptor alpha-regulated and starvation-induced gene, Ppsig.

The following Retsat gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Retsat cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01704	NM_026159.5 Latest version!	Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$356.30 $509.00
View Old Accession Versions >>
OMu01704	NM_026159.4	Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$356.30 $509.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Retsat ( NM_026159.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080435.3 Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.

Price & Availability↑

CloneID	OMu01704
Clone ID Related Accession (Same CDS sequence)	NM_026159.4 , NM_026159.5
Accession Version	NM_026159.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	all-trans-retinol 13,14-reductase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY704159.1 and AI020794.1. On Feb 8, 2006 this sequence version replaced NM_026159.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF620365.1, AK144115.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGATCA CTGCTCTGCT GCTGGCCGTG CTGCTGCTGG TGATCCTCCA CAGGGTCTAC 
GTGGGCCTTT ACGCTGCAAG TTCCCCGAAC CCCTTCGCCG AGGATGTCAA GCGACCGCCT 
GAACCCCTGG TGACCGACAA GGAGGCTAGG AAGAAAGTTC TCAAACAAGC TTTCTCAGTC 
AGCCGAGTAC CAGAGAAGCT GGATGCAGTG GTGATCGGCA GCGGCATTGG GGGACTGGCC 
TCAGCTGCGG TTCTAGCTAA AGCTGGCAAG AGAGTCCTTG TGCTGGAACA ACATACCAAG 
GCGGGCGGCT GTTGTCATAC CTTTGGGGAA AATGGCCTTG AATTTGACAC TGGAATTCAT 
TATATTGGAC GAATGCGGGA GGGCAACATT GGCCGTTTTA TCTTGGACCA GATCACTGAA 
GGGCAACTGG ACTGGGCCCC CATGGCCTCC CCTTTTGACT TGATGATACT AGAAGGGCCC 
AATGGCCGAA AGGAGTTCCC CATGTACAGT GGGAGGAAAG AATACATCCA GGGCCTTAAG 
AAGAAGTTCC CCAAGGAAGA AGCTGTCATT GACAAGTACA TGGAGTTGGT TAAGGTGGTG 
GCCCGTGGAG TCTCTCATGC AGTTCTACTC AAGTTCCTCC CATTGCCCTT GACTCAGCTC 
CTCAGCAAGT TTGGGCTACT GACTCGTTTC TCTCCATTCT GCCGAGCGTC TACGCAGAGC 
CTAGCTGAAG TCCTGCAGCA GCTTGGGGCT TCCCGTGAGC TCCAGGCTGT TCTCAGCTAC 
