Smc6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Smc6
Entrez Gene ID	67241
Full Name	structural maintenance of chromosomes 6
Synonyms	2810489L22Rik,3830418C19Rik,AA990493,AU018782,AW742439,SMC-6,Smc6l1,mKIAA4103
General protein information	Preferred Names structural maintenance of chromosomes 6 Names structural maintenance of chromosomes protein 6 SMC protein 6 SMC6 structural maintenance of chromosomes 6-like 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006515173.2	XP_006515236.1	structural maintenance of chromosomes protein 6 isoform X1
NM_001361252.1	NP_001348181.1	structural maintenance of chromosomes protein 6 isoform 3
XM_011243892.2	XP_011242194.1	structural maintenance of chromosomes protein 6 isoform X2
NM_025695.4	NP_079971.2	structural maintenance of chromosomes protein 6 isoform 1
NM_001324476.1	NP_001311405.1	structural maintenance of chromosomes protein 6 isoform 2
XM_006515173.3	XP_006515236.1	structural maintenance of chromosomes protein 6 isoform X1
XM_011243892.3	XP_011242194.1	structural maintenance of chromosomes protein 6 isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SMC6	XP_002691521.2
Danio rerio (zebrafish)	si:dkey-119f1.1	NP_001121806.1
Arabidopsis thaliana (thale cress)	SMC6A	NP_196383.1
Pan troglodytes (chimpanzee)	SMC6	XP_001136387.1
Arabidopsis thaliana (thale cress)	MIM	NP_200954.1
Oryza sativa (rice)	Os09g0121000	NP_001175716.1
Xenopus tropicalis (tropical clawed frog)	LOC100495796	XP_004918254.1
Xenopus tropicalis (tropical clawed frog)	LOC100496941	XP_002934531.2
Xenopus tropicalis (tropical clawed frog)	LOC100495634	XP_004918255.1
Homo sapiens (human)	SMC6	NP_078900.1
Canis lupus familiaris (dog)	SMC6	XP_005630207.1
Gallus gallus (chicken)	SMC6	XP_004935838.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002985	XP_311902.4
Mus musculus (house mouse)	Smc6	NP_079971.2
Drosophila melanogaster (fruit fly)	CG5524	NP_651228.1
Rattus norvegicus (Norway rat)	Smc6	NP_001101484.1

Gene Ontology
Bibliography

Related articles in PubMed

SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.
Hwang G, Sun F, O'Brien M, Eppig JJ, Handel MA, Jordan PW
Development (Cambridge, England)144(9)1648-1660(2017 05)

Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.
Verver DE, van Pelt AM, Repping S, Hamer G
Cell death & disease4e749(2013 Aug)

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.
Ju L, Wing J, Taylor E, Brandt R, Slijepcevic P, Horsch M, Rathkolb B, R?cz I, Becker L, Hans W, Adler T, Beckers J, Rozman J, Klingenspor M, Wolf E, Zimmer A, Klopstock T, Busch DH, Gailus-Durner V, Fuchs H, de Angelis MH, van der Horst G, Lehmann AR
DNA repair12(5)356-66(2013 May)

Telomeric DNA mediates de novo PML body formation.
Brouwer AK, Schimmel J, Wiegant JC, Vertegaal AC, Tanke HJ, Dirks RW
Molecular biology of the cell20(22)4804-15(2009 Nov)

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.
Taylor EM, Moghraby JS, Lees JH, Smit B, Moens PB, Lehmann AR
Molecular biology of the cell12(6)1583-94(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

age-dependent depletion of the SMC5/6 complex in oocytes could contribute to increased incidence of oocyte aneuploidy and spontaneous abortion in aging females.
Title: SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.

Smc6 has a role in the prevention of aberrant recombination events between pericentromeric regions during the first meiotic prophase.
Title: Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.

Mice deleted for the SMC6 gene are inviable, and mice mutated at Ser-994 in the SMC6 ATPase domain have a mild phenotype.
Title: SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.

The following Smc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Smc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu47377	NM_001324476.1 Latest version!	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
OMu84264	NM_001361252.1 Latest version!	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu70104	XM_011243892.3 Latest version!	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu47376	XM_006515173.3 Latest version!	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu13640	NM_025695.4 Latest version!	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OMu47376	XM_006515173.2	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OMu70104	XM_011243892.2	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Smc6 ( NM_001324476.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001311405.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu47377
Clone ID Related Accession (Same CDS sequence)	NM_001324476.1
Accession Version	NM_001324476.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2700bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090630.1 and AK220488.1. On May 7, 2016 this sequence version replaced XM_006515174.2. ##Evidence-Data-START## Transcript exon combination :: AK220488.1, SRR1660819.39983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAAGC AGTTCTTACA GTCCAAAAAT GAGGGAGACA AATACAAATT CTTCATGAAA 
GCAACCCAGC TCGAACAGAT GAAGGAAGAT TATTCATATA TTATGGAAAC AAAAGAAAGA 
ACAAAGGAAC AAATAAATCA GGGAGAAGAG CGACTTACTG AACTAAAACG CCAGTGTTTG 
GAGAAAGAGG AACGTTTTCA AAATATTGCT GGTTTAAGTA CAATGAAGAC TAATTTAGAG 
TACTTGAAAC ATGAAATGGC TTGGGCAGTG GTCAATGAAA TTGAAAAACA ATTGAATGCT 
ATTCGAGACA ATATCAAAAT TGGAGAAGAA CGTGCTGCAA AACTTGACAG GAAAATGGAA 
GAGCAGCAGG TCAGACTTAA TGATGCAGAA AAAAAGTACA AAGATATACA AGATAAACTA 
GAAAAAATTA GTGAAGAGAC AAATGCACGA GCACCAGAAT GTATGGCATT GAAAACAGAT 
GTCATTGCAA GGACAAGAGC CTTTAATGAC GCTGAGGTTT TATATAACCG TTCCCTAAAT 
GAATATAAAG CATTAAAAAA AGATGGTGAA CAGCTTTGTA AAAGAATTGA AGAACTGAAG 
AAAAGTACTG ATCAGTCATT AGAACCAGAG CGATTGGAAA GGCAAAAAAG GATCTGCTGG 
TTAAAAGAGA AAGTCAAGGC CTTACAGGAT CAGGAACATA CAGTCAATCA GGAGGCTGAG 
CAGTTTGAGC AAGCCATAGA AAAGGACAAG CAAGAGCATG GCCGAGTTAG GAAAGAAGAT 
ATAGAAGTGA GACATGCACT CAACTATAAT CAGAGACAAT TGAAAGAACT GAAAGATAGT 
AAAACTGATC GACTAAAAAG ATTTGGTCCT CATGTTCCAG CTCTTCTGGA AGCAATAGAT 
GATGCTTACA GACGGAGACA ATTTACCCAT AAACCTATCG GCCCTTTAGG TGCTTGCATT 
CATCTACGGG ACCCTGAACT TGCTTTGGCC ATTGAATCTT GCTTAAAAGG ACTTCTGCAA 
GCCTATTGTT GCCATAATCA TGCTGATGAG AGAGTACTTC AGTCTTTGAT GAAAAAATTT 
TATCCACCAG GGACCTCTCG GCCACAGATA ATTGTGTCTG AGTTTCGGGA TGAGGTATAT 
GATGTGAGAC TCAGAGCTGC TTACCATCCA GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA 
ATAGACAATG CTGTTGTGGC AAACAGCCTG ATTGACATGC GGAGCATAGA GACAGTGCTG 
CTGATCAAAA ATAATTCTGT GGCTCGTGCA GTCATGCAAT CCCAAAAGCC ACCCAAAAAT 
TGTAGAGAAG CTTTTACTGC TGATGGTGAT CAAGTGTTTG CAGGACGTTA TTATTCATCT 
GAAAGTACAA GACCCAAGTT TCTAAGCAGA GATGTGGATT CTGAAATAAG TGACTTGGAG 
ACTGAGATTG AAAATAAAAA GGGCCACATA ATAACCCTTC AGCAGCGTCT GTCTGCGCTT 
GAGAAGGATA TCAAACGCAA TGAAGAACTT CTTAAAAGGT GCCAACTACA TTATAAAGAA 
ATAAAGATGA AAATAAGAAA AAATATTTCT GAAATTCGGG AACTTGAGAA TATAGAAGAA 
CACCAATCTG TAGATATTGC AACCTTGGAA GATGAAGCTG AAGAAAATAA AATAAAAATG 
CAAATGGTGG AGAAAAATAT GGAACAACAA AAAGAAAACA TGGAGAATCT TAAAAGTCTA 
AAAATTGAAG CAGAAAATAA GTATGATACA ATTAAATTGA AGATTAATCA GCTATCAGAG 
CTAGCGGATC CACTTAAGGA TGAGTTAAAT CTTGCTGACT CTGAAGTGGA TAGCCAGAAA 
CGAGGAAAGC AGCACTATGA GGATAAACAG AAAGAGCATT TGGATACCTT AAATAAAAAG 
AGACGAGAGC TTGACATGAA GGAAAAGGAG TTACAGGAGA AAATGTCACA GGCAAGACAG 
ATCTGCCCAG AACGGATAGA AGTAAAAAAA TCTGCATCAA TTCTAGACAA AGAAATAAAT 
CGATTAAGAC AAAAAATTCA GGCAGAACAT GCCAGTCATG GAGATCGGGA GGAAATAATG 
AAGCAGTATC AAGAAGCAAG AGAAACCTAC CTTGATCTGG ATAATAAAGT AAGGACTTTA 
AGAAGGTTCA TTAAATTGCT AGAAGAAATA ATGACCCATA GGTACAAAAC ATACCAACAA 
TTTAGAAGGT GTTTGACATT ACGATGCAAA TTATACTTTG ACAACTTATT ATCTCAGCGT 
GCTTATTGTG GAAAAATGAA TTTTGATCAC AAGAATGAAA CTCTTAGTAT AACAGTTCAG 
CCCGGAGAGG GGAACAAAGC CTCCTTCAAT GACATGCGTG CTTTGTCCGG CGGTGAGCGC 
TCTTTCTCCA CCGTGTGCTT CATCCTTTCC CTGTGGTCCA TTGCTGAATC ACCTTTCAGA 
TGCCTGGATG AGTTTGATGT CTACATGGAT ATGGTTAATA GGAGAATTGC GATGGACATG 
ATCCTTAAGA TGGCAGATTC CCAACGTTTT AGACAATTTA TCTTGCTTAC CCCTCAAAGC 
ATGAGCTCCC TTCCCTCAAG TAAACTGATT AGAATTCTTC GAATGTCTGA CCCTGAAAGA 
GGGCAAACCA CACTGCCCTT CCGACCTGTG ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311405.1
CDS	897..3596
Translation	MSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	NM_001324476.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324476.1

ORF Insert Sequence:

ATGAGCAAGC AGTTCTTACA GTCCAAAAAT GAGGGAGACA AATACAAATT CTTCATGAAA 
GCAACCCAGC TCGAACAGAT GAAGGAAGAT TATTCATATA TTATGGAAAC AAAAGAAAGA 
ACAAAGGAAC AAATAAATCA GGGAGAAGAG CGACTTACTG AACTAAAACG CCAGTGTTTG 
GAGAAAGAGG AACGTTTTCA AAATATTGCT GGTTTAAGTA CAATGAAGAC TAATTTAGAG 
TACTTGAAAC ATGAAATGGC TTGGGCAGTG GTCAATGAAA TTGAAAAACA ATTGAATGCT 
ATTCGAGACA ATATCAAAAT TGGAGAAGAA CGTGCTGCAA AACTTGACAG GAAAATGGAA 
GAGCAGCAGG TCAGACTTAA TGATGCAGAA AAAAAGTACA AAGATATACA AGATAAACTA 
GAAAAAATTA GTGAAGAGAC AAATGCACGA GCACCAGAAT GTATGGCATT GAAAACAGAT 
GTCATTGCAA GGACAAGAGC CTTTAATGAC GCTGAGGTTT TATATAACCG TTCCCTAAAT 
GAATATAAAG CATTAAAAAA AGATGGTGAA CAGCTTTGTA AAAGAATTGA AGAACTGAAG 
AAAAGTACTG ATCAGTCATT AGAACCAGAG CGATTGGAAA GGCAAAAAAG GATCTGCTGG 
TTAAAAGAGA AAGTCAAGGC CTTACAGGAT CAGGAACATA CAGTCAATCA GGAGGCTGAG 
CAGTTTGAGC AAGCCATAGA AAAGGACAAG CAAGAGCATG GCCGAGTTAG GAAAGAAGAT 
ATAGAAGTGA GACATGCACT CAACTATAAT CAGAGACAAT TGAAAGAACT GAAAGATAGT 
AAAACTGATC GACTAAAAAG ATTTGGTCCT CATGTTCCAG CTCTTCTGGA AGCAATAGAT 
GATGCTTACA GACGGAGACA ATTTACCCAT AAACCTATCG GCCCTTTAGG TGCTTGCATT 
CATCTACGGG ACCCTGAACT TGCTTTGGCC ATTGAATCTT GCTTAAAAGG ACTTCTGCAA 
GCCTATTGTT GCCATAATCA TGCTGATGAG AGAGTACTTC AGTCTTTGAT GAAAAAATTT 
TATCCACCAG GGACCTCTCG GCCACAGATA ATTGTGTCTG AGTTTCGGGA TGAGGTATAT 
GATGTGAGAC TCAGAGCTGC TTACCATCCA GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA 
ATAGACAATG CTGTTGTGGC AAACAGCCTG ATTGACATGC GGAGCATAGA GACAGTGCTG 
CTGATCAAAA ATAATTCTGT GGCTCGTGCA GTCATGCAAT CCCAAAAGCC ACCCAAAAAT 
TGTAGAGAAG CTTTTACTGC TGATGGTGAT CAAGTGTTTG CAGGACGTTA TTATTCATCT 
GAAAGTACAA GACCCAAGTT TCTAAGCAGA GATGTGGATT CTGAAATAAG TGACTTGGAG 
ACTGAGATTG AAAATAAAAA GGGCCACATA ATAACCCTTC AGCAGCGTCT GTCTGCGCTT 
GAGAAGGATA TCAAACGCAA TGAAGAACTT CTTAAAAGGT GCCAACTACA TTATAAAGAA 
ATAAAGATGA AAATAAGAAA AAATATTTCT GAAATTCGGG AACTTGAGAA TATAGAAGAA 
CACCAATCTG TAGATATTGC AACCTTGGAA GATGAAGCTG AAGAAAATAA AATAAAAATG 
CAAATGGTGG AGAAAAATAT GGAACAACAA AAAGAAAACA TGGAGAATCT TAAAAGTCTA 
AAAATTGAAG CAGAAAATAA GTATGATACA ATTAAATTGA AGATTAATCA GCTATCAGAG 
CTAGCGGATC CACTTAAGGA TGAGTTAAAT CTTGCTGACT CTGAAGTGGA TAGCCAGAAA 
CGAGGAAAGC AGCACTATGA GGATAAACAG AAAGAGCATT TGGATACCTT AAATAAAAAG 
AGACGAGAGC TTGACATGAA GGAAAAGGAG TTACAGGAGA AAATGTCACA GGCAAGACAG 
ATCTGCCCAG AACGGATAGA AGTAAAAAAA TCTGCATCAA TTCTAGACAA AGAAATAAAT 
CGATTAAGAC AAAAAATTCA GGCAGAACAT GCCAGTCATG GAGATCGGGA GGAAATAATG 
AAGCAGTATC AAGAAGCAAG AGAAACCTAC CTTGATCTGG ATAATAAAGT AAGGACTTTA 
AGAAGGTTCA TTAAATTGCT AGAAGAAATA ATGACCCATA GGTACAAAAC ATACCAACAA 
TTTAGAAGGT GTTTGACATT ACGATGCAAA TTATACTTTG ACAACTTATT ATCTCAGCGT 
GCTTATTGTG GAAAAATGAA TTTTGATCAC AAGAATGAAA CTCTTAGTAT AACAGTTCAG 
CCCGGAGAGG GGAACAAAGC CTCCTTCAAT GACATGCGTG CTTTGTCCGG CGGTGAGCGC 
TCTTTCTCCA CCGTGTGCTT CATCCTTTCC CTGTGGTCCA TTGCTGAATC ACCTTTCAGA 
TGCCTGGATG AGTTTGATGT CTACATGGAT ATGGTTAATA GGAGAATTGC GATGGACATG 
ATCCTTAAGA TGGCAGATTC CCAACGTTTT AGACAATTTA TCTTGCTTAC CCCTCAAAGC 
ATGAGCTCCC TTCCCTCAAG TAAACTGATT AGAATTCTTC GAATGTCTGA CCCTGAAAGA 
GGGCAAACCA CACTGCCCTT CCGACCTGTG ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( NM_001361252.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001348181.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu84264
Clone ID Related Accession (Same CDS sequence)	NM_001361252.1
Accession Version	NM_001361252.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090630.1 and AK011982.1. ##Evidence-Data-START## Transcript exon combination :: AK011982.1, SRR1660811.179813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTACTTC AAGCCTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001348181.1
CDS	409..1389
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVLQAS

Target ORF information:

RefSeq Version	NM_001361252.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001361252.1

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTACTTC AAGCCTCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( XM_011243892.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242194.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70104
Clone ID Related Accession (Same CDS sequence)	XM_011243892.2 , XM_011243892.3
Accession Version	XM_011243892.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011243892.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGTTA 
CAGAAGGCTA AGAAAGGGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242194.1
CDS	183..2906
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKLQKAKKGV

Target ORF information:

RefSeq Version	XM_011243892.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243892.2

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGTTA 
CAGAAGGCTA AGAAAGGGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( XM_011243892.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242194.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70104
Clone ID Related Accession (Same CDS sequence)	XM_011243892.2 , XM_011243892.3
Accession Version	XM_011243892.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2724bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011243892.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGTTA 
CAGAAGGCTA AGAAAGGGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242194.1
CDS	268..2991
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKLQKAKKGV

Target ORF information:

RefSeq Version	XM_011243892.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243892.3