ATCTTCCCCA CTTACGGAGT AACTCCCAGC CACACCGCCT TTTCCTTGCA TGCTCTGCTG 
GTTGACCACT ACATACAAGG GGCATATTAC CCTCGAGGGG GTTCCAGTGA GATCGCCTTC 
CATACCATCC CTTTGATTCA GCGGGCCGGG GGCGCTGTCC TCACCAGGGC CACTGTACAG 
AGTGTGCTGC TGGACTCAGC TGGGAGAGCG TGTGGTGTCA GTGTGAAGAA GGGACAAGAG 
CTGGTGAACA TCTACTGCCC AGTTGTCATC TCCAATGCGG GAATGTTCAA TACCTATCAG 
CACTTGTTGC CAGAGACTGT CCGCCATCTG CCAGATGTGA AGAAGCAGCT GGCGATGGTA 
AGGCCTGGTC TGAGCATGCT CTCAATCTTC ATCTGTCTGA AAGGCACCAA GGAGGACCTG 
AAGCTTCAGT CCACCAACTA CTATGTTTAT TTTGACACAG ACATGGACAA AGCGATGGAG 
CGCTATGTCT CTATGCCCAA GGAAAAGGCT CCAGAACACA TTCCCCTTCT CTTCATTGCC 
TTCCCATCAA GCAAGGATCC AACCTGGGAG GAGCGATTCC CAGACCGATC CACAATGACT 
GCGCTGGTAC CCATGGCCTT TGAATGGTTC GAGGAGTGGC AGGAGGAGCC AAAGGGCAAG 
CGTGGTGTTG ACTATGAGAC CCTCAAAAAT GCCTTCGTGG AAGCCTCTAT GTCGGTGATC 
ATGAAACTGT TCCCACAGCT GGAGGGCAAG GTGGAGAGTG TGACTGGAGG GTCACCACTG 
ACCAACCAGT ACTATCTGGC TGCACCCCGA GGAGCTACCT ATGGAGCTGA CCATGACTTG 
GCTCGGCTGC ATCCTCATGC AATGGCTTCC ATAAGAGCCC AAACCCCCAT CCCCAACCTC 
TACCTGACAG GCCAAGATAT CTTCACCTGT GGGCTGATGG GGGCCCTGCA GGGGGCCTTG 
CTGTGCAGCA GTGCCATCCT GAAACGGAAC TTGTACTCAG ATCTGCAGGC TCTTGGCTCA 
AAGGTCAAGG CACAAAAGAA GAAGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080435.3
CDS	1..1830
Translation	MWITALLLAVLLLVILHRVYVGLYAASSPNPFAEDVKRPPEPLVTDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAGGCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGPNGRKEFPMYSGRKEYIQGLKKKFPKEEAVIDKYMELVKVVARGVSHAVLLKFLPLPLTQLLSKFGLLTRFSPFCRASTQSLAEVLQQLGASRELQAVLSYIFPTYGVTPSHTAFSLHALLVDHYIQGAYYPRGGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVSVKKGQELVNIYCPVVISNAGMFNTYQHLLPETVRHLPDVKKQLAMVRPGLSMLSIFICLKGTKEDLKLQSTNYYVYFDTDMDKAMERYVSMPKEKAPEHIPLLFIAFPSSKDPTWEERFPDRSTMTALVPMAFEWFEEWQEEPKGKRGVDYETLKNAFVEASMSVIMKLFPQLEGKVESVTGGSPLTNQYYLAAPRGATYGADHDLARLHPHAMASIRAQTPIPNLYLTGQDIFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVKAQKKKM

Target ORF information:

RefSeq Version	NM_026159.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026159.4

ORF Insert Sequence:

ATGTGGATCA CTGCTCTGCT GCTGGCCGTG CTGCTGCTGG TGATCCTCCA CAGGGTCTAC 
GTGGGCCTTT ACGCTGCAAG TTCCCCGAAC CCCTTCGCCG AGGATGTCAA GCGACCGCCT 
GAACCCCTGG TGACCGACAA GGAGGCTAGG AAGAAAGTTC TCAAACAAGC TTTCTCAGTC 
AGCCGAGTAC CAGAGAAGCT GGATGCAGTG GTGATCGGCA GCGGCATTGG GGGACTGGCC 
TCAGCTGCGG TTCTAGCTAA AGCTGGCAAG AGAGTCCTTG TGCTGGAACA ACATACCAAG 
GCGGGCGGCT GTTGTCATAC CTTTGGGGAA AATGGCCTTG AATTTGACAC TGGAATTCAT 
TATATTGGAC GAATGCGGGA GGGCAACATT GGCCGTTTTA TCTTGGACCA GATCACTGAA 
GGGCAACTGG ACTGGGCCCC CATGGCCTCC CCTTTTGACT TGATGATACT AGAAGGGCCC 
AATGGCCGAA AGGAGTTCCC CATGTACAGT GGGAGGAAAG AATACATCCA GGGCCTTAAG 
AAGAAGTTCC CCAAGGAAGA AGCTGTCATT GACAAGTACA TGGAGTTGGT TAAGGTGGTG 
GCCCGTGGAG TCTCTCATGC AGTTCTACTC AAGTTCCTCC CATTGCCCTT GACTCAGCTC 
CTCAGCAAGT TTGGGCTACT GACTCGTTTC TCTCCATTCT GCCGAGCGTC TACGCAGAGC 
CTAGCTGAAG TCCTGCAGCA GCTTGGGGCT TCCCGTGAGC TCCAGGCTGT TCTCAGCTAC 
ATCTTCCCCA CTTACGGAGT AACTCCCAGC CACACCGCCT TTTCCTTGCA TGCTCTGCTG 
GTTGACCACT ACATACAAGG GGCATATTAC CCTCGAGGGG GTTCCAGTGA GATCGCCTTC 
CATACCATCC CTTTGATTCA GCGGGCCGGG GGCGCTGTCC TCACCAGGGC CACTGTACAG 
AGTGTGCTGC TGGACTCAGC TGGGAGAGCG TGTGGTGTCA GTGTGAAGAA GGGACAAGAG 
CTGGTGAACA TCTACTGCCC AGTTGTCATC TCCAATGCGG GAATGTTCAA TACCTATCAG 
CACTTGTTGC CAGAGACTGT CCGCCATCTG CCAGATGTGA AGAAGCAGCT GGCGATGGTA 
AGGCCTGGTC TGAGCATGCT CTCAATCTTC ATCTGTCTGA AAGGCACCAA GGAGGACCTG 
AAGCTTCAGT CCACCAACTA CTATGTTTAT TTTGACACAG ACATGGACAA AGCGATGGAG 
CGCTATGTCT CTATGCCCAA GGAAAAGGCT CCAGAACACA TTCCCCTTCT CTTCATTGCC 
TTCCCATCAA GCAAGGATCC AACCTGGGAG GAGCGATTCC CAGACCGATC CACAATGACT 
GCGCTGGTAC CCATGGCCTT TGAATGGTTC GAGGAGTGGC AGGAGGAGCC AAAGGGCAAG 
CGTGGTGTTG ACTATGAGAC CCTCAAAAAT GCCTTCGTGG AAGCCTCTAT GTCGGTGATC 
ATGAAACTGT TCCCACAGCT GGAGGGCAAG GTGGAGAGTG TGACTGGAGG GTCACCACTG 
ACCAACCAGT ACTATCTGGC TGCACCCCGA GGAGCTACCT ATGGAGCTGA CCATGACTTG 
GCTCGGCTGC ATCCTCATGC AATGGCTTCC ATAAGAGCCC AAACCCCCAT CCCCAACCTC 
TACCTGACAG GCCAAGATAT CTTCACCTGT GGGCTGATGG GGGCCCTGCA GGGGGCCTTG 
CTGTGCAGCA GTGCCATCCT GAAACGGAAC TTGTACTCAG ATCTGCAGGC TCTTGGCTCA 
AAGGTCAAGG CACAAAAGAA GAAGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Retsat ( NM_026159.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080435.3 Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.