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGTTA 
CAGAAGGCTA AGAAAGGGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( XM_006515173.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515236.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47376
Clone ID Related Accession (Same CDS sequence)	XM_006515173.2 , XM_006515173.3
Accession Version	XM_006515173.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3030bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006515173.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTAAAAG ACCAAGACAA GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG 
AATGTACAAT TTCTTTCACG AATGGAACAT CTACTTTGCT CAGCAGATAT CTCAATAACA 
TTAAGGAACA GAGGAGATGA TGCCTTCAGA GCAAATGTGT ATGGTGACTC TATAGTTGTG 
CAGCAACACA TTAGCGTGGA TGGAAGTCGA TCTTACAAAC TAAAAAGTGA AAAAGGCACC 
GTGGTTTCTA CTAGGAAAGA AGAGCTGATT GCAATTCTTG ACCATTTTAA CATCCAGGTG 
GATAATCCGG TTTCTGTTTT AACACAAGAG ATGAGCAAGC AGTTCTTACA GTCCAAAAAT 
GAGGGAGACA AATACAAATT CTTCATGAAA GCAACCCAGC TCGAACAGAT GAAGGAAGAT 
TATTCATATA TTATGGAAAC AAAAGAAAGA ACAAAGGAAC AAATAAATCA GGGAGAAGAG 
CGACTTACTG AACTAAAACG CCAGTGTTTG GAGAAAGAGG AACGTTTTCA AAATATTGCT 
GGTTTAAGTA CAATGAAGAC TAATTTAGAG TACTTGAAAC ATGAAATGGC TTGGGCAGTG 
GTCAATGAAA TTGAAAAACA ATTGAATGCT ATTCGAGACA ATATCAAAAT TGGAGAAGAA 
CGTGCTGCAA AACTTGACAG GAAAATGGAA GAGCAGCAGG TCAGACTTAA TGATGCAGAA 
AAAAAGTACA AAGATATACA AGATAAACTA GAAAAAATTA GTGAAGAGAC AAATGCACGA 
GCACCAGAAT GTATGGCATT GAAAACAGAT GTCATTGCAA GGACAAGAGC CTTTAATGAC 
GCTGAGGTTT TATATAACCG TTCCCTAAAT GAATATAAAG CATTAAAAAA AGATGGTGAA 
CAGCTTTGTA AAAGAATTGA AGAACTGAAG AAAAGTACTG ATCAGTCATT AGAACCAGAG 
CGATTGGAAA GGCAAAAAAG GATCTGCTGG TTAAAAGAGA AAGTCAAGGC CTTACAGGAT 
CAGGAACATA CAGTCAATCA GGAGGCTGAG CAGTTTGAGC AAGCCATAGA AAAGGACAAG 
CAAGAGCATG GCCGAGTTAG GAAAGAAGAT ATAGAAGTGA GACATGCACT CAACTATAAT 
CAGAGACAAT TGAAAGAACT GAAAGATAGT AAAACTGATC GACTAAAAAG ATTTGGTCCT 
CATGTTCCAG CTCTTCTGGA AGCAATAGAT GATGCTTACA GACGGAGACA ATTTACCCAT 
AAACCTATCG GCCCTTTAGG TGCTTGCATT CATCTACGGG ACCCTGAACT TGCTTTGGCC 
ATTGAATCTT GCTTAAAAGG ACTTCTGCAA GCCTATTGTT GCCATAATCA TGCTGATGAG 
AGAGTACTTC AGTCTTTGAT GAAAAAATTT TATCCACCAG GGACCTCTCG GCCACAGATA 
ATTGTGTCTG AGTTTCGGGA TGAGGTATAT GATGTGAGAC TCAGAGCTGC TTACCATCCA 
GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA ATAGACAATG CTGTTGTGGC AAACAGCCTG 
ATTGACATGC GGAGCATAGA GACAGTGCTG CTGATCAAAA ATAATTCTGT GGCTCGTGCA 
GTCATGCAAT CCCAAAAGCC ACCCAAAAAT TGTAGAGAAG CTTTTACTGC TGATGGTGAT 
CAAGTGTTTG CAGGACGTTA TTATTCATCT GAAAGTACAA GACCCAAGTT TCTAAGCAGA 
GATGTGGATT CTGAAATAAG TGACTTGGAG ACTGAGATTG AAAATAAAAA GGGCCACATA 
ATAACCCTTC AGCAGCGTCT GTCTGCGCTT GAGAAGGATA TCAAACGCAA TGAAGAACTT 
CTTAAAAGGT GCCAACTACA TTATAAAGAA ATAAAGATGA AAATAAGAAA AAATATTTCT 
GAAATTCGGG AACTTGAGAA TATAGAAGAA CACCAATCTG TAGATATTGC AACCTTGGAA 
GATGAAGCTG AAGAAAATAA AATAAAAATG CAAATGGTGG AGAAAAATAT GGAACAACAA 
AAAGAAAACA TGGAGAATCT TAAAAGTCTA AAAATTGAAG CAGAAAATAA GTATGATACA 
ATTAAATTGA AGATTAATCA GCTATCAGAG CTAGCGGATC CACTTAAGGA TGAGTTAAAT 
CTTGCTGACT CTGAAGTGGA TAGCCAGAAA CGAGGAAAGC AGCACTATGA GGATAAACAG 
AAAGAGCATT TGGATACCTT AAATAAAAAG AGACGAGAGC TTGACATGAA GGAAAAGGAG 
TTACAGGAGA AAATGTCACA GGCAAGACAG ATCTGCCCAG AACGGATAGA AGTAAAAAAA 
TCTGCATCAA TTCTAGACAA AGAAATAAAT CGATTAAGAC AAAAAATTCA GGCAGAACAT 
GCCAGTCATG GAGATCGGGA GGAAATAATG AAGCAGTATC AAGAAGCAAG AGAAACCTAC 
CTTGATCTGG ATAATAAAGT AAGGACTTTA AGAAGGTTCA TTAAATTGCT AGAAGAAATA 
ATGACCCATA GGTACAAAAC ATACCAACAA TTTAGAAGGT GTTTGACATT ACGATGCAAA 
TTATACTTTG ACAACTTATT ATCTCAGCGT GCTTATTGTG GAAAAATGAA TTTTGATCAC 
AAGAATGAAA CTCTTAGTAT AACAGTTCAG CCCGGAGAGG GGAACAAAGC CTCCTTCAAT 
GACATGCGTG CTTTGTCCGG CGGTGAGCGC TCTTTCTCCA CCGTGTGCTT CATCCTTTCC 
CTGTGGTCCA TTGCTGAATC ACCTTTCAGA TGCCTGGATG AGTTTGATGT CTACATGGAT 
ATGGTTAATA GGAGAATTGC GATGGACATG ATCCTTAAGA TGGCAGATTC CCAACGTTTT 
AGACAATTTA TCTTGCTTAC CCCTCAAAGC ATGAGCTCCC TTCCCTCAAG TAAACTGATT 
AGAATTCTTC GAATGTCTGA CCCTGAAAGA GGGCAAACCA CACTGCCCTT CCGACCTGTG 
ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515236.1
CDS	231..3260
Translation	MLKDQDKKNWKILIKMEMKMNVQFLSRMEHLLCSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	XM_006515173.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006515173.3

ORF Insert Sequence:

ATGCTAAAAG ACCAAGACAA GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG 
AATGTACAAT TTCTTTCACG AATGGAACAT CTACTTTGCT CAGCAGATAT CTCAATAACA 
TTAAGGAACA GAGGAGATGA TGCCTTCAGA GCAAATGTGT ATGGTGACTC TATAGTTGTG 
CAGCAACACA TTAGCGTGGA TGGAAGTCGA TCTTACAAAC TAAAAAGTGA AAAAGGCACC 
GTGGTTTCTA CTAGGAAAGA AGAGCTGATT GCAATTCTTG ACCATTTTAA CATCCAGGTG 
GATAATCCGG TTTCTGTTTT AACACAAGAG ATGAGCAAGC AGTTCTTACA GTCCAAAAAT 
GAGGGAGACA AATACAAATT CTTCATGAAA GCAACCCAGC TCGAACAGAT GAAGGAAGAT 
TATTCATATA TTATGGAAAC AAAAGAAAGA ACAAAGGAAC AAATAAATCA GGGAGAAGAG 
CGACTTACTG AACTAAAACG CCAGTGTTTG GAGAAAGAGG AACGTTTTCA AAATATTGCT 
GGTTTAAGTA CAATGAAGAC TAATTTAGAG TACTTGAAAC ATGAAATGGC TTGGGCAGTG 
GTCAATGAAA TTGAAAAACA ATTGAATGCT ATTCGAGACA ATATCAAAAT TGGAGAAGAA 
CGTGCTGCAA AACTTGACAG GAAAATGGAA GAGCAGCAGG TCAGACTTAA TGATGCAGAA 
AAAAAGTACA AAGATATACA AGATAAACTA GAAAAAATTA GTGAAGAGAC AAATGCACGA 
GCACCAGAAT GTATGGCATT GAAAACAGAT GTCATTGCAA GGACAAGAGC CTTTAATGAC 
GCTGAGGTTT TATATAACCG TTCCCTAAAT GAATATAAAG CATTAAAAAA AGATGGTGAA 
CAGCTTTGTA AAAGAATTGA AGAACTGAAG AAAAGTACTG ATCAGTCATT AGAACCAGAG 
CGATTGGAAA GGCAAAAAAG GATCTGCTGG TTAAAAGAGA AAGTCAAGGC CTTACAGGAT 
CAGGAACATA CAGTCAATCA GGAGGCTGAG CAGTTTGAGC AAGCCATAGA AAAGGACAAG 
CAAGAGCATG GCCGAGTTAG GAAAGAAGAT ATAGAAGTGA GACATGCACT CAACTATAAT 
CAGAGACAAT TGAAAGAACT GAAAGATAGT AAAACTGATC GACTAAAAAG ATTTGGTCCT 
CATGTTCCAG CTCTTCTGGA AGCAATAGAT GATGCTTACA GACGGAGACA ATTTACCCAT 
AAACCTATCG GCCCTTTAGG TGCTTGCATT CATCTACGGG ACCCTGAACT TGCTTTGGCC 
ATTGAATCTT GCTTAAAAGG ACTTCTGCAA GCCTATTGTT GCCATAATCA TGCTGATGAG 
AGAGTACTTC AGTCTTTGAT GAAAAAATTT TATCCACCAG GGACCTCTCG GCCACAGATA 
ATTGTGTCTG AGTTTCGGGA TGAGGTATAT GATGTGAGAC TCAGAGCTGC TTACCATCCA 
GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA ATAGACAATG CTGTTGTGGC AAACAGCCTG 
ATTGACATGC GGAGCATAGA GACAGTGCTG CTGATCAAAA ATAATTCTGT GGCTCGTGCA 
GTCATGCAAT CCCAAAAGCC ACCCAAAAAT TGTAGAGAAG CTTTTACTGC TGATGGTGAT 
CAAGTGTTTG CAGGACGTTA TTATTCATCT GAAAGTACAA GACCCAAGTT TCTAAGCAGA 
GATGTGGATT CTGAAATAAG TGACTTGGAG ACTGAGATTG AAAATAAAAA GGGCCACATA 
ATAACCCTTC AGCAGCGTCT GTCTGCGCTT GAGAAGGATA TCAAACGCAA TGAAGAACTT 
CTTAAAAGGT GCCAACTACA TTATAAAGAA ATAAAGATGA AAATAAGAAA AAATATTTCT 
GAAATTCGGG AACTTGAGAA TATAGAAGAA CACCAATCTG TAGATATTGC AACCTTGGAA 
GATGAAGCTG AAGAAAATAA AATAAAAATG CAAATGGTGG AGAAAAATAT GGAACAACAA 
AAAGAAAACA TGGAGAATCT TAAAAGTCTA AAAATTGAAG CAGAAAATAA GTATGATACA 
ATTAAATTGA AGATTAATCA GCTATCAGAG CTAGCGGATC CACTTAAGGA TGAGTTAAAT 
CTTGCTGACT CTGAAGTGGA TAGCCAGAAA CGAGGAAAGC AGCACTATGA GGATAAACAG 
AAAGAGCATT TGGATACCTT AAATAAAAAG AGACGAGAGC TTGACATGAA GGAAAAGGAG 
TTACAGGAGA AAATGTCACA GGCAAGACAG ATCTGCCCAG AACGGATAGA AGTAAAAAAA 
TCTGCATCAA TTCTAGACAA AGAAATAAAT CGATTAAGAC AAAAAATTCA GGCAGAACAT 
GCCAGTCATG GAGATCGGGA GGAAATAATG AAGCAGTATC AAGAAGCAAG AGAAACCTAC 
CTTGATCTGG ATAATAAAGT AAGGACTTTA AGAAGGTTCA TTAAATTGCT AGAAGAAATA 
ATGACCCATA GGTACAAAAC ATACCAACAA TTTAGAAGGT GTTTGACATT ACGATGCAAA 
TTATACTTTG ACAACTTATT ATCTCAGCGT GCTTATTGTG GAAAAATGAA TTTTGATCAC 
AAGAATGAAA CTCTTAGTAT AACAGTTCAG CCCGGAGAGG GGAACAAAGC CTCCTTCAAT 
GACATGCGTG CTTTGTCCGG CGGTGAGCGC TCTTTCTCCA CCGTGTGCTT CATCCTTTCC 
CTGTGGTCCA TTGCTGAATC ACCTTTCAGA TGCCTGGATG AGTTTGATGT CTACATGGAT 
ATGGTTAATA GGAGAATTGC GATGGACATG ATCCTTAAGA TGGCAGATTC CCAACGTTTT 
AGACAATTTA TCTTGCTTAC CCCTCAAAGC ATGAGCTCCC TTCCCTCAAG TAAACTGATT 
AGAATTCTTC GAATGTCTGA CCCTGAAAGA GGGCAAACCA CACTGCCCTT CCGACCTGTG 
ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( NM_025695.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079971.2 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 1, mRNA.