Price & Availability↑

CloneID	OMu01704
Clone ID Related Accession (Same CDS sequence)	NM_026159.4 , NM_026159.5
Accession Version	NM_026159.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-25
Organism	Mus musculus(house mouse)
Product	all-trans-retinol 13,14-reductase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC125039.4. On Jun 26, 2019 this sequence version replaced NM_026159.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF620365.1, SRR5189682.111646.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGATCA CTGCTCTGCT GCTGGCCGTG CTGCTGCTGG TGATCCTCCA CAGGGTCTAC 
GTGGGCCTTT ACGCTGCAAG TTCCCCGAAC CCCTTCGCCG AGGATGTCAA GCGACCGCCT 
GAACCCCTGG TGACCGACAA GGAGGCTAGG AAGAAAGTTC TCAAACAAGC TTTCTCAGTC 
AGCCGAGTAC CAGAGAAGCT GGATGCAGTG GTGATCGGCA GCGGCATTGG GGGACTGGCC 
TCAGCTGCGG TTCTAGCTAA AGCTGGCAAG AGAGTCCTTG TGCTGGAACA ACATACCAAG 
GCGGGCGGCT GTTGTCATAC CTTTGGGGAA AATGGCCTTG AATTTGACAC TGGAATTCAT 
TATATTGGAC GAATGCGGGA GGGCAACATT GGCCGTTTTA TCTTGGACCA GATCACTGAA 
GGGCAACTGG ACTGGGCCCC CATGGCCTCC CCTTTTGACT TGATGATACT AGAAGGGCCC 
AATGGCCGAA AGGAGTTCCC CATGTACAGT GGGAGGAAAG AATACATCCA GGGCCTTAAG 
AAGAAGTTCC CCAAGGAAGA AGCTGTCATT GACAAGTACA TGGAGTTGGT TAAGGTGGTG 
GCCCGTGGAG TCTCTCATGC AGTTCTACTC AAGTTCCTCC CATTGCCCTT GACTCAGCTC 
CTCAGCAAGT TTGGGCTACT GACTCGTTTC TCTCCATTCT GCCGAGCGTC TACGCAGAGC 
CTAGCTGAAG TCCTGCAGCA GCTTGGGGCT TCCCGTGAGC TCCAGGCTGT TCTCAGCTAC 
ATCTTCCCCA CTTACGGAGT AACTCCCAGC CACACCGCCT TTTCCTTGCA TGCTCTGCTG 
GTTGACCACT ACATACAAGG GGCATATTAC CCTCGAGGGG GTTCCAGTGA GATCGCCTTC 
CATACCATCC CTTTGATTCA GCGGGCCGGG GGCGCTGTCC TCACCAGGGC CACTGTACAG 
AGTGTGCTGC TGGACTCAGC TGGGAGAGCG TGTGGTGTCA GTGTGAAGAA GGGACAAGAG 
CTGGTGAACA TCTACTGCCC AGTTGTCATC TCCAATGCGG GAATGTTCAA TACCTATCAG 
CACTTGTTGC CAGAGACTGT CCGCCATCTG CCAGATGTGA AGAAGCAGCT GGCGATGGTA 
AGGCCTGGTC TGAGCATGCT CTCAATCTTC ATCTGTCTGA AAGGCACCAA GGAGGACCTG 
AAGCTTCAGT CCACCAACTA CTATGTTTAT TTTGACACAG ACATGGACAA AGCGATGGAG 
CGCTATGTCT CTATGCCCAA GGAAAAGGCT CCAGAACACA TTCCCCTTCT CTTCATTGCC 
TTCCCATCAA GCAAGGATCC AACCTGGGAG GAGCGATTCC CAGACCGATC CACAATGACT 
GCGCTGGTAC CCATGGCCTT TGAATGGTTC GAGGAGTGGC AGGAGGAGCC AAAGGGCAAG 
CGTGGTGTTG ACTATGAGAC CCTCAAAAAT GCCTTCGTGG AAGCCTCTAT GTCGGTGATC 
ATGAAACTGT TCCCACAGCT GGAGGGCAAG GTGGAGAGTG TGACTGGAGG GTCACCACTG 
ACCAACCAGT ACTATCTGGC TGCACCCCGA GGAGCTACCT ATGGAGCTGA CCATGACTTG 
GCTCGGCTGC ATCCTCATGC AATGGCTTCC ATAAGAGCCC AAACCCCCAT CCCCAACCTC 
TACCTGACAG GCCAAGATAT CTTCACCTGT GGGCTGATGG GGGCCCTGCA GGGGGCCTTG 
CTGTGCAGCA GTGCCATCCT GAAACGGAAC TTGTACTCAG ATCTGCAGGC TCTTGGCTCA 
AAGGTCAAGG CACAAAAGAA GAAGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080435.3
CDS	27..1856
Translation	MWITALLLAVLLLVILHRVYVGLYAASSPNPFAEDVKRPPEPLVTDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAGGCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGPNGRKEFPMYSGRKEYIQGLKKKFPKEEAVIDKYMELVKVVARGVSHAVLLKFLPLPLTQLLSKFGLLTRFSPFCRASTQSLAEVLQQLGASRELQAVLSYIFPTYGVTPSHTAFSLHALLVDHYIQGAYYPRGGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVSVKKGQELVNIYCPVVISNAGMFNTYQHLLPETVRHLPDVKKQLAMVRPGLSMLSIFICLKGTKEDLKLQSTNYYVYFDTDMDKAMERYVSMPKEKAPEHIPLLFIAFPSSKDPTWEERFPDRSTMTALVPMAFEWFEEWQEEPKGKRGVDYETLKNAFVEASMSVIMKLFPQLEGKVESVTGGSPLTNQYYLAAPRGATYGADHDLARLHPHAMASIRAQTPIPNLYLTGQDIFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVKAQKKKM

Target ORF information:

RefSeq Version	NM_026159.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026159.5

ORF Insert Sequence:

ATGTGGATCA CTGCTCTGCT GCTGGCCGTG CTGCTGCTGG TGATCCTCCA CAGGGTCTAC 
GTGGGCCTTT ACGCTGCAAG TTCCCCGAAC CCCTTCGCCG AGGATGTCAA GCGACCGCCT 
GAACCCCTGG TGACCGACAA GGAGGCTAGG AAGAAAGTTC TCAAACAAGC TTTCTCAGTC 
AGCCGAGTAC CAGAGAAGCT GGATGCAGTG GTGATCGGCA GCGGCATTGG GGGACTGGCC 
TCAGCTGCGG TTCTAGCTAA AGCTGGCAAG AGAGTCCTTG TGCTGGAACA ACATACCAAG 
GCGGGCGGCT GTTGTCATAC CTTTGGGGAA AATGGCCTTG AATTTGACAC TGGAATTCAT 
TATATTGGAC GAATGCGGGA GGGCAACATT GGCCGTTTTA TCTTGGACCA GATCACTGAA 
GGGCAACTGG ACTGGGCCCC CATGGCCTCC CCTTTTGACT TGATGATACT AGAAGGGCCC 
AATGGCCGAA AGGAGTTCCC CATGTACAGT GGGAGGAAAG AATACATCCA GGGCCTTAAG 
AAGAAGTTCC CCAAGGAAGA AGCTGTCATT GACAAGTACA TGGAGTTGGT TAAGGTGGTG 
GCCCGTGGAG TCTCTCATGC AGTTCTACTC AAGTTCCTCC CATTGCCCTT GACTCAGCTC 
CTCAGCAAGT TTGGGCTACT GACTCGTTTC TCTCCATTCT GCCGAGCGTC TACGCAGAGC 
CTAGCTGAAG TCCTGCAGCA GCTTGGGGCT TCCCGTGAGC TCCAGGCTGT TCTCAGCTAC 
ATCTTCCCCA CTTACGGAGT AACTCCCAGC CACACCGCCT TTTCCTTGCA TGCTCTGCTG 
GTTGACCACT ACATACAAGG GGCATATTAC CCTCGAGGGG GTTCCAGTGA GATCGCCTTC 
CATACCATCC CTTTGATTCA GCGGGCCGGG GGCGCTGTCC TCACCAGGGC CACTGTACAG 
AGTGTGCTGC TGGACTCAGC TGGGAGAGCG TGTGGTGTCA GTGTGAAGAA GGGACAAGAG 
CTGGTGAACA TCTACTGCCC AGTTGTCATC TCCAATGCGG GAATGTTCAA TACCTATCAG 
CACTTGTTGC CAGAGACTGT CCGCCATCTG CCAGATGTGA AGAAGCAGCT GGCGATGGTA 
AGGCCTGGTC TGAGCATGCT CTCAATCTTC ATCTGTCTGA AAGGCACCAA GGAGGACCTG 
AAGCTTCAGT CCACCAACTA CTATGTTTAT TTTGACACAG ACATGGACAA AGCGATGGAG 
CGCTATGTCT CTATGCCCAA GGAAAAGGCT CCAGAACACA TTCCCCTTCT CTTCATTGCC 
TTCCCATCAA GCAAGGATCC AACCTGGGAG GAGCGATTCC CAGACCGATC CACAATGACT 
GCGCTGGTAC CCATGGCCTT TGAATGGTTC GAGGAGTGGC AGGAGGAGCC AAAGGGCAAG 
CGTGGTGTTG ACTATGAGAC CCTCAAAAAT GCCTTCGTGG AAGCCTCTAT GTCGGTGATC 
ATGAAACTGT TCCCACAGCT GGAGGGCAAG GTGGAGAGTG TGACTGGAGG GTCACCACTG 
ACCAACCAGT ACTATCTGGC TGCACCCCGA GGAGCTACCT ATGGAGCTGA CCATGACTTG 
GCTCGGCTGC ATCCTCATGC AATGGCTTCC ATAAGAGCCC AAACCCCCAT CCCCAACCTC 
TACCTGACAG GCCAAGATAT CTTCACCTGT GGGCTGATGG GGGCCCTGCA GGGGGCCTTG 
CTGTGCAGCA GTGCCATCCT GAAACGGAAC TTGTACTCAG ATCTGCAGGC TCTTGGCTCA 
AAGGTCAAGG CACAAAAGAA GAAGATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Retinol saturase modulates lipid metabolism and the production of reactive oxygen species.
Archives of biochemistry and biophysics63393-102(2017 Nov)
Pang XY,Wang S,Jurczak MJ,Shulman GI,Moise AR

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Proceedings of the National Academy of Sciences of the United States of America114(8)E1432-E1440(2017 02)
Chen S,Lu W,Yueh MF,Rettenmeier E,Liu M,Auwerx J,Yu RT,Evans RM,Wang K,Karin M,Tukey RH

Genetic variations strongly influence phenotypic outcome in the mouse retina.
PloS one6(7)e21858(2011)
Jelcick AS,Yuan Y,Leehy BD,Cox LC,Silveira AC,Qiu F,Schenk S,Sachs AJ,Morrison MA,Nystuen AM,DeAngelis MM,Haider NB

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

Increased adiposity in the retinol saturase-knockout mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology24(4)1261-70(2010 Apr)
Moise AR,Lobo GP,Erokwu B,Wilson DL,Peck D,Alvarez S,Dom?nguez M,Alvarez R,Flask CA,de Lera AR,von Lintig J,Palczewski K

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Retsat cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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