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CloneID	OMu13640
Clone ID Related Accession (Same CDS sequence)	NM_025695.4
Accession Version	NM_025695.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3294bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104880.13 and AC139207.10. On Nov 17, 2006 this sequence version replaced NM_025695.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC090630.1, SRR1660815.115634.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGCAG 
TATCAAGAAG CAAGAGAAAC CTACCTTGAT CTGGATAATA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TGCTAGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTTTGA CATTACGATG CAAATTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA TCACAAGAAT GAAACTCTTA GTATAACAGT TCAGCCCGGA 
GAGGGGAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGTGA GCGCTCTTTC 
TCCACCGTGT GCTTCATCCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAA TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCCCTTCCCT CAAGTAAACT GATTAGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACACTGC CCTTCCGACC TGTGACTCAA GAGGAAGATG ACAGTGCAAG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079971.2
CDS	409..3702
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	NM_025695.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025695.4

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTCTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAA 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG AATGTACAAT TTCTTTCACG 
AATGGAACAT CTACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GTCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAACGT CAACTTTGTT 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACCG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGGTCC TCTTTAAAAG GCTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGAGCAAAT 
GTGTATGGTG ACTCTATAGT TGTGCAGCAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACTAGGA AAGAAGAGCT GATTGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCGGTTTCTG TTTTAACACA AGAGATGAGC 
AAGCAGTTCT TACAGTCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAGCTCGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACAAAAGA AAGAACAAAG 
GAACAAATAA ATCAGGGAGA AGAGCGACTT ACTGAACTAA AACGCCAGTG TTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACTAATTT AGAGTACTTG 
AAACATGAAA TGGCTTGGGC AGTGGTCAAT GAAATTGAAA AACAATTGAA TGCTATTCGA 
GACAATATCA AAATTGGAGA AGAACGTGCT GCAAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAG TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CATTGAAAAC AGATGTCATT 
GCAAGGACAA GAGCCTTTAA TGACGCTGAG GTTTTATATA ACCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAACT GAAGAAAAGT 
ACTGATCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTCA AGGCCTTACA GGATCAGGAA CATACAGTCA ATCAGGAGGC TGAGCAGTTT 
GAGCAAGCCA TAGAAAAGGA CAAGCAAGAG CATGGCCGAG TTAGGAAAGA AGATATAGAA 
GTGAGACATG CACTCAACTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAATTTAC CCATAAACCT ATCGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCTTT GGCCATTGAA TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGTTGCCATA ATCATGCTGA TGAGAGAGTA CTTCAGTCTT TGATGAAAAA ATTTTATCCA 
CCAGGGACCT CTCGGCCACA GATAATTGTG TCTGAGTTTC GGGATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TGGCAAACAG CCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTGGCTCG TGCAGTCATG CAATCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGATGG TGATCAAGTG TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAGACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATAACC CTTCAGCAGC GTCTGTCTGC GCTTGAGAAG 
GATATCAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAATATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCTGAAGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAACA ACAAAAAGAA AACATGGAGA ATCTTAAAAG TCTAAAAATT 
GAAGCAGAAA ATAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCG 
GATCCACTTA AGGATGAGTT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGAGGA 
AAGCAGCACT ATGAGGATAA ACAGAAAGAG CATTTGGATA CCTTAAATAA AAAGAGACGA 
GAGCTTGACA TGAAGGAAAA GGAGTTACAG GAGAAAATGT CACAGGCAAG ACAGATCTGC 
CCAGAACGGA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT AAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCCAGT CATGGAGATC GGGAGGAAAT AATGAAGCAG 
TATCAAGAAG CAAGAGAAAC CTACCTTGAT CTGGATAATA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TGCTAGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTTTGA CATTACGATG CAAATTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA TCACAAGAAT GAAACTCTTA GTATAACAGT TCAGCCCGGA 
GAGGGGAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGTGA GCGCTCTTTC 
TCCACCGTGT GCTTCATCCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAA TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCCCTTCCCT CAAGTAAACT GATTAGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACACTGC CCTTCCGACC TGTGACTCAA GAGGAAGATG ACAGTGCAAG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( XM_006515173.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006515236.1 Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

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CloneID	OMu47376
Clone ID Related Accession (Same CDS sequence)	XM_006515173.2 , XM_006515173.3
Accession Version	XM_006515173.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3030bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	structural maintenance of chromosomes protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006515173.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTAAAAG ACCAAGACAA GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG 
AATGTACAAT TTCTTTCACG AATGGAACAT CTACTTTGCT CAGCAGATAT CTCAATAACA 
TTAAGGAACA GAGGAGATGA TGCCTTCAGA GCAAATGTGT ATGGTGACTC TATAGTTGTG 
CAGCAACACA TTAGCGTGGA TGGAAGTCGA TCTTACAAAC TAAAAAGTGA AAAAGGCACC 
GTGGTTTCTA CTAGGAAAGA AGAGCTGATT GCAATTCTTG ACCATTTTAA CATCCAGGTG 
GATAATCCGG TTTCTGTTTT AACACAAGAG ATGAGCAAGC AGTTCTTACA GTCCAAAAAT 
GAGGGAGACA AATACAAATT CTTCATGAAA GCAACCCAGC TCGAACAGAT GAAGGAAGAT 
TATTCATATA TTATGGAAAC AAAAGAAAGA ACAAAGGAAC AAATAAATCA GGGAGAAGAG 
CGACTTACTG AACTAAAACG CCAGTGTTTG GAGAAAGAGG AACGTTTTCA AAATATTGCT 
GGTTTAAGTA CAATGAAGAC TAATTTAGAG TACTTGAAAC ATGAAATGGC TTGGGCAGTG 
GTCAATGAAA TTGAAAAACA ATTGAATGCT ATTCGAGACA ATATCAAAAT TGGAGAAGAA 
CGTGCTGCAA AACTTGACAG GAAAATGGAA GAGCAGCAGG TCAGACTTAA TGATGCAGAA 
AAAAAGTACA AAGATATACA AGATAAACTA GAAAAAATTA GTGAAGAGAC AAATGCACGA 
GCACCAGAAT GTATGGCATT GAAAACAGAT GTCATTGCAA GGACAAGAGC CTTTAATGAC 
GCTGAGGTTT TATATAACCG TTCCCTAAAT GAATATAAAG CATTAAAAAA AGATGGTGAA 
CAGCTTTGTA AAAGAATTGA AGAACTGAAG AAAAGTACTG ATCAGTCATT AGAACCAGAG 
CGATTGGAAA GGCAAAAAAG GATCTGCTGG TTAAAAGAGA AAGTCAAGGC CTTACAGGAT 
CAGGAACATA CAGTCAATCA GGAGGCTGAG CAGTTTGAGC AAGCCATAGA AAAGGACAAG 
CAAGAGCATG GCCGAGTTAG GAAAGAAGAT ATAGAAGTGA GACATGCACT CAACTATAAT 
CAGAGACAAT TGAAAGAACT GAAAGATAGT AAAACTGATC GACTAAAAAG ATTTGGTCCT 
CATGTTCCAG CTCTTCTGGA AGCAATAGAT GATGCTTACA GACGGAGACA ATTTACCCAT 
AAACCTATCG GCCCTTTAGG TGCTTGCATT CATCTACGGG ACCCTGAACT TGCTTTGGCC 
ATTGAATCTT GCTTAAAAGG ACTTCTGCAA GCCTATTGTT GCCATAATCA TGCTGATGAG 
AGAGTACTTC AGTCTTTGAT GAAAAAATTT TATCCACCAG GGACCTCTCG GCCACAGATA 
ATTGTGTCTG AGTTTCGGGA TGAGGTATAT GATGTGAGAC TCAGAGCTGC TTACCATCCA 
GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA ATAGACAATG CTGTTGTGGC AAACAGCCTG 
ATTGACATGC GGAGCATAGA GACAGTGCTG CTGATCAAAA ATAATTCTGT GGCTCGTGCA 
GTCATGCAAT CCCAAAAGCC ACCCAAAAAT TGTAGAGAAG CTTTTACTGC TGATGGTGAT 
CAAGTGTTTG CAGGACGTTA TTATTCATCT GAAAGTACAA GACCCAAGTT TCTAAGCAGA 
GATGTGGATT CTGAAATAAG TGACTTGGAG ACTGAGATTG AAAATAAAAA GGGCCACATA 
ATAACCCTTC AGCAGCGTCT GTCTGCGCTT GAGAAGGATA TCAAACGCAA TGAAGAACTT 
CTTAAAAGGT GCCAACTACA TTATAAAGAA ATAAAGATGA AAATAAGAAA AAATATTTCT 
GAAATTCGGG AACTTGAGAA TATAGAAGAA CACCAATCTG TAGATATTGC AACCTTGGAA 
GATGAAGCTG AAGAAAATAA AATAAAAATG CAAATGGTGG AGAAAAATAT GGAACAACAA 
AAAGAAAACA TGGAGAATCT TAAAAGTCTA AAAATTGAAG CAGAAAATAA GTATGATACA 
ATTAAATTGA AGATTAATCA GCTATCAGAG CTAGCGGATC CACTTAAGGA TGAGTTAAAT 
CTTGCTGACT CTGAAGTGGA TAGCCAGAAA CGAGGAAAGC AGCACTATGA GGATAAACAG 
AAAGAGCATT TGGATACCTT AAATAAAAAG AGACGAGAGC TTGACATGAA GGAAAAGGAG 
TTACAGGAGA AAATGTCACA GGCAAGACAG ATCTGCCCAG AACGGATAGA AGTAAAAAAA 
TCTGCATCAA TTCTAGACAA AGAAATAAAT CGATTAAGAC AAAAAATTCA GGCAGAACAT 
GCCAGTCATG GAGATCGGGA GGAAATAATG AAGCAGTATC AAGAAGCAAG AGAAACCTAC 
CTTGATCTGG ATAATAAAGT AAGGACTTTA AGAAGGTTCA TTAAATTGCT AGAAGAAATA 
ATGACCCATA GGTACAAAAC ATACCAACAA TTTAGAAGGT GTTTGACATT ACGATGCAAA 
TTATACTTTG ACAACTTATT ATCTCAGCGT GCTTATTGTG GAAAAATGAA TTTTGATCAC 
AAGAATGAAA CTCTTAGTAT AACAGTTCAG CCCGGAGAGG GGAACAAAGC CTCCTTCAAT 
GACATGCGTG CTTTGTCCGG CGGTGAGCGC TCTTTCTCCA CCGTGTGCTT CATCCTTTCC 
CTGTGGTCCA TTGCTGAATC ACCTTTCAGA TGCCTGGATG AGTTTGATGT CTACATGGAT 
ATGGTTAATA GGAGAATTGC GATGGACATG ATCCTTAAGA TGGCAGATTC CCAACGTTTT 
AGACAATTTA TCTTGCTTAC CCCTCAAAGC ATGAGCTCCC TTCCCTCAAG TAAACTGATT 
AGAATTCTTC GAATGTCTGA CCCTGAAAGA GGGCAAACCA CACTGCCCTT CCGACCTGTG 
ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006515236.1
CDS	205..3234
Translation	MLKDQDKKNWKILIKMEMKMNVQFLSRMEHLLCSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	XM_006515173.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006515173.2

ORF Insert Sequence:

ATGCTAAAAG ACCAAGACAA GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAAGATG 
AATGTACAAT TTCTTTCACG AATGGAACAT CTACTTTGCT CAGCAGATAT CTCAATAACA 
TTAAGGAACA GAGGAGATGA TGCCTTCAGA GCAAATGTGT ATGGTGACTC TATAGTTGTG 
CAGCAACACA TTAGCGTGGA TGGAAGTCGA TCTTACAAAC TAAAAAGTGA AAAAGGCACC 
GTGGTTTCTA CTAGGAAAGA AGAGCTGATT GCAATTCTTG ACCATTTTAA CATCCAGGTG 
GATAATCCGG TTTCTGTTTT AACACAAGAG ATGAGCAAGC AGTTCTTACA GTCCAAAAAT 
GAGGGAGACA AATACAAATT CTTCATGAAA GCAACCCAGC TCGAACAGAT GAAGGAAGAT 
TATTCATATA TTATGGAAAC AAAAGAAAGA ACAAAGGAAC AAATAAATCA GGGAGAAGAG 
CGACTTACTG AACTAAAACG CCAGTGTTTG GAGAAAGAGG AACGTTTTCA AAATATTGCT 
GGTTTAAGTA CAATGAAGAC TAATTTAGAG TACTTGAAAC ATGAAATGGC TTGGGCAGTG 
GTCAATGAAA TTGAAAAACA ATTGAATGCT ATTCGAGACA ATATCAAAAT TGGAGAAGAA 
CGTGCTGCAA AACTTGACAG GAAAATGGAA GAGCAGCAGG TCAGACTTAA TGATGCAGAA 
AAAAAGTACA AAGATATACA AGATAAACTA GAAAAAATTA GTGAAGAGAC AAATGCACGA 
GCACCAGAAT GTATGGCATT GAAAACAGAT GTCATTGCAA GGACAAGAGC CTTTAATGAC 
GCTGAGGTTT TATATAACCG TTCCCTAAAT GAATATAAAG CATTAAAAAA AGATGGTGAA 
CAGCTTTGTA AAAGAATTGA AGAACTGAAG AAAAGTACTG ATCAGTCATT AGAACCAGAG 
CGATTGGAAA GGCAAAAAAG GATCTGCTGG TTAAAAGAGA AAGTCAAGGC CTTACAGGAT 
CAGGAACATA CAGTCAATCA GGAGGCTGAG CAGTTTGAGC AAGCCATAGA AAAGGACAAG 
CAAGAGCATG GCCGAGTTAG GAAAGAAGAT ATAGAAGTGA GACATGCACT CAACTATAAT 
CAGAGACAAT TGAAAGAACT GAAAGATAGT AAAACTGATC GACTAAAAAG ATTTGGTCCT 
CATGTTCCAG CTCTTCTGGA AGCAATAGAT GATGCTTACA GACGGAGACA ATTTACCCAT 
AAACCTATCG GCCCTTTAGG TGCTTGCATT CATCTACGGG ACCCTGAACT TGCTTTGGCC 
ATTGAATCTT GCTTAAAAGG ACTTCTGCAA GCCTATTGTT GCCATAATCA TGCTGATGAG 
AGAGTACTTC AGTCTTTGAT GAAAAAATTT TATCCACCAG GGACCTCTCG GCCACAGATA 
ATTGTGTCTG AGTTTCGGGA TGAGGTATAT GATGTGAGAC TCAGAGCTGC TTACCATCCA 
GAGTTTCCAA CTGTTCTGAC AGCTTTAGAA ATAGACAATG CTGTTGTGGC AAACAGCCTG 
ATTGACATGC GGAGCATAGA GACAGTGCTG CTGATCAAAA ATAATTCTGT GGCTCGTGCA 
GTCATGCAAT CCCAAAAGCC ACCCAAAAAT TGTAGAGAAG CTTTTACTGC TGATGGTGAT 
CAAGTGTTTG CAGGACGTTA TTATTCATCT GAAAGTACAA GACCCAAGTT TCTAAGCAGA 
GATGTGGATT CTGAAATAAG TGACTTGGAG ACTGAGATTG AAAATAAAAA GGGCCACATA 
ATAACCCTTC AGCAGCGTCT GTCTGCGCTT GAGAAGGATA TCAAACGCAA TGAAGAACTT 
CTTAAAAGGT GCCAACTACA TTATAAAGAA ATAAAGATGA AAATAAGAAA AAATATTTCT 
GAAATTCGGG AACTTGAGAA TATAGAAGAA CACCAATCTG TAGATATTGC AACCTTGGAA 
GATGAAGCTG AAGAAAATAA AATAAAAATG CAAATGGTGG AGAAAAATAT GGAACAACAA 
AAAGAAAACA TGGAGAATCT TAAAAGTCTA AAAATTGAAG CAGAAAATAA GTATGATACA 
ATTAAATTGA AGATTAATCA GCTATCAGAG CTAGCGGATC CACTTAAGGA TGAGTTAAAT 
CTTGCTGACT CTGAAGTGGA TAGCCAGAAA CGAGGAAAGC AGCACTATGA GGATAAACAG 
AAAGAGCATT TGGATACCTT AAATAAAAAG AGACGAGAGC TTGACATGAA GGAAAAGGAG 
TTACAGGAGA AAATGTCACA GGCAAGACAG ATCTGCCCAG AACGGATAGA AGTAAAAAAA 
TCTGCATCAA TTCTAGACAA AGAAATAAAT CGATTAAGAC AAAAAATTCA GGCAGAACAT 
GCCAGTCATG GAGATCGGGA GGAAATAATG AAGCAGTATC AAGAAGCAAG AGAAACCTAC 
CTTGATCTGG ATAATAAAGT AAGGACTTTA AGAAGGTTCA TTAAATTGCT AGAAGAAATA 
ATGACCCATA GGTACAAAAC ATACCAACAA TTTAGAAGGT GTTTGACATT ACGATGCAAA 
TTATACTTTG ACAACTTATT ATCTCAGCGT GCTTATTGTG GAAAAATGAA TTTTGATCAC 
AAGAATGAAA CTCTTAGTAT AACAGTTCAG CCCGGAGAGG GGAACAAAGC CTCCTTCAAT 
GACATGCGTG CTTTGTCCGG CGGTGAGCGC TCTTTCTCCA CCGTGTGCTT CATCCTTTCC 
CTGTGGTCCA TTGCTGAATC ACCTTTCAGA TGCCTGGATG AGTTTGATGT CTACATGGAT 
ATGGTTAATA GGAGAATTGC GATGGACATG ATCCTTAAGA TGGCAGATTC CCAACGTTTT 
AGACAATTTA TCTTGCTTAC CCCTCAAAGC ATGAGCTCCC TTCCCTCAAG TAAACTGATT 
AGAATTCTTC GAATGTCTGA CCCTGAAAGA GGGCAAACCA CACTGCCCTT CCGACCTGTG 
ACTCAAGAGG AAGATGACAG TGCAAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.
Development (Cambridge, England)144(9)1648-1660(2017 05)
Hwang G,Sun F,O'Brien M,Eppig JJ,Handel MA,Jordan PW

Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.
Cell death & disease4e749(2013 Aug)
Verver DE,van Pelt AM,Repping S,Hamer G

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.
DNA repair12(5)356-66(2013 May)
Ju L,Wing J,Taylor E,Brandt R,Slijepcevic P,Horsch M,Rathkolb B,R?cz I,Becker L,Hans W,Adler T,Beckers J,Rozman J,Klingenspor M,Wolf E,Zimmer A,Klopstock T,Busch DH,Gailus-Durner V,Fuchs H,de Angelis MH,van der Horst G,Lehmann AR

Telomeric DNA mediates de novo PML body formation.
Molecular biology of the cell20(22)4804-15(2009 Nov)
Brouwer AK,Schimmel J,Wiegant JC,Vertegaal AC,Tanke HJ,Dirks RW

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.
Molecular biology of the cell12(6)1583-94(2001 Jun)
Taylor EM,Moghraby JS,Lees JH,Smit B,Moens PB,Lehmann AR

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Smc6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